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IASVRGEVLEVALDHAVIEAAGVGYRVNATPSTLSTLRTGTQARLITAMIVREDSMTLYGFTDAETRDLF LTLLSVSGVGPRLAMATLAVHDAGALRQALHDGDVAALTRVPGIGKRGAERMVLELRDKIGAAGAAGAPA GAARNGHAVRGPVVEALVGLGFAAKQAEEATDKVLAAEPEAGTSGALRAALSLLGKSR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_3474 | ruvA | - | 100% (199) | Holliday junction DNA helicase motor protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2624c | ruvA | 9e-86 | 83.92% (199) | Holliday junction DNA helicase RuvA |
M. gilvum PYR-GCK | Mflv_3825 | ruvA | 7e-73 | 69.04% (197) | Holliday junction DNA helicase motor protein |
M. tuberculosis H37Rv | Rv2593c | ruvA | 1e-85 | 83.92% (199) | Holliday junction DNA helicase RuvA |
M. leprae Br4923 | MLBr_00482 | ruvA | 2e-83 | 79.31% (203) | Holliday junction DNA helicase RuvA |
M. abscessus ATCC 19977 | MAB_2883c | - | 2e-73 | 71.92% (203) | Holliday junction DNA helicase RuvA |
M. marinum M | MMAR_2110 | ruvA | 3e-86 | 83.92% (199) | Holliday junction DNA helicase RuvA |
M. smegmatis MC2 155 | MSMEG_2944 | ruvA | 6e-84 | 81.73% (197) | Holliday junction DNA helicase motor protein |
M. thermoresistible (build 8) | TH_1491 | - | 3e-19 | 70.77% (65) | CONSERVED HYPOTHETICAL PROTEIN |
M. ulcerans Agy99 | MUL_1715 | ruvA | 2e-86 | 83.92% (199) | Holliday junction DNA helicase RuvA |
M. vanbaalenii PYR-1 | Mvan_2574 | ruvA | 3e-73 | 70.05% (197) | Holliday junction DNA helicase motor protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3825|M.gilvum_PYR-GCK -------------------------MIASVRGEVLDIALDHVVIEAAGVG Mvan_2574|M.vanbaalenii_PYR-1 -------------------------MIAAVRGEVLDIALDHVVIEAAGVG MSMEG_2944|M.smegmatis_MC2_155 -------------------------MIASVRGEVIDIALDHAVIEAAGVG Mb2624c|M.bovis_AF2122/97 -------------------------MIASVRGEVLEVALDHVVIEAAGVG Rv2593c|M.tuberculosis_H37Rv -------------------------MIASVRGEVLEVALDHVVIEAAGVG MAV_3474|M.avium_104 -------------------------MIASVRGEVLEVALDHAVIEAAGVG MLBr_00482|M.leprae_Br4923 -------------------------MIFSVRGEVLEVALDHAVIEAAGIG MMAR_2110|M.marinum_M -------------------------MISSLRGEVLEVALDHVVIEAAGVG MUL_1715|M.ulcerans_Agy99 -------------------------MISSLRGEVLEVALDHVVIEAAGVG MAB_2883c|M.abscessus_ATCC_199 -------------------------MIASVNGEVIDIALDHVVIEAAGVG TH_1491|M.thermoresistible__bu VANRRALVLAGGGLAGIAWETGVLLGIADESPHTADLLLTSDVLVGTSAG * .. :: * *: .:. * Mflv_3825|M.gilvum_PYR-GCK YKVMATP------------------------------------------A Mvan_2574|M.vanbaalenii_PYR-1 YKVMATP------------------------------------------A MSMEG_2944|M.smegmatis_MC2_155 YKVMATP------------------------------------------S Mb2624c|M.bovis_AF2122/97 YRVNATP------------------------------------------A Rv2593c|M.tuberculosis_H37Rv YRVNATP------------------------------------------A MAV_3474|M.avium_104 YRVNATP------------------------------------------S MLBr_00482|M.leprae_Br4923 YRVNATP------------------------------------------S MMAR_2110|M.marinum_M YRVNATP------------------------------------------S MUL_1715|M.ulcerans_Agy99 YRVNATP------------------------------------------S MAB_2883c|M.abscessus_ATCC_199 YRVNATP------------------------------------------A TH_1491|M.thermoresistible__bu SAVAAQLGSGAPLTRLFERQLDPNTAEIKPRVAIDDLTAEFLEAVRRPGS * * : Mflv_3825|M.gilvum_PYR-GCK TLATLRRGSEARLITAMIVREDS-------QTLYGFADSDAR-------- Mvan_2574|M.vanbaalenii_PYR-1 TLATLRRGAEARLITAMIVREDS-------MTLYGFADSDAR-------- MSMEG_2944|M.smegmatis_MC2_155 TLATLRRGTEARLITAMIVREDS-------MTLYGFVDGDAR-------- Mb2624c|M.bovis_AF2122/97 TLATLRQGTEARLITAMIVREDS-------MTLYGFPDGETR-------- Rv2593c|M.tuberculosis_H37Rv TLATLRQGTEARLITAMIVREDS-------MTLYGFPDGETR-------- MAV_3474|M.avium_104 TLSTLRTGTQARLITAMIVREDS-------MTLYGFTDAETR-------- MLBr_00482|M.leprae_Br4923 ALATLRQGSQARLVTAMVVREDS-------MTLYGFSDAENR-------- MMAR_2110|M.marinum_M TLATLRQGTDARLITAMIVREDS-------MTLYGFVDGETR-------- MUL_1715|M.ulcerans_Agy99 TLATLRQGTDARLITAMIVREDS-------MTLYGFVDGETR-------- MAB_2883c|M.abscessus_ATCC_199 TLSTLRRGTQIRLITAMIVREDS-------MTLYGFTDTDAR-------- TH_1491|M.thermoresistible__bu TVEKLRRIGAVALSTGTVGEAERRAVIAARLPAHDWPDRDLRLSAVDVGT :: .** * *. : . : . :.: * : * Mflv_3825|M.gilvum_PYR-GCK ---------------DLFLTLLGVSGIGPSIALGALAMYD---GPTLRQA Mvan_2574|M.vanbaalenii_PYR-1 ---------------NLFLTLLGVSGIGPSIALGALAMYD---GPTLRQA MSMEG_2944|M.smegmatis_MC2_155 ---------------DLFLTLLGVSGVGPKIALATLAVYD---PQALRQA Mb2624c|M.bovis_AF2122/97 ---------------DLFLTLLSVSGVGPRLAMAALAVHD---APALRQV Rv2593c|M.tuberculosis_H37Rv ---------------DLFLTLLSVSGVGPRLAMAALAVHD---APALRQV MAV_3474|M.avium_104 ---------------DLFLTLLSVSGVGPRLAMATLAVHD---AGALRQA MLBr_00482|M.leprae_Br4923 ---------------DLFLALLSVSGVGPRLAMATLAVHD---AAALRQA MMAR_2110|M.marinum_M ---------------DLFLTLLSVSGVGPRLAMATLSVHD---ANGLRQA MUL_1715|M.ulcerans_Agy99 ---------------DLFLTLLSVSGVGPRLAMATLSVHD---ANGLRQA MAB_2883c|M.abscessus_ATCC_199 ---------------DLFTTLLGVSGVGPKIAMATLAVYD---APTLRQA TH_1491|M.thermoresistible__bu GELVCFDRDSGVPLVDAVAASCAVPGVWPPVTIGERRYMDGGVASTVNMA : . : .*.*: * :::. * :. . Mflv_3825|M.gilvum_PYR-GCK IGDGDLTALTRIPK-------VGKKTAELLALTLRDKVGSSTSSGVAA-- Mvan_2574|M.vanbaalenii_PYR-1 IGDGDVTALTRIPK-------VGKKTAELLVLTLRDKVGTSTSAGVAS-- MSMEG_2944|M.smegmatis_MC2_155 LADGDVTALTRVPG-------IGKRGAERMVLELRDKIGPVSAGGGAA-- Mb2624c|M.bovis_AF2122/97 LADGNVAALTRVPG-------IGKRGAERMVLELRDKVGVAATGGALS-- Rv2593c|M.tuberculosis_H37Rv LADGNVAALTRVPG-------IGKRGAERMVLELRDKVGVAATGGALS-- MAV_3474|M.avium_104 LHDGDVAALTRVPG-------IGKRGAERMVLELRDKIGAAGAAGAPAGA MLBr_00482|M.leprae_Br4923 LADSDVASLTRVPG-------IGKRGAERIVLELRDKVGPVGASGLTVGT MMAR_2110|M.marinum_M LADGDVTALTRVPG-------IGKRGAERMVVELRDKVGPAGSAATAP-- MUL_1715|M.ulcerans_Agy99 LADGDVTALTRVPG-------IGKRGAERMVVELRDKVGPAGSAATAP-- MAB_2883c|M.abscessus_ATCC_199 LADGDVAALTRVPG-------IGKRGAERLVLELREKVAAAPGGTTELG- TH_1491|M.thermoresistible__bu LAADCDTVVALVPSRRDTPSPFGPGPAREIDEFGGAAVGVFADDASVAAF : . : :: :* .* *. : :. Mflv_3825|M.gilvum_PYR-GCK ---AGGHGIRGPVVEALVGLGFAVKQAEEATDKVLANDP----EATTSSA Mvan_2574|M.vanbaalenii_PYR-1 ---AGGHGIRGPVVEALVGLGFAQKQAEEATDKVLANEP----EATTSSA MSMEG_2944|M.smegmatis_MC2_155 ---VGGHAIRGPVVEALVGLGFAAKQAEEATDKVLANDP----EATTSSA Mb2624c|M.bovis_AF2122/97 ---TNGHAVRSPVVEALVGLGFAAKQAEEATDTVLAANH----DATTSSA Rv2593c|M.tuberculosis_H37Rv ---TNGHAVRSPVVEALVGLGFAAKQAEEATDTVLAANH----DATTSSA MAV_3474|M.avium_104 A--RNGHAVRGPVVEALVGLGFAAKQAEEATDKVLAAEP----EAGTSGA MLBr_00482|M.leprae_Br4923 A--ADGNAVRGSVVEALVGLGFAAKQAEEATDQVLDGELGKDGAVATSSA MMAR_2110|M.marinum_M A--VNGHTVRAPVVEALVGLGFAAKQAEEATDKVLAGDG----EATTSSA MUL_1715|M.ulcerans_Agy99 A--VNGHTVRAPVVEALVGLGFAAKQAEEATDKVLAGDG----EATTSSA MAB_2883c|M.abscessus_ATCC_199 R--GTASLVRSQVVEALIGLGFAAKQAEQATDTVLAQDNPGDTGADVSGV TH_1491|M.thermoresistible__bu GXXXGGHAVRGPVVEALVGLGFSAKQAEEATDKVLADDP----DASTSTA . :*. *****:****: ****:*** ** : . .* . Mflv_3825|M.gilvum_PYR-GCK LRAALSMLGKK- Mvan_2574|M.vanbaalenii_PYR-1 LRAALSMLGKK- MSMEG_2944|M.smegmatis_MC2_155 LRAALSMLGKK- Mb2624c|M.bovis_AF2122/97 LRSALSLLGKAR Rv2593c|M.tuberculosis_H37Rv LRSALSLLGKAR MAV_3474|M.avium_104 LRAALSLLGKSR MLBr_00482|M.leprae_Br4923 LRAALSLLGKTR MMAR_2110|M.marinum_M LRAALSLLGKAR MUL_1715|M.ulcerans_Agy99 LRAALSLLGKAR MAB_2883c|M.abscessus_ATCC_199 LRSALALLGKTR TH_1491|M.thermoresistible__bu LRSALSMLGRK- **:**::**: