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MTNAIAPTPTAARPTTQSDDSYEDVVEMFLELRRMPAESHEYRRQRERIVARCLPLADHVASHFARRGEG LDDLVQVARLGLMNAVNRFDPAKGPSFIGFAVPTMMGEVRRYFRDYSWGMRVPRRLRELHVQISRTTADL AQQLGRAPNAGELSQVLEVPREEIVECLVAGDAYRLDSLDAPQGADSSGTPRSVADSVGDIDPQIEHITN REALRVLVATLPHREREVLRMRFFESMTQSQIAERIGVSQMQVSRILANTLRCLRDQLE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2963 | - | - | 100% (269) | RNA polymerase sigma factor SigF |
| M. avium 104 | MAV_4256 | - | 3e-74 | 57.44% (242) | RNA polymerase sigma factor SigF |
| M. avium 104 | MAV_3595 | - | 8e-17 | 26.43% (227) | RNA polymerase sigma factor |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3314c | sigF | 1e-77 | 54.96% (262) | RNA polymerase sigma factor SigF |
| M. gilvum PYR-GCK | Mflv_4789 | - | 7e-80 | 56.11% (262) | RNA polymerase sigma factor SigF |
| M. tuberculosis H37Rv | Rv3286c | sigF | 1e-77 | 54.96% (262) | RNA polymerase sigma factor SigF |
| M. leprae Br4923 | MLBr_01022 | rpoT | 3e-17 | 26.43% (227) | RNA polymerase sigma factor |
| M. abscessus ATCC 19977 | MAB_2511 | - | 6e-83 | 58.85% (260) | RNA polymerase sigma factor SigF |
| M. marinum M | MMAR_1248 | sigF | 1e-76 | 54.96% (262) | alternate RNA polymerase sigma factor SigF |
| M. smegmatis MC2 155 | MSMEG_1804 | - | 2e-77 | 57.66% (248) | RNA polymerase sigma factor SigF |
| M. thermoresistible (build 8) | TH_0241 | sigF | 2e-80 | 60.66% (244) | ALTERNATE RNA POLYMERASE SIGMA FACTOR SIGF |
| M. ulcerans Agy99 | MUL_2640 | sigF | 1e-76 | 54.96% (262) | RNA polymerase sigma factor SigF |
| M. vanbaalenii PYR-1 | Mvan_1660 | - | 1e-77 | 56.86% (255) | RNA polymerase sigma factor SigF |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2963|M.avium_104 --------------------------------------------------
MAB_2511|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3314c|M.bovis_AF2122/97 --------------------------------------------------
Rv3286c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1248|M.marinum_M --------------------------------------------------
MUL_2640|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4789|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1660|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0241|M.thermoresistible__bu --------------------------------------------------
MSMEG_1804|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01022|M.leprae_Br4923 MEQSRRVPPLQWLSAVARPIARVLTLISTPTFDIADTFGYACPNPPEVSP
MAV_2963|M.avium_104 --------------------------------------------------
MAB_2511|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3314c|M.bovis_AF2122/97 --------------------------------------------------
Rv3286c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1248|M.marinum_M --------------------------------------------------
MUL_2640|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4789|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1660|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0241|M.thermoresistible__bu --------------------------------------------------
MSMEG_1804|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01022|M.leprae_Br4923 TEGVYVVATKTSPATGQPVKRTATKTPATPAKRSTTKAANGSAPTKRATS
MAV_2963|M.avium_104 --------------------------------------------------
MAB_2511|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3314c|M.bovis_AF2122/97 --------------------------------------------------
Rv3286c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1248|M.marinum_M --------------------------------------------------
MUL_2640|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4789|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1660|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0241|M.thermoresistible__bu --------------------------------------------------
MSMEG_1804|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01022|M.leprae_Br4923 TASRATKSTTPPKASGASDAAKKARTSVKSVDTKAPSAQDHTTKASAAKD
MAV_2963|M.avium_104 --------------------------------------------------
MAB_2511|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3314c|M.bovis_AF2122/97 --------------------------------------------------
Rv3286c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1248|M.marinum_M --------------------------------------------------
MUL_2640|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4789|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1660|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0241|M.thermoresistible__bu --------------------------------------------------
MSMEG_1804|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01022|M.leprae_Br4923 TLNDPEATLNTLDSDATADDLDAEPDLDVEPSEDIDIDIEAADLGLDDLE
MAV_2963|M.avium_104 --------------------------------------------------
MAB_2511|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3314c|M.bovis_AF2122/97 --------------------------------------------------
Rv3286c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1248|M.marinum_M --------------------------------------------------
MUL_2640|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4789|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1660|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0241|M.thermoresistible__bu --------------------------------------------------
MSMEG_1804|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01022|M.leprae_Br4923 DDDVVTDIEPGETEDGEATAATKTDEASTDDDEEIVEPTEKDKASGDFVW
MAV_2963|M.avium_104 ----------------MTNAIAPTPT---AARPTT-QSDDSYEDVVE---
MAB_2511|M.abscessus_ATCC_1997 ----------------MECPVDVPETGHSQVKPRVGRPTDDYADVPD---
Mb3314c|M.bovis_AF2122/97 ----------------MTARAAGGSAS---------RANE-YADVPE---
Rv3286c|M.tuberculosis_H37Rv ----------------MTARAAGGSAS---------RANE-YADVPE---
MMAR_1248|M.marinum_M ----------------MTSRTAGGSSS---------RPNE-YADVPE---
MUL_2640|M.ulcerans_Agy99 ----------------MTSRTAGGSSS---------RPNE-YADVPE---
Mflv_4789|M.gilvum_PYR-GCK ----------------MTRSSSQGSS----------RSNSEYSDVAD---
Mvan_1660|M.vanbaalenii_PYR-1 ----------------MTRSSSQGSSS---------RSGSEYADVAP---
TH_0241|M.thermoresistible__bu --------------------------------------------------
MSMEG_1804|M.smegmatis_MC2_155 ----------------MTS---------------------EYADVLD---
MLBr_01022|M.leprae_Br4923 DEDESEALRQARKDAELTASADSVRAYLKQIGKVALLNAEEEVELAKRIE
MAV_2963|M.avium_104 -------MFLELRRMPAESHEYRRQ------------RERIVARCLPLAD
MAB_2511|M.abscessus_ATCC_1997 -------MFRSLAGLAEHSDAYQRK------------HEEIVTRCLPLAD
Mb3314c|M.bovis_AF2122/97 -------MFRELVGLPAGSPEFQRH------------RDKIVQRCLPLAD
Rv3286c|M.tuberculosis_H37Rv -------MFRELVGLPAGSPEFQRH------------RDKIVQRCLPLAD
MMAR_1248|M.marinum_M -------MFRELATFDADSPNFQRH------------RDTIVERCLPLAD
MUL_2640|M.ulcerans_Agy99 -------MFRELATFDADSPNFQRH------------RDTIVERCLPLAD
Mflv_4789|M.gilvum_PYR-GCK -------MFRELAELEEGSAAFQRQ------------RDRIVERCLPLAD
Mvan_1660|M.vanbaalenii_PYR-1 -------MFRELAELEEGTAAFQRQ------------RDRIVERCLPLAD
TH_0241|M.thermoresistible__bu -------MFRELRKLPAESKEFQRQ------------RDRIVERCLPLAD
MSMEG_1804|M.smegmatis_MC2_155 -------MFRELAGTTEGSPSYVRQ------------REKIVERCLPLAD
MLBr_01022|M.leprae_Br4923 AGLYATQLMTELSERGTKLPTAQRRDMMWICRDGDRAKNHLLEANLRLVV
:: .* *: :: :: * *.
MAV_2963|M.avium_104 HVASHFARRGEGLDDLVQVARLGLMNAVNRFDPAKGPSFIGFAVPTMMGE
MAB_2511|M.abscessus_ATCC_1997 NVARHFDRRGEDLEDLIQVARVGLLNAVNRFDPEKGASFLGFAVPTMMGE
Mb3314c|M.bovis_AF2122/97 HIARRFEGRGEPRDDLIQVARVGLVNAAVRFDVKTGSDFVSFAVPTIMGE
Rv3286c|M.tuberculosis_H37Rv HIARRFEGRGEPRDDLIQVARVGLVNAAVRFDVKTGSDFVSFAVPTIMGE
MMAR_1248|M.marinum_M HIARRFEGRGEPRDDLVQVARVGLVNAVVRFDVETGSDFVSFAVPTIMGE
MUL_2640|M.ulcerans_Agy99 HIARRFEGRGEPRDDLVQVARVGLVNAVVRFDVETGSDFVSFAVPTIMGE
Mflv_4789|M.gilvum_PYR-GCK HIARRFDGRGEPRDDLVQVARVGLVNAVIRFDVTAGSDFVSFAVPTIMGE
Mvan_1660|M.vanbaalenii_PYR-1 HIARRFDGRGEPRDDLVQVARVGLVNAVIRFDVNAGSDFVSFAVPTIMGE
TH_0241|M.thermoresistible__bu HIARRFDGRGEARDDLVQVARVGLVNAVIRFDVETGSDFVSFAVPTIMGE
MSMEG_1804|M.smegmatis_MC2_155 HIARRFDGRGEPREDLVQVARVGLVNAVNRFDVEAGSDFVSFAVPTIMGE
MLBr_01022|M.leprae_Br4923 SLAKRYTGRGMAFLDLIQEGNLGLIRAVEKFDYTKGYKFSTYATWWIRQA
:* :: ** **:* ..:**:.*. :** * .* :*. :
MAV_2963|M.avium_104 VRRYFRDYSWGMRVPRRLRELHVQISRTTADLAQQLGRAPNAGELSQVLE
MAB_2511|M.abscessus_ATCC_1997 VRRHFRDHGWSLHVPRAIRDRHAQISRATAELTQELQRAPTAGELAAELG
Mb3314c|M.bovis_AF2122/97 VRRHFRDNSWSVKVPRRLKELHLRLGTATADLSQRLGRAPSASELAAELG
Rv3286c|M.tuberculosis_H37Rv VRRHFRDNSWSVKVPRRLKELHLRLGTATADLSQRLGRAPSASELAAELG
MMAR_1248|M.marinum_M VRRHFRDNSWSVKVPRRLKELHLRLGAATAELSQRLGRAPTATELAAELE
MUL_2640|M.ulcerans_Agy99 VRRHFRDNSWSVKVPRRLKELHLRLGAATAELSQRLGRAPTATELAAELE
Mflv_4789|M.gilvum_PYR-GCK VRRHFRDNSWSVKVPRRLKELHLRLGAATAELSQRLGRAPTPSELAAELE
Mvan_1660|M.vanbaalenii_PYR-1 VRRHFRDNSWSVKVPRRLKELHLRLGAATAELSQRLGRAPTATELAAELE
TH_0241|M.thermoresistible__bu VRRHFRDNSWSVKVPRRLKELHLRLGAATAELSQRLGRAPTASELAEELE
MSMEG_1804|M.smegmatis_MC2_155 VRRHFRDNSWSVKVPRRLKELHLRLGAATAELSQRLGRAPTASELAHELD
MLBr_01022|M.leprae_Br4923 ITRAMADQARTIRIPVHMVEVINKLGRIQRELLQDLGREPTPEELAKEMD
: * : * . :::* : : ::. :* * * * *.. **: :
MAV_2963|M.avium_104 VPREEIVECLVAGDAYRLDSLDAPQGADSSGTPRSVADSVGDIDPQIEHI
MAB_2511|M.abscessus_ATCC_1997 IDREEVVESLIAADAYQPQSIEAPLSHGDQES-KHLSDLLGNEDPALEHV
Mb3314c|M.bovis_AF2122/97 MDRAEVIEGLLAGSSYHTLSIDSGGG-S-DDDARAITDTLGDVDAGLDQI
Rv3286c|M.tuberculosis_H37Rv MDRAEVIEGLLAGSSYHTLSIDSGGG-S-DDDARAITDTLGDVDAGLDQI
MMAR_1248|M.marinum_M MDRAEVVEGLVAGSSYNTLSIDSGSG-SEDDDARAIADTLGDMDAGLDRI
MUL_2640|M.ulcerans_Agy99 MDRAEVVEGLVAGSSYNTLSIDSGSG-SEDDDARAIADTLGDMDAGLDRI
Mflv_4789|M.gilvum_PYR-GCK MDRDEVVEGLVAGSSYNTLSIDSGGG-SGNEDAPAIADTLGDVDLTLDQI
Mvan_1660|M.vanbaalenii_PYR-1 MDRDEVVEGLVAGSSYNTLSIDSGG--SGNEDAPAIADTLGDVDLSLDQI
TH_0241|M.thermoresistible__bu MDRDEVIEGLVAGSSYNTLSIDSGGSGSGTEDAPAIADTLGDVDTGLDQI
MSMEG_1804|M.smegmatis_MC2_155 MDREEVVEGLIAGSSYNTLSIDSGGG--GDEEAPAIVDTLGDLDMGLDQI
MLBr_01022|M.leprae_Br4923 ITPEKVLE--IQQYAREPISLDQTIG---DEGDSQLGDFIEDSEAVVAVD
: :::* : : . *:: : * : : : :
MAV_2963|M.avium_104 TN-----REALRVLVATLPHREREVLRMRFFES----MTQSQIAERIGVS
MAB_2511|M.abscessus_ATCC_1997 TN-----REAVRPLLANLPLRERTVLELRFFKG----MTQSQIAAQIGVS
Mb3314c|M.bovis_AF2122/97 EN-----REVLRPLLEALPERERTVLVLRFFDS----MTQTQIAERVGIS
Rv3286c|M.tuberculosis_H37Rv EN-----REVLRPLLEALPERERTVLVLRFFDS----MTQTQIAERVGIS
MMAR_1248|M.marinum_M ED-----RESLRPLLEALPERERTVLVLRFFDS----MTQTQIAERVGIS
MUL_2640|M.ulcerans_Agy99 ED-----RESLRPLLEALPERERTVLVLRFFDS----MTQTQIAERVGIS
Mflv_4789|M.gilvum_PYR-GCK EN-----REALRPLLAALPERERTVLVLRFFES----MTQTQIAERVGIS
Mvan_1660|M.vanbaalenii_PYR-1 EN-----REALRPLLAALPERERTVLALRFFES----MTQTQIAERVGIS
TH_0241|M.thermoresistible__bu EN-----REALRPLLAALPERERTVLVLRFFES----LTQTQIAERVGIS
MSMEG_1804|M.smegmatis_MC2_155 DN-----RESLRPLLASLPERERTVLVLRFFES----MTQTQIAERVGIS
MLBr_01022|M.leprae_Br4923 AVSFTLLQDQLQSVLETLSEREAGVVRLRFGLTDGQPRTLDEIGQVYGVT
:: :: :: *. ** *: :** * :*. *::
MAV_2963|M.avium_104 QMQVSRILANTLRCLRDQLE---------
MAB_2511|M.abscessus_ATCC_1997 QMHVSRILSDTLRYLREQMA---------
Mb3314c|M.bovis_AF2122/97 QMHVSRLLAKSLARLRDQLE---------
Rv3286c|M.tuberculosis_H37Rv QMHVSRLLAKSLARLRDQLE---------
MMAR_1248|M.marinum_M QMHVSRLLAKSLARLRDQLE---------
MUL_2640|M.ulcerans_Agy99 QMHVSRLLAKSLARLRDQLE---------
Mflv_4789|M.gilvum_PYR-GCK QMHVSRLLAKSLTRLRDQLE---------
Mvan_1660|M.vanbaalenii_PYR-1 QMHVSRLLAKSLARLRDQLE---------
TH_0241|M.thermoresistible__bu QMHVSRLLAKSLARLRDQLE---------
MSMEG_1804|M.smegmatis_MC2_155 QMHVSRLLAKSLARLRDQLQ---------
MLBr_01022|M.leprae_Br4923 RERIRQIESKTMSKLRHPSRSQVLRDYLD
: :: :: :.:: **.