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AGLGDVLEWAKREVGARVPKADLDQRDADYIREQLPGLWLLASLYFRADVRGLDRIPPDGPVLLVGNHSG GNLPPDTFVFTLAFCSYFGVERPFYQLAHNLVVSMPGLGSLRKFGTVAANHDNATLALKSGGALLVYPGG DYEVFRPSWKRHEVDFGGRKGYVKLSREAGVPIVPIASVGGQEAALFLDRGQWLARLLMVDKIARLKSVP ILLAPPWGLAVSDMVPRLPLPTKITIEVQDPIAPEEIAAGDDDTVHNRVEGALQSAVDRLAAERRFPVIG *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5817 | - | - | 100% (281) | phospholipid/glycerol acyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4226 | - | 9e-55 | 46.47% (241) | phospholipid/glycerol acyltransferase |
| M. vanbaalenii PYR-1 | Mvan_0233 | - | 3e-50 | 45.68% (243) | phospholipid/glycerol acyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1463c | - | 2e-53 | 41.98% (262) | hypothetical protein Mb1463c |
| M. gilvum PYR-GCK | Mflv_1020 | - | 1e-147 | 89.68% (281) | phospholipid/glycerol acyltransferase |
| M. tuberculosis H37Rv | Rv1428c | - | 2e-53 | 41.98% (262) | hypothetical protein Rv1428c |
| M. leprae Br4923 | MLBr_02427 | - | 1e-17 | 30.36% (247) | hypothetical protein MLBr_02427 |
| M. abscessus ATCC 19977 | MAB_4002c | - | 3e-19 | 30.85% (282) | putative acyltransferase |
| M. marinum M | MMAR_2234 | - | 6e-57 | 44.70% (264) | hypothetical protein MMAR_2234 |
| M. avium 104 | MAV_3346 | - | 3e-56 | 45.38% (238) | acyltransferase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0305 | - | 3e-52 | 45.82% (251) | acyltransferase domain-containing protein |
| M. thermoresistible (build 8) | TH_1905 | - | 6e-60 | 47.33% (262) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1821 | - | 2e-57 | 44.11% (263) | hypothetical protein MUL_1821 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5817|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1020|M.gilvum_PYR-GCK --------------------------------------------------
Mb1463c|M.bovis_AF2122/97 --------------------------------------------------
Rv1428c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2234|M.marinum_M --------------------------------------------------
MUL_1821|M.ulcerans_Agy99 --------------------------------------------------
MAV_3346|M.avium_104 --------------------------------------------------
MSMEG_0305|M.smegmatis_MC2_155 --------------------------------------------------
TH_1905|M.thermoresistible__bu --------------------------------------------------
MLBr_02427|M.leprae_Br4923 MNSVGWGQVDTVVGETRANVIPLHIKRGRVASR-RRAGYRVDGSRQHPSL
MAB_4002c|M.abscessus_ATCC_199 -----------MAGETKAKVIQLQANSERHAARARRAEARADAGRRHPSS
Mvan_5817|M.vanbaalenii_PYR-1 -------------------------------------------MAGLGDV
Mflv_1020|M.gilvum_PYR-GCK -------------------------------------------MAGLGDV
Mb1463c|M.bovis_AF2122/97 -------------------------------------------MSETDSP
Rv1428c|M.tuberculosis_H37Rv -------------------------------------------MSETDSP
MMAR_2234|M.marinum_M -------------------------------------------MSDTD--
MUL_1821|M.ulcerans_Agy99 -------------------------------------------MSDTD--
MAV_3346|M.avium_104 -------------------------------------------MTDSD--
MSMEG_0305|M.smegmatis_MC2_155 -------------------------------------------MAATD--
TH_1905|M.thermoresistible__bu -------------------------------------------LSPTD--
MLBr_02427|M.leprae_Br4923 LSDLRGRASAEQIAAVVREIDEHRRSTGATNLWEVTTEAPLSELAQHVAA
MAB_4002c|M.abscessus_ATCC_199 LTNGAPVHDPAETAAVIHDLNEIRAAQGNA---HVGDEESLTALAANIAA
::
Mvan_5817|M.vanbaalenii_PYR-1 LEWAKREVGARVPKADLDQRDADYIREQLP-GLWLLASLYFRADVRGLDR
Mflv_1020|M.gilvum_PYR-GCK LGWVKHEVSSRVPKADLDQRDADYIREQLP-GLWLLASLYFRADVRGLDR
Mb1463c|M.bovis_AF2122/97 G------NGDDAGIGDIGKFDPGLTQRLIS-VLRPVLKTYHRSQVHGLDS
Rv1428c|M.tuberculosis_H37Rv G------NGDDAGIGDIGKFDPGLTQRLIS-VLRPVLKTYHRSQVHGLDS
MMAR_2234|M.marinum_M ---------NDK---DIEKFDPGLTRRMIG-VMRPVVKTYFRSEVHGLDS
MUL_1821|M.ulcerans_Agy99 ---------NDK---DIEKFDPGLTRRMIG-VMRPVVKTYFRSEVHGLDS
MAV_3346|M.avium_104 ----------NADGGDIGKFDPVLTQRLMT-VMRPVLKAYFRSEVHGLES
MSMEG_0305|M.smegmatis_MC2_155 -----------TDPGEITKWDPGLTEKVMG-WLRPLIKGYHRAEVHGLDT
TH_1905|M.thermoresistible__bu -----------IEPSEIAKWDPDLTERVMG-LLRPLIKGYHRAEIRGLDT
MLBr_02427|M.leprae_Br4923 VAGFLRQRLTGDYTVDEFGFDPHFNNAIIRPFLRFFFKSWFRVEVSGIEN
MAB_4002c|M.abscessus_ATCC_199 VAEFIRRRVGGDYSVDDFGFDEHLNESLLLPLLRPLFNRWFRVDVTGVEN
: * . : : . . :.* :: *::
Mvan_5817|M.vanbaalenii_PYR-1 IPPDGPVLLVGNHSGGNLPPDTFVFTLAFCSYFGVERPFYQLAHNLVVSM
Mflv_1020|M.gilvum_PYR-GCK IPADGPVLLVGNHSGGNLPPDTFVFTLAFCSYFGVERPFYQLAHNLVVSM
Mb1463c|M.bovis_AF2122/97 FPPGG-ALVVANHSGGMFPMDVPVFSVDFYDKFGYDRPVYTLSHDILFMG
Rv1428c|M.tuberculosis_H37Rv FPPGG-ALVVANHSGGMFPMDVPVFSVDFYDKFGYDRPVYTLSHDILFMG
MMAR_2234|M.marinum_M FPPGG-ALVVGNHSGGMFPMDVPIFSVDFYDKFGYDRPVYTLSHDILFMG
MUL_1821|M.ulcerans_Agy99 FPPGG-ALVVGNHSGGMFPMDVPIFSVDFYDKFGYDRPVYTLSHDILFMG
MAV_3346|M.avium_104 FPPGG-ALVVGNHSGGMFPMDVPIFSVHFYDKYGYDRPIYTLSHDILMTG
MSMEG_0305|M.smegmatis_MC2_155 FPNGG-ALVVSNHSGGLFPMDVPVFATGFYEKFGYDRPVYTLSHDMLMTG
TH_1905|M.thermoresistible__bu FPHGG-ALVVSNHSGGLFPMDVPVFATGFYERFGYDRPVYTLSHDILLTG
MLBr_02427|M.leprae_Br4923 LPSTGGALVVANHAG-VLPFDGLMLSLAVHDEHPAQRDLRLLVADMVFDL
MAB_4002c|M.abscessus_ATCC_199 IPATGGALVVANHAG-VLPLDGLMLSVAVHDRCPGNRTLRNLAADMVFDA
:* * .*:*.**:* :* * ::: . . :* . * :::.
Mvan_5817|M.vanbaalenii_PYR-1 PGL-GSLRKFGTVAANHDNATLALKSGGALLVYPGGDYEVFRPSWKRHEV
Mflv_1020|M.gilvum_PYR-GCK PGL-GSLRKFGTVAANHDNATLALKSGAALLVYPGGDYEVFRPSWKRHEV
Mb1463c|M.bovis_AF2122/97 LTG-DLFRRTGYIRATRENAAKALRSGGVVVVFPGGDYDAYRPTFAENVI
Rv1428c|M.tuberculosis_H37Rv LTG-DLFRRTGYIRATRENAAKALRSGGVVVVFPGGDYDAYRPTFAENVI
MMAR_2234|M.marinum_M ATG-SFFRRTGYIRASRDNAAKALRSGGVVIVFPGGDYDAYRPTLSENVI
MUL_1821|M.ulcerans_Agy99 ATG-SFFRRTGYIRASRDNAAKALRSGGVVIVFPGGDYDAYRPTLSENVI
MAV_3346|M.avium_104 PTG-DFFRRTGYIRANRENAAAALRSGGVVIVFPGGDYDAYRPTLAENVI
MSMEG_0305|M.smegmatis_MC2_155 PTA-DFFKKTGFIRANHENADEALRSGGVVVVFPGGDYDVYRPTLAANKI
TH_1905|M.thermoresistible__bu PTA-DFFIRTGFIRANHDNADEALRSGGVVIVFPGGDYDVYRPTFAQHKI
MLBr_02427|M.leprae_Br4923 PVVGEAVRKAGHTVACTSDAHRLLAAGELTAVFPEGYKGLGKRFQDRYRL
MAB_4002c|M.abscessus_ATCC_199 PFLGQLARKAGHTLACTADAHRLLSGGELTAVFPEGYKGLGKPFKDRYKL
: * * :* * .* *:* * : :
Mvan_5817|M.vanbaalenii_PYR-1 DFGGRKGYVKLSREAGVPIVPIASVGGQEAALFLDRGQWLARLLM-VDKI
Mflv_1020|M.gilvum_PYR-GCK DFGGRKGYVKLAREAGVPIVPVASVGGQEAALFLDRGQWLASLLG-VDRI
Mb1463c|M.bovis_AF2122/97 DFNGRKGYVSTAVEAGVPIVPAVSIGGQESQLYLSRGTWLARRLG-LKRL
Rv1428c|M.tuberculosis_H37Rv DFNGRKGYVSTAVEAGVPIVPAVSIGGQESQLYLSRGTWLARRLG-LKRL
MMAR_2234|M.marinum_M DFNGRKGYVSTAIEAGVPIVPAVSIGGQETQLYLSRGTWLAERLG-LKRL
MUL_1821|M.ulcerans_Agy99 DFNGRKGYVSTAIEAGVPIVPAVSIGGQETQLYLSRGTWLAERLG-LKRL
MAV_3346|M.avium_104 DFDGRKGYVRTAIEAGVPIVPAVSIGGQETQLYLTRGTWLAERLG-IKRL
MSMEG_0305|M.smegmatis_MC2_155 DFAGRTGYVRAALNAGVPIVPMVGVGGQETQLFLSRGTAVAKALGPIARL
TH_1905|M.thermoresistible__bu DFDGRTGYVRAALNAGVPIVPTVAVGGQESQLFLSRGESLARLLR-LDKL
MLBr_02427|M.leprae_Br4923 QRFGRGGFVKAALSTKATIVPCSIVGSEEIYPMLTDVKLLARLFG-----
MAB_4002c|M.abscessus_ATCC_199 QRFGRGGFVAAAIRTGAPIVPCSIVGSEEIYPMIADLKVIARLFG-----
: ** *:* : : ..*** :*.:* : :* :
Mvan_5817|M.vanbaalenii_PYR-1 ARLKSVPILLAPPWGLAVSDMVPRLPLPTKITIEVQDPIAPEEIAAGDD-
Mflv_1020|M.gilvum_PYR-GCK ARLKSVPILLAPPWGLAVSDMIPRLPLPTKIAIEVQEPISADDIAADDD-
Mb1463c|M.bovis_AF2122/97 LRSDILPISFGFPFGFSAA-IPPNLPLPAKIVMQVLDPINLTKQFGEDPD
Rv1428c|M.tuberculosis_H37Rv LRSDILPISFGFPFGFSAA-IPPNLPLPAKIVMQVLDPINLTKQFGEDPD
MMAR_2234|M.marinum_M LRSDILPLSFGFPFGFSAA-IPPNLPLPTKIVTEVLDPIDVIAQFGEDPD
MUL_1821|M.ulcerans_Agy99 LRSDILPLSFGFPFGISAA-IPPNLPLPTKIVTEVLDPIDVIVQFGEDPD
MAV_3346|M.avium_104 LRSAILPVSFGFPFGLSAV-IPPNLPLPAKIVTRVLDPIDIAKQFGEDPD
MSMEG_0305|M.smegmatis_MC2_155 ARTKIVPVSFGFPFGLSAV-LPLNVPLPSKIVMKTLPPIDITAEFGEDPD
TH_1905|M.thermoresistible__bu MRVKILPISFGFPWGLSAV-VPVNVPLPTKIVMQVLPPIDIEAEFGPDPD
MLBr_02427|M.leprae_Br4923 --VPYFPVTPLFPLAGPAG----LVPLPSKWRIAFGEPIYTTDYAATDAD
MAB_4002c|M.abscessus_ATCC_199 --LPYFPVTPLFPAAGPVG----LVPLPSKWHIEFGTPIPTDGYDEAAAD
.*: * . .. :***:* **
Mvan_5817|M.vanbaalenii_PYR-1 -----DTVHNRVEGALQSAVDRLAAERRFPVIG
Mflv_1020|M.gilvum_PYR-GCK -----DAVNDRVLASLQSGVDRLAAQRRFPVLG
Mb1463c|M.bovis_AF2122/97 V----DAVDEHVRSVMQQALNDLAAKRRFPILG
Rv1428c|M.tuberculosis_H37Rv V----DAVDEHVRSVMQQALNDLAAKRRFPILG
MMAR_2234|M.marinum_M V----DQVDQHVRSVMQEALTRLAATRRFPILG
MUL_1821|M.ulcerans_Agy99 V----DQVDQHVRSVMQEALTRLAATRRFPILG
MAV_3346|M.avium_104 V----DEVDEYVRSVMQQALNELAAERRFPILG
MSMEG_0305|M.smegmatis_MC2_155 I----DEVDAHVRHVMQQALDELAEQRRFPVIG
TH_1905|M.thermoresistible__bu I----DEVDAHVRRTMQRALDELAAERRLPVLG
MLBr_02427|M.leprae_Br4923 DPMVTFELTDQVRETIQQTLYRLLAGRRNIFFG
MAB_4002c|M.abscessus_ATCC_199 DPMVTFEVTDQVRETIQQTLYRLLAGRRNMFFG
: * :* : * ** .:*