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M. leprae Br4923 MLBr_02253 (-)

annotation: antigen 84 homolog
coordinates: 2676244 - 2676459
length: 71

PNNIAFSRSYIGKRCYSEQEVGVFIDLAEQERTRHIEEDVEFRNRNAELRNQDGAPQPRSCADRARNCHV
*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_02253--100% (71)antigen 84 homolog
M. leprae Br4923MLBr_00922ag847e-0949.02% (51) immunogenic protein, antigen 84

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2169cwag319e-0954.17% (48) hypothetical protein Mb2169c
M. gilvum PYR-GCKMflv_2996-7e-0949.06% (53) DivIVA family protein
M. tuberculosis H37RvRv2145cwag311e-0854.17% (48) hypothetical protein Rv2145c
M. abscessus ATCC 19977MAB_2017-3e-0852.08% (48) immunogenic protein antigen 84
M. marinum MMMAR_3185wag313e-0956.25% (48) secreted antigen Wag31
M. avium 104MAV_2345-3e-0846.03% (63) Wag31 protein
M. smegmatis MC2 155MSMEG_4217-2e-0956.25% (48) DivIVA protein
M. thermoresistible (build 8)TH_2373wag314e-0954.17% (48) CONSERVED HYPOTHETICAL PROTEIN WAG31
M. ulcerans Agy99MUL_3493wag312e-0956.25% (48) secreted antigen Wag31
M. vanbaalenii PYR-1Mvan_3515-9e-0954.17% (48) DivIVA family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb2169c|M.bovis_AF2122/97           MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELTRLIEENSDLR
Rv2145c|M.tuberculosis_H37Rv        MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELTRLIEENSDLR
MMAR_3185|M.marinum_M               MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELTRLIEENSDLR
MUL_3493|M.ulcerans_Agy99           MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELTRLIEENSDLR
MAV_2345|M.avium_104                ----------MAFSKPPIGKRGYNEDEVDAFLDLVEAELTRLIEENSDLR
MAB_2017|M.abscessus_ATCC_1997      MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELARLIEENSDLR
Mflv_2996|M.gilvum_PYR-GCK          MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELSRLIEENSDLR
Mvan_3515|M.vanbaalenii_PYR-1       MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELSRLIEENSDLR
MSMEG_4217|M.smegmatis_MC2_155      MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELTRLIEENADLR
TH_2373|M.thermoresistible__bu      MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELARLIEENTDLR
MLBr_02253|M.leprae_Br4923          MP------NNIAFSRSYIGKRCYSEQEVGVFIDLAEQERTRHIEEDVEFR
                                              :***:. **** *.*:**..*:**.* * :* ***: ::*

Mb2169c|M.bovis_AF2122/97           QRINELDQELAAG--GG--AGVTPQATQAIP--AYEPEPGK-----PAPA
Rv2145c|M.tuberculosis_H37Rv        QRINELDQELAAG--GG--AGVTPQATQAIP--AYEPEPGK-----PAPA
MMAR_3185|M.marinum_M               QRIAELDQELAAG--AGGGAAVTAQPTQAMP--VYEPEPEP-----AKPA
MUL_3493|M.ulcerans_Agy99           QRIAELDQELAAG--AGGGAAVTAQPTQAMP--VYEPEPEP-----AKPA
MAV_2345|M.avium_104                QRIEELDQELAAG--GGAAAPAAAAPTQAIP--VAEPEPVK-----AAPA
MAB_2017|M.abscessus_ATCC_1997      QRVQELDQELAEARKGGGAAPVYEAPKPEKKPEPAKPEPTP-----APVV
Mflv_2996|M.gilvum_PYR-GCK          QRISELDHELGQARAGGAAAQPTQTIPAYEPEPEPAPEPEPEPVYEAPAP
Mvan_3515|M.vanbaalenii_PYR-1       QRVAELDQELSAARRGEGGVQATQTLPVYEPEPEPAPAPEP--VYEA-AP
MSMEG_4217|M.smegmatis_MC2_155      QRVAELDQELAAAR---SGAGASSQATSSIPLYEPEPEPAPAPPQPVYEA
TH_2373|M.thermoresistible__bu      QRVAELDQELQAAR----AAAGGGQSTQAIPLYQPEPEPEP-------AP
MLBr_02253|M.leprae_Br4923          NRNAELRNQ------------------------DGAPQP-----------
                                    :*  ** ::                           * *           

Mb2169c|M.bovis_AF2122/97           AVSAG--MNEEQALKAARVLSLAQDTADRLTNTAKAESDKMLADARANAE
Rv2145c|M.tuberculosis_H37Rv        AVSAG--MNEEQALKAARVLSLAQDTADRLTNTAKAESDKMLADARANAE
MMAR_3185|M.marinum_M               APVASAATNEEQAMKAARVLSLAQDTADRLTSTAKAESDKMLSDARANAD
MUL_3493|M.ulcerans_Agy99           APVASAATNEEQAMKAARVLSLAQDTADRLTSTAKAESDKMLSDARANAD
MAV_2345|M.avium_104                AAVS----NEEQAIKAARVLSLAQDTADRLTSTAQAESEKMLADARANAD
MAB_2017|M.abscessus_ATCC_1997      AAAPAGASTEEHHVRAAKILGLAQDTADRLTGNAKSESEKMLADARANAD
Mflv_2996|M.gilvum_PYR-GCK          AAQQAAPATEDQHLRAAKVLSLAQDTADRLTSSAKAESEKMLADARAQAD
Mvan_3515|M.vanbaalenii_PYR-1       TPAPAAPVTEDQHLRAAKVLSLAQDTADRLTSSAKAESEKMLSDARAQAD
MSMEG_4217|M.smegmatis_MC2_155      PAQPAAPQSEDTAVRAARVLSLAQDTADRLTSTAKAEADKLLSDARAQAE
TH_2373|M.thermoresistible__bu      QPEQSTAVSEDQHLKAAKVLSLAQDTADRLTSTAKAESEKMLADARAQAD
MLBr_02253|M.leprae_Br4923          -----------------------RSCADRARNCHV---------------
                                                           :. ***  .                  

Mb2169c|M.bovis_AF2122/97           QILGEARHTADATVAEARQRADAMLADAQSRSEAQLRQAQEKADALQADA
Rv2145c|M.tuberculosis_H37Rv        QILGEARHTADATVAEARQRADAMLADAQSRSEAQLRQAQEKADALQADA
MMAR_3185|M.marinum_M               QILSEARHTAETTVTEARQRADGMLADAQARSESQLRQAQEKADALQADA
MUL_3493|M.ulcerans_Agy99           QILSEARHTAETTVTEARQRADGMLADAQARSESQLRQAQEKADALQADA
MAV_2345|M.avium_104                QILSEARSTAETTVAEARQRADAMLADAQARSEAQLRQAQEKADALQADA
MAB_2017|M.abscessus_ATCC_1997      QIVSEARATAEKTVTEARTKAEALLSDAQTRSETQLRQAQEKADALQSDA
Mflv_2996|M.gilvum_PYR-GCK          QLVTEARQTAETTVTEARQRADAMLADAQSRSETQLRQAQEKADALQADA
Mvan_3515|M.vanbaalenii_PYR-1       QMVTEARQTAETTVAEARQRADAMLADAQNRSETQLRQAQEKADALQADA
MSMEG_4217|M.smegmatis_MC2_155      AMVSDARQTAETTVSEARQRADAMLADAQTRSEAQLRQAQEKADALQADA
TH_2373|M.thermoresistible__bu      AMIAEARSTAETTIADARQRSEAMLNDAKTRSEAQLRQAQEKADALQADA
MLBr_02253|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2169c|M.bovis_AF2122/97           ERKHSEIMGTINQQRAVLEGRLEQLRTFEREYRTRLKTYLESQLEELGQR
Rv2145c|M.tuberculosis_H37Rv        ERKHSEIMGTINQQRAVLEGRLEQLRTFEREYRTRLKTYLESQLEELGQR
MMAR_3185|M.marinum_M               ERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLEELGQR
MUL_3493|M.ulcerans_Agy99           ERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLEELGQR
MAV_2345|M.avium_104                ERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLEELGQR
MAB_2017|M.abscessus_ATCC_1997      ERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLEELGQR
Mflv_2996|M.gilvum_PYR-GCK          ERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLEELGTR
Mvan_3515|M.vanbaalenii_PYR-1       ERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLEELGQR
MSMEG_4217|M.smegmatis_MC2_155      ERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLEELGQR
TH_2373|M.thermoresistible__bu      ERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLEELGQR
MLBr_02253|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb2169c|M.bovis_AF2122/97           GSAAPVDSNADAG------GFDQFNRGKN-
Rv2145c|M.tuberculosis_H37Rv        GSAAPVDSNADAG------GFDQFNRGKN-
MMAR_3185|M.marinum_M               GSAAPVDSSADAG------GFEQFNRGNN-
MUL_3493|M.ulcerans_Agy99           GSAAPVDSSADAG------GFEQFNRGNN-
MAV_2345|M.avium_104                GSAAPVDSSADAG------GFDQFNRGNN-
MAB_2017|M.abscessus_ATCC_1997      GSAAPVDAGASNENASKEAGFGQFNRGNNY
Mflv_2996|M.gilvum_PYR-GCK          GSAAPVDTGANND-----GGVNQFNRGNN-
Mvan_3515|M.vanbaalenii_PYR-1       GSAAPVDSGANND-----GGFNQFNRGNN-
MSMEG_4217|M.smegmatis_MC2_155      GSAAPVDSSANSDAS----GFGQFNRGNN-
TH_2373|M.thermoresistible__bu      GSAAPVDSTANSDSG----AFNQFTRGSN-
MLBr_02253|M.leprae_Br4923          ------------------------------