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RARIGYPEFMSNPDHRPTQVRAQAQRHAAETRAAMQERRNGQRGGLSGWVAERAARWDLSGQDEDTLQRQ KYLWNALVDYWFRMEIDGWENLPDTPPALLVGVHSGAPFVWDAWTVGLQWWRRFGPDRPLHGTAHDALMA IPLFGRYFRSMGVLPAAPDAIATALAEGRDVALWPGGEVDSLRPWTERDRANLAGRTGFVKMAIRAGVPI VPIATVGGADAMPVLIRGDRLSKALRLDRLLRLKVFPLAISLPWGIAPAALPQLPLPAKIRTRFMPPVEL DNDPARVQDDEYVERKYREVQDSIQQGMDALARRRAFPVFG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3736 | - | - | 100% (322) | acyltransferase domain-containing protein |
| M. avium 104 | MAV_3346 | - | 7e-41 | 35.27% (275) | acyltransferase domain-containing protein |
| M. avium 104 | MAV_4648 | - | 3e-17 | 30.04% (243) | acyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1463c | - | 2e-37 | 34.09% (264) | hypothetical protein Mb1463c |
| M. gilvum PYR-GCK | Mflv_1020 | - | 3e-44 | 37.68% (284) | phospholipid/glycerol acyltransferase |
| M. tuberculosis H37Rv | Rv1428c | - | 2e-37 | 34.09% (264) | hypothetical protein Rv1428c |
| M. leprae Br4923 | MLBr_02427 | - | 6e-19 | 31.28% (243) | hypothetical protein MLBr_02427 |
| M. abscessus ATCC 19977 | MAB_4002c | - | 9e-20 | 29.60% (250) | putative acyltransferase |
| M. marinum M | MMAR_1824 | - | 1e-151 | 81.67% (311) | hypothetical protein MMAR_1824 |
| M. smegmatis MC2 155 | MSMEG_0305 | - | 1e-36 | 35.37% (246) | acyltransferase domain-containing protein |
| M. thermoresistible (build 8) | TH_1905 | - | 1e-40 | 34.47% (264) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2072 | - | 1e-145 | 83.97% (287) | hypothetical protein MUL_2072 |
| M. vanbaalenii PYR-1 | Mvan_5817 | - | 2e-41 | 36.13% (274) | phospholipid/glycerol acyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1824|M.marinum_M --------------------------------------------------
MUL_2072|M.ulcerans_Agy99 --------------------------------------------------
MAV_3736|M.avium_104 --------------------------------------------------
Mb1463c|M.bovis_AF2122/97 --------------------------------------------------
Rv1428c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_0305|M.smegmatis_MC2_155 --------------------------------------------------
TH_1905|M.thermoresistible__bu --------------------------------------------------
Mflv_1020|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5817|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_02427|M.leprae_Br4923 MNSVGWGQVDTVVGETRANVIPLHIKRGRVASR-RRAGYRVDGSRQHPSL
MAB_4002c|M.abscessus_ATCC_199 -----------MAGETKAKVIQLQANSERHAARARRAEARADAGRRHPSS
MMAR_1824|M.marinum_M --------MSATD-----TSATDPRPEPLRRQAQRHAERARVAMDDKRER
MUL_2072|M.ulcerans_Agy99 -------------------------------------------MDDKRER
MAV_3736|M.avium_104 --------MRARIGYPEFMSNPDHRPTQVRAQAQRHAAETRAAMQERRNG
Mb1463c|M.bovis_AF2122/97 --------------------------------------------MSETD-
Rv1428c|M.tuberculosis_H37Rv --------------------------------------------MSETD-
MSMEG_0305|M.smegmatis_MC2_155 --------------------------------------------MAATD-
TH_1905|M.thermoresistible__bu --------------------------------------------LSPTD-
Mflv_1020|M.gilvum_PYR-GCK --------------------------------------------MAGLGD
Mvan_5817|M.vanbaalenii_PYR-1 --------------------------------------------MAGLGD
MLBr_02427|M.leprae_Br4923 LSDLRGRASAEQIAAVVREIDEHRRSTGATNLWEVTTEAPLSELAQHVAA
MAB_4002c|M.abscessus_ATCC_199 LTNGAPVHDPAETAAVIHDLNEIRAAQGNA---HVGDEESLTALAANIAA
MMAR_1824|M.marinum_M RDGGLSGWVAQRAGRWDLDGQDEATLQRQKFFWNLLVDYWFRMEIDGWEN
MUL_2072|M.ulcerans_Agy99 RDGGLSGWVAQRAGRWDLDGQDEATLQRQKFFWNLLVDYWFRMEIDGWEN
MAV_3736|M.avium_104 QRGGLSGWVAERAARWDLSGQDEDTLQRQKYLWNALVDYWFRMEIDGWEN
Mb1463c|M.bovis_AF2122/97 -----SPGNGDDAGIGDIGKFDPGLTQRLISVLRPVLKTYHRSQVHGLDS
Rv1428c|M.tuberculosis_H37Rv -----SPGNGDDAGIGDIGKFDPGLTQRLISVLRPVLKTYHRSQVHGLDS
MSMEG_0305|M.smegmatis_MC2_155 -----TDP-------GEITKWDPGLTEKVMGWLRPLIKGYHRAEVHGLDT
TH_1905|M.thermoresistible__bu -----IEP-------SEIAKWDPDLTERVMGLLRPLIKGYHRAEIRGLDT
Mflv_1020|M.gilvum_PYR-GCK VLGWVKHEVSSRVPKADLDQRDADYIREQLPGLWLLASLYFRADVRGLDR
Mvan_5817|M.vanbaalenii_PYR-1 VLEWAKREVGARVPKADLDQRDADYIREQLPGLWLLASLYFRADVRGLDR
MLBr_02427|M.leprae_Br4923 VAGFLRQRLTGDYTVDEFGFDPHFNNAIIRPFLRFFFKSWFRVEVSGIEN
MAB_4002c|M.abscessus_ATCC_199 VAEFIRRRVGGDYSVDDFGFDEHLNESLLLPLLRPLFNRWFRVDVTGVEN
:: . . :.* :: * :
MMAR_1824|M.marinum_M IPDSP-ALLIGIHSGAPFVWDAWTVGLQWWRRFGPQRPLHGTAHDALMAI
MUL_2072|M.ulcerans_Agy99 IPDSL-ALLIGIHSGAPFVWDAWTVGLQWWRRFGPQRPLHGTAHDALMAI
MAV_3736|M.avium_104 LPDTPPALLVGVHSGAPFVWDAWTVGLQWWRRFGPDRPLHGTAHDALMAI
Mb1463c|M.bovis_AF2122/97 FPPGG-ALVVANHSGGMFPMDVPVFSVDFYDKFGYDRPVYTLSHDILFMG
Rv1428c|M.tuberculosis_H37Rv FPPGG-ALVVANHSGGMFPMDVPVFSVDFYDKFGYDRPVYTLSHDILFMG
MSMEG_0305|M.smegmatis_MC2_155 FPNGG-ALVVSNHSGGLFPMDVPVFATGFYEKFGYDRPVYTLSHDMLMTG
TH_1905|M.thermoresistible__bu FPHGG-ALVVSNHSGGLFPMDVPVFATGFYERFGYDRPVYTLSHDILLTG
Mflv_1020|M.gilvum_PYR-GCK IPADGPVLLVGNHSGGNLPPDTFVFTLAFCSYFGVERPFYQLAHNLVVSM
Mvan_5817|M.vanbaalenii_PYR-1 IPPDGPVLLVGNHSGGNLPPDTFVFTLAFCSYFGVERPFYQLAHNLVVSM
MLBr_02427|M.leprae_Br4923 LPSTGGALVVANHAG-VLPFDGLMLSLAVHDEHPAQRDLRLLVADMVFDL
MAB_4002c|M.abscessus_ATCC_199 IPATGGALVVANHAG-VLPLDGLMLSVAVHDRCPGNRTLRNLAADMVFDA
:* .*::. *:* : * . :* . : :.
MMAR_1824|M.marinum_M PGIGRYFRSMGVLPAAPDAIATALAEGRDVALWPGGEVDSLRPWTERDCA
MUL_2072|M.ulcerans_Agy99 PGIGRYFRSMGVLPAAPDAIATALAEGRDVALWPGGEVDSLRPWTERDCA
MAV_3736|M.avium_104 PLFGRYFRSMGVLPAAPDAIATALAEGRDVALWPGGEVDSLRPWTERDRA
Mb1463c|M.bovis_AF2122/97 LTGD-LFRRTGYIRATRENAAKALRSGGVVVVFPGGDYDAYRPTFAENVI
Rv1428c|M.tuberculosis_H37Rv LTGD-LFRRTGYIRATRENAAKALRSGGVVVVFPGGDYDAYRPTFAENVI
MSMEG_0305|M.smegmatis_MC2_155 PTAD-FFKKTGFIRANHENADEALRSGGVVVVFPGGDYDVYRPTLAANKI
TH_1905|M.thermoresistible__bu PTAD-FFIRTGFIRANHDNADEALRSGGVVIVFPGGDYDVYRPTFAQHKI
Mflv_1020|M.gilvum_PYR-GCK PGLG-SLRKFGTVAANHDNATLALKSGAALLVYPGGDYEVFRPSWKRHEV
Mvan_5817|M.vanbaalenii_PYR-1 PGLG-SLRKFGTVAANHDNATLALKSGGALLVYPGGDYEVFRPSWKRHEV
MLBr_02427|M.leprae_Br4923 PVVGEAVRKAGHTVACTSDAHRLLAAGELTAVFPEGYKGLGKRFQDRYRL
MAB_4002c|M.abscessus_ATCC_199 PFLGQLARKAGHTLACTADAHRLLSGGELTAVFPEGYKGLGKPFKDRYKL
. * * * * ::* * :
MMAR_1824|M.marinum_M NLAGRKGFVKMAIRAGVPIVPIATVGGADAMPVLIRGDRLSRVLQ-LDRL
MUL_2072|M.ulcerans_Agy99 NLAGRKGFVKMAIRAGVPIVPIATVGGADAMPVLIRGDRLSRVLQ-LDRL
MAV_3736|M.avium_104 NLAGRTGFVKMAIRAGVPIVPIATVGGADAMPVLIRGDRLSKALR-LDRL
Mb1463c|M.bovis_AF2122/97 DFNGRKGYVSTAVEAGVPIVPAVSIGGQESQLYLSRGTWLARRLG-LKRL
Rv1428c|M.tuberculosis_H37Rv DFNGRKGYVSTAVEAGVPIVPAVSIGGQESQLYLSRGTWLARRLG-LKRL
MSMEG_0305|M.smegmatis_MC2_155 DFAGRTGYVRAALNAGVPIVPMVGVGGQETQLFLSRGTAVAKALGPIARL
TH_1905|M.thermoresistible__bu DFDGRTGYVRAALNAGVPIVPTVAVGGQESQLFLSRGESLARLLR-LDKL
Mflv_1020|M.gilvum_PYR-GCK DFGGRKGYVKLAREAGVPIVPVASVGGQEAALFLDRGQWLASLLG-VDRI
Mvan_5817|M.vanbaalenii_PYR-1 DFGGRKGYVKLSREAGVPIVPIASVGGQEAALFLDRGQWLARLLM-VDKI
MLBr_02427|M.leprae_Br4923 QRFGRGGFVKAALSTKATIVPCSIVGSEEIYPMLTDVKLLARLFG-----
MAB_4002c|M.abscessus_ATCC_199 QRFGRGGFVAAAIRTGAPIVPCSIVGSEEIYPMIADLKVIARLFG-----
: ** *:* : : ..*** :*. : : :: :
MMAR_1824|M.marinum_M LRLKVFPLAISLPWGIAPA-ALPQLPLPAKIRTRFMPAIDLDHDPDRTDD
MUL_2072|M.ulcerans_Agy99 LRLKVFPLAISLPWGIAPA-ALPQLPLPAKIRTRFMPAIDLDHDPDRTDD
MAV_3736|M.avium_104 LRLKVFPLAISLPWGIAPA-ALPQLPLPAKIRTRFMPPVELDNDPARVQD
Mb1463c|M.bovis_AF2122/97 LRSDILPISFGFPFGFSAA-IPPNLPLPAKIVMQVLDPINLTKQFG---E
Rv1428c|M.tuberculosis_H37Rv LRSDILPISFGFPFGFSAA-IPPNLPLPAKIVMQVLDPINLTKQFG---E
MSMEG_0305|M.smegmatis_MC2_155 ARTKIVPVSFGFPFGLSAV-LPLNVPLPSKIVMKTLPPIDITAEFG---E
TH_1905|M.thermoresistible__bu MRVKILPISFGFPWGLSAV-VPVNVPLPTKIVMQVLPPIDIEAEFG---P
Mflv_1020|M.gilvum_PYR-GCK ARLKSVPILLAPPWGLAVSDMIPRLPLPTKIAIEVQEPISADDIAA---D
Mvan_5817|M.vanbaalenii_PYR-1 ARLKSVPILLAPPWGLAVSDMVPRLPLPTKITIEVQDPIAPEEIAA---G
MLBr_02427|M.leprae_Br4923 --VPYFPVTPLFPLAGPAG----LVPLPSKWRIAFGEPIYTTDYAATDAD
MAB_4002c|M.abscessus_ATCC_199 --LPYFPVTPLFPAAGPVG----LVPLPSKWHIEFGTPIPTDGYDEAAAD
.*: * . . :***:* .:
MMAR_1824|M.marinum_M DAYV-DDIYHQVEGSIQHGMDALARKRALPLFG
MUL_2072|M.ulcerans_Agy99 DEYI-DDIYHQVEDSIQHGMDALARKRALPLFG
MAV_3736|M.avium_104 DEYV-ERKYREVQDSIQQGMDALARRRAFPVFG
Mb1463c|M.bovis_AF2122/97 DPDV-DAVDEHVRSVMQQALNDLAAKRRFPILG
Rv1428c|M.tuberculosis_H37Rv DPDV-DAVDEHVRSVMQQALNDLAAKRRFPILG
MSMEG_0305|M.smegmatis_MC2_155 DPDI-DEVDAHVRHVMQQALDELAEQRRFPVIG
TH_1905|M.thermoresistible__bu DPDI-DEVDAHVRRTMQRALDELAAERRLPVLG
Mflv_1020|M.gilvum_PYR-GCK DD---DAVNDRVLASLQSGVDRLAAQRRFPVLG
Mvan_5817|M.vanbaalenii_PYR-1 DD---DTVHNRVEGALQSAVDRLAAERRFPVIG
MLBr_02427|M.leprae_Br4923 DPMVTFELTDQVRETIQQTLYRLLAGRRNIFFG
MAB_4002c|M.abscessus_ATCC_199 DPMVTFEVTDQVRETIQQTLYRLLAGRRNMFFG
* .* :* : * * .:*