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IEQTDLATIELQVADHVATVALNRPEKMNSFTEQMAAELAAVWARVRDDEDIRAAVLCANGERAFCTGID VTEGTWWKHRPIFNQEDPGELLGPKAHKVWKPVIAALHGIVAGGAMYFVNQCDFSICSETATFFDPHANA GIVSALEPMGMLALGVPYGEVMRWALLGSEERMSAQTALRIGLVTEVVPDDQLRVRAFELASEIAARRPN GVQGTVRAMWEARDLTPSVAARHGKFFTDLGNAGATPDSLNNKKKPRTR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2609 | - | - | 100% (260) | enoyl-CoA hydratase/isomerase family protein |
| M. avium 104 | MAV_1898 | - | e-134 | 88.63% (255) | enoyl-CoA hydratase/isomerase family protein |
| M. avium 104 | MAV_1581 | - | 3e-62 | 47.79% (249) | enoyl-CoA hydratase/isomerase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2855 | echA16 | 3e-19 | 32.16% (199) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4361 | - | 7e-63 | 50.00% (254) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv2831 | echA16 | 3e-19 | 32.16% (199) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_01241 | - | 4e-16 | 29.69% (229) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0836c | - | 1e-22 | 32.44% (225) | putative enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_4024 | echA16_1 | 2e-60 | 46.91% (243) | enoyl-CoA hydratase EchA16_1 |
| M. smegmatis MC2 155 | MSMEG_2218 | - | 2e-63 | 49.61% (258) | enoyl-CoA hydratase/isomerase family protein |
| M. thermoresistible (build 8) | TH_3648 | - | 3e-61 | 48.29% (234) | PUTATIVE Enoyl-CoA hydratase/isomerase |
| M. ulcerans Agy99 | MUL_3889 | echA16_1 | 9e-61 | 46.91% (243) | enoyl-CoA hydratase EchA16_1 |
| M. vanbaalenii PYR-1 | Mvan_1983 | - | 4e-60 | 47.60% (250) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4361|M.gilvum_PYR-GCK -------------MPMTFETIDLDLDHDVRVATITLNRPEALNSFNRAMC
Mvan_1983|M.vanbaalenii_PYR-1 ---------------MTFETILLDLDHEVRVATVTLNRPDALNSFNRAMC
MSMEG_2218|M.smegmatis_MC2_155 --------------MTEYETVLLDLDHEVRVATVTLNRPESLNSFNRTMC
MMAR_4024|M.marinum_M -------MTPQRSEKPDFTTILVDVNTTDHVATITLHRPDQLNAFNRTMC
MUL_3889|M.ulcerans_Agy99 -----MPVTPQRSEKPDFTTILVDVNTTDHVATITLHRPDQLNAFNRTMC
TH_3648|M.thermoresistible__bu ------------MSGPSFETIRLDVEPGDRVATITLNRPERLNAFNRTMC
MAV_2609|M.avium_104 -----------MIEQTDLATIELQVA--DHVATVALNRPEKMNSFTEQMA
Mb2855|M.bovis_AF2122/97 -----------------MTDDILLIDTDERVRTLTLNRPQSRNALSAALR
Rv2831|M.tuberculosis_H37Rv -----------------MTDDILLIDTDERVRTLTLNRPQSRNALSAALR
MAB_0836c|M.abscessus_ATCC_199 ----------------MSAARELLVERDGPVVILTMNRPHRRNALSTNMV
MLBr_01241|M.leprae_Br4923 MSQTDASCTIAELPYRSVTDLVVLDFPRPEVALITLNRPGRMNSMALDLM
: * ::::** *:: :
Mflv_4361|M.gilvum_PYR-GCK REMRDAWHLVKSDESINAVVLRAAGDRAFSAGLDVKS--------SYGQP
Mvan_1983|M.vanbaalenii_PYR-1 EEMKDVWRIIKADEGINAVVLRAAGERAFSAGLDVRA--------SYGQP
MSMEG_2218|M.smegmatis_MC2_155 EEMRQIWHVIKGDEQINAVVLRAAGDRAFSAGLDVKS--------RYGQP
MMAR_4024|M.marinum_M EEMAAAWHLIKHDESVHAVVLRAAGSRAFSAGLDIKT--------PYGQP
MUL_3889|M.ulcerans_Agy99 EEMAAAWHLIKHDESVHAVVLRAAGSRAFSAGLDIKT--------PYGQP
TH_3648|M.thermoresistible__bu EEMAQAWRAVKFDDRVHAVVLRAAGDRAFSAGLDIKS--------SYGQP
MAV_2609|M.avium_104 AELAAVWARVRDDEDIRAAVLCANGERAFCTGIDVTEG-------TWWKH
Mb2855|M.bovis_AF2122/97 DRFFAALADAEADDDIDVVILTGADP-VFCAGLDLKE-------LAGQTA
Rv2831|M.tuberculosis_H37Rv DRFFAALADAEADDDIDVVILTGADP-VFCAGLDLKE-------LAGQTA
MAB_0836c|M.abscessus_ATCC_199 SQFAAAWDEIDHDDGIRAAILTGAGS-AYCVGGDLSDGW-----MVRDGS
MLBr_01241|M.leprae_Br4923 KSLKQVLKRITYDHSVRVVVLTGAGR-GFCSGADQKFTAPVPQVEGLTQP
: *. : ..:* . . :. * *
Mflv_4361|M.gilvum_PYR-GCK DIVWNHEDPGELLSPKWQKMWKPVVCAVQGMCTAGALYFVNEADVVICSD
Mvan_1983|M.vanbaalenii_PYR-1 EIVWNHEDPGELLSPKWQKMWKPVVCAVQGMCTAGALYFVNEADIVICSR
MSMEG_2218|M.smegmatis_MC2_155 EIVWNHEDPGELLSPKWQKMWKPVVCAVHGMCTAGALYFVNESDVVICSS
MMAR_4024|M.marinum_M KNIWNHEDPGEFLSPKWRKMWKPVVCAVQGMCTAGAFYFINESDVVICST
MUL_3889|M.ulcerans_Agy99 KNIWNHEDPGEFLSPKWQKIWKPVVCAVQGMCTAGAFYFINESDVVICST
TH_3648|M.thermoresistible__bu DNVWNHEDPGELLSPKWQQMWKPVVCAVHGICTAGAFYFVNEADVVICSP
MAV_2609|M.avium_104 RPIFNQEDPGELLGPKAHKVWKPVIAALHGIVAGGAMYFVNQCDFSICSE
Mb2855|M.bovis_AF2122/97 LPDISPRWP---------AMTKPVIGAINGAAVTGGLELALYCDILIASE
Rv2831|M.tuberculosis_H37Rv LPDISPRWP---------AMTKPVIGAINGAAVTGGLELALYCDILIASE
MAB_0836c|M.abscessus_ATCC_199 APPLDPATIGKGL-LLSHTLTKPLIAAVNGACLGGGCEMLQQTDIRVSDE
MLBr_01241|M.leprae_Br4923 VRALRAMELLEEVILALRRLHQPVIAAINGPAIGGGLCLALAADVRVAST
: :*:: *::* *. : *. :..
Mflv_4361|M.gilvum_PYR-GCK GATFFDSHVSAGLVS-ALEPIGLMRR-VGLGDTLRMALMGNDERVGAQTA
Mvan_1983|M.vanbaalenii_PYR-1 GATFFDSHVSAGLVC-ALEPVGLMRR-IGLGDTLRMALMGNDERVGAETA
MSMEG_2218|M.smegmatis_MC2_155 DATFFDSHVSAGLVS-ALEPVGLMRR-VGLGDTLRMALMGNDERVSADTA
MMAR_4024|M.marinum_M GATFFDSHVSAGLVC-ALEPIGLMRR-IGLGETLRIALMGNDERVGAETA
MUL_3889|M.ulcerans_Agy99 GATFFDSHVSAGLVC-ALEPIGLMRR-IGLGETLRIALMGNDERVGAETA
TH_3648|M.thermoresistible__bu DATFFDSHVSAGLVC-ALEPIGLMRK-VGLAETLRIALMGNDERIGAETA
MAV_2609|M.avium_104 TATFFDPHANAGIVS-ALEPMGMLALGVPYGEVMRWALLGSEERMSAQTA
Mb2855|M.bovis_AF2122/97 HARFADTHARVGLLP-TWGLSVRLPQKVGIGLARRMSLTG--DYLSATDA
Rv2831|M.tuberculosis_H37Rv HARFADTHARVGLLP-TWGLSVRLPQKVGIGLARRMSLTG--DYLSATDA
MAB_0836c|M.abscessus_ATCC_199 HATFGLPEVQRGLVP-GAGSMVRLKRQIPYTKAMEMILTG--EPLTAFEA
MLBr_01241|M.leprae_Br4923 RAYFRAAGINNGLSASELGLSYLLPRAVGSSRAFEIMLSG--RDVGAEEA
* * . *: : : . . * * : * *
Mflv_4361|M.gilvum_PYR-GCK LRIGLVTEVVPEDELWSRAHEIATAIAAKPPTATQGTVKAIWESLDKPYR
Mvan_1983|M.vanbaalenii_PYR-1 LRIGLVTEVVDENDLWARAHEIATTIAAKPPTATQGTVKAIWESLDKPYR
MSMEG_2218|M.smegmatis_MC2_155 LRIGLVTEVVPREQLWARAHQIASTIATKPPTATQGTVRAIWESLDRPYR
MMAR_4024|M.marinum_M LRIGLVSEVVAPQRLWERAHEIAATIAAKPPSATQGTVKAIWESLDKPYR
MUL_3889|M.ulcerans_Agy99 LRIGLVSEVVAPQRLWGRAHEIAATIAAKPPSATQGTVKAIWESLDKPYR
TH_3648|M.thermoresistible__bu LRISLVTEIVPREQLWDRAHEIAATIAAKPPSATQGTVKAIWESLDRPYR
MAV_2609|M.avium_104 LRIGLVTEVVPDDQLRVRAFELASEIAARRPNGVQGTVRAMWEARDLTPS
Mb2855|M.bovis_AF2122/97 LRAGLVTEVVAHDQLLPTARRVAASIVGNNQNAVRALLASYHRIDESQTA
Rv2831|M.tuberculosis_H37Rv LRAGLVTEVVAHDQLLPTARRVAASIVGNNQNAVRALLASYHRIDESQTA
MAB_0836c|M.abscessus_ATCC_199 YHFGLVGHVVPAGTALDKARSLADRIVRNGPLAVRNAKEAIVRSGWLAEE
MLBr_01241|M.leprae_Br4923 EQIGLVSYRVSDDRLLDTCYSIAARMATFSRSGTELTKRALWGGLDAASL
: .** * . :* :. ... :
Mflv_4361|M.gilvum_PYR-GCK AAMDQGLIYTRLGNPIAKAELAERPI--PKTAPRIR-----------
Mvan_1983|M.vanbaalenii_PYR-1 AAMDQGLIYTRLGNPIAKAELAERPV--PKTPPRIR-----------
MSMEG_2218|M.smegmatis_MC2_155 AAMDQGLIYTRLGNPIAKAELADRPV--PKTPPRIR-----------
MMAR_4024|M.marinum_M AAVEQGLIYTRLGNPLGRAELADLPPRPDGSEPKTR-----------
MUL_3889|M.ulcerans_Agy99 AAVEQGLIYTRLGNPLGRAELADLPPRPDGSEPKTR-----------
TH_3648|M.thermoresistible__bu AAMEQGLIYTRLGNPLGQAELAEAAP-THVPAPRIR-----------
MAV_2609|M.avium_104 VAARHGKFFTDLGNAGATPDSLNNKK-----KPRTR-----------
Mb2855|M.bovis_AF2122/97 AGLWLEACAAKQFCTSGDTIAANREAVLQRGRAQVR-----------
Rv2831|M.tuberculosis_H37Rv AGLWLEACAAKQFRTSGDTIAANREAVLQRGRAQVR-----------
MAB_0836c|M.abscessus_ATCC_199 DARAIEARLTRPVITSADAREG-LAAFKEKREARFTGR---------
MLBr_01241|M.leprae_Br4923 DKHMQSESLAQLFIALHTSNFEEAAAPCTEKRPTVLVDARGCATSPG
: . . .