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MWGSVLGLGMLAALNPVRLGLALLMISRPRPGPSLLAYWIGGLTVCVPELLIPVLLLNFTPMFGHPSHAS PSTGSALGKIQIGLGVVGLSIAAVLTVRFAARQRAAAPPPDDRTSELSAAPGATIAMPRLLTRAQDVSPD DRSVLRRLLGRMHSAWESGASWVAWVIGVISVPVDGVLFIVAIIAASGASVTAQVSASVAFVVLMYAVVE VILVGYLATPGKTQSLLLVLHDWVRTYHRQILVALFTVVGVSQLAQGLHLV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3059 | - | - | 100% (261) | hypothetical protein MAV_3059 |
| M. avium 104 | MAV_1758 | - | 3e-19 | 27.73% (256) | hypothetical protein MAV_1758 |
| M. avium 104 | MAV_4839 | - | 3e-09 | 24.06% (266) | hypothetical protein MAV_4839 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1544 | - | 6e-28 | 32.96% (267) | hypothetical protein Mb1544 |
| M. gilvum PYR-GCK | Mflv_0400 | - | 8e-22 | 31.32% (265) | hypothetical protein Mflv_0400 |
| M. tuberculosis H37Rv | Rv1517 | - | 4e-28 | 32.96% (267) | hypothetical protein Rv1517 |
| M. leprae Br4923 | MLBr_01233 | - | 1e-24 | 29.34% (259) | hypothetical protein MLBr_01233 |
| M. abscessus ATCC 19977 | MAB_4697 | - | 2e-51 | 39.62% (260) | hypothetical protein MAB_4697 |
| M. marinum M | MMAR_2352 | - | 7e-36 | 32.31% (260) | hypothetical protein MMAR_2352 |
| M. smegmatis MC2 155 | MSMEG_0403 | - | 1e-44 | 36.65% (281) | integral membrane protein |
| M. thermoresistible (build 8) | TH_4435 | - | 1e-33 | 33.71% (264) | PUTATIVE putative conserved hypothetical transmembrane protein |
| M. ulcerans Agy99 | MUL_1527 | - | 3e-36 | 32.31% (260) | hypothetical protein MUL_1527 |
| M. vanbaalenii PYR-1 | Mvan_0277 | - | 4e-22 | 31.80% (261) | hypothetical protein Mvan_0277 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0400|M.gilvum_PYR-GCK ----MWITLLAMAVAVSLEPFRIGMTVLMINRPRPGLQLLAFLTGGFAMG
Mvan_0277|M.vanbaalenii_PYR-1 ----MWFPLLVMAAAVSLEPFRIGMTVVMVNRPRPVLQLLSFLAGGFVMG
MLBr_01233|M.leprae_Br4923 ----MWITILLMAIAISLEPFRIGMTVLMLNRPRPTLQLLVFLCSGFTMG
TH_4435|M.thermoresistible__bu VFGTMWGAVVLFALMAMGEPLRIGAAVLLISRPRPMFNLFLFWLGGIVAT
Mb1544|M.bovis_AF2122/97 ----MWTMVLLLGLGMAIDPARLGLAVVMLSRRRPMLNLFAFWVGGMVAG
Rv1517|M.tuberculosis_H37Rv ----MWTMVLLLGLGMAIDPARLGLAVVMLSRRRPMLNLFAFWVGGMVAG
MMAR_2352|M.marinum_M ----MWTTVLILAVMTATEPVRLGVAIFLVSKPRPMVNLLAFWFGGMATG
MUL_1527|M.ulcerans_Agy99 ----MWTTVLILAVMTATEPVRLGVAIFLVSKPRPMVNLLAFWFGGMATG
MAV_3059|M.avium_104 ----MWGSVLGLGMLAALNPVRLGLALLMISRPRPGPSLLAYWIGGLTVC
MAB_4697|M.abscessus_ATCC_1997 ----MWGSVLALVVLVALNPIRLGITLLVISRPKPVPNLLVYWAGCLIGC
MSMEG_0403|M.smegmatis_MC2_155 ----MWSDILGLALFVSLNPLLLGFILLVLSRPRPVPNLVVFWVGCLIVN
** :: : :* :* :.::.: :* .*. : . :
Mflv_0400|M.gilvum_PYR-GCK TAVGVAVLFLLR---------PVLDS-------AQFTLPRVQIVVGLVVL
Mvan_0277|M.vanbaalenii_PYR-1 TAVGLIVLFVLR---------PALGS-------AHFTLPRVQLGVGAVVL
MLBr_01233|M.leprae_Br4923 MTVGFVVLFVFRR--------RLMAS-------MQLTLPKVQILIGVLAL
TH_4435|M.thermoresistible__bu VLAGVVVLFLLRDVIGVVTAAAAASG-------SAIDIMSIQIAVGALAL
Mb1544|M.bovis_AF2122/97 VGIALAVLVFMRDVALAAIQGVVSAANEFREAVGILAGGRLHIVIGVIML
Rv1517|M.tuberculosis_H37Rv VGIALAVLVFMRDVALAAIQGVVSAANEFREAVGILAGGRLHIVIGVIML
MMAR_2352|M.marinum_M IGVALAVLLLLGDLANAIVDNVSSLA-----ATSVVG--HLQVGLGVVAL
MUL_1527|M.ulcerans_Agy99 IGVALAVLLLLGDLANAIVDNVSSLA-----ATSVVG--HLQVGLGVVAL
MAV_3059|M.avium_104 VPELLIPVLLLNFTPMFGHPSHASPSTG-----SA--LGKIQIGLGVVGL
MAB_4697|M.abscessus_ATCC_1997 IPAVVLPLTLLHVTPVFRSFAEG-VAIS-----PT--IRHIQVGMGLLAL
MSMEG_0403|M.smegmatis_MC2_155 VPGFLIPLFVLRAVPSFAEFAEDLTTAD-----PSSGIEPFQLGTGIFAL
. : .: .:: * . *
Mflv_0400|M.gilvum_PYR-GCK CTAAAVGSGLVGR------------------PRDPGRAPG---VLAMR--
Mvan_0277|M.vanbaalenii_PYR-1 VNAVLLATGVLGG------------------NRD-GTAAGRWAPLVTR--
MLBr_01233|M.leprae_Br4923 LVAAVLTVQVCISSEPPAES-----------PVDSASGPPKPSKWAPRP-
TH_4435|M.thermoresistible__bu ALAPVILLRSAARRKAAAPVGGPDWPTGRGPSVDSSDAPSAFSRLSAR--
Mb1544|M.bovis_AF2122/97 LLAARMVARARAQVGVPVGPVGVADG-GMSALALAQRPPGLVARLEVR--
Rv1517|M.tuberculosis_H37Rv LLAARMVARARAQVGVPVGPVGVADG-GMSALALAQRPPGLVARLEVR--
MMAR_2352|M.marinum_M LVAA-LVATG-FSVRSPA-LVASGAG-DSSTLMVAETPT-RFSRLMAS--
MUL_1527|M.ulcerans_Agy99 LVAA-LVATG-FSVRSPA-LVASGAG-DSSTLMVAETPT-RFSRLMAS--
MAV_3059|M.avium_104 SIAAVLTVRFAARQRAAAPPPD-----DRTSELSAAPGATIAMPRLLTRA
MAB_4697|M.abscessus_ATCC_1997 SVAVLIATRPLLRQRQYHMAIS-----GNVPPTDADSPAPNPLSRLLGHA
MSMEG_0403|M.smegmatis_MC2_155 AVSAVIALRMWVKRRANQPVLVGSGAGDRGPTDDASTLVLDSGAREAREP
: :
Mflv_0400|M.gilvum_PYR-GCK --------------------ARRLLDGRSLWTAAAVGLGTAL-PSVDYLA
Mvan_0277|M.vanbaalenii_PYR-1 --------------------ARRLLEGRSLWTAGVAGLGIAL-PSIDYLA
MLBr_01233|M.leprae_Br4923 --------------------LARLLNGDSLWVAGVAGLGIAL-PSVDYLA
TH_4435|M.thermoresistible__bu --------------------VQGVLQGGSPWVAFFIGAWLGPGPPVELVA
Mb1544|M.bovis_AF2122/97 --------------------TQQMLQGDVVWPAFVVGVASSAPP-FESVV
Rv1517|M.tuberculosis_H37Rv --------------------TQQMLQGDVVWPAFVVGVASSAPP-FESVV
MMAR_2352|M.marinum_M --------------------AQGALEGGFPWAAFVVGLSSAGPPPVEYLV
MUL_1527|M.ulcerans_Agy99 --------------------AQGALEGGFPWAAFVVGLSSAGPPPVEYLV
MAV_3059|M.avium_104 QDVS---PDDRSVLRRLLGRMHSAWESGASWVAWVIGVIS--VPVDGVLF
MAB_4697|M.abscessus_ATCC_1997 DDDT---SQDRSPFRRMLNRATFAWETGSLWVAFAIGLLLGGIEPDAGLF
MSMEG_0403|M.smegmatis_MC2_155 GAIARMILRMRSALQRLVSRLHQEWENGALWVALVFGLAY-IPPPPLVLL
: * * * :
Mflv_0400|M.gilvum_PYR-GCK ALALIAASGAAAATQFGALMAFNAVAFALIEIPLLCYLVSPDRTRAVLAS
Mvan_0277|M.vanbaalenii_PYR-1 ALALIVASGAAAAVQFSALIVFNVVAFALVEIPLLCYLVAPDRTRAALSS
MLBr_01233|M.leprae_Br4923 ALAVILTSGAAATTQVGALLMFNVVAFALIEIPLAAYLLAPDTTRAWTAA
TH_4435|M.thermoresistible__bu ALTAIVASGATAGTQVGAVVVFALVMFAFAEIPLISHLVAPTRTEAVMMR
Mb1544|M.bovis_AF2122/97 ALTVIMASGAEIGTQFGAFVVFTLLVLAVIEIPLVAYLAIPQQTQQVMLR
Rv1517|M.tuberculosis_H37Rv ALTVIMASGAEIGTQLGAFVVFTLLVLAVIEIPLVAYLAIPQQTQQVMLR
MMAR_2352|M.marinum_M ALTAIGASGAAMGTQLSATFVYLLVMLAIIEIPLISYLVHPGRTEATMLW
MUL_1527|M.ulcerans_Agy99 ALTAIGVSGAAMGTQLSATFVYLLVMLAIIEIPLIGYLVHPGRTEATMLW
MAV_3059|M.avium_104 IVAIIAASGASVTAQVSASVAFVVLMYAVVEVILVGYLATPGKTQSLLLV
MAB_4697|M.abscessus_ATCC_1997 LIAILVTSGANTATQIIVAAVFALGVLAIVELTLISYLVAPTKTHAVVQR
MSMEG_0403|M.smegmatis_MC2_155 VDTIIGGSGAPIGTQIIAVFVFIMAMLAVFEITLLSYVIAPRRTQAVLEP
: : *** .*. . : *. *: * :: * *.
Mflv_0400|M.gilvum_PYR-GCK LNSWIRARGRVGVCALMAIVGGVLLVVGLAGL
Mvan_0277|M.vanbaalenii_PYR-1 LYEWVRAQGRRGVSLLLAVVGCVLVAVGFAGL
MLBr_01233|M.leprae_Br4923 LNNWIRSRRRLEVATLLAGVSCLLLAVGIAGL
TH_4435|M.thermoresistible__bu LHTWVRVHRGRVFAVGLAVLGGYLLGTGLTG-
Mb1544|M.bovis_AF2122/97 FQDWVRSNRRQISLTILIGVGFLFLYQGVTSL
Rv1517|M.tuberculosis_H37Rv FQDWVRSNRRQISLTILIGVGFLFLYQGVTSL
MMAR_2352|M.marinum_M LRNWLRAHRRQIIAVAVGLAGIALVTNGMGTI
MUL_1527|M.ulcerans_Agy99 LRNWLRAHRRQIIAVAVGLAGIALVTNGMGTI
MAV_3059|M.avium_104 LHDWVRTYHRQILVALFTVVGVSQLAQGLHLV
MAB_4697|M.abscessus_ATCC_1997 VHDWALTHRRKILIAMCMVAGISLLIHGLGGI
MSMEG_0403|M.smegmatis_MC2_155 LHEWSHRHRQMILLVLFGAVGIWELIVGLGVI
. * . : *.