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MNDRRSFASTPVARLACVALCAAALAGCQQPHKPAPTSSSTTPTTTASPAAPAAPPPTVRIAPLPVRPVT KSQPTTPAVKCPAIDPTVPVPPTDGLTTCDIARATVYTLGPEAMQLGLINVDPPKSLTADYYEVTLVLDP ASASAWAAFTGEHPKDHIAFIRDNLVVEAPIIEEQVTSGRIALTTQTAQGAAQLAQLVGRPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2986 | - | - | 100% (202) | protein export protein SecD, putative |
| M. avium 104 | MAV_3468 | secD | 5e-10 | 26.32% (209) | preprotein translocase subunit SecD |
| M. avium 104 | MAV_4824 | - | 2e-05 | 37.04% (81) | hypothetical protein MAV_4824 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2618c | secD | 1e-09 | 24.52% (261) | preprotein translocase subunit SecD |
| M. gilvum PYR-GCK | Mflv_3816 | secD | 2e-07 | 24.31% (181) | preprotein translocase subunit SecD |
| M. tuberculosis H37Rv | Rv2587c | secD | 1e-09 | 24.52% (261) | preprotein translocase subunit SecD |
| M. leprae Br4923 | MLBr_00487 | secD | 2e-07 | 26.56% (192) | preprotein translocase subunit SecD |
| M. abscessus ATCC 19977 | MAB_2880c | secD | 4e-06 | 37.33% (75) | preprotein translocase subunit SecD |
| M. marinum M | MMAR_2120 | secD | 1e-07 | 27.32% (194) | protein-export membrane protein SecD |
| M. smegmatis MC2 155 | MSMEG_2961 | secD | 8e-09 | 29.59% (196) | preprotein translocase subunit SecD |
| M. thermoresistible (build 8) | TH_1363 | secD | 2e-05 | 30.00% (120) | PROBABLE PROTEIN-EXPORT MEMBRANE PROTEIN SECD |
| M. ulcerans Agy99 | MUL_1725 | secD | 8e-08 | 27.32% (194) | preprotein translocase subunit SecD |
| M. vanbaalenii PYR-1 | Mvan_2583 | secD | 2e-09 | 28.49% (186) | preprotein translocase subunit SecD |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3816|M.gilvum_PYR-GCK --------------------------MASSST-VHPARYLALFLVLLIGA
Mvan_2583|M.vanbaalenii_PYR-1 --------------------------MASSST-VHPARYLALFLAMLIGA
TH_1363|M.thermoresistible__bu --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 --------------------------MASSSAPVHPARYLTLFLVLLVGV
MAB_2880c|M.abscessus_ATCC_199 --------------------------MASSSAPVHPMRYLAAFLVLLIGA
Mb2618c|M.bovis_AF2122/97 --------------------------MASSSAPVHPARYLSVFLVMLIGI
Rv2587c|M.tuberculosis_H37Rv --------------------------MASSSAPVHPARYLSVFLVMLIGI
MMAR_2120|M.marinum_M --------------------------MASSSAPVHPARYLSVFLVLLIGV
MUL_1725|M.ulcerans_Agy99 --------------------------MASSSAPVHPARYLSVFLVLLIGV
MLBr_00487|M.leprae_Br4923 MSCVKGLVMRHVGSVGKNRFRGDTRNVASSSAPVHFGRYLSMFLVLFIGV
MAV_2986|M.avium_104 --------------------------------------------------
Mflv_3816|M.gilvum_PYR-GCK FLLVFFTGDKKPDPKLGIDLQGGTRVTLTARTPDGSEPSRDALLQAQQII
Mvan_2583|M.vanbaalenii_PYR-1 YLLVFLTGDKKPDPKLGIDLQGGTRVTLTARTPDGSPPSRESLDQAKQII
TH_1363|M.thermoresistible__bu --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 YLLVFLTGDKKPEPKLGIDLQGGTRVTLTARTPDGSAPTRDALNQAQQII
MAB_2880c|M.abscessus_ATCC_199 YLLVFLTGDKQPKPKLGIDLQGGTRVTLTARTPDGSKPTKEALTQAQQII
Mb2618c|M.bovis_AF2122/97 YLLVFFTGDKHTAPKLGIDLQGGTRVTLTARTPDGSAPSREALAQAQQII
Rv2587c|M.tuberculosis_H37Rv YLLVFFTGDKHTAPKLGIDLQGGTRVTLTARTPDGSAPSREALAQAQQII
MMAR_2120|M.marinum_M YLLVFLTGDKKAAPKLGIDLQGGTRVTLTARTPDGSAPSREALAQAQQII
MUL_1725|M.ulcerans_Agy99 YLLVFLTGDKKAAPKLGIDLQGGTRVTLTARTPDGSAPSREALAQAQQII
MLBr_00487|M.leprae_Br4923 YLLAFLTGDKRVVPRLGIDLQGGTRVTLTARTPDGSRPSREALSQAQQII
MAV_2986|M.avium_104 --------------------------------------------------
Mflv_3816|M.gilvum_PYR-GCK SARVDGLGVSGSEVIIDGNNLVITVPGDDTSEARSLGQTARLYIRPVVHA
Mvan_2583|M.vanbaalenii_PYR-1 GARVDGLGVSGSEVIIDGQNLVITVPGDDTSEARSLGQTARLYIRPVVHV
TH_1363|M.thermoresistible__bu --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 SARVDGLGVSGSEVVIDGDNLVITVPGNDGNEARNLGQTARLYIRPVIHA
MAB_2880c|M.abscessus_ATCC_199 NARVNGLGVSGSEVIIDGDNLVITVPGNDGSEARNLGQTAKLYIRPVVQA
Mb2618c|M.bovis_AF2122/97 SARVNGLGVSGSEVVVDGDNLVITVPGNDGSEARNLGQTARLYIRPVLNS
Rv2587c|M.tuberculosis_H37Rv SARVNGLGVSGSEVVVDGDNLVITVPGNDGSEARNLGQTARLYIRPVLNS
MMAR_2120|M.marinum_M SARVNGLGVSGSEVVVDGDNLVITVPGNDGNEARNLGQTARLYIRPVMNS
MUL_1725|M.ulcerans_Agy99 SARVNGLGVSGSEVVVDGDNLVITVPGNDGNEARNLGQTARLYIRPVMNS
MLBr_00487|M.leprae_Br4923 SSRVNGLGVSGSEVVVDGDNLVITVPGNDGNEARNLGQTARLYIRPVLNS
MAV_2986|M.avium_104 ---MNDRRSFASTPVARLACVALCAAALAGCQQPHKPAPTSSSTTPTTTA
Mflv_3816|M.gilvum_PYR-GCK IPAGEGAAPGGAPEGMPPGAIPGMPGGVPGMPPGAIPGMP-PGAIPGMPG
Mvan_2583|M.vanbaalenii_PYR-1 IPS-AAAAP---PEQAGPQGVP--PGGVPGVPPGAVPGLP-PGAVP----
TH_1363|M.thermoresistible__bu --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 MAAQPPTEDGQPPAGAP--GAPGAPGGAPGAPG--LPGLPGLSGLPGMPG
MAB_2880c|M.abscessus_ATCC_199 VPAQPKENP--------------EPG--AGAPQ-----------------
Mb2618c|M.bovis_AF2122/97 MPAQPAAEEPQ-----------PAPSAEPQPPG-----------------
Rv2587c|M.tuberculosis_H37Rv MPAQPAAEEPQ-----------PAPSAEPQPPG-----------------
MMAR_2120|M.marinum_M MPAQPAAQEPQQEPQQP-GGTAPAPGGPAPNAG-----------------
MUL_1725|M.ulcerans_Agy99 MPAQPAAQEPQQEPQQP-GGTAPAPGGPAPNAG-----------------
MLBr_00487|M.leprae_Br4923 LPVQ-RGQDPK-------------PGSPAG--------------------
MAV_2986|M.avium_104 SPAAPAAPP-----------------------------------------
Mflv_3816|M.gilvum_PYR-GCK DA-MPGMPEGAMP-LPPG--ALQGGPGGPGEPVAPAPQPRPFPQQP----
Mvan_2583|M.vanbaalenii_PYR-1 ----PGAPPGAVPGLPPA--AVP--PEAPPASDTPAPQPRPFPQQP----
TH_1363|M.thermoresistible__bu --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 APGAPGAPQEAPPGMPVPGEAPGGEAPAPPAGEQPAPQPRPYPLEP----
MAB_2880c|M.abscessus_ATCC_199 ----QGQPAPAKEATPPAPGAGKSTPAAPP---SPKPQPRPYPAQT----
Mb2618c|M.bovis_AF2122/97 --------QP---AAPPPAQSGAPASPQ------PGAQPRPYPQDP----
Rv2587c|M.tuberculosis_H37Rv --------QP---AAPPPAQSGAPASPQ------PGAQPRPYPQDP----
MMAR_2120|M.marinum_M --------QPPESGAPASPQSGAPAAPQSGTPGRPGAQPRPYPQDPPPSP
MUL_1725|M.ulcerans_Agy99 --------QPPESSAPASPQSGAPAAPQSGTPGRPGAQPRPYPQDPPPSP
MLBr_00487|M.leprae_Br4923 -----------------TLPNFAPMPPD-----HPGAQPRPYLQDP----
MAV_2986|M.avium_104 ----------------------------------PTVRIAPLPVRP----
Mflv_3816|M.gilvum_PYR-GCK --APSPAPEPPADPAAP-IPPGTPAGPGGMPADDEN-LSLADQIKQEKLR
Mvan_2583|M.vanbaalenii_PYR-1 --APTPPPGPSPAPGPT-PPP----APGTAPPADQD-VPLATRIQDEKRL
TH_1363|M.thermoresistible__bu --------------------------------------------------
MSMEG_2961|M.smegmatis_MC2_155 --APTPG-EPTPAPAPE-PAPGENPPAAPAPGADGDKADLAQRIATAKQW
MAB_2880c|M.abscessus_ATCC_199 --TTPPPPPPATQPATP-NATTAPAPPADLPPKPGSGEERKQLIDFEKQI
Mb2618c|M.bovis_AF2122/97 --APSPNPTSPASPPPA--------PPAEAPAT-DPRKDLAERIAQEKKL
Rv2587c|M.tuberculosis_H37Rv --APSPNPTSPASPPPA--------PPAEAPAT-DPRKDLAERIAQEKKL
MMAR_2120|M.marinum_M APAPSPAPTGSPAPPATGAQQPADLPPGEEPALPDPRKDLAERIAQEKKW
MUL_1725|M.ulcerans_Agy99 APAPSPAPTGSPAPPATGAQQPADLPPGEEPALPDPRKDLAERIAQEKKW
MLBr_00487|M.leprae_Br4923 --TSSPSSDPMPSPVPTGAALPGEVPSVEQPAPPDPRKDLAERIAEEKKW
MAV_2986|M.avium_104 --------VTKSQPTTP---------------------------------
Mflv_3816|M.gilvum_PYR-GCK RQSSDQMIQILAMQLQASQCGQ-EDVLAGNDDPNLPLITCSQD---GTTV
Mvan_2583|M.vanbaalenii_PYR-1 RQSTEQAIQILALQFQATRCGQ-EDVLAGNDDPNLPLVTCSQD---GNEV
TH_1363|M.thermoresistible__bu -------------------------VLAGNDDPELPLITCSTD---GQTV
MSMEG_2961|M.smegmatis_MC2_155 RQSTDPTMQILGLQVQANLCGE-DDILAGNDDPNLPLITCSTD---GSTV
MAB_2880c|M.abscessus_ATCC_199 RQSEDPRIQMLALQVQASRCYDPDDPLAGNDDPNLPLVTCGDDSQGGKAA
Mb2618c|M.bovis_AF2122/97 RQSTNQYMQMVALQFQATRCES-DDILAGNDDPKLPLVTCSTD---HKTA
Rv2587c|M.tuberculosis_H37Rv RQSTNQYMQMVALQFQATRCES-DDILAGNDDPKLPLVTCSTD---HKTA
MMAR_2120|M.marinum_M RQSTNQYIQMVALQFEATQCGK-DDILAGNDDPKLPLVTCSTD---HKTA
MUL_1725|M.ulcerans_Agy99 RQSTNQYIQMVALQFEATQCGK-DDILAGNDDPKLPLVTCSTD---HKTA
MLBr_00487|M.leprae_Br4923 RQSTKQSIQFLALQFESTHCDK-DDILAGNDDPNLPLATCSTD---HNMA
MAV_2986|M.avium_104 ----------------AVKCPAIDPTVP--VPPTDGLTTCDIA---RATV
:. * * **. .
Mflv_3816|M.gilvum_PYR-GCK YLLDKSIIAGEEIANATSGLN-QQAGEYVVDLEFKDQGSKTWAEFTAAN-
Mvan_2583|M.vanbaalenii_PYR-1 YLLDKSIISGEQIANASSGLN-QQAGEYVVDVEFKSDAAKVWADFTAAN-
TH_1363|M.thermoresistible__bu YLLNKSIISGEQIENASSGRDPQRGGEYVVDLQFKGDATDIWADFTAAN-
MSMEG_2961|M.smegmatis_MC2_155 YLLNKSIMSGEEIKNATSGLD-QQQGQYVVDVEFKSGGAQTWADFTAAN-
MAB_2880c|M.abscessus_ATCC_199 YLLDKSIISGEEIKDASSGLD-QQRGIYVVSMEFKPTGAKVWADYTSAHW
Mb2618c|M.bovis_AF2122/97 YLLAPSIISGDQIQNATSGMD-QRGIGYVVDLQFKGPAANIWADYTAAH-
Rv2587c|M.tuberculosis_H37Rv YLLAPSIISGDQIQNATSGMD-QRGIGYVVDLQFKGPAANIWADYTAAH-
MMAR_2120|M.marinum_M YLLAPSIISGDQIQNATSGMD-QRSIGYVVDLQFKSQAANTWADYTAAH-
MUL_1725|M.ulcerans_Agy99 YLLAPSIISGDQIQNATSGMD-QRSIGYVVDLQFKSQAANTWADYTAAH-
MLBr_00487|M.leprae_Br4923 YLLAPSIISGDQIQNSTSGMN-QRGVGYVVDLQFKSAAADVWADFTAAH-
MAV_2986|M.avium_104 YTLGPEAMQLG-LINVDPPKS-LTADYYEVTLVLDPASASAWAAFTGEH-
* * . : : : . . * * : :. .:. ** :*. :
Mflv_3816|M.gilvum_PYR-GCK -VGVQTAFVLDSKVVSAPVINEPIPGGKTQITG---QFTQDTARELANVL
Mvan_2583|M.vanbaalenii_PYR-1 -VGTQTAFVLDSQVVSAPVIQEAIPGGRTQITG---QFTQTTARELANVL
TH_1363|M.thermoresistible__bu -VGTQTAFVLDSKVVSAPQIQEPIPGGRTQITG---RFNAETAKELANVL
MSMEG_2961|M.smegmatis_MC2_155 -VGTQTAFTLDSKVVSAPEIREAIPGGNTQITG---QFTADSAKELANVL
MAB_2880c|M.abscessus_ATCC_199 QQGTQTAFTLDSKVISAPAIREPIPGGKTEISG---QFTSDSAKQLAAAL
Mb2618c|M.bovis_AF2122/97 -IGTQTAFTLDSQVVSAPQIQEAIPGGRTQISGGDPPFTAATARQLANVL
Rv2587c|M.tuberculosis_H37Rv -IGTQTAFTLDSQVVSAPQIQEAIPGGRTQISGGDPPFTAATARQLANVL
MMAR_2120|M.marinum_M -IGTQTAFTLDSQVVSAPQILEAIPGGRTQISGGEPPFSASTARQLANVL
MUL_1725|M.ulcerans_Agy99 -IGTQTAFTLDSQVVSAPQILEAIPGGRTQISGGEPPFSASTARQLANVL
MLBr_00487|M.leprae_Br4923 -IGTQTAFTLDSEVVSVPVINEAILGGRTQISGGDPPFTAATARQLANVL
MAV_2986|M.avium_104 -PKDHIAFIRDNLVVEAPIIEEQVTSGRIALTT----QTAQGAAQLAQLV
: ** *. *:..* * * : .*. :: . * :** :
Mflv_3816|M.gilvum_PYR-GCK KYGSLPLSFESSEAETVSATLGLSSLRAGLIAGAVGLAAVLLYSLLYYRA
Mvan_2583|M.vanbaalenii_PYR-1 KYGSLPLSFESSEAETVSATLGLSSLRAGLIAGVVGLVAVLLYSLLYYRV
TH_1363|M.thermoresistible__bu KYGSLPLSFEASEAETVSPTLGLNSLRAGLIAGAVGLAAVLLYSLLYYRL
MSMEG_2961|M.smegmatis_MC2_155 KYGSLPLSFESSEAETVSATLGLSSLRAGLIAGAIGLAAVLLYSLLYYRV
MAB_2880c|M.abscessus_ATCC_199 KYGSLPLSFESSDAQTVSATLGLTSLKAGLIAGAIGLAIVLLYSLIYYRV
Mb2618c|M.bovis_AF2122/97 KYGSLPLSFEPSEAQTVSATLGLSSLRAGMIAGAIGLLLVLVYSLLYYRV
Rv2587c|M.tuberculosis_H37Rv KYGSLPLSFEPSEAQTVSATLGLSSLRAGMIAGAIGLLLVLVYSLLYYRV
MMAR_2120|M.marinum_M KYGSLPLSFESSEAQTVSATLGLTSLRAGLIAGAIGLALVLLYSLLYYRV
MUL_1725|M.ulcerans_Agy99 KYGSLPLSFESSEAQTVSATLGLTSLRAGLIAGAIGLALVLLYSLLYYRV
MLBr_00487|M.leprae_Br4923 KYGSLPLSFEPSEAQTVSATLGLTSLRAGLIAGAIGLSLVLLYSLLYYRV
MAV_2986|M.avium_104 GRPG----------------------------------------------
.
Mflv_3816|M.gilvum_PYR-GCK LGVLIALSLVASGAMVFAILVLLGRYINYTLDLAGIAGLIIGIGMTADSF
Mvan_2583|M.vanbaalenii_PYR-1 LGVLIALSLTASGAMVFAILVLLGRYISYTLDLAGIAGLIIGIGMTADSF
TH_1363|M.thermoresistible__bu LGVLTALSLVAAGALVYAVLVLLGRYINYTLDLAGVAGLIIGIGTTADSF
MSMEG_2961|M.smegmatis_MC2_155 LGLLVALSLVAAGAVVYAILVLLGRYIGYTLDLAGIAGLIIGIGTTADSF
MAB_2880c|M.abscessus_ATCC_199 LGLLTALSLVASGAMVFAILVLLGRYISYTLDLAGIAGLIIGIGTTADSF
Mb2618c|M.bovis_AF2122/97 LGLLTALSLVASGSMVFAILVLLGRYINYTLDLAGIAGLIIGIGTTADSF
Rv2587c|M.tuberculosis_H37Rv LGLLTALSLVASGSMVFAILVLLGRYINYTLDLAGIAGLIIGIGTTADSF
MMAR_2120|M.marinum_M LGLLTALSLIASGAMVFAILVLLGRYINYTLDLAGIAGLIIGIGTTADSF
MUL_1725|M.ulcerans_Agy99 LGLLTALSLIASGAMVFAILVLLGRYINYTLDLAGIAGLIIGIGTTADSF
MLBr_00487|M.leprae_Br4923 LGLLTAFSLFCSGTIIFAILVLLGRYINYTLDLAGIAGLIIGIGTTADSF
MAV_2986|M.avium_104 --------------------------------------------------
Mflv_3816|M.gilvum_PYR-GCK VVFFERIKDEIREGRSFRSAVPRGWARARKTILSGNAVTFLAAAVLYFLA
Mvan_2583|M.vanbaalenii_PYR-1 VVFFERIKDEIREGRSFRSAVPRGWARARKTIVSGNAVTLLAAAVLYFLA
TH_1363|M.thermoresistible__bu VVFFERIKDEIREGRSFRSAVPRGWARARKTILSGNAVTFLAAAVLYFLA
MSMEG_2961|M.smegmatis_MC2_155 VVFFERIKDEIREGRSFRSAVPRGWVRARKTIVSGNAVTFLAAAVLYVLA
MAB_2880c|M.abscessus_ATCC_199 VVFFERIKDEIREGRSYRSAVPRGWARARKTILSGNAVTLLAAVVLYILA
Mb2618c|M.bovis_AF2122/97 VVFFERIKDEIREGRSFRSAVPRGWARARKTIVSGSAVTFLAAAVLYFLA
Rv2587c|M.tuberculosis_H37Rv VVFFERIKDEIREGRSFRSAVPRGWARARKTIVSGNAVTFLAAAVLYFLA
MMAR_2120|M.marinum_M VVFFERIKDEIREGRSFRSAVPRGWARARKTIVSGNAVTFLAAAVLYFLA
MUL_1725|M.ulcerans_Agy99 VVFFERIKDEIREGRSFRSAVPRGWARARKTIVSGNAVTFLAAAVLYFLA
MLBr_00487|M.leprae_Br4923 VVFFERIKDEIREGRSFRSAVPRGWVRARKTIVSGNAVTFLAAAVLHFLA
MAV_2986|M.avium_104 --------------------------------------------------
Mflv_3816|M.gilvum_PYR-GCK VGQVKGFAFTLGLTTILDVVVVFLVTWPLVYLASKSPLWAKPSLNGLGAV
Mvan_2583|M.vanbaalenii_PYR-1 VGQVKGFAFTLGLTTILDIVVVFLVTWPLVYMASKSTLWAKPSLNGLGAV
TH_1363|M.thermoresistible__bu IGQVKGFAFTLGLTTIFDVMVVFLVTWPLVYLASKSPTLAKPSLNGLGAV
MSMEG_2961|M.smegmatis_MC2_155 IGQVKGFAFTLGLTTILDLVVVFLVTWPLVYLASKSPTMAKPKLNGLGAV
MAB_2880c|M.abscessus_ATCC_199 IGQVKGFAFTLGLTTILDVVVVFLVTWPLVYLSSKSATLSKPAYNGLGAV
Mb2618c|M.bovis_AF2122/97 IGQVKGFAFTLGLTTILDLVVVFLVTWPLVYLASKSSLLAKPAYNGLGAV
Rv2587c|M.tuberculosis_H37Rv IGQVKGFAFTLGLTTILDLVVVFLVTWPLVYLASKSSLLAKPAYNGLGAV
MMAR_2120|M.marinum_M IGQVKGFAFTLGLTTILDIVVVFLVTWPLVYLASKSPRLAKPAYNGLGAV
MUL_1725|M.ulcerans_Agy99 IGQVKGFAFTLGLTTILDIVVVFLVTWPLVYLASKSPRLAKPAYNGLGAV
MLBr_00487|M.leprae_Br4923 IGQVKGFAFTLGLTTILDLVVVFLVTWPLVYLASKSPLLARPAYNGLGAV
MAV_2986|M.avium_104 --------------------------------------------------
Mflv_3816|M.gilvum_PYR-GCK QQIARERR-------AAATAAGRG-
Mvan_2583|M.vanbaalenii_PYR-1 QQIARERR-------AAASAAGRG-
TH_1363|M.thermoresistible__bu QQIARERR-------AARATTGQGI
MSMEG_2961|M.smegmatis_MC2_155 QQIARERRE------VSHATAGRG-
MAB_2880c|M.abscessus_ATCC_199 QQIARERKA------AAHA------
Mb2618c|M.bovis_AF2122/97 QQVARERRA--------MARTGRG-
Rv2587c|M.tuberculosis_H37Rv QQVARERRA--------MARTGRG-
MMAR_2120|M.marinum_M QQVARERRASDSRTRSGIAKTGRG-
MUL_1725|M.ulcerans_Agy99 QQVARERRASDSRTRSGIAKTGRE-
MLBr_00487|M.leprae_Br4923 QQVARERRAS--------AKTGRG-
MAV_2986|M.avium_104 -------------------------