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MVEITQVSDAVHVVNGEAVNWVIASDDSGVTLFDSGYPGDRDDVLKSIAALGHKPQDVRAVVLTHGHIDH MGTAIWWAAEHGVPVYAHNAELGNVRRDYVDQAEPLKVVLNLWRPGWLPWVIHAMRLGAGVRDGIPTAAP LGPELADLPGAPAPIPTPGHSGGHCSFLVAGHVLVVGDAIITGHPVAKRSGPQLLPTPFTKDMEQARRSA EALADVDADVLAPGHGPAWIGSLRDAVQIALNT
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_4231 | - | - | 100% (243) | Beta-lactamase-like protein |
M. abscessus ATCC 19977 | MAB_1114 | - | 5e-14 | 29.85% (201) | metallo-beta-lactamase superfamily |
M. abscessus ATCC 19977 | MAB_2873c | - | 4e-05 | 29.83% (181) | hypothetical protein MAB_2873c |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0414c | - | 2e-71 | 52.48% (242) | beta lactamase like protein |
M. gilvum PYR-GCK | Mflv_0212 | - | 3e-72 | 53.85% (234) | beta-lactamase domain-containing protein |
M. tuberculosis H37Rv | Rv0406c | - | 2e-71 | 52.48% (242) | beta lactamase like protein |
M. leprae Br4923 | MLBr_00270 | - | 1e-72 | 51.48% (237) | hypothetical protein MLBr_00270 |
M. marinum M | MMAR_0708 | - | 6e-73 | 54.39% (239) | beta lactamase-like protein |
M. avium 104 | MAV_4762 | - | 5e-79 | 54.55% (242) | metallo-beta-lactamase superfamily protein |
M. smegmatis MC2 155 | MSMEG_0775 | - | 5e-68 | 48.76% (242) | metallo-beta-lactamase superfamily protein |
M. thermoresistible (build 8) | TH_2303 | - | 8e-72 | 51.67% (240) | BETA LACTAMASE LIKE PROTEIN |
M. ulcerans Agy99 | MUL_2815 | - | 4e-73 | 54.39% (239) | beta lactamase-like protein |
M. vanbaalenii PYR-1 | Mvan_0697 | - | 3e-73 | 52.77% (235) | beta-lactamase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment MLBr_00270|M.leprae_Br4923 ------------------MAAATLFQVTDSVHFARGDAVNWALVADDTGV MAV_4762|M.avium_104 --------------------MAELVQVTDAVHLARGDAVNWTLVADDTGV Mb0414c|M.bovis_AF2122/97 MVATRGTRLAALALAPRLAGMAELVQITDKVHLARGHAVNWVLVTDDTGV Rv0406c|M.tuberculosis_H37Rv MVATRGTRLAALALAPRLAGMAELVQITDKVHLARGHAVNWVLVTDDTGV MMAR_0708|M.marinum_M MPHQR----------------TELVQVTDKVHLAQGPAVNWVLVTDETGV MUL_2815|M.ulcerans_Agy99 MPHQR----------------TELVQVTDKVHLAQGPAVNWVLVTDETGV Mflv_0212|M.gilvum_PYR-GCK -------------------MAPVVTAVTDRVHFVRTELVNWTLVRDDDGV Mvan_0697|M.vanbaalenii_PYR-1 -------------------MALALTAITDRVHFAQTDLVNWTLVAEDGGV MSMEG_0775|M.smegmatis_MC2_155 -------------------MAVALNKITDRVHFARTELVNWTLVTGDDGV TH_2303|M.thermoresistible__bu ----------------MAAPAVRLEQITDSVHFANTDLVNWVLVTDGTGV MAB_4231|M.abscessus_ATCC_1997 --------------------MVEITQVSDAVHVVNGEAVNWVIASDDSGV : ::* **... ***.:. ** MLBr_00270|M.leprae_Br4923 MLIDTGYPGDRDDVVASLRQLGYEAGDVRAILLTHAHIDHMGSAIWFASK MAV_4762|M.avium_104 MLVDAGYPGDREDVLGSLAELGYGPGDVRAIVLTHAHIDHLGTAIWLASE Mb0414c|M.bovis_AF2122/97 LLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHAHIDHLGSAIWFARE Rv0406c|M.tuberculosis_H37Rv LLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHAHIDHLGSAIWFARE MMAR_0708|M.marinum_M MLIDAGYPGDRNNVLTSLRTLGYGPGDVRAILLTHAHIDHLGTAIWFAAQ MUL_2815|M.ulcerans_Agy99 MLIDAGYPGDRNNVLTSLRTLGYGPGDVRAILLTHAHIDHLGTAIWFAAQ Mflv_0212|M.gilvum_PYR-GCK ILIDAGFPGHRDEVLTSLHGLGFGVGDVRAILLTHAHIDHFGTAIWFAAT Mvan_0697|M.vanbaalenii_PYR-1 LLIDAGYPGHREEVLESLGRLGFGATDVRAILLTHAHIDHFGSAMWFARE MSMEG_0775|M.smegmatis_MC2_155 LLIDAGFPGQREDVLDSVRQLGFGPDDIKAVLLTHAHVDHFGTAIWLAKT TH_2303|M.thermoresistible__bu VLIDAGYPGQRGLVLHSLRQLGFGPDAVRAILLTHAHIDHLGSAIWFAKT MAB_4231|M.abscessus_ATCC_1997 TLFDSGYPGDRDDVLKSIAALGHKPQDVRAVVLTHGHIDHMGTAIWWAAE *.*:*:**.* *: *: **. ::*::***.*:**:*:*:* * MLBr_00270|M.leprae_Br4923 HRTPVYCHADEVGHTKREYLEQVSLLNIAMRVWQPRWAIWSGHVLRSGGL MAV_4762|M.avium_104 HGIPVYCHADEVGHAKREYLEQVSIVDVALRIWRPRWAKWTAHVVRSGGL Mb0414c|M.bovis_AF2122/97 HSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLRRGGL Rv0406c|M.tuberculosis_H37Rv HSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLRRGGL MMAR_0708|M.marinum_M HGTPVYCDANEVGHAKREYHESASPLDVVLRSWRPRTALWGIHLVFRGGL MUL_2815|M.ulcerans_Agy99 HGTPVYCDANEVGHAKREYHESASPLDVVLRSWRPRTALWGIHLVFRGGL Mflv_0212|M.gilvum_PYR-GCK HGTPVYCHADEVAHSRRDHLEQASPIDIAKHAWQPTWLKWSVSIIGKGAL Mvan_0697|M.vanbaalenii_PYR-1 HGTPVYCHADEVGHAKREYLEQASPLAVAAHAWQPRWLKWSLTLIRKGGL MSMEG_0775|M.smegmatis_MC2_155 YGTPVYCHADEVGHARREYLEQATPAGVARQAWQPRWLKWALAISRQGAF TH_2303|M.thermoresistible__bu HGTPVFCHADEVGHAKRAYLEQVSPLDLAGQLWRPRWLTWSLTAVRTGAL MAB_4231|M.abscessus_ATCC_1997 HGVPVYAHNAELGNVRRDYVDQAEPLKVVLNLWRPGWLPWVIHAMRLGAG : **:.. *:.: :* : :.. :. . *:* * *. MLBr_00270|M.leprae_Br4923 IRGGIPTAQPLTAETAAGLPGHPMAIFTPGHTGGHCSYVVDG-VLISGDA MAV_4762|M.avium_104 IRDGIPTAQPLTAEVAAGLPGRPTPVFSPGHTNGHCSYLIDG-VLVSGDA Mb0414c|M.bovis_AF2122/97 TGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDG-VLASGDA Rv0406c|M.tuberculosis_H37Rv TGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDG-VLASGDA MMAR_0708|M.marinum_M RRAGVPSTQALSAEVAAALPGHPIPIPTPGHTSGHCSYLVDG-VLASGDA MUL_2815|M.ulcerans_Agy99 RRAGVPSTQALSAEVAAALPGHPIPIPTPGHTSGHCSYLVDG-VLASGDA Mflv_0212|M.gilvum_PYR-GCK TRAGIASTAPLTDHIAAALPGSPVCIPTPGHTGGHCSYVVDG-VLVSGDA Mvan_0697|M.vanbaalenii_PYR-1 DRTGIPTTAALSEDIAAGLPGAPVCVPTPGHTGGHCSYVVDG-VLVSGDA MSMEG_0775|M.smegmatis_MC2_155 DHSGIPSTQAFTPEIG--LPGNPTAIPTPGHTGGHCSYLVDG-VLVAGDA TH_2303|M.thermoresistible__bu VREGIPGTRALTEDVAAQLPGQPVVIPSPGHTAGHCSYLIGE-VLVSGDA MAB_4231|M.abscessus_ATCC_1997 VRDGIPTAAPLGPELAD-LPGAPAPIPTPGHSGGHCSFLVAGHVLVVGDA *:. : .: . . *** * : :***: ****::: ** *** MLBr_00270|M.leprae_Br4923 LITGHPLLRHRGPQLLTAVFSHSQKQCLRSLDALGLLETRILAPGHGELW MAV_4762|M.avium_104 LITGHPLLRHRGPQLLPAIFSYSQRDCIRTLSALALLDTEVLLPGHGDVW Mb0414c|M.bovis_AF2122/97 LITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELW Rv0406c|M.tuberculosis_H37Rv LITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELW MMAR_0708|M.marinum_M LITGHPMLRHRGPQLLPAVFSKVQERCIRSLSTLAQVEADTLAPGHGSLW MUL_2815|M.ulcerans_Agy99 LITGHPMLRHRGPQLLPAVFSKVQERCIRSLSTLAQVEADTLAPGHGSLW Mflv_0212|M.gilvum_PYR-GCK LITGHPVASRRGPQLLPSVFNHDEDACRRSLTTLGALDTEVILPGHGPLW Mvan_0697|M.vanbaalenii_PYR-1 LITGHPVSRRRGPQLLPSVFNHDEVACLRSLEALGMLDTEVMLPGHGPVW MSMEG_0775|M.smegmatis_MC2_155 LVTGHPTSSRRGPQLLHQVFNHDQQACLRSLGALGLLDTEVLLPGHGDVW TH_2303|M.thermoresistible__bu LVTGHPVAPRRGPQLLPEVFNHDQDSCVRSVAALGLLDAEVLLPGHGPVW MAB_4231|M.abscessus_ATCC_1997 IITGHPVAKRSGPQLLPTPFTKDMEQARRSAEALADVDADVLAPGHGPAW ::**** : ***** *. . *: :*. ::: : **** * MLBr_00270|M.leprae_Br4923 HGPIREATEAALKQAGALTR--- MAV_4762|M.avium_104 RGPIKEATDAALALATGR----- Mb0414c|M.bovis_AF2122/97 HGPIRKATDEALERAQKSNHVFR Rv0406c|M.tuberculosis_H37Rv HGPIRKATDEALERAQKSNHVFR MMAR_0708|M.marinum_M RGPIRLATEEARARAQR------ MUL_2815|M.ulcerans_Agy99 RGPIRLATEEARARAQR------ Mflv_0212|M.gilvum_PYR-GCK RGPVRDAAAQAAQASVR------ Mvan_0697|M.vanbaalenii_PYR-1 RGPVRDAVAQATTAEP------- MSMEG_0775|M.smegmatis_MC2_155 RGSIREMADQAASSAPSPAR--- TH_2303|M.thermoresistible__bu RGEISTAARLATPA--------- MAB_4231|M.abscessus_ATCC_1997 IGSLRDAVQIALNT--------- * : . *