For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VTMPSTLELAAPGDGVRVLRLNRPHRLNAIDEAMQTELRLVLDDLAADHAVRAVVLTGAGRGFCAGIDMR DFGPSMVGADAPALERMRFQERMAALAEAVWALPQPVIAAVNGPCVGAGLALCLAADIRICSAAATFANA AILLGLSGAEMGMSYHLPRIVGTGVAADWMLTGRTVSAAEADRRGLVSEVVEPDRLVERAVELARLIAGH APLGAQLTKRALQVNTDAASLASAMELENRNQVIAHATDEAAARRQKWSR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3942 | - | - | 100% (260) | enoyl-CoA hydratase/isomerase |
| M. avium 104 | MAV_1060 | - | 3e-47 | 45.95% (259) | enoyl-CoA hydratase/isomerase family protein |
| M. avium 104 | MAV_3307 | - | 5e-44 | 42.29% (253) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1507 | echA12 | 8e-43 | 41.60% (250) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4817 | - | 3e-52 | 46.59% (249) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv1472 | echA12 | 1e-42 | 41.60% (250) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_01241 | - | 2e-45 | 43.95% (248) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0834 | - | 2e-49 | 43.55% (248) | putative enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_2278 | echA12 | 2e-43 | 41.02% (256) | enoyl-CoA hydratase, EchA12 |
| M. smegmatis MC2 155 | MSMEG_1739 | - | 1e-50 | 41.98% (262) | enoyl-CoA hydratase/isomerase family protein |
| M. thermoresistible (build 8) | TH_2798 | - | 2e-45 | 43.65% (252) | PUTATIVE Enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_1480 | echA12 | 1e-43 | 40.77% (260) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_1625 | - | 1e-49 | 43.78% (249) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1507|M.bovis_AF2122/97 --MPHRCAAQVVAGYRSTVSLVLVEHPRPEIAQITLNRPERMNSMAFDVM
Rv1472|M.tuberculosis_H37Rv --MPHRCAAQVVAGYRSTVSLVLVEHPRPEIAQITLNRPERMNSMAFDVM
MMAR_2278|M.marinum_M ------------------MALVLLEHPRPDIALVTLNRPERMNSMAFDVM
MUL_1480|M.ulcerans_Agy99 ------------------MSLVLLEHPRPDIALVTLNRPERMNSIAFDVM
TH_2798|M.thermoresistible__bu ---------------------VLVDHPRPHIALVTLNRPERMNSMAFDVM
MLBr_01241|M.leprae_Br4923 MSQTDASCTIAELPYRSVTDLVVLDFPRPEVALITLNRPGRMNSMALDLM
MAV_3942|M.avium_104 ---------------MTMPSTLELAAPGDGVRVLRLNRPHRLNAIDEAMQ
MAB_0834|M.abscessus_ATCC_1997 --------------------MIRVEPREHGILVVTIDRPERRNALDPQTV
Mflv_4817|M.gilvum_PYR-GCK -----------------MSSVLEVARPTPEIAVLTLNRPDKLNALSYELV
Mvan_1625|M.vanbaalenii_PYR-1 -----------------MSSVVEVTRPLPEITVVTLNRPDKLNALSYELV
MSMEG_1739|M.smegmatis_MC2_155 ---------------MSLAQPLDVTRPRPDIAVLTLNRPDKLNALSYELV
: : : : ::** : *::
Mb1507|M.bovis_AF2122/97 VPLKEALAQVSYDNSVRVVVLTGAGRGFSSGADHKSAGVVPHVE------
Rv1472|M.tuberculosis_H37Rv VPLKEALAQVSYDNSVRVVVLTGAGRGFSPGADHKSAGVVPHVE------
MMAR_2278|M.marinum_M VPLKEVLEEVSYDNSVRVVVLTGAGRGFSSGADHKSAGAVPNVG------
MUL_1480|M.ulcerans_Agy99 VPLKEVLEEVSYDNSVRVVVLTGAGRGFSSGADHKSAGAVPNVG------
TH_2798|M.thermoresistible__bu VPLKAALDEITYDNDVRVVVLTGAGRGFSSGADHKSAGTVPHVD------
MLBr_01241|M.leprae_Br4923 KSLKQVLKRITYDHSVRVVVLTGAGRGFCSGADQKFTAPVPQVE------
MAV_3942|M.avium_104 TELRLVLDDLAADHAVRAVVLTGAGRGFCAGIDMR----DFGPS------
MAB_0834|M.abscessus_ATCC_1997 AELHAVIESIDGDPKVRVVVLTAVGASFCAGADLKSLPSDFTSAGVTSTA
Mflv_4817|M.gilvum_PYR-GCK EALHAELDALARDNACRAVVLTGAGRGFCSGLDLSAPNPEETGG------
Mvan_1625|M.vanbaalenii_PYR-1 ETLHDALDAVAADNTCRVVVLTGAGRGFCSGLDLSAPNPEETGG------
MSMEG_1739|M.smegmatis_MC2_155 EALHAALDDIAADNDCRVVVLTGAGRGFCSGLDLSAPNPPEAAG------
*: : : * *.****..* .*..* *
Mb1507|M.bovis_AF2122/97 ----NLTRPTYA-LRSMELLDDVILMLRRLHQPVIAAVNGPAIGGGLCLA
Rv1472|M.tuberculosis_H37Rv ----NLTRPTYA-LRSMELLDDVILMLRRLHQPVIAAVNGPAIGGGLCLA
MMAR_2278|M.marinum_M ----GLTRPTYA-LRSMELLDEVILMLRRLHQPVIAAVNGPAIGGGLCLA
MUL_1480|M.ulcerans_Agy99 ----GLTRPTYA-LRSMELLDEVILMLRRLHQPVIAAVNGPAIGGGLCLA
TH_2798|M.thermoresistible__bu ----GLTRPSYG-LRSMEVLDDVILTLRKLHQPVIAAVNGAAIGGGLCLA
MLBr_01241|M.leprae_Br4923 ----GLTQPVRA-LRAMELLEEVILALRRLHQPVIAAINGPAIGGGLCLA
MAV_3942|M.avium_104 --MVGADAPALERMRFQERMAALAEAVWALPQPVIAAVNGPCVGAGLALC
MAB_0834|M.abscessus_ATCC_1997 ALLAATDSELVRTLAAQELMASLFERIHRMRQPVIAAVNGHAIGGGFALA
Mflv_4817|M.gilvum_PYR-GCK ----GTEFPRSG-MRWQERIADLTAKIHRLRQPVIAAVQGVAYGGGLGIA
Mvan_1625|M.vanbaalenii_PYR-1 ----GTEFPRSG-MRWQERIADLTAKLHRLRQPAIAAVNGVAYGGGLGIA
MSMEG_1739|M.smegmatis_MC2_155 ----GTEFPRSG-MRWQERIANLTAKLHRLRQPVIAAVNGPAYGGGFALA
: * : : : : **.***::* . *.*: :.
Mb1507|M.bovis_AF2122/97 LAADIRVASSSAYFRAAGINNGLTASELGLSYLLPRAIGSSRAFEIMLTG
Rv1472|M.tuberculosis_H37Rv LAADIRVASSSAYFRAAGINNGLTASELGLSYLLPRAIGSSRAFEIMLTG
MMAR_2278|M.marinum_M LAADVRVAAASAYFRAAGINNGLTASELGLSYLLPRAIGSSRAFEIMLTG
MUL_1480|M.ulcerans_Agy99 LAADVRVAAASAYFRAAGINNGLTASELGLSYLLPRAIGSSRAFEIMLTG
TH_2798|M.thermoresistible__bu LAADIRIASTEAYFRAAGINNGLTASELGLSYLLPRAIGSSRAFEIMLTG
MLBr_01241|M.leprae_Br4923 LAADVRVASTRAYFRAAGINNGLSASELGLSYLLPRAVGSSRAFEIMLSG
MAV_3942|M.avium_104 LAADIRICSAAATFANAAILLGLSGAEMGMSYHLPRIVGTGVAADWMLTG
MAB_0834|M.abscessus_ATCC_1997 LACDIRFASPAASFGAVFIRHGVSNCDMGTSYHLPRLVGAARAAELMLTG
Mflv_4817|M.gilvum_PYR-GCK AACDIRVAAPTARFCTQFIKLGLGGCDIGVSYTLPRIVGAGVAFDMILTA
Mvan_1625|M.vanbaalenii_PYR-1 AACDIRVASPSARFCTQFIKLGLGGCDIGVSYTLPRILGAGPAFDMILTA
MSMEG_1739|M.smegmatis_MC2_155 AASDIRLAAESARFCTQFIKLGIGGCDIGVSYTLPRIIGAGPAFDLILTA
*.*:*..: * * * *: .::* ** *** :*:. * : :*:.
Mb1507|M.bovis_AF2122/97 RDVSAEEAERIGLVSRQVPDEQLLDACYAIAARMAGFSRPGIELTKRTLW
Rv1472|M.tuberculosis_H37Rv RDVSAEEAERIGLVSRQVPDEQLLDACYAIAARMAGFSRPGIELTKRTLW
MMAR_2278|M.marinum_M RDVTAEEAERIGLVSCRVPDGQLLDTCYAIAARMAAFSRPGIELTKRTLW
MUL_1480|M.ulcerans_Agy99 RDVTAEEAERIGLVSCRVPDGQLLDTCYAITARMAAFSRPGIELTKRTLW
TH_2798|M.thermoresistible__bu RDVDAEEAERIGLVSRRVPPAELLDTCYELADRIAGFSRPGTELTKRTLW
MLBr_01241|M.leprae_Br4923 RDVGAEEAEQIGLVSYRVSDDRLLDTCYSIAARMATFSRSGTELTKRALW
MAV_3942|M.avium_104 RTVSAAEADRRGLVSEVVEPDRLVERAVELARLIAGHAPLGAQLTKRALQ
MAB_0834|M.abscessus_ATCC_1997 RVFDAQEAYRMGLVFDVVPAEELLDAALSKAREIAVHSPLAVWMTKETMW
Mflv_4817|M.gilvum_PYR-GCK RTVAADEALRLGLVSRVS--DTPVDEALAIAETLCNYGKFGVESTKQVLW
Mvan_1625|M.vanbaalenii_PYR-1 RAVDADEALRLGLVSRVA--DSALDEALAVAETLCGFGKFGVESTKQVLW
MSMEG_1739|M.smegmatis_MC2_155 RAVDATEALRLGLVSRVC--ADVTAEAMDIAETLCGYGKFGVESTKQVLW
* . * ** : *** . : :. .. . **..:
Mb1507|M.bovis_AF2122/97 SGLDAASLEAHMQAEGLGQLFVRLLTANFEEAVAARAEQRAPVFTDDT--
Rv1472|M.tuberculosis_H37Rv SGLDAASLEAHMQAEGLGQLFVRLLTANFEEAVAARAEQRAPVFTDDT--
MMAR_2278|M.marinum_M SGLDAASLEGHMQAEGLGQLFVRLLTANFEEAVAARAEKRPAVFTDDK--
MUL_1480|M.ulcerans_Agy99 SGLDAASLEGHMQAEGLGQLFVRLLTANFEEAVAARAEKRPAVFTDDK--
TH_2798|M.thermoresistible__bu SGLDAGSLESHMHAEGLGQLYIRLLTHNFEEAVAARKEKRAPRFPDDKI-
MLBr_01241|M.leprae_Br4923 GGLDAASLDKHMQSESLAQLFIALHTSNFEEAAAPCTEKRPTVLVDARGC
MAV_3942|M.avium_104 VNTDAASLASAMELENRNQVIA---HATDEAAARRQKWSR----------
MAB_0834|M.abscessus_ATCC_1997 QTVDAPSLRHALDLENRTQVMC---TATGELRRSFDAFREGRG-------
Mflv_4817|M.gilvum_PYR-GCK ANLVASSLEAALHLENRSQILA---STSGEMRELAAKILRKG--------
Mvan_1625|M.vanbaalenii_PYR-1 ANLEASSLEAALHLENRSQILA---STSGEMREAAAKILRKP--------
MSMEG_1739|M.smegmatis_MC2_155 ANLDAGCLEAALHVENRSQILA---STEGGVRAFSEEFRRRPR-------
* .* :. *. *: .
Mb1507|M.bovis_AF2122/97 -----
Rv1472|M.tuberculosis_H37Rv -----
MMAR_2278|M.marinum_M -----
MUL_1480|M.ulcerans_Agy99 -----
TH_2798|M.thermoresistible__bu -----
MLBr_01241|M.leprae_Br4923 ATSPG
MAV_3942|M.avium_104 -----
MAB_0834|M.abscessus_ATCC_1997 -----
Mflv_4817|M.gilvum_PYR-GCK -----
Mvan_1625|M.vanbaalenii_PYR-1 -----
MSMEG_1739|M.smegmatis_MC2_155 -----