For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. avium 104 MAV_0189 (-)

annotation: phosphoglycerate mutase family protein
coordinates: 181963 - 182658
length: 231

VSGRLILVRHGQSYGNVERRLDTRPPGAELTPLGRDQAREFARRSGRPAMLAHSVATRASQTAAVIGGQL
ALPPVELGGIHEVQVGRLENRNDDEAVAEFNAIYERWHRGELEVPLPGGETGSEVLDRYLPVLTELRLRY
LDDHDFHGDIVVVSHGAAIRLAAAVLAGVEADFALDHHLDNAQSVALTPITDGRWSCVRWGTLTPPFYPE
AAEIPATPVADAVRSTTDPMG

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. avium 104 MAV_0189 - - 100% (231) phosphoglycerate mutase family protein
M. avium 104 MAV_4339 - 4e-15 28.79% (198) phosphoglycerate mutase family protein
M. avium 104 MAV_2211 - 2e-09 33.16% (196) bifunctional RNase H/acid phosphatase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3867c - 7e-96 72.84% (232) phosphoglycerate mutase
M. gilvum PYR-GCK Mflv_1146 - 2e-83 64.83% (236) phosphoglycerate mutase
M. tuberculosis H37Rv Rv3837c - 7e-96 72.84% (232) phosphoglycerate mutase
M. leprae Br4923 MLBr_00079 - 2e-92 67.97% (231) putative phosphoglycerate mutase
M. abscessus ATCC 19977 MAB_0133 - 1e-70 56.84% (234) phosphoglycerate mutase
M. marinum M MMAR_5389 - 1e-88 71.12% (232) phosphoglycerate mutase
M. smegmatis MC2 155 MSMEG_6416 - 1e-87 67.67% (232) phosphoglycerate mutase family protein
M. thermoresistible (build 8) TH_1473 - 3e-79 63.36% (232) PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE)
M. ulcerans Agy99 MUL_5010 - 1e-86 69.40% (232) phosphoglycerate mutase
M. vanbaalenii PYR-1 Mvan_5661 - 3e-81 63.03% (238) phosphoglycerate mutase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1146|M.gilvum_PYR-GCK          -----------MTGRLVLVRHGQSHANVERRLDTRPPGAELTDLGRDQAR
Mvan_5661|M.vanbaalenii_PYR-1       -----------MSGRLVLVRHGQSHGNVARRLDTRPPGAELTDLGREQAR
Mb3867c|M.bovis_AF2122/97           -----------MSGRLVLLRHGQSYGNVERRLDTLPPGTALTPLGRDQAR
Rv3837c|M.tuberculosis_H37Rv        -----------MSGRLVLLRHGQSYGNVERRLDTLPPGTALTPLGRDQAR
MLBr_00079|M.leprae_Br4923          -----------MSSRLVLLRHGQSYGNVEGRLDTRPPGASLTPFGRDQAR
MMAR_5389|M.marinum_M               -----------MSGRLVLVRHGQSVSNVERRLDTLPPGAELTPTGRVQAQ
MUL_5010|M.ulcerans_Agy99           -----------MSGRLVLVRHGQSVSNVERRLDTLPPGAELTPTGRAQAQ
MAV_0189|M.avium_104                -----------MSGRLILVRHGQSYGNVERRLDTRPPGAELTPLGRDQAR
MSMEG_6416|M.smegmatis_MC2_155      -----------MSGRLVLVRHGQSRANVDRRLDTRPPGAELTDLGHDQAR
MAB_0133|M.abscessus_ATCC_1997      MARRDAGREAAMSGRLVLVRHGQSYGNVERRLDTKPPGAALTELGLQQAR
TH_1473|M.thermoresistible__bu      -----------MSGRLVLVRHGQSQANVERRLDTAPPGAELTDLGRQQAR
                                               *:.**:*:***** .**  **** ***: **  *  **:

Mflv_1146|M.gilvum_PYR-GCK          TFARTLAR-PAAIVTHSIATRAVQTAGHIAAEFGGALS--AGAMAFEGLH
Mvan_5661|M.vanbaalenii_PYR-1       TFARELTR-PPAMVTHSIATRAVQTAGHIYSELSGVIRSQSGTLEFEGLH
Mb3867c|M.bovis_AF2122/97           AFARSGCR-RPALLAHSVAIRAYQTAAVVAAELD------MVAHEVAGIH
Rv3837c|M.tuberculosis_H37Rv        AFARSGCR-RPALLAHSVAIRAYQTAAVVAAELD------MVAHEVAGIH
MLBr_00079|M.leprae_Br4923          VFAQAAG--RPVLLVHSVAIRALETAAVLGAEFD------VPIREIAGIH
MMAR_5389|M.marinum_M               AFARGGLI-RPAVLVHSIATRASQTAEVIAAELA------VSAHEVVGIH
MUL_5010|M.ulcerans_Agy99           AFARGGLI-RPAMLVHSIATRASQAAEVVAAVLT------VSAHEVVGIH
MAV_0189|M.avium_104                EFARRSG--RPAMLAHSVATRASQTAAVIGGQLA------LPPVELGGIH
MSMEG_6416|M.smegmatis_MC2_155      RVVTAFPR-RPALVAHSVARRAAQTASGIAGEIG------LTPQEFDGVH
MAB_0133|M.abscessus_ATCC_1997      LFAKRYEEHAPAVLVHSVAVRAVQTAAGIAEHLG------VQAEQIEGLH
TH_1473|M.thermoresistible__bu      AFARQLRR-PPGLLVHSVAVRAEQTAGEAGSHLG------QQAHVFEGIH
                                     ..       . ::.**:* ** ::*      :            . *:*

Mflv_1146|M.gilvum_PYR-GCK          EVQVGELEDRTDEAAHDEFNAVYRRWHGGELDVALPGGETAQQVLDRYVP
Mvan_5661|M.vanbaalenii_PYR-1       EVQVGHLEDRCDEAAHDEFNAIYQRWHGGELDLAMPGGESAQQVLDRYVP
Mb3867c|M.bovis_AF2122/97           EVQVGELENRNDDEAVAEFNATYSRWHRGELDVPLPGGETANDVLDRYLP
Rv3837c|M.tuberculosis_H37Rv        EVQVGELENRNDDEAVAEFNATYSRWHRGELDVPLPGGETANDVLDRYLP
MLBr_00079|M.leprae_Br4923          EVQVGELENRNDDDAIAEFNAIYDRWHHGELDVPLPGGETANDVLDRYLP
MMAR_5389|M.marinum_M               EVQVGELENRCDDEAVAEFNAIYKRWHCGELDVPLPGGESANDVLARYVP
MUL_5010|M.ulcerans_Agy99           EVQVGELENRCDDEAAAEFNAIYKRWHCGELDVPLPGGESANDVLARYVP
MAV_0189|M.avium_104                EVQVGRLENRNDDEAVAEFNAIYERWHRGELEVPLPGGETGSEVLDRYLP
MSMEG_6416|M.smegmatis_MC2_155      EVQVGELEDRNDDVAIAQFEAIYQRWHQGELEVPMPGGESAVDVLDRYVP
MAB_0133|M.abscessus_ATCC_1997      EVQAGELEDRTDLEAFAVFDRTYERWHFGDLDARMPGGESAQDVFDRYLP
TH_1473|M.thermoresistible__bu      EVQAGELENRNDDEAITEFETVYQQWHQGNLKVNMPGGENGVEVLDRYVS
                                    ***.*.**:* *  *   *:  * :** *:*.  :****.. :*: **:.

Mflv_1146|M.gilvum_PYR-GCK          VLDQLRMRYLDDETWHGDIVVVSHGAAIRLVSALLAGVDSRFAVDHHLAN
Mvan_5661|M.vanbaalenii_PYR-1       VLEQLRMRYLEDGSWHGDIVVVSHGAAIRLVAAVLAGVDSGFAVDHHLAN
Mb3867c|M.bovis_AF2122/97           VLADLRMRYLDDGDWDGDIVVVSHSAAIRLAAAVLAGVDGNFVLDNHLEN
Rv3837c|M.tuberculosis_H37Rv        VLADLRMRYLDDGDWDGDIVVVSHSAAIRLAAAVLAGVDGNFVLDNHLEN
MLBr_00079|M.leprae_Br4923          VLVDLRMRYLDDGDWTGDVVVVSHGAAIRLVSAVLAEVDGRFALENRVNN
MMAR_5389|M.marinum_M               VLNDLRMRYLDDEDRTGDLVVVSHGAAIRLAGAVLAGVDANFALDNHLDN
MUL_5010|M.ulcerans_Agy99           VLNDLRMRYLDDEDRTGDLVVVSHGAAIRPAGAVLAGVDANFALDNHLDN
MAV_0189|M.avium_104                VLTELRLRYLDDHDFHGDIVVVSHGAAIRLAAAVLAGVEADFALDHHLDN
MSMEG_6416|M.smegmatis_MC2_155      VVDHLRLNYLDDHDFDSDIVLVSHGAAIRLVAAVLAGVDGSFALEHHLAN
MAB_0133|M.abscessus_ATCC_1997      AVADLRLRHLENDASTGDVVIVSHGAAIRLVAAALAGVDPGFAVNRHLRN
TH_1473|M.thermoresistible__bu      VITQLRLHYLDNDAWTDDIVVVSHGAAIRLVAATLAGVDSTFALDRHLGN
                                    .: .**:.:*::    .*:*:***.**** ..* ** *:  *.::.:: *

Mflv_1146|M.gilvum_PYR-GCK          TESVVLAPITDGRWSCVQWGKLTPPFVGDAPVTTTAG---DAPRSADPMG
Mvan_5661|M.vanbaalenii_PYR-1       TESVVLAPVTEGRWSCVQWGKLTPPFGPEAPVVTSP----EAAQSADPMG
Mb3867c|M.bovis_AF2122/97           VESVVLAPITDGRWSCVQWGLRKPPFCPDPAEAAASPVTHAVTSSTDPMG
Rv3837c|M.tuberculosis_H37Rv        VESVVLAPITDGRWSCVQWGLRKPPFCPDPAEAAASPVTHAVTSSTDPMG
MLBr_00079|M.leprae_Br4923          AESVVLVPVTDGRWSCVRWGALTPPFYPHLHRPDSTLVTDVVMSGRDSLG
MMAR_5389|M.marinum_M               AESVVLTPITDGRWSCVRWGTKTPPFCAEVDSAAG----DLMASSGDPMG
MUL_5010|M.ulcerans_Agy99           AESVVLTPITDGRWSCVRWGTKTPPFCAEVDSAAG----DLMASSGDPMG
MAV_0189|M.avium_104                AQSVALTPITDGRWSCVRWGTLTPPFYPEAAEIPATPVADAVRSTTDPMG
MSMEG_6416|M.smegmatis_MC2_155      TESVILTPTTDGRWSCVRWATLTPPFHPEPDVQPVT---DALTS-KDPMG
MAB_0133|M.abscessus_ATCC_1997      AEAVVLAPVTDGRWSCVHWGDAVAPF-PHQEAASA----EELAQSADPMG
TH_1473|M.thermoresistible__bu      TESVVLAPITDGRWSCLQWGKESPPFYPEPDVQPV----EDALHSVDPMG
                                    .::* *.* *:*****::*.   .**  .                 *.:*

species	id	gene	e-value	identity (len)	annotation
M. avium 104	MAV_0189	-	-	100% (231)	phosphoglycerate mutase family protein
M. avium 104	MAV_4339	-	4e-15	28.79% (198)	phosphoglycerate mutase family protein
M. avium 104	MAV_2211	-	2e-09	33.16% (196)	bifunctional RNase H/acid phosphatase