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MSPGDGAGGQTTTTTALRVGVQAPVREFGPLTRQMFVRYAGASGDFNPMHYDDQLARSAGYPSVFAQGMF SAALLAGFATDWLGAGSVRRFGVRFREQVWPGDVLTCSGTVTAVSAEPDAERVIVELTATRQTGGVAITG TAEFVNPRNAARCGAGDADRP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2649 | - | - | 100% (161) | MaoC like domain-containing protein |
| M. avium 104 | MAV_1946 | - | 5e-56 | 84.00% (125) | MaoC family protein |
| M. avium 104 | MAV_4526 | - | 5e-18 | 40.15% (132) | (3R)-hydroxyacyl-ACP dehydratase subunit HadB |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0655 | - | 4e-19 | 39.55% (134) | (3R)-hydroxyacyl-ACP dehydratase subunit HadB |
| M. gilvum PYR-GCK | Mflv_5120 | - | 9e-16 | 35.82% (134) | (3R)-hydroxyacyl-ACP dehydratase subunit HadB |
| M. tuberculosis H37Rv | Rv0636 | - | 4e-19 | 39.55% (134) | (3R)-hydroxyacyl-ACP dehydratase subunit HadB |
| M. leprae Br4923 | MLBr_01909 | - | 2e-19 | 40.30% (134) | (3R)-hydroxyacyl-ACP dehydratase subunit HadB |
| M. abscessus ATCC 19977 | MAB_2055 | - | 3e-30 | 47.24% (127) | MaoC-like dehydratase |
| M. marinum M | MMAR_0969 | - | 2e-19 | 41.04% (134) | hypothetical protein MMAR_0969 |
| M. smegmatis MC2 155 | MSMEG_6754 | - | 1e-15 | 37.50% (144) | MaoC like domain-containing protein |
| M. thermoresistible (build 8) | TH_1867 | - | 6e-16 | 36.09% (133) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0721 | - | 1e-19 | 41.04% (134) | (3R)-hydroxyacyl-ACP dehydratase subunit HadB |
| M. vanbaalenii PYR-1 | Mvan_3988 | - | 1e-18 | 39.37% (127) | dehydratase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0969|M.marinum_M --------------------------------------------------
MUL_0721|M.ulcerans_Agy99 --------------------------------------------------
Mb0655|M.bovis_AF2122/97 --------------------------------------------------
Rv0636|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01909|M.leprae_Br4923 --------------------------------------------------
Mflv_5120|M.gilvum_PYR-GCK --------------------------------------------------
TH_1867|M.thermoresistible__bu --------------------------------------------------
MSMEG_6754|M.smegmatis_MC2_155 MTAPADTSTLESRVGHYYQMEDTYLVGREKVREFARAVQDYHPAHWNLAT
MAV_2649|M.avium_104 --------------------------------------------------
MAB_2055|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3988|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0969|M.marinum_M --------------------------------------------------
MUL_0721|M.ulcerans_Agy99 --------------------------------------------------
Mb0655|M.bovis_AF2122/97 --------------------------------------------------
Rv0636|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01909|M.leprae_Br4923 --------------------------------------------------
Mflv_5120|M.gilvum_PYR-GCK --------------------------------------------------
TH_1867|M.thermoresistible__bu --------------------------------------------------
MSMEG_6754|M.smegmatis_MC2_155 AADLGHPGLIAPLTFTSAPAMACNQRMFESVVVGYDMYLQTEEVFEQHRP
MAV_2649|M.avium_104 --------------------------------------------------
MAB_2055|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3988|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0969|M.marinum_M --------------------------------------------------
MUL_0721|M.ulcerans_Agy99 --------------------------------------------------
Mb0655|M.bovis_AF2122/97 --------------------------------------------------
Rv0636|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01909|M.leprae_Br4923 --------------------------------------------------
Mflv_5120|M.gilvum_PYR-GCK --------------------------------------------------
TH_1867|M.thermoresistible__bu --------------------------------------------------
MSMEG_6754|M.smegmatis_MC2_155 IVEGDELSIDIELTSVRRIAGRDLITVTNTFTDTAGEVVHTLHTTVVGIT
MAV_2649|M.avium_104 --------------------------------------------------
MAB_2055|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3988|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0969|M.marinum_M -------------------------------------------MALR---
MUL_0721|M.ulcerans_Agy99 -------------------------------------------MALR---
Mb0655|M.bovis_AF2122/97 -------------------------------------------MALR---
Rv0636|M.tuberculosis_H37Rv -------------------------------------------MALR---
MLBr_01909|M.leprae_Br4923 -------------------------------------------MARR---
Mflv_5120|M.gilvum_PYR-GCK -------------------------------------------MALR---
TH_1867|M.thermoresistible__bu -------------------------------------------MALR---
MSMEG_6754|M.smegmatis_MC2_155 AEDVDPAIRPAVQGVMMHGINMLGVEETNAPYEKTVRPEGELRIAQGGAT
MAV_2649|M.avium_104 --------------------------------------------MSPGDG
MAB_2055|M.abscessus_ATCC_1997 --------------------------------------------MT----
Mvan_3988|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0969|M.marinum_M ------EFSSVNVGDQLP-ERTYPLTRQDLVNYAGVSGDLNPIHWDDEIA
MUL_0721|M.ulcerans_Agy99 ------EFSSVNVGDQLP-ERTYPLTRQDLVNYAGVSGDLNPIHWDDEIA
Mb0655|M.bovis_AF2122/97 ------EFSSVKVGDQLP-EKTYPLTRQDLVNYAGVSGDLNPIHWDDEIA
Rv0636|M.tuberculosis_H37Rv ------EFSSVKVGDQLP-EKTYPLTRQDLVNYAGVSGDLNPIHWDDEIA
MLBr_01909|M.leprae_Br4923 ------EFSSVKVGDLLP-EKTYPLTRQDLVNYAGVSGDLNPIHWDDEIA
Mflv_5120|M.gilvum_PYR-GCK ------EFSSVKVGDLLP-EKVIPLTRADLVNYAGVSGDLNPIHWDDEIA
TH_1867|M.thermoresistible__bu ------KFDSVKVGDKLP-EKVIPLTRADLVNYAGVSGDLNPIHWDDEIA
MSMEG_6754|M.smegmatis_MC2_155 RTPTSLNFDDLKVGEELP-VHTARLSRGDLVNYAGVAGDANPLHWDENIA
MAV_2649|M.avium_104 AGGQTTTTTALRVGVQAPVREFGPLTRQMFVRYAGASGDFNPMHYDDQLA
MAB_2055|M.abscessus_ATCC_1997 ---TSPAPVALAAGDEMPSSQFGPLTRSHIVRYAGSGGDFNPIHHDEEFA
Mvan_3988|M.vanbaalenii_PYR-1 ----MIGIDSVAVGDELPPLQAPDVSRLTLALFAGASGDHNPMHVDLDEA
: .* * . ::* :. :** .** **:* * : *
MMAR_0969|M.marinum_M KLVGLDTAIAHGMLTMGIGGGYVTSWVGDPGAVTEYNVRFTAVVPVPNDG
MUL_0721|M.ulcerans_Agy99 KLVGLDTAIAHGMLTMGIGGGYVTSWVGDPGAVTEYNVRFTAVVPVPNDG
Mb0655|M.bovis_AF2122/97 KVVGLDAAIAHGMLTMGIGGGYVTSWVGDPGAVTEYNVRFTAVVPVPNDG
Rv0636|M.tuberculosis_H37Rv KVVGLDTAIAHGMLTMGIGGGYVTSWVGDPGAVTEYNVRFTAVVPVPNDG
MLBr_01909|M.leprae_Br4923 KVVGLDTAIAHGMLTMGIGGGYVTSWVGDPGAVIEYNVRFTAVVPVPNDG
Mflv_5120|M.gilvum_PYR-GCK KQVGLDTAIAHGMLTMGLGGGYVTEWVGDPAAVTEYNVRFTAVVPVPNDG
TH_1867|M.thermoresistible__bu KQVGLDTAIAHGMLTMGMGGGYITEWVGDPAAVTEYNVRFTAVVPVPNDG
MSMEG_6754|M.smegmatis_MC2_155 KLAGQPDVIAHGMLTMGLGAGFVSSWSGDPGAITRYAVRLSQPAVVPAEG
MAV_2649|M.avium_104 RSAGYPSVFAQGMFSAALLAGFATDWLG-AGSVRRFGVRFREQVWP----
MAB_2055|M.abscessus_ATCC_1997 RAAGMPGVFGMGLLHGGVLAQRLTAWVG-LANIRSFRIRFTGQVWP----
Mvan_3988|M.vanbaalenii_PYR-1 RSAGLPDVFAHGMLSMAYLGRLITDWVP-QERLRTFRVRFAAITPV----
: .* .:. *:: . . : * : : :*: .
MMAR_0969|M.marinum_M KGAELVFNGRVKSVDPDSK----SVTIALTATTGGKKIFGRAIASAKLA-
MUL_0721|M.ulcerans_Agy99 KGAELVFNGRVKSVDPDSK----SVTIALTATTGGKKIFGRAIASAKLA-
Mb0655|M.bovis_AF2122/97 KGAELVFNGRVKSVDPESK----SVTIALTATTGGKKIFGRAIASAKLA-
Rv0636|M.tuberculosis_H37Rv KGAELVFNGRVKSVDPESK----SVTIALTATTGGKKIFGRAIASAKLA-
MLBr_01909|M.leprae_Br4923 QGAVLVFSGKVKSVDPDTK----SVTIALSATTGGKKIFGRAIASAKLA-
Mflv_5120|M.gilvum_PYR-GCK KGAEIVFNGRVKSVDPESR----SVTIALSATSGGKKIFGRAVAIAKLA-
TH_1867|M.thermoresistible__bu KGAEIVFGGRVKSVDPETK----SVTIALTATAGGKKIFGRAIATAKLA-
MSMEG_6754|M.smegmatis_MC2_155 --TEIEYSGRIKSLDPETR----TGVVIVAAKSGGRKIFGLATATIRFS-
MAV_2649|M.avium_104 -GDVLTCSGTVTAVSAEPDAERVIVELTATRQTGGVAITGTAEFVNPRNA
MAB_2055|M.abscessus_ATCC_1997 -GDLLSFGGRVTGVREAGGQQVADLELVVTRQSGEPAIKGSAVVQVAR--
Mvan_3988|M.vanbaalenii_PYR-1 -HARPTCTGRVTDISVVDGERRATVEIVVTLADGTITLSGDAVVGL----
* :. : : : * : * *
MMAR_0969|M.marinum_M -----------
MUL_0721|M.ulcerans_Agy99 -----------
Mb0655|M.bovis_AF2122/97 -----------
Rv0636|M.tuberculosis_H37Rv -----------
MLBr_01909|M.leprae_Br4923 -----------
Mflv_5120|M.gilvum_PYR-GCK -----------
TH_1867|M.thermoresistible__bu -----------
MSMEG_6754|M.smegmatis_MC2_155 -----------
MAV_2649|M.avium_104 ARCGAGDADRP
MAB_2055|M.abscessus_ATCC_1997 -----------
Mvan_3988|M.vanbaalenii_PYR-1 -----------