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M. avium 104 MAV_4541 (-)

annotation: cyclopropane-fatty-acyl-phospholipid synthase 1
coordinates: 4666888 - 4667754
length: 288

VAENLTPHFEEVQAHYDLSDDFFRLFLDPTMTYSCAYWDRNRDISLEEAQLRKIDLSLGKLGLRPGMTLL
DVGCGWGATMRRAVENYDVNVIGLTLSRHQAAHVQQLLDAMDTPRSRRVLLHGWEEFDEPVDRIVSIGAF
EHFGYDRYDDFFATAYRVLPDDGVMLLHTITMLTPEQIVERGLPLTEEQTSFNEFIATEIFPGGQLPAIE
VVEFHSSKMGFTLKRRQSLQLHYARTLDHWADALRAHHSEAVAIQSEEVYQRYMRYLTGCADAFRAGYID
VNQFTLAK
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_4541--100% (288)cyclopropane-fatty-acyl-phospholipid synthase 1
M. avium 104MAV_0130-e-11368.29% (287) cyclopropane-fatty-acyl-phospholipid synthase 1
M. avium 104MAV_4679-e-11067.96% (284) cyclopropane-fatty-acyl-phospholipid synthase 1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0663cmmaA21e-12473.96% (288) methoxy mycolic acid synthase
M. gilvum PYR-GCKMflv_3304-1e-11267.37% (285) cyclopropane-fatty-acyl-phospholipid synthase
M. tuberculosis H37RvRv0644cmmaA21e-12574.31% (288) methoxy mycolic acid synthase
M. leprae Br4923MLBr_02459umaA21e-11168.31% (284) Mycolic acid synthase
M. abscessus ATCC 19977MAB_3881-1e-10162.32% (284) cyclopropane-fatty-acyl-phospholipid synthase 1
M. marinum MMMAR_0979mmaA5_11e-12674.31% (288) methoxy mycolic acid synthase 5 MmaA5_1
M. smegmatis MC2 155MSMEG_1351-1e-12172.89% (284) cyclopropane-fatty-acyl-phospholipid synthase 1
M. thermoresistible (build 8)TH_4640-1e-12273.17% (287) PUTATIVE methoxy mycolic acid synthase 5 MmaA5_1
M. ulcerans Agy99MUL_3772mmaA51e-12171.53% (288) methoxy mycolic acid synthase 5 MmaA5
M. vanbaalenii PYR-1Mvan_3025-1e-11268.42% (285) cyclopropane-fatty-acyl-phospholipid synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3304|M.gilvum_PYR-GCK          MSDTPNGSADLQPHFDDVQSHYDLSDDFYRLFLDPTQTYSCAYFERD-DM
Mvan_3025|M.vanbaalenii_PYR-1       MPETTSGSADLQPHFEDVQSHYDLSDDFYRLFLDPTQTYSCAYFERD-DM
MLBr_02459|M.leprae_Br4923          ------MSVQLTPHFRNVQAHYDLSDDFFRLFLDPTLTYSCAYFERD-DM
Mb0663c|M.bovis_AF2122/97           ------MVNDLTPHFEDVQAHYDLSDDFFRLFLDPTQTYSCAHFERE-DM
Rv0644c|M.tuberculosis_H37Rv        ------MVNDLTPHFEDVQAHYDLSDDFFRLFLDPTQTYSCAHFERE-DM
MUL_3772|M.ulcerans_Agy99           ------MAKHLAPRFDDVQAHYDLSDDFFRLFLDPTQTYSCAYFERD-DM
MMAR_0979|M.marinum_M               ------MAKELKPHFDDVQAHYDLSDDFFRLFLDPTQTYSCAYFERD-DM
TH_4640|M.thermoresistible__bu      ---MAEPAKKLKPHFADVQAHYDLSDEFFGLFLDPTRTYSCAYFERD-DM
MAV_4541|M.avium_104                ------MAENLTPHFEEVQAHYDLSDDFFRLFLDPTMTYSCAYWDRNRDI
MSMEG_1351|M.smegmatis_MC2_155      ---MTKQPGKLQPHFDEVQAHYDLSDDFFALFLDPSRTYSCAYFERD-DM
MAB_3881|M.abscessus_ATCC_1997      -------MSKLTPKFSDVQAHYDLSDDFFALFLDPSRTYSCAYFEPE-TL
                                             .* *:* :**:******:*: *****: *****::: :  :

Mflv_3304|M.gilvum_PYR-GCK          TLEEAQRAKIDLALGKLGLEPGMTLLDIGCGWGGTLLRALEKYDVNVIGL
Mvan_3025|M.vanbaalenii_PYR-1       TLEEAQIAKIDLSLGKLGLQPGMTLLDIGCGWGATLLRALDKYDVNVIGL
MLBr_02459|M.leprae_Br4923          TLEEAQLAKVDLALGKLKLEPGMTLLDIGCGWGATMKRAIEIYDVNVIGL
Mb0663c|M.bovis_AF2122/97           TLEEAQIAKIDLALGKLGLQPGMTLLDIGCGWGATMRRAIAQYDVNVVGL
Rv0644c|M.tuberculosis_H37Rv        TLEEAQIAKIDLALGKLGLQPGMTLLDIGCGWGATMRRAIAQYDVNVVGL
MUL_3772|M.ulcerans_Agy99           TLEEAQIAKIDLALGKLGLEPGMTLLDIGCGWGATMRRAIEKYDVNVVGL
MMAR_0979|M.marinum_M               TLEEAQIAKIDLALGKLGLEPGMTLLDVGCGWGATMRRAIEKYDVNVVGL
TH_4640|M.thermoresistible__bu      SLEEAQLAKIDLALGKLGLQPGMTLLDIGCGWGSTMLRALERHDVDVVGL
MAV_4541|M.avium_104                SLEEAQLRKIDLSLGKLGLRPGMTLLDVGCGWGATMRRAVENYDVNVIGL
MSMEG_1351|M.smegmatis_MC2_155      TLEEAQLAKIDLSLGKLGLQPGMTLLDVGCGWGATMLRALERYDVNVVGL
MAB_3881|M.abscessus_ATCC_1997      TLEQAQQAKIDLALGKLNLEPGMTLLDVGCGWGSTMKRALEHYDVNVIGL
                                    :**:**  *:**:**** *.*******:*****.*: **:  :**:*:**

Mflv_3304|M.gilvum_PYR-GCK          TLSRNQQAHVQKVLDEHDSPRSKTVLLQGWEQFDQPVDRIVSIGAFEHFG
Mvan_3025|M.vanbaalenii_PYR-1       TLSRNQQAHVQKRLDAHGSGRSKRVLLAGWEQFDEPVDRIVSIGAFEHFG
MLBr_02459|M.leprae_Br4923          TLSENQAAHVQKTFDELDTPRTRRVLLEGWEKFHEPVDRIVSIGAFEHFG
Mb0663c|M.bovis_AF2122/97           TLSKNQAAHVQKSFDEMDTPLDRRVLLAGWEQFNEPVDRIVSIGAFEHFG
Rv0644c|M.tuberculosis_H37Rv        TLSKNQAAHVQKSFDEMDTPRDRRVLLAGWEQFNEPVDRIVSIGAFEHFG
MUL_3772|M.ulcerans_Agy99           TLSKNQAAHVQKSFDQLDTARTRRVLLEGWEQFDEPVDRIVSIGAFEHFG
MMAR_0979|M.marinum_M               TLSKNQAAHVQKSFDQLDTARTRRVLLEGWEQFDEPVDRIVSIGAFEHFG
TH_4640|M.thermoresistible__bu      TLSANQHAHVEQLLADSPSRRSRRVLLRGWEEFDEPVDRIVSIGAFEHFG
MAV_4541|M.avium_104                TLSRHQAAHVQQLLDAMDTPRSRRVLLHGWEEFDEPVDRIVSIGAFEHFG
MSMEG_1351|M.smegmatis_MC2_155      TLSRNQQAHVERRFSESSSPRTKRVLLAGWEEFDEPVDRIVSIGAFEHFG
MAB_3881|M.abscessus_ATCC_1997      TLSKNQFAYVNTLLDSAGSSRNYEVRLAGWEEFEGTVDRIVSIGAFEHFG
                                    *** :* *:*:  :    :     * * ***:*. .**************

Mflv_3304|M.gilvum_PYR-GCK          SDRYDEFFRRAYSVLPDDGVMLLHTIVKPSDEEFAERKLPLTMTKLKFFK
Mvan_3025|M.vanbaalenii_PYR-1       RDRYDEFFKKAYQVLPDGGVMMLHTIIKPTDEEFADRGLKLTMSIVRFSK
MLBr_02459|M.leprae_Br4923          RQRYARFFKMAHEVLPADSVMLLHTIVRPTFKDARARGMTLTHEIVHFTQ
Mb0663c|M.bovis_AF2122/97           HDRHADFFARAHKILPPDGVLLLHTITGLTRQQMVDHGLPLTLWLARFLK
Rv0644c|M.tuberculosis_H37Rv        HDRHADFFARAHKILPPDGVLLLHTITGLTRQQMVDHGLPLTLWLARFLK
MUL_3772|M.ulcerans_Agy99           HDRYDDFFTLAHNILPSDGVMLLHTITGLTMPQMVENGLPLTLWLARFLK
MMAR_0979|M.marinum_M               HDRYDDFFTLAHNILPSDGVMLLHTITGLTFQQATDRGMPLTFEIARFIK
TH_4640|M.thermoresistible__bu      HDRYDDFFATAHRLLPDDGVMLLHTITALTVPQMVDRGIPLTFEVARFVK
MAV_4541|M.avium_104                YDRYDDFFATAYRVLPDDGVMLLHTITMLTPEQIVERGLPLTEEQTSFNE
MSMEG_1351|M.smegmatis_MC2_155      HERYDDFFRFAHRVLPDDGVMLLHTITGIHPKHAQELGVPLTFEMARFIR
MAB_3881|M.abscessus_ATCC_1997      HERYDSFFAMAHRVLPSDGKMLLHTIVSHHPDEWKRMGIPLLMSRVRFIY
                                     :*:  **  *: :** .. ::****      .     : *      *  

Mflv_3304|M.gilvum_PYR-GCK          FIMDEIFPGGMLPKVDDVEKHATKASFKVNRIQPLRLHYARTLQIWAASL
Mvan_3025|M.vanbaalenii_PYR-1       FIMDEIFPGGDLPKPTTVAEHATKAGFRLTREQRLREHYAKTLDIWADAL
MLBr_02459|M.leprae_Br4923          FILAEIFPGGWLPTVPTVEEHATAAGFKFTRIQSLQLHYAKTLDLWAARL
Mb0663c|M.bovis_AF2122/97           FIATEIFPGGQPPTIEMVEEQSAKTGFTLTRRQSLQPHYARTLDLWAEAL
Rv0644c|M.tuberculosis_H37Rv        FIATEIFPGGQPPTIEMVEEQSAKTGFTLTRRQSLQPHYARTLDLWAEAL
MUL_3772|M.ulcerans_Agy99           FIQTEIFPGGHPPTIEMVEEQSVKPGFTLTRRHSLQLHYAKTLDLWAEAL
MMAR_0979|M.marinum_M               FIVTEIFPGGRLPSIEKVADHSSKAGFTLTRRQSLQPHYARTLDLWAQAL
TH_4640|M.thermoresistible__bu      FILTEIFPGGRLPSIEKVEDHSGANGFTLTRRQSLQSHYARTLDLWAEAL
MAV_4541|M.avium_104                FIATEIFPGGQLPAIEVVEFHSSKMGFTLKRRQSLQLHYARTLDHWADAL
MSMEG_1351|M.smegmatis_MC2_155      FIVTEIFPGGRLPTVDMVIDHATRASFTLERRQSLQLHYARTLDMWAAAL
MAB_3881|M.abscessus_ATCC_1997      FIGTEIFPGGRLPSVPMVDKHAALAGFHITRHHSLQPHYARTLDCWATNL
                                    **  ******  *    *  ::   .* . * : *: ***:**: **  *

Mflv_3304|M.gilvum_PYR-GCK          ESRRDDAIAIQSEEVYDRYMKYLTGCAELFTEGYTDVCQFTLAK------
Mvan_3025|M.vanbaalenii_PYR-1       RKREDDAVAIQSREDYDRYMKYLTGCADLFRDGYTDICQFTLEK------
MLBr_02459|M.leprae_Br4923          EANKNKAIAIQSEEVYDRYMKYLTGCAKLFRDGYTDVDQFTLEKQPATAR
Mb0663c|M.bovis_AF2122/97           QEHKSEAIAIQSEEVYERYMKYLTGCAKLFRVGYIDVNQFTLAK------
Rv0644c|M.tuberculosis_H37Rv        QEHKSEAIAIQSEEVYERYMKYLTGCAKLFRVGYIDVNQFTLAK------
MUL_3772|M.ulcerans_Agy99           EVRKDEAIKIQSDEVYERYMRYLTGCSKLFQEGYVDVNQFTLQKAR----
MMAR_0979|M.marinum_M               QARRDEAIEVQSEEVYERYMKYLTGCADGFRVGYIDVNQFTLEKS-----
TH_4640|M.thermoresistible__bu      QQHREEAITVQSDEVYDRYIKYLTGCAKGFRVGYIDVNQFTLQK------
MAV_4541|M.avium_104                RAHHSEAVAIQSEEVYQRYMRYLTGCADAFRAGYIDVNQFTLAK------
MSMEG_1351|M.smegmatis_MC2_155      ESHHDDAVRIQSQEVYDRYMHYLTGCANAFRVGYIDVNQFTLAK------
MAB_3881|M.abscessus_ATCC_1997      AAHEDEAISVQSQEVYDRYIKYLTGCAEGFREGWIDVVQFTCEK------
                                      ....*: :** * *:**::*****:. *  *: *: ***  *      

Mflv_3304|M.gilvum_PYR-GCK          --
Mvan_3025|M.vanbaalenii_PYR-1       --
MLBr_02459|M.leprae_Br4923          RH
Mb0663c|M.bovis_AF2122/97           --
Rv0644c|M.tuberculosis_H37Rv        --
MUL_3772|M.ulcerans_Agy99           --
MMAR_0979|M.marinum_M               --
TH_4640|M.thermoresistible__bu      --
MAV_4541|M.avium_104                --
MSMEG_1351|M.smegmatis_MC2_155      --
MAB_3881|M.abscessus_ATCC_1997      --