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M. leprae Br4923 MLBr_02409 (-)

annotation: putative cytochrome C biogenesis protein
coordinates: 2879936 - 2880919
length: 327

NTLHVNIGLACYSDWAFTSAVVALVVALLLLAYELAYVGSRRLDNRTRVVPGSVAADSGTPGIVVDSLQR
PFGERVGQAGLAVAYLGIGLLLACILLRGLATLRVPWGNMYEFINLTCFSELVAGAIVLRRRQYRPLWVF
LLVSVLILLTISGRWLYANAAPVIPALQSYWLPIHVSVVSLGSGIFLVAGIASILFLLSTSRLVASDPEG
AKALARLVRRFPDAQTLDRIAYRTTIFAFPVFGFGVIFGAIWAEQAWGRYWGWDPKETVSFVAWVVYAAY
LHARSTAGWRDRRAAWINVVGCVAMVFNLFFVNLVTVGLHSYAGVD*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_02409--100% (327)putative cytochrome C biogenesis protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0542ccsA1e-15482.82% (326) cytochrome C-type biogenesis protein CcsA
M. gilvum PYR-GCKMflv_0049-1e-13773.07% (323) cytochrome c assembly protein
M. tuberculosis H37RvRv0529ccsA1e-15482.82% (326) cytochrome C-type biogenesis protein CcsA
M. abscessus ATCC 19977MAB_3973c-1e-12468.67% (332) cytochrome c-type biogenesis protein CcsA
M. marinum MMMAR_0875ccsB1e-15683.18% (327) cytochrome C-type biogenesis protein, CcsB
M. avium 104MAV_4616ccsB1e-15683.44% (326) cytochrome c-type biogenesis protein CcsB
M. smegmatis MC2 155MSMEG_0974ccsB1e-14676.90% (329) cytochrome c-type biogenesis protein CcsB
M. thermoresistible (build 8)TH_2248ccsB1e-13471.34% (328) POSSIBLE CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCSA
M. ulcerans Agy99MUL_0628ccsB1e-15682.57% (327) cytochrome C-type biogenesis protein, CcsB
M. vanbaalenii PYR-1Mvan_0869-1e-14175.93% (324) cytochrome c assembly protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0049|M.gilvum_PYR-GCK          --MSTTIDLDLARYSDWAFTSSVLVLVAALLLFAVELAYSRSRKVEDREL
Mvan_0869|M.vanbaalenii_PYR-1       --MSTTIDIGLARYSDWAFTSSVLVLVAALLLLAVELAYSRSRKADNREL
TH_2248|M.thermoresistible__bu      --VSTEIDIGLARYSDWAFTTSVLVLMGALLLLAIELAYARSRKVETREL
MSMEG_0974|M.smegmatis_MC2_155      MMNTEHIDIGLARYSDWAFTSSVLVLVGALLLLAVEMAYSRSRRVESREL
Mb0542|M.bovis_AF2122/97            -MNTLHVNVGLARYSDWAFTSAVVALVVALLLLAFEFAQVRGRGLAP-LA
Rv0529|M.tuberculosis_H37Rv         -MNTLHVNVGLARYSDWAFTSAVVALVVALLLLAFEFAQVRGRGLAP-LA
MLBr_02409|M.leprae_Br4923          -MNTLHVNIGLACYSDWAFTSAVVALVVALLLLAYELAYVGSRRLDNRTR
MMAR_0875|M.marinum_M               -MNTANINIDLARYSDWAFTSAVVALVVALLLLAFELAYVRGRKVDEREL
MUL_0628|M.ulcerans_Agy99           -MNTANINIDLARYSDWAFTSAVVALVVALLLLAFELAYVRGRKVDEREL
MAV_4616|M.avium_104                -MNTVHVNIELARYSDWAFTSAVVALVIALLLLAFELAYAGGRRADARAR
MAB_3973c|M.abscessus_ATCC_199      -MNSTNIDVNLAKFSDYAFTSAIVVMVGALVLLAIELAYRQSDRAAQREL
                                       :  ::: ** :**:***::::.:: **:*:* *:*   .        

Mflv_0049|M.gilvum_PYR-GCK          VGAASGR-----VSGDSSAPGVVVDAPRRSMDERLGAAGMSLTYVGIALL
Mvan_0869|M.vanbaalenii_PYR-1       VTAGGGAG----VAHDSAAPGVVVDAPRRPFDERMGTAGVALTYVGILLL
TH_2248|M.thermoresistible__bu      AAAGVAASGAVTTSPGAAAPGVVVEAPKRPVDERIGGAGLALAYVGIAAL
MSMEG_0974|M.smegmatis_MC2_155      VGAGGPS----VVGADSATPGVVVESPKRPFDERVGKTGLALTYVGIGLL
Mb0542|M.bovis_AF2122/97            VPAGSVAT-------DSATPGIVADQRHRPFDERVGRGGLAVAYLGIGLL
Rv0529|M.tuberculosis_H37Rv         VPAGSVAT-------DSATPGIVADQRHRPFDERVGRGGLAVAYLGIGLL
MLBr_02409|M.leprae_Br4923          VVPGSVAA-------DSGTPGIVVDSLQRPFGERVGQAGLAVAYLGIGLL
MMAR_0875|M.marinum_M               VLAGSVAS-------DATTPGIVLDGPQRPLDERVGRAGLAVVYLGIGLL
MUL_0628|M.ulcerans_Agy99           VLAGSVAS-------DATTPGIVLDGPRRPLDERVGRAGLAVVYLGIGLL
MAV_4616|M.avium_104                VLAGAVSA-------DSATPGVVDEVPRRPVDERAGRAGLAVVYLGTGLL
MAB_3973c|M.abscessus_ATCC_199      VSSGGDVV-----AAGENRPGLVVPQGRRPLAERVGGAGQALAYLGIGLL
                                    . ..           .   **:*    :*.. ** *  * ::.*:*   *

Mflv_0049|M.gilvum_PYR-GCK          LACIVLRGLSTSRVPWGNMYEFINLTCFCGLVAAAWVLR----KPQYRSL
Mvan_0869|M.vanbaalenii_PYR-1       AACIVLRGLSTSRVPWGNMYEFINLTSFCGLVAAAWVLR----RPQYRSL
TH_2248|M.thermoresistible__bu      LGSIVLRGLATGRAPWGNMYEFVNVTCLCGLVAAAVMLR----RARYRPL
MSMEG_0974|M.smegmatis_MC2_155      LVCIVLRGVSTSRVPWGNMYEFINLTCFCGLVAAAVVLR----RPQYRTL
Mb0542|M.bovis_AF2122/97            LACVVLRGLATQRVPWGNMYEFINLTCLSGLIAGAVVLR----RARYRPL
Rv0529|M.tuberculosis_H37Rv         LACVVLRGLATQRVPWGNMYEFINLTCLSGLIAGAVVLR----RARYRPL
MLBr_02409|M.leprae_Br4923          LACILLRGLATLRVPWGNMYEFINLTCFSELVAGAIVLR----RRQYRPL
MMAR_0875|M.marinum_M               LACIVLRGLATMRVPWGNMYEFINLTCMSGLIAGAVVLR----RPQYRSL
MUL_0628|M.ulcerans_Agy99           LACIVLRGLATMRVPWGNMYEFINLTCMSGLIAGAVVLR----RPQYRSL
MAV_4616|M.avium_104                LACLVLRGLATLRVPWGNMYEFINLTCLCGLVAGAIVLR----RPQYRPL
MAB_3973c|M.abscessus_ATCC_199      LLCIVLRGVATTRVPWGNMYEFINLTCACGLVTAAIVLRPRGNAEGRRAL
                                      .::***::* *.********:*:*. . *::.* :**        *.*

Mflv_0049|M.gilvum_PYR-GCK          WVFVLVPVLILLTVSGKWLYSHAAPVMPALQSYWLPIHVSVVSLGSGVFL
Mvan_0869|M.vanbaalenii_PYR-1       WVFVLVPVLILLTVSGKWLYSHAAPVMPALQSYWLPIHVSVVSLGSGVFL
TH_2248|M.thermoresistible__bu      WVFVLVPVLILLTVSGRWLYTDAAPVMPALQSYWLPIHVSVVSLGSGVFL
MSMEG_0974|M.smegmatis_MC2_155      WVFVLVPVLILLTVSGRWLYTNAAPVMPALQSYWLPIHVSVVSLGSGVFL
Mb0542|M.bovis_AF2122/97            WVFLLVPVLILLTVSGRWLYANAAPVMPALQSYWLPIHVSVVSLGSGVFL
Rv0529|M.tuberculosis_H37Rv         WVFLLVPVLILLTVSGRWLYANAAPVMPALQSYWLPIHVSVVSLGSGVFL
MLBr_02409|M.leprae_Br4923          WVFLLVSVLILLTISGRWLYANAAPVIPALQSYWLPIHVSVVSLGSGIFL
MMAR_0875|M.marinum_M               WVFLLLPVLILLTVSGRWLYTNAAPVMPALQSYWLPIHVSVVSLGSGVFL
MUL_0628|M.ulcerans_Agy99           WVFLLLPVLILLTVSGRWLYTNAAPVMPALQSYWLPIHVSVISLGSGVFL
MAV_4616|M.avium_104                WVFLLLPVLILLTVSGRWLYTNAAPVMPALQSYWLPIHVSVVSLGSGVFL
MAB_3973c|M.abscessus_ATCC_199      WVFVLIPVLILLAVSGRYLYTYAAPVMPALQSYWLPIHVSVVSLGSGVFL
                                    ***:*:.*****::**::**: ****:**************:*****:**

Mflv_0049|M.gilvum_PYR-GCK          VAGVASILFLVKMSRLAD----RDD-AIGRIVAKLPDGQTLDRIAYRTTI
Mvan_0869|M.vanbaalenii_PYR-1       VAGVASILFLLKMSRLGDP--GRTD-AIGRIVAKLPDAQTLDRIAYRTTI
TH_2248|M.thermoresistible__bu      VAGVASILFLVKMSRFGQV--AGDG-LWARIVDRLPDAQTLDRIAYRATI
MSMEG_0974|M.smegmatis_MC2_155      VAGVASILFLLKMSPLGQPQEGRDS-VWARIIDRVPDAQTLDRIAYRTTI
Mb0542|M.bovis_AF2122/97            VAGVASILFLVRTSRLG--EPTGEG-ALAGMVRRLPDAQTLDGIAYRTTI
Rv0529|M.tuberculosis_H37Rv         VAGVASILFLVRTSRLG--EPTGEG-ALAGMVRRLPDAQTLDGIAYRTTI
MLBr_02409|M.leprae_Br4923          VAGIASILFLLSTSRLVASDPEGAK-ALARLVRRFPDAQTLDRIAYRTTI
MMAR_0875|M.marinum_M               VAGISSILFLLRTSRLGAPDSQPAESTLGRLVQRLPDAQTLDRIAYRTTI
MUL_0628|M.ulcerans_Agy99           VAGISSILFLLRTSRLGAPDSQPAESTLGRLVQRLPDAQTLDRIAYRTTI
MAV_4616|M.avium_104                VAGIASILFLLRTSPLG--DPGNDS-APARLVRRFPDAQTLDRIAYRTTI
MAB_3973c|M.abscessus_ATCC_199      VAGVASILFLAKMYFPD-----------NSFVQRLPDAQALDRLAYRTTI
                                    ***::*****                    :: :.**.*:** :***:**

Mflv_0049|M.gilvum_PYR-GCK          FAFPVFGFGVIFGAIWAEEAWGRYWGWDPKETVSFIAWVVYAAYLHARST
Mvan_0869|M.vanbaalenii_PYR-1       FAFPVFGFGVIFGAIWAEEAWGRYWGWDPKETVSFIAWVIYAAYLHARST
TH_2248|M.thermoresistible__bu      FAFPVFGFGVIFGAIWAEEAWGRYWGWDPKETVSFIAWVVYAAYLHARST
MSMEG_0974|M.smegmatis_MC2_155      FAFPVFGFGVIFGAIWAEEAWGRYWGWDPKETVSFIAWVVYAAYLHARST
Mb0542|M.bovis_AF2122/97            FAFPVFGFGVIFGAIWAEEAWGRYWGWDPKETVSFVAWVVYAAYLHARST
Rv0529|M.tuberculosis_H37Rv         FAFPVFGFGVIFGAIWAEEAWGRYWGWDPKETVSFVAWVVYAAYLHARST
MLBr_02409|M.leprae_Br4923          FAFPVFGFGVIFGAIWAEQAWGRYWGWDPKETVSFVAWVVYAAYLHARST
MMAR_0875|M.marinum_M               FAFPVFGFGVIFGAIWAEQAWGRYWGWDPKETVSFVAWVVYAAYLHARST
MUL_0628|M.ulcerans_Agy99           FAFPVFGFGVIFGAIWAEQAWGRYWGWDPKETVSFVAWVVYAAYLHARST
MAV_4616|M.avium_104                FAFPVFGFGVIFGAIWAEEAWGRYWGWDPKETVSFVAWVIYAAYLHARST
MAB_3973c|M.abscessus_ATCC_199      FGFPIFGFGVIFGAIWAEEAWGRFWAWDPKETVSFVAWVIYAAYLHARST
                                    *.**:*************:****:*.*********:***:**********

Mflv_0049|M.gilvum_PYR-GCK          AGWRDRKAAWINIAGFVAMVFNLFFINLVTVGLHSYAGVG
Mvan_0869|M.vanbaalenii_PYR-1       AGWRDKKAAWINVAGFVAMVFNLFFINLVTVGLHSYAGVG
TH_2248|M.thermoresistible__bu      AGWRDRKAAWINVIGFVAMVFNLFFINLVTVGLHSYAGVG
MSMEG_0974|M.smegmatis_MC2_155      AGWRDRKAAWINVVGFVAMVFNLFFINLVTVGLHSYAGVG
Mb0542|M.bovis_AF2122/97            AGWRDRKAAWINVAGFVAMVFNLFFVNLVTVGLHSYAGVG
Rv0529|M.tuberculosis_H37Rv         AGWRDRKAAWINVAGFVAMVFNLFFVNLVTVGLHSYAGVG
MLBr_02409|M.leprae_Br4923          AGWRDRRAAWINVVGCVAMVFNLFFVNLVTVGLHSYAGVD
MMAR_0875|M.marinum_M               AGWRDRKAAWINVAGFVAMVFNLFFVNLVTVGLHSYAGVG
MUL_0628|M.ulcerans_Agy99           AGWRDRKAAWINVAGFVAMVFNLFFVNLVTVGLHSYAGVV
MAV_4616|M.avium_104                AGWRDRKAAWINVAGFVAMVFNLFFVNLVTVGLHSYAGVG
MAB_3973c|M.abscessus_ATCC_199      AGWRDKKAAWINVAGFVAMVFNLFFVNLVTVGLHSYAGVS
                                    *****::*****: * *********:*************