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QLRHLSIPFLVAEAGGDPWSIDSGLQAGRPAQIASLARAFHDAGMSTAEADVAFAAARGRFEASWNHRNG ALPINDSAEVQRVTRALAVEGRQLPRIATDLETIAAVLAESQRTSTWYIEALEYDLAAIDDEIGQALEEA DHCAAEELRYSAVTETKAITLVLEQIRESYSRLLHSALARLQADGVDPANVRGVDELSIPPADTGPEQVK WWWDSLSAAQQRLLIDQHPQELGNLNGIPAEARDSVNRATMTDDLSKVEAVARVRGVSVQALRDNALHNR DIDMFRNPAAYGLCATDIVRYQNAVKTNDCLNKACDPGLPLMLWAYDPLAFAGKGRAGIAIGNPDKSRNT AVVVPGTNSSVRGGWMSDGADDAINLYTQAQRADPHHATAVLAWMGYDAPEFDDSHWEQAVTDPAKLEQV GTPWRARQAGVLLAGDVNGLAATHDAGSRAHVTVIGHSYGSTTVADAFANSGMRANDAVLTGCPGTDLAH SAADFHLDGGRLYVGAASTDAISWIGESGSGLPNGLNETLGGPLGPFAGLGTDPAHAGFGAARFRAEVAG SHSVMPWFTDHSDYYDVGSEALHNMTEIVTGRGNELAAEGMLAPDRNAARVSILGRVHTPLGTLSLPRVE IRMPVVVDPEWERPARSVTNEHGF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5292 | - | - | 100% (655) | hypothetical protein MAV_5292 |
| M. avium 104 | MAV_1467 | - | 6e-57 | 32.88% (590) | hypothetical protein MAV_1467 |
| M. avium 104 | MAV_5295 | - | 2e-43 | 50.00% (188) | hypothetical protein MAV_5295 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2105 | - | 1e-172 | 51.53% (687) | hypothetical protein Mb2105 |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2079 | - | 1e-172 | 51.53% (687) | hypothetical protein Rv2079 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_5468 | - | 1e-173 | 51.24% (687) | hypothetical protein MMAR_5468 |
| M. smegmatis MC2 155 | MSMEG_6381 | - | 2e-27 | 28.72% (376) | hypothetical protein MSMEG_6381 |
| M. thermoresistible (build 8) | TH_2235 | - | 1e-124 | 50.41% (488) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_5057 | - | 1e-170 | 50.80% (687) | hypothetical protein MUL_5057 |
| M. vanbaalenii PYR-1 | Mvan_0049 | - | 1e-134 | 51.68% (505) | hypothetical protein Mvan_0049 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2105|M.bovis_AF2122/97 --------------------------------------------MQLRHI
Rv2079|M.tuberculosis_H37Rv --------------------------------------------MQLRHI
MMAR_5468|M.marinum_M MSSADAGYRPRFAVAAGATQRTSHAARINHLERLESRHDAVDGAMQLRYI
MUL_5057|M.ulcerans_Agy99 --------------------------------------------MQPRYI
MAV_5292|M.avium_104 --------------------------------------------MQLRHL
TH_2235|M.thermoresistible__bu --------------------------------------------------
Mvan_0049|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6381|M.smegmatis_MC2_155 --------------------------------------------------
Mb2105|M.bovis_AF2122/97 NIRALIAEAGGDPWAIEHSLHAGRPAQIAELAEAFHAAGRCTAEANAAFE
Rv2079|M.tuberculosis_H37Rv NIRALIAEAGGDPWAIEHSLHAGRPAQIAELAEAFHAAGRYTAEANAAFE
MMAR_5468|M.marinum_M SIPLLIAEAGGDPWAINQSLQLGRPAQISDLATAFHDAGRSTTEADTAFE
MUL_5057|M.ulcerans_Agy99 SNPLLIAEAGGGPWAINQSLQLGRPAQISDLATAFHDAGRSTTEADTAFE
MAV_5292|M.avium_104 SIPFLVAEAGGDPWSIDSGLQAGRPAQIASLARAFHDAGMSTAEADVAFA
TH_2235|M.thermoresistible__bu ---------------VSVSVSTVEAANPAGLLQAAGTLNDKITQLDTTLA
Mvan_0049|M.vanbaalenii_PYR-1 ---------------MAVSVSTVRDSKPDRLVDAADATGRHRSELQTIIA
MSMEG_6381|M.smegmatis_MC2_155 --------------MQLSDIDSWNVGALQSIAFELRDELRTIEGVATDLE
.: . . : . :
Mb2105|M.bovis_AF2122/97 EARRRFEASWNRENGEHPINDSAEVQRVTAALGVQSLQLPKIGVDLENIA
Rv2079|M.tuberculosis_H37Rv EARRRFEASWNRENGEHPINDSAEVQRVTAALGVQSLQLPKIGVDLENIA
MMAR_5468|M.marinum_M QARRRFETSWNRENGAHPINDSPQVQGLTTSLRSQAARLPEIGLQLDNIA
MUL_5057|M.ulcerans_Agy99 QARRRFETSWNRENGAHPINDSPQVQGLTTSLRSQAARLPEIGLQLDNIA
MAV_5292|M.avium_104 AARGRFEASWNHRNGALPINDSAEVQRVTRALAVEGRQLPRIATDLETIA
TH_2235|M.thermoresistible__bu EQRRAVAHLREAWEGQAASAALARAERNLDNQEALRARLSAMQQALASGG
Mvan_0049|M.vanbaalenii_PYR-1 GQRESLSHLQEHWSGQAASAALARGLDDIARQDRVAGRLLNLESALRNGG
MSMEG_6381|M.smegmatis_MC2_155 LISR--LPGWDSPAADAARGRIGTAKANVLDDAAVIGAVAQLADETAAAV
: . . : :
Mb2105|M.bovis_AF2122/97 ADLAEAQRAAAGRIATLESQLQRIDDQLDQALELEHDPRLAAAERSELDA
Rv2079|M.tuberculosis_H37Rv ADLAEAQRAAAGRIATLESQLQRIDDQLDQALELEHDPRLAAAERSELDA
MMAR_5468|M.marinum_M GGLAGAQRSATGQIVGLEAQLRDIDSEIGEVLALEHGAQLTTADRLALEA
MUL_5057|M.ulcerans_Agy99 GGLAGAQRSATGQIVGLETQLCDIDSEIGEVLALEHGAQLTTADRLALEA
MAV_5292|M.avium_104 AVLAESQRTSTWYIEALEYDLAAIDDEIGQALEEAD------------HC
TH_2235|M.thermoresistible__bu AQLTSTRDRLLRLVGMLRSTGWRIADDGTATAPP-------------VPP
Mvan_0049|M.vanbaalenii_PYR-1 LQMGALRDALLDLVSSLERFGFAVADDGTVTPEQWL-----------VGQ
MSMEG_6381|M.smegmatis_MC2_155 AKLQSQLEAVRADVAAQGGLLHLADNGDVTIGGSPDD-----------RE
: : .
Mb2105|M.bovis_AF2122/97 LITCLEQDAIDDTASALGQLQSIRAGYSDHLQQSLAMLRADGYDGAGLQG
Rv2079|M.tuberculosis_H37Rv LITCLEQDAIDDTASALGQLQSIRAGYSDHLQQSLAMLRADGYDGAGLQG
MMAR_5468|M.marinum_M LVCALEDQAVGGTQSAVSQLHSIRAGYAGLLHQALTSLSADGFDPAAIQA
MUL_5057|M.ulcerans_Agy99 IVCALEDQAVGDTQSAVSQLHSIRAGYAGLLHQAPTSLSADGFDPAVIQA
MAV_5292|M.avium_104 AAEELRYSAVTETKAITLVLEQIRESYSRLLHSALARLQADGVDPANVRG
TH_2235|M.thermoresistible__bu ILKLFAPAWTAVIKKLLAVFTEIDTQTAAAVREAASGPVPA--TPPGTLG
Mvan_0049|M.vanbaalenii_PYR-1 FLDSLADKFTGFLQKMLQLFTDLDENTAAAIDQAAGVDSPN--PPVEVGG
MSMEG_6381|M.smegmatis_MC2_155 QLKHIAENIEARAKALIHQAEDIDADCAEVFGHIENGDVTARGSSDFASA
: .: : . . .
Mb2105|M.bovis_AF2122/97 LDAPQSPVKLEEPIQIPPPGTGAPEVHRWWTSLTSEERQRLIAEHPEQIG
Rv2079|M.tuberculosis_H37Rv LDAPQSPVKPEEPIQIPPPGTGAPEVHRWWTSLTSEERQRLIAEHPEQIG
MMAR_5468|M.marinum_M LDAPQSPAEPAEVIAIPAPTASAEEVKKWWDSLSPQRRGRLIDEHPPELG
MUL_5057|M.ulcerans_Agy99 LDAPQSPAEPAEVIAIAAPTASAEEVKKWWDSLSPQQRGRLIDEHPPELG
MAV_5292|M.avium_104 VDELS----------IPPADTGPEQVKWWWDSLSAAQQRLLIDQHPQELG
TH_2235|M.thermoresistible__bu D-----------ARQLPAGDTDPDDVKEWWDSLSQAERDGLIAAHPPELG
Mvan_0049|M.vanbaalenii_PYR-1 Q-----------DIHIPSPDTDPADVKQWWDSLSEQQRRELIDRHPPMLG
MSMEG_6381|M.smegmatis_MC2_155 QEMGREQSGLSAPYPPEGEGVSPENVNAWWNALSEEEQAKVISEHPDWIG
... :*: ** :*: .: :* ** :*
Mb2105|M.bovis_AF2122/97 NLNGVPVSARSDANIAVMTRDLNRVRDIATRYRTSVD------------D
Rv2079|M.tuberculosis_H37Rv NLNGVPVSARSDANIAVMTRDLNRVRDIATRYRTSVD------------D
MMAR_5468|M.marinum_M NLNGINAITRDLVNQAVMDDDITRVESVAMQRGVSAD------------D
MUL_5057|M.ulcerans_Agy99 NLNGINAITRDLVNQAVMDDDITRVESVAMQRGVSAD------------D
MAV_5292|M.avium_104 NLNGIPAEARDSVNRATMTDDLSKVEAVARVRGVSVQALRDNALHNRDID
TH_2235|M.thermoresistible__bu NLNGIPAEVRGEVNEKVMNDDLDRVRDAAEEHGVSVD------------Q
Mvan_0049|M.vanbaalenii_PYR-1 NLNGIPAEVRDQVNVAVMDDDLDRVQNVADRNGVSTD------------E
MSMEG_6381|M.smegmatis_MC2_155 NRDGVPVAVRSEVNKAALDRELAEAQAAVDAMPSRDE-------------
* :*: . .*. .* .: :: ... . :
Mb2105|M.bovis_AF2122/97 VLGDPAKYGLSAGDITRYRNADETKKGLDHNA--------------RNDP
Rv2079|M.tuberculosis_H37Rv VLGDPAKYGLSAGDITRYRNADETKKGLDHNA--------------RNDP
MMAR_5468|M.marinum_M IVNNPRKYGLSGSDVTRYRNAIRTRDGLIYDR--------------EHAT
MUL_5057|M.ulcerans_Agy99 IVNNPQKYGLSASDVTRYRNAIRTRDGLIYDR--------------EHAT
MAV_5292|M.avium_104 MFRNPAAYGLCATDIVRYQNAVKTNDCLN------------------KAC
TH_2235|M.thermoresistible__bu VLENPAAYGLSATDAARYHNAEQTRKGLAQAR--------------DEDI
Mvan_0049|M.vanbaalenii_PYR-1 VAGNPGRYGLTDGDVTRYQNAKRTQEGLLHQLGAQDGETRRYSEIGEQER
MSMEG_6381|M.smegmatis_MC2_155 FRREHPGWNGAQLNAAYNKMMFERQGRLDDAKAMK-----------DALS
. : :. : . : . . *
Mb2105|M.bovis_AF2122/97 RNP--SPVYLFAYDPMAFGGKGRAAIAIGNPDTAKHTAVIVP--GTSSSV
Rv2079|M.tuberculosis_H37Rv RNP--SPVYLFAYDPMAFGGKGRAAIAIGNPDTAKHTAVIVP--GTSSSV
MMAR_5468|M.marinum_M DDP--RPVMLWAYDPLAFNGEGKAAIAIGNPDYARNTAVVVP--GTGSSV
MUL_5057|M.ulcerans_Agy99 DDP--RPVMLWAYDPLAFNGEGKAAIAIGNPDYARNTAVIVP--GAGSSV
MAV_5292|M.avium_104 DPG--LPLMLWAYDPLAFAGKGRAGIAIGNPDKSRNTAVVVP--GTNSSV
TH_2235|M.thermoresistible__bu RN---RPVLLWAYEPLAFDGQGKAALAIGDPDKAQNTAVVVP--GTGSSV
Mvan_0049|M.vanbaalenii_PYR-1 RDKNWRPTMLWAYDPQAFDGKGRAAVSIGNPDRASNTAVIVP--GTSASV
MSMEG_6381|M.smegmatis_MC2_155 VDGKYDPNKYLMLLEFPEDREPRAAIAVGNPDTAEHVTVTTPGVGTRPES
* . : :*.:::*:** : :.:* .* *: ..
Mb2105|M.bovis_AF2122/97 KGGWLHDNHDDALNLFNQAKAADPNNP-TAVIAWMGYDAPNDFTD-----
Rv2079|M.tuberculosis_H37Rv KGGWLHDNHDDALNLFNQAKAADPNNP-TAVIAWMGYDAPNDFTD-----
MMAR_5468|M.marinum_M AQGWMSD-HDDATNLYDQALAADPEHHYTAVIAWMGYDAPNGFSD-----
MUL_5057|M.ulcerans_Agy99 AQGWMSD-HDDATNLYDQALAADPEHHYTAVIAWMGYDAPNGFSD-----
MAV_5292|M.avium_104 RGGWMSDGADDAINLYTQAQRADPHHA-TAVLAWMGYDAP-EFDDSHWEQ
TH_2235|M.thermoresistible__bu EQGWLES--SNAVDLYDQMRKADPDET-TSVIAWMGYDAPDSPID-----
Mvan_0049|M.vanbaalenii_PYR-1 RDGWLSDGHNDAIHLYGQSLKADPADP-TAVISWMGYNTPESFTD-----
MSMEG_6381|M.smegmatis_MC2_155 LGGMVSEADALRQEAQTQLDRAGRSGEQVATIAWLGYEPPGTDIS-----
* : . . * *. .:.::*:**:.* .
Mb2105|M.bovis_AF2122/97 --------PRIATPMLARIGGAALAEDVNGLWVTHLGVG-QNVTVLGHSY
Rv2079|M.tuberculosis_H37Rv --------PRIATPMLARIGGAALAEDVNGLWVTHLGVG-QNVTVLGHSY
MMAR_5468|M.marinum_M --------VRVTEPGLARSGGALLANDVNGLWVTHNSLTPQHVTVIGHSY
MUL_5057|M.ulcerans_Agy99 --------VRVTEPGLARSGGALLANDVNGLWVTHNSLTPQHVTVIGHSY
MAV_5292|M.avium_104 AVTDPAKLEQVGTPWRARQAGVLLAGDVNGLAATHDAGSRAHVTVIGHSY
TH_2235|M.thermoresistible__bu --------RRIATPWLARHGGDLLAADVNGLAATHEGG-PSNVTVIGHSY
Mvan_0049|M.vanbaalenii_PYR-1 --------PNIANTGLARAGGDALAWDVNGLNVTHEAGVPEHVTVIGHSY
MSMEG_6381|M.smegmatis_MC2_155 -------VAEAGFERRANEAAPDLADFYRGINATNEHGSDVHLSAFGHSY
. *. .. ** .*: .*: :::.:****
Mb2105|M.bovis_AF2122/97 GSTTVADAFALGGMH--ANDAVLLGCPGTDLAHSAASFHLD-GGRVYVGA
Rv2079|M.tuberculosis_H37Rv GSTTVADAFALGGMH--ANDAVLLGCPGTDLAHSAASFHLD-GGRVYVGA
MMAR_5468|M.marinum_M GSTTVADAFAGSGMH--ANDAILIGCPGTDLARSAADFHLD-GGQVYVGS
MUL_5057|M.ulcerans_Agy99 GSTTVADAFAGSGMQ--ANDAILIGCPGTDLARSAADFHFD-GGQVYVGS
MAV_5292|M.avium_104 GSTTVADAFANSGMR--ANDAVLTGCPGTDLAHSAADFHLD-GGRLYVGA
TH_2235|M.thermoresistible__bu GSTTVANAFAGSGMQ--ADNAVLIGSPGTDLARSAADFNLPEGGNVYVGA
Mvan_0049|M.vanbaalenii_PYR-1 GSTTVADAFANSGMQ--ADDAILLGSPGTDVARSAADFNLD-GGQVYIGD
MSMEG_6381|M.smegmatis_MC2_155 GSLTTAQALYELGETGVVDDAAFYGSPGLGHTDSTETYISPRGVPIEVMA
** *.*:*: * .::* : *.** . : *: : * : :
Mb2105|M.bovis_AF2122/97 ASTDPISMLGQLDSLSQYVNRGNL--AGQLQGLAVGLGTDPAGDGFGSVR
Rv2079|M.tuberculosis_H37Rv ASTDPISMLGQLDSLSQYVNRGNL--AGQLQGLAVGLGTDPAGDGFGSVR
MMAR_5468|M.marinum_M ASTDPVSWIGESSGVPGELLKGKLREYGVPIPLDAGLGRDPAGDGFGSVR
MUL_5057|M.ulcerans_Agy99 ASTDPVSWIGESSGVPGELLKGKLREYGVPIPLDAGLGRDPAGDGFGSVR
MAV_5292|M.avium_104 ASTDAISWIGESGSGLPNGLNETL---GGPLGPFAGLGTDPAHAGFGAAR
TH_2235|M.thermoresistible__bu ASSDPVTWLGQGG-IAPDLINSQL---GFPLGPAAGLGTDPAGDSYGGMR
Mvan_0049|M.vanbaalenii_PYR-1 ASTDPVGWLGQMGNTLPGELNDSL---GNMVGPTAGLGADPAFEDFGATR
MSMEG_6381|M.smegmatis_MC2_155 PIRDESDMFLADGRAFVMSAPGDP------------ISGDPTWN--GVPL
. * : . :. **: *
Mb2105|M.bovis_AF2122/97 FRAEVPNSDGINP--HDHSYYYHRGSEALRSMADIASGHGDALASDGMLA
Rv2079|M.tuberculosis_H37Rv FRAEVPNSDGINP--HDHSYYYHRGSEALRSMADIASGHGDALASDGMLA
MMAR_5468|M.marinum_M FHAEVPGSATMDR--HDHSHYYVMGSESLRSITDIASGHPDRLASDDLIA
MUL_5057|M.ulcerans_Agy99 FHAEVPGSGTMDR--HDHSHYYVMGSESLRSITDISSGHPDRLASDDLIA
MAV_5292|M.avium_104 FRAEVAGSHSVMPWFTDHSDYYDVGSEALHNMTEIVTGRGNELAAEGMLA
TH_2235|M.thermoresistible__bu FTAEVPGRTGPSF--GDHSSYYTPGSESLRAITDIATGDAAKLADNGMIA
Mvan_0049|M.vanbaalenii_PYR-1 FRAEVPGADMIDP--SDHSYYYTVGSESLRSMTEIVTGNGGRLDELGLLA
MSMEG_6381|M.smegmatis_MC2_155 PSAGDLGQFGPNP-----------LTLPLEQLSADAAVTPDGVSREGAVA
* . : .*. :: : : . :*
Mb2105|M.bovis_AF2122/97 QPRHQPGVEID---------IPGLGSVEIDIP----GTPASIDPEWSRPP
Rv2079|M.tuberculosis_H37Rv QPRHQPGVEID---------IPGLGSVEIDIP----GTPASIDPEWSRPP
MMAR_5468|M.marinum_M EGRRQP----------------HVG--PFRVP----GVPAYIDPESDRPR
MUL_5057|M.ulcerans_Agy99 EGRRQP----------------HVG--PLRVP----GVPAYIDPESDRPR
MAV_5292|M.avium_104 PDRNAARVSILG--------RVHTPLGTLSLPRVEIRMPVVVDPEWERPA
TH_2235|M.thermoresistible__bu EGRKQAHIGLPDGLNTP-FGRIDLPDWEIRIPG----TPAYNDPEGDRAQ
Mvan_0049|M.vanbaalenii_PYR-1 QPRTELTVSTPQQLDVPVLGEVPLPHLEVETP-------VIYDPEWNRAG
MSMEG_6381|M.smegmatis_MC2_155 HADYPRPVELP------------SGEKVLRTPAYN---LAVIAAGLADVP
. * . .
Mb2105|M.bovis_AF2122/97 GSITDDHVFDAPLHR-
Rv2079|M.tuberculosis_H37Rv GSITDDHVFDAPLHR-
MMAR_5468|M.marinum_M DTVHDDHHYPAYQPPR
MUL_5057|M.ulcerans_Agy99 DTVHDDHHYPAYQPPR
MAV_5292|M.avium_104 RSVTNEHGF-------
TH_2235|M.thermoresistible__bu ESITSDHNY-------
Mvan_0049|M.vanbaalenii_PYR-1 GSVTNDHGY-------
MSMEG_6381|M.smegmatis_MC2_155 GPNGEDRLVR------
. .::