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M. avium 104 MAV_4418 (-)

annotation: acyl-CoA dehydrogenase family protein member 8
coordinates: 4553276 - 4554436
length: 386

MFTLDDDERVIAETAAAFAAKRLAPHALEWDAAEHFPVDVLRESAELGMAAIYCREDVGGSGLRRLDGVR
IFEQLAIADPTTAAFLSIHNMCAWMIDSYGTPEQRKGWVPRLAAMDVIASYCLTEPGAGSDAAALSTRAV
RQGGDYVLDGVKQFISGAGASDVYLVMARTGGEGPRGISAFVVEKGSAGLSFGSPEEKMGWHAQPTAQVI
LEGVRVPADAMLGGAEGEGAGFGIAMNGLNGGRLNIAACSLGGAQAAFDKAGAYVRDRQAFGSPLLDEPT
IRFALADMATGLETSRMMLWRAAGALDADDPDKVELCAMAKRYVTDTCFEVADKALQLHGGYGYLREYGL
EKIVRDLRVHRILEGTNEIMRVVIGRAEAARFRATA

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. avium 104 MAV_4418 - - 100% (386) acyl-CoA dehydrogenase family protein member 8
M. avium 104 MAV_2668 - 2e-65 38.54% (371) acyl-CoA dehydrogenase
M. avium 104 MAV_4243 - 1e-62 34.92% (378) acyl-CoA dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0774c fadE9 0.0 88.43% (389) acyl-CoA dehydrogenase FADE9
M. gilvum PYR-GCK Mflv_5011 - 0.0 81.51% (384) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv0752c fadE9 0.0 88.43% (389) acyl-CoA dehydrogenase FADE9
M. leprae Br4923 MLBr_00737 fadE25 2e-63 35.98% (378) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_1188c - 1e-134 62.23% (376) acyl-CoA dehydrogenase
M. marinum M MMAR_1078 fadE9 0.0 87.44% (390) acyl-CoA dehydrogenase, FadE9
M. smegmatis MC2 155 MSMEG_1497 - 1e-180 80.10% (392) acyl-CoA dehydrogenase family protein member 8
M. thermoresistible (build 8) TH_4417 - 0.0 81.72% (383) PUTATIVE acyl-CoA dehydrogenase domain protein
M. ulcerans Agy99 MUL_0836 fadE9 0.0 86.92% (390) acyl-CoA dehydrogenase, FadE9
M. vanbaalenii PYR-1 Mvan_1361 - 0.0 81.77% (384) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0774c|M.bovis_AF2122/97           -----------MFVLNDDERVIVETAAAFAGKRLAPHALEWDAAKHFPVD
Rv0752c|M.tuberculosis_H37Rv        -----------MFVLNDDERVIVETAAAFAGKRLAPHALEWDAAKHFPVD
MMAR_1078|M.marinum_M               -----------MFTLNDDERVITQTAAAFADKRLAPYALEWDATKHFPVD
MUL_0836|M.ulcerans_Agy99           -----------MFTLNDDERVITQTAAAFADKRLAPYALEWDATKHFPVD
MAV_4418|M.avium_104                -----------MFTLDDDERVIAETAAAFAAKRLAPHALEWDAAEHFPVD
Mflv_5011|M.gilvum_PYR-GCK          ---------MDYFGLDDDDRVIAETAAAFAEKRLAPHALEWDETHHFPVD
Mvan_1361|M.vanbaalenii_PYR-1       ---------MDYFGLDEDERVIAETAAAFAEKRLAPYALEWDETHHFPAD
TH_4417|M.thermoresistible__bu      ---------MDYLGLDDDERVIAETAAAFAEKRLAPYALEWDATKHFPTD
MSMEG_1497|M.smegmatis_MC2_155      ---------MYLSDLDDDERVIVETAAAFAEKRITPYALEWDDKHHFPTD
MAB_1188c|M.abscessus_ATCC_199      -----------MFNLTEEQREIWNTAREFADIHIAPHALDWDRDKYFPVE
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
                                                  * ::.. :  *   :*  .::*:* : *    ** :

Mb0774c|M.bovis_AF2122/97           VLREAAELGMAAIYCRDDVGGSGLRRLDGARIFEQLAIADPVTAAFLSIH
Rv0752c|M.tuberculosis_H37Rv        VLREAAELGMAAIYCRDDVGGSGLRRLDGVRIFEQLAIADPVTAAFLSIH
MMAR_1078|M.marinum_M               VLREAAELGMAAIYCREDVGGSGLRRLDGVRIFEQLAIADPVTAAFLSIH
MUL_0836|M.ulcerans_Agy99           VLREAAELGMAAIYCREDVGGSGLRRLDGVRIFEQLAIADPVTAAFLSIH
MAV_4418|M.avium_104                VLRESAELGMAAIYCREDVGGSGLRRLDGVRIFEQLAIADPTTAAFLSIH
Mflv_5011|M.gilvum_PYR-GCK          VLREAAELGMAAIYCGEDAGGSGLRRIDAVRIFEKLSTADPTVAAFLSIH
Mvan_1361|M.vanbaalenii_PYR-1       VLREAAELGMAAIYCRDDVGGSGLRRIDAVRIFEKLATADPTVAAFLSIH
TH_4417|M.thermoresistible__bu      ALREAAELGMAAIYCSEEVGGSGLRRLDAVRIFEHLSAADPTTAAFLSIH
MSMEG_1497|M.smegmatis_MC2_155      VLREAAELGMGAIYCREDVGGSELRRLDAVRIFEALSAADPTLAAFLSIH
MAB_1188c|M.abscessus_ATCC_199      IFPKAAALGMGGIYVNPDVGGSGLTRLDASLIFEAMATGCSAVSAFISIH
MLBr_00737|M.leprae_Br4923          ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
                                     :      *: .*:   : **.    : .  ::* ::   .  : : :::

Mb0774c|M.bovis_AF2122/97           NMCAWMIDSFGTDEQRKDWIPRLATMGVIASYCLTEPGAGSDAGALSTRA
Rv0752c|M.tuberculosis_H37Rv        NMCAWMIDSFGTDEQRKDWIPRLATMGVIASYCLTEPGAGSDAGALSTRA
MMAR_1078|M.marinum_M               NMCAWMIDSFGTDEQRKDWIPRLATMDAIASYCLTEPGAGSDASALSARA
MUL_0836|M.ulcerans_Agy99           NMCTWMIDSFGTDEQRKDWIPRLATMDAIASYCLTEPGAGSDASALSARA
MAV_4418|M.avium_104                NMCAWMIDSYGTPEQRKGWVPRLAAMDVIASYCLTEPGAGSDAAALSTRA
Mflv_5011|M.gilvum_PYR-GCK          NMCAWMVDSFGTEEQRKLWVPKLASMDAIASYCLTEPGAGSDASALRTKA
Mvan_1361|M.vanbaalenii_PYR-1       NMCAWMVDSFGTEEQRKEWVPRLASMDAIASYCLTEPGAGSDASALRTKA
TH_4417|M.thermoresistible__bu      NMCAWMVDTYGTDEQRKTWVPRLASMDAIASYCLTEPGAGSDAAALRTRA
MSMEG_1497|M.smegmatis_MC2_155      NMCAWMVDTYGTEDQRKTWVPRLASMETIASYCLTEPGAGSDAAALRTRA
MAB_1188c|M.abscessus_ATCC_199      NMAAWMIDEFGDEEQRRRWLPSMCTMETIGAYCLTEPECGSDAAALRTSA
MLBr_00737|M.leprae_Br4923          KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTRA
                                    :: :  :   *  : ::  :* :.:  .:.:*.*:*  .****.:: : *

Mb0774c|M.bovis_AF2122/97           VRHGSGKGGDYVLDGVKQFISGAAASDVYVVMARTGAE-GPRGVSAFVVE
Rv0752c|M.tuberculosis_H37Rv        VRHGSGKGGDYVLDGVKQFISGAAASDVYVVMARTGAE-GPRGVSAFIVE
MMAR_1078|M.marinum_M               VRQGSAPGSDYVLDGVKQFISGAGASDVYVVMARTGAE-GPRGISAFIVE
MUL_0836|M.ulcerans_Agy99           VRQGSAPGSDYVLDGVKQFISGAGASDVYVVMARTGAE-GPRGISAFIVE
MAV_4418|M.avium_104                VRQ----GGDYVLDGVKQFISGAGASDVYLVMARTGGE-GPRGISAFVVE
Mflv_5011|M.gilvum_PYR-GCK          VRS----GDEYVLDGVKQFISGAGTSDVYIVMARTGSD-GPKGISAFVVP
Mvan_1361|M.vanbaalenii_PYR-1       VRS----GDDYVLDGVKQFISGAGSSDVYVVMARTGSD-GPKGISAFVVP
TH_4417|M.thermoresistible__bu      VRD----GDHFVLDGVKQFISGAGASDVYVVMARTGED-GPKGISTFIVE
MSMEG_1497|M.smegmatis_MC2_155      VKD----GDHYVLDGVKQFISGAGTSDLYVVMARTGGE-GPRGISTFIVE
MAB_1188c|M.abscessus_ATCC_199      IRQ----GDEYVLNGVKQFISGAGAADLYVVMARTGGP-GPRGISTIVVP
MLBr_00737|M.leprae_Br4923          KAD----GDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVH
                                           *..::*:*.* :*:... :  * *** *.   *..*:*:::* 

Mb0774c|M.bovis_AF2122/97           KGTPGLSFGAPEAKMGWHAQPTAQVVLDGVRVPAEAMLGGADGEGAGFGI
Rv0752c|M.tuberculosis_H37Rv        KGTPGLSFGAPEAKMGWHAQPTAQVVLDGVRVPAEAMLGGADGEGAGFGI
MMAR_1078|M.marinum_M               KGTPGLSFGALEEKMGWHAQPTAQVVLEGVRVPADAMLGGVDGTGAGFGI
MUL_0836|M.ulcerans_Agy99           KGTPGLSFGALEEKMGWHAQPTAQVVLEGVRVPADAMLGGVDGTGAGFGI
MAV_4418|M.avium_104                KGSAGLSFGSPEEKMGWHAQPTAQVILEGVRVPADAMLGGAEGEGAGFGI
Mflv_5011|M.gilvum_PYR-GCK          KDTPGLSFGTDEVKMGWNAQPTRQVILEGARVPADALLGGPDGEGTGFGI
Mvan_1361|M.vanbaalenii_PYR-1       KDTPGLSFGTDEQKMGWNAQPTKQVIFEGARVPADALLGGPDGEGTGFGI
TH_4417|M.thermoresistible__bu      KGTPGLSFGADEQKMGWNAQPTAQVILEGARVPAENMLGGPEGEGKGFSI
MSMEG_1497|M.smegmatis_MC2_155      KDTPGLSFGADEQKMGWNAQPTAQVIFEGVRVPAEALLG--NTEGTGFGI
MAB_1188c|M.abscessus_ATCC_199      KGTPGLSFGAPERKMGWHAQPTAQVVFEDVRVPVANRIG---EEGIGFTI
MLBr_00737|M.leprae_Br4923          KDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIG---EPGTGFKT
                                    *.  *:*:*. * *:* :..** :: ::  *:*    :*     * **  

Mb0774c|M.bovis_AF2122/97           AMSGLNGGRLNIAACSLGGAQAAFDKAGAYVRDRQAFGGSLLDEPTVRFT
Rv0752c|M.tuberculosis_H37Rv        AMSGLNGGRLNIAACSLGGAQAAFDKAGAYVRDRQAFGGSLLDEPTVRFT
MMAR_1078|M.marinum_M               AMNGLNGGRLNIAACSLGGAQSAFAKAGAYVRERQAFGASLLDEPTVRFT
MUL_0836|M.ulcerans_Agy99           AMNGLNGGRLNIAACSLGGAQSAFAKTGAYVRERQAFGASLLDEPTVRFT
MAV_4418|M.avium_104                AMNGLNGGRLNIAACSLGGAQAAFDKAGAYVRDRQAFGSPLLDEPTIRFA
Mflv_5011|M.gilvum_PYR-GCK          AMKGLNGGRINIAACSLGGAQAAYDKTVSYLADRQAFGGSLLDEPTIRFT
Mvan_1361|M.vanbaalenii_PYR-1       AMKGLNGGRINIAACSLGGAQTAYDKSAAYLADRQAFGGALLDEPTIRFT
TH_4417|M.thermoresistible__bu      AMNGLNGGRLNIAACSLGGAQTAYEKAASYVADRQAFGGSLIDEPTIRFT
MSMEG_1497|M.smegmatis_MC2_155      AMNGLNGGRINIAACSLGGAQAAYDKAVGYLADRQAFGAALLDEPTIRFT
MAB_1188c|M.abscessus_ATCC_199      AMRGLNGGRLNIASCSLGGARSALEKVIEYLRTRKAFGEELIKFQALQFR
MLBr_00737|M.leprae_Br4923          ALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFM
                                    *:  *:  * .*.: ::* *: *      *   *: **  :    :::* 

Mb0774c|M.bovis_AF2122/97           LADMATGLQTSRMLLWRAASALDDDDADKVELCAMAKRYVTDTCFEVADQ
Rv0752c|M.tuberculosis_H37Rv        LADMATGLQTSRMLLWRAASALDDDDADKVELCAMAKRYVTDTCFEVADQ
MMAR_1078|M.marinum_M               LADMATGLEASRMLLWRAANALDEDDADKVELCAMAKRFVTDTCFDVADK
MUL_0836|M.ulcerans_Agy99           LADMATGLEASRMLLWRAANALDEDDADKVELCAMAKRFVTDTCFDVADK
MAV_4418|M.avium_104                LADMATGLETSRMMLWRAAGALDADDPDKVELCAMAKRYVTDTCFEVADK
Mflv_5011|M.gilvum_PYR-GCK          LADMATGLETSRALLWRAATALDNDHPDRVELCAMAKRYVTDACFEVADQ
Mvan_1361|M.vanbaalenii_PYR-1       LADMATALETSRVLLWRAATALDNDHPDRVELCAMAKRYVTDACFEVADQ
TH_4417|M.thermoresistible__bu      LADMATALQTSRLMLWRAATALDENHPDKVELCAMAKLHVTEACYEVADK
MSMEG_1497|M.smegmatis_MC2_155      LADMATGLETSRNLLWRAASALDANHPDKVTLCAMAKRYVTDTCFDVADS
MAB_1188c|M.abscessus_ATCC_199      LADMATELEAARTMVWRAAAAVTEGDPRAAELCAMAKRIATDVGFTVANE
MLBr_00737|M.leprae_Br4923          LADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTD
                                    *****  ::::* ::: **     ...    :.* :*  .::    *: .

Mb0774c|M.bovis_AF2122/97           ALQLHGGYGYLREYGLEKIVRDLRVHRILEGTNEIMRLVIGRAEAARFRA
Rv0752c|M.tuberculosis_H37Rv        ALQLHGGYGYLREYGLEKIVRDLRVHRILEGTNEIMRLVIGRAEAARFRA
MMAR_1078|M.marinum_M               ALQLHGGYGYLREYGLEKIVRDLRVHRILEGTNEIMRVVVGRAEAARFRA
MUL_0836|M.ulcerans_Agy99           ALQLHGGYGYLREYGLEKIVRDLRVHRILEGTNEIMRVVVGRAEAARFRA
MAV_4418|M.avium_104                ALQLHGGYGYLREYGLEKIVRDLRVHRILEGTNEIMRVVIGRAEAARFRA
Mflv_5011|M.gilvum_PYR-GCK          ALQLHGGYGYLREYGLEKIVRDLRVHRILEGTNEIMRVVIGRSAASRARA
Mvan_1361|M.vanbaalenii_PYR-1       ALQLHGGYGYLREYGLEKIVRDLRVHRILEGSNEIMRVVIGRAAAARARA
TH_4417|M.thermoresistible__bu      ALQLHGGYGYLNEYGLEKIVRDLRVHRILEGTNEIMRVVIGRAVAGRARG
MSMEG_1497|M.smegmatis_MC2_155      ALQLHGGYGYLREYGLEKIVRDLRVHRILEGTNEIMRVVIGRSVAGAARN
MAB_1188c|M.abscessus_ATCC_199      ALQLHGGYGYLAEYGIEKIVRDLRVHQILEGTNEIMRVIVSRKLIEQGLP
MLBr_00737|M.leprae_Br4923          AVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR----
                                    *:**.** **  :: :*:::** :: :* **:*:* *:::.*        

Mb0774c|M.bovis_AF2122/97           TV---------
Rv0752c|M.tuberculosis_H37Rv        TV---------
MMAR_1078|M.marinum_M               SA---------
MUL_0836|M.ulcerans_Agy99           SA---------
MAV_4418|M.avium_104                TA---------
Mflv_5011|M.gilvum_PYR-GCK          S----------
Mvan_1361|M.vanbaalenii_PYR-1       S----------
TH_4417|M.thermoresistible__bu      AAESGRARASA
MSMEG_1497|M.smegmatis_MC2_155      QADAARPRATA
MAB_1188c|M.abscessus_ATCC_199      A----------
MLBr_00737|M.leprae_Br4923          -----------

species	id	gene	e-value	identity (len)	annotation
M. avium 104	MAV_4418	-	-	100% (386)	acyl-CoA dehydrogenase family protein member 8
M. avium 104	MAV_2668	-	2e-65	38.54% (371)	acyl-CoA dehydrogenase
M. avium 104	MAV_4243	-	1e-62	34.92% (378)	acyl-CoA dehydrogenase