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GRSLHAIHASQPTLNAFRVVLTESALADAAEADRRRAAGDTAPLLGIPIAVKDDVDIAGVPTAFGTEGSV PPATHDAEVVRRLKAAGAVIVGKTNTCELGQWPFTSGPGFGHTRNPWSRRHTPGGSSGGSAAAVAAGLVT AAIGSDGAGSIRIPAAWTHLVGIKPQRGRISTWPLPEAFNGITVNGVLARTVADAALVLDAASGNVDGDR HKPPPITASDYVGKAPGPLNIALSTRFPYTGFRPKLHPEILAATRAVGKQLELLGHTVVPGNPDYGMRLS WDFLARSTAGLRDWEERLGDGVVLDPRTVANLRLGHLLGQAILRSARRHEAADQRRVGSIFDIVDVVLAP TTAQPPPLARAFDRLSGFGTDRAMIAACPLTFPWNVLGWPSINVPAGFTSDGLPIGVQLMGPANSEGMLI SLAAELEAVSGWASKQPQPWWDQSADTPPAPGQPAPTG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2032 | - | - | 100% (459) | amidase |
| M. avium 104 | MAV_1414 | - | 9e-89 | 44.86% (428) | amidase |
| M. avium 104 | MAV_0676 | - | 1e-52 | 35.27% (465) | 6-aminohexanoate-cyclic-dimer hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2384 | amiA2 | 0.0 | 89.14% (442) | amidase |
| M. gilvum PYR-GCK | Mflv_2712 | - | 0.0 | 73.95% (453) | amidase |
| M. tuberculosis H37Rv | Rv2363 | amiA2 | 0.0 | 89.14% (442) | amidase |
| M. leprae Br4923 | MLBr_01596 | - | 5e-46 | 34.92% (421) | amidase |
| M. abscessus ATCC 19977 | MAB_1674c | - | 1e-174 | 68.34% (439) | amidase |
| M. marinum M | MMAR_3673 | amiA2 | 0.0 | 85.71% (448) | amidase AmiA2 |
| M. smegmatis MC2 155 | MSMEG_4492 | - | 0.0 | 74.45% (458) | amidase |
| M. thermoresistible (build 8) | TH_4482 | - | 0.0 | 76.50% (451) | PUTATIVE Amidase |
| M. ulcerans Agy99 | MUL_3616 | amiA2 | 0.0 | 85.04% (448) | amidase |
| M. vanbaalenii PYR-1 | Mvan_3824 | - | 0.0 | 73.36% (458) | amidase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2384|M.bovis_AF2122/97 MVGASGSDAGAISGSGNQRLPTLTDLLYQLATRAVTSEELVRRSLRAIDV
Rv2363|M.tuberculosis_H37Rv MVGASGSDAGAISGSGNQRLPTLTDLLYQLATRAVTSEELVRRSLRAIDV
MMAR_3673|M.marinum_M MVGASGFASGAVSGSGGPRLPTLTDLLYQLASGSVTSVELTRRSLREIEV
MUL_3616|M.ulcerans_Agy99 MVGASGFASGAVSGSGGPRLPTLTDLLYQLASGSVTSVELTRRSLREIEV
MAV_2032|M.avium_104 ----------------------------------------MGRSLHAIHA
Mflv_2712|M.gilvum_PYR-GCK -MPDSS-ARSTSRNRFPDRFPTVANQLFQLASGTATSVDLVRRSLVAIEA
Mvan_3824|M.vanbaalenii_PYR-1 -MADTAYSRITSRR----RFPTLGNQLFQLASGTATSVDLVSRSLQAIEA
TH_4482|M.thermoresistible__bu -MVDAYKPPAK--------LPTLTDLLYQLASGAVTSQELVRRSLRAIEA
MSMEG_4492|M.smegmatis_MC2_155 MMGKSTACEST--------FPTLTNQLYQLASGAVTSDELVRRSLHAINA
MAB_1674c|M.abscessus_ATCC_199 -MSG---------------FPTLTSQAAALSDGSESSVSLTLTALNAIKS
MLBr_01596|M.leprae_Br4923 -MQRVHAFGDDALG-----DLDAVGLADAIRAGWVSRADVIEAAIVRTEA
:: .
Mb2384|M.bovis_AF2122/97 SQPTLNAFRVVLTESALADAAAADKRRAAG---DTAPLLGIPIAVKDDVD
Rv2363|M.tuberculosis_H37Rv SQPTLNAFRVVLTESALADAAAADKRRAAG---DTAPLLGIPIAVKDDVD
MMAR_3673|M.marinum_M SQSTLNAFRVVLTESALADAAAADRRRAAG---DAAPLLGIPIAVKDDVD
MUL_3616|M.ulcerans_Agy99 SQSTLNAFRVVLTESALADAAAADRRRAAG---DAAPLLGIPIAVKDDVD
MAV_2032|M.avium_104 SQPTLNAFRVVLTESALADAAEADRRRAAG---DTAPLLGIPIAVKDDVD
Mflv_2712|M.gilvum_PYR-GCK SQPTLNAFRVVLAERALADAAEADRLRAAGHDRARRPLLGIPIAVKDDVD
Mvan_3824|M.vanbaalenii_PYR-1 SQPTLNAFRVVLTEQALADAAEADRKRAAGADLSRHPLLGVPIAVKDDVD
TH_4482|M.thermoresistible__bu SQSTLNAFRVVLADRALAEAAEADRKRAAG---EHLPLLGVPIAVKDDVD
MSMEG_4492|M.smegmatis_MC2_155 SQSTLNAFRVVLTEQALADAAKADRDRAAG---KQLPLLGVPIAVKDDVD
MAB_1674c|M.abscessus_ATCC_199 SQSTLNAFRVVCTKTALAEATEADKRLARG---ERLPLLGVPIAIKDDTD
MLBr_01596|M.leprae_Br4923 VNPALGGLAYEAFQWARQTASKAGSGFFSG----------VPTFIKDNID
:.:*..: . * *: *. * :* :**: *
Mb2384|M.bovis_AF2122/97 VAGVPTAFGTQGYVAP-ATDDCEVVRRLKAAGAVIVGKTNTCELGQWPFT
Rv2363|M.tuberculosis_H37Rv VAGVPTAFGTQGYVAP-ATDDCEVVRRLKAAGAVIVGKTNTCELGQWPFT
MMAR_3673|M.marinum_M VAGVPTAFGTQGYVRP-AAHDSEVVRRLKAAGAVIIGKTNTCELGQWPFT
MUL_3616|M.ulcerans_Agy99 VAGVPTAFGTQGYVQP-AAHDSEVVRRLKAAGAVIIGKTNTCELGQWPFT
MAV_2032|M.avium_104 IAGVPTAFGTEGSVPP-ATHDAEVVRRLKAAGAVIVGKTNTCELGQWPFT
Mflv_2712|M.gilvum_PYR-GCK VAGVPTRFGASGEVPE-AVADAEVVRRLRAAGAVIVGKTNTCELGQWPFT
Mvan_3824|M.vanbaalenii_PYR-1 VAGVPTRFGADGEVPP-AEADAEVVRRLRAAGAVIVGKTNTCELGQWPFT
TH_4482|M.thermoresistible__bu IAGVPTRFGAVGDVPP-ATEDAEVVRRLRAAGAVIVGKTHTCELGQWPFT
MSMEG_4492|M.smegmatis_MC2_155 IAGVPTRFGTEGDGRV-AEADSEVARRLRAAGAVIVGKTNTCELGQWHFT
MAB_1674c|M.abscessus_ATCC_199 LAGTPTAFGTAGAVGS-ESEDAELVRRLRAAGAVIVGKTNTCELGQWGFT
MLBr_01596|M.leprae_Br4923 VAGQPTMRGSDAWVPRNAFDDGEFTRLYLATGPVSLGKTQLSEFGFSASA
:** ** *: . * *..* *:*.* :***: .*:* :
Mb2384|M.bovis_AF2122/97 SGPGFGHTRNPWSRRHTPGGSSGGSAAAVAAGLVTAAIGSDGAGSIRIPA
Rv2363|M.tuberculosis_H37Rv SGPGFGHTRNPWSRRHTPGGSSGGSAAAVAAGLVTAAIGSDGAGSIRIPA
MMAR_3673|M.marinum_M SGPGFGHTRNPWARRHTPGGSSGGSAAAVAAGLVTAAIGSDGAGSIRVPA
MUL_3616|M.ulcerans_Agy99 SGPGFGHTRNPWARRHTPGGSSGGSAAAVAAGLVTAAIGSDGAGSIRVPA
MAV_2032|M.avium_104 SGPGFGHTRNPWSRRHTPGGSSGGSAAAVAAGLVTAAIGSDGAGSIRIPA
Mflv_2712|M.gilvum_PYR-GCK SGPAFGHTRNPWSREHTPGGSSGGSAAAVAAGLVAAAIGSDGAGSVRIPA
Mvan_3824|M.vanbaalenii_PYR-1 SGPAFGHTRNPWSREHTPGGSSGGSAAAVAAGLVAAAIGSDGAGSVRIPA
TH_4482|M.thermoresistible__bu SGPAFGHTRNPWSPRHTPGGSSGGSAAAVAAGLVTAAIGSDGAGSVRIPA
MSMEG_4492|M.smegmatis_MC2_155 SGPGFGHTRNPWSRKHTPGGSSGGSAAAVAAGLVTAAIGSDGAGSVRIPA
MAB_1674c|M.abscessus_ATCC_199 SGPGFGHTRNPWSRGHTPGGSSGGSAAAVAAGLVAGAIGSDGAGSVRIPA
MLBr_01596|M.leprae_Br4923 EHMRLGPVRNPWDTDYTAGASSSGSGAFVAAGVVPMAHANDGGGSIRIPA
. :* .**** :*.*.**.**.* ****:*. * ..**.**:*:**
Mb2384|M.bovis_AF2122/97 AWTHLVGIKPQRGRIST-WPLPEAFNGVTVNGVLARTVEDAALVLDAASG
Rv2363|M.tuberculosis_H37Rv AWTHLVGIKPQRGRIST-WPLPEAFNGVTVNGVLARTVEDAALVLDAASG
MMAR_3673|M.marinum_M AWTHLVGIKPQRGRIST-WPWPETFNGITVNGVLARTVADAALVLDAASG
MUL_3616|M.ulcerans_Agy99 AWTHLVGIKPQRGRIST-WPWPETFNGITVNGVLARTVADAALVLDAASG
MAV_2032|M.avium_104 AWTHLVGIKPQRGRIST-WPLPEAFNGITVNGVLARTVADAALVLDAASG
Mflv_2712|M.gilvum_PYR-GCK AWTHLVGIKPQRGRIST-SPLPEAFNGITVNGVLARTVSDAAMVLDAAAG
Mvan_3824|M.vanbaalenii_PYR-1 AWTHLVGIKPQRGRIST-WPLTEAFNGITVHGVLARTVSDAALLLDAASG
TH_4482|M.thermoresistible__bu AWTHLVGIKPQRGRIST-WPLPEAFNGITVHGVLARTVTDAALVLDAASG
MSMEG_4492|M.smegmatis_MC2_155 AWTHLVGIKPQRGRIST-WPQPEAFNGVTVHGVLARTVVDAALVLDAASG
MAB_1674c|M.abscessus_ATCC_199 AWTHLIGIKPQRGRIST-WPFAEAFNGITVHGPLARTVADAALLLDAASG
MLBr_01596|M.leprae_Br4923 SCNGLVGLKPSRGRLPLDSELRRLPVGIVVNGVLTRSVRDTAAFYREAER
: . *:*:**.***:. . *:.*:* *:*:* *:* . *
Mb2384|M.bovis_AF2122/97 NVEGDRHQPPPVTVSDFVGIAPGPLKIALSTHFPYTGFRAKLHPEILAAT
Rv2363|M.tuberculosis_H37Rv NVEGDRHQPPPVTVSDFVGIAPGPLKIALSTHFPYTGFRAKLHPEILAAT
MMAR_3673|M.marinum_M NVEGDLHKPAPLTASDYVGIAPGPLKIAMSTRFPYTGFRAKLHPEILAAT
MUL_3616|M.ulcerans_Agy99 NAEGDLHKPAPLTASDYVGIAPGPLKIAMSTRFPYTGFRAKLHPEILAST
MAV_2032|M.avium_104 NVDGDRHKPPPITASDYVGKAPGPLNIALSTRFPYTGFRPKLHPEILAAT
Mflv_2712|M.gilvum_PYR-GCK NAAGDLHTPAPVTVSDFVSRAPGPLRVAVSTRFPFTGFRATLHPEIRSAL
Mvan_3824|M.vanbaalenii_PYR-1 NAPGELHTPPPVRVSDYVSRAPGPLRIAMSTKFPFTVFRAGLHPEIRTAL
TH_4482|M.thermoresistible__bu NAPGDLHQPPPVRVSDYVGQAPGPLRIAVSTKFPFTLFRAKLHPEIRAAV
MSMEG_4492|M.smegmatis_MC2_155 NADGDLHKPAPIQASDYVGVAPGPLRIAMSTKIPFTGVRAKIHPEILAAL
MAB_1674c|M.abscessus_ATCC_199 NVPGDLHKPPHVRVLDAVHEDPGQLRVALSLKVPFSGFPAQLHPTIEAAT
MLBr_01596|M.leprae_Br4923 ----IWHNPKLPPVGDVTQPGRQRLRIAVVTRS----VQRECSPELRELT
* * . * . *.:*: : . * :
Mb2384|M.bovis_AF2122/97 QRVGDQLELLGHTVV-KGNPDYGLRLSWNFLARS--TAGLWEWAERL---
Rv2363|M.tuberculosis_H37Rv QRVGDQLELLGHTVV-KGNPDYGLRLSWNFLARS--TAGLWEWAERL---
MMAR_3673|M.marinum_M RRVGEQLQLLGHTVE-RGNPDYGLRLSWDFLARS--TAGLWEWAECL---
MUL_3616|M.ulcerans_Agy99 RRVGEQLQLLGHTVE-RGNPDYGLRLSWDFLARS--TAGLWEWAECL---
MAV_2032|M.avium_104 RAVGKQLELLGHTVV-PGNPDYGMRLSWDFLARS--TAGLRDWEERL---
Mflv_2712|M.gilvum_PYR-GCK DGVADQLSQLGHTVL-NADPDYTLGMSWNFLARS--TSGIPEWMDRL---
Mvan_3824|M.vanbaalenii_PYR-1 QNVADQLTQLGHTIV-AADPDYHLRMSWNFLSRS--TSGIPEWMDRL---
TH_4482|M.thermoresistible__bu QTVADQLEQLGHTVF-PADPEYTVGMSWSFLSRS--TAGLLDWSRRL---
MSMEG_4492|M.smegmatis_MC2_155 QTIADHLGELGHTVK-AKDPNYSLRMSWDFLSRS--TAGLLDWDDRLDTA
MAB_1674c|M.abscessus_ATCC_199 RYVAHQLRSLGHMVS-EGDPDYGVGLGLNFLPRA--TAGLLPWRDRL---
MLBr_01596|M.leprae_Br4923 LKSARLLEELGHRVERVAEPPVPPNFPDDFLLYWGLLAAMQVRTGRL---
. * *** : :* : .** :.: *
Mb2384|M.bovis_AF2122/97 GDEVTLDRRTVSNLRMG----HVLSQAILRSARRHEAADQRRVGSIFDIV
Rv2363|M.tuberculosis_H37Rv GDEVTLDRRTVSNLRMG----HVLSQAILRSARRHEAADQRRVGSIFDIV
MMAR_3673|M.marinum_M GDGVTLDPRTVTNMRAG----HALSQAILRNARHHEAAAQRRVGSIFDIV
MUL_3616|M.ulcerans_Agy99 GNGVTLDPRTVTNMRAG----HALSQAILRNARHHEAAAQRRVGSIFDIV
MAV_2032|M.avium_104 GDGVVLDPRTVANLRLG----HLLGQAILRSARRHEAADQRRVGSIFDIV
Mflv_2712|M.gilvum_PYR-GCK GHRVTWDSRTRSNARMG----RLLSQHTLRKARAREAAAQQRIGWIFNLA
Mvan_3824|M.vanbaalenii_PYR-1 GRGVNWDSRTRSNARMG----WLLSQNVLRKARAGEAASQQRIGWIFNLA
TH_4482|M.thermoresistible__bu GDNVLWDKRTVANMRLG----RLLSESALRKARAREAAAQRRMSWIFNIA
MSMEG_4492|M.smegmatis_MC2_155 GHGVVYDHRTVANMRIG----RLLSQNVLRKARAHEAAVQRRMSWIFNLV
MAB_1674c|M.abscessus_ATCC_199 DAGAHWDPRTVTNMRTG----RRLAGWALRRARAAEPRLQARVGKIFGSF
MLBr_01596|M.leprae_Br4923 AFGNTFDRTKLDSLTLGLDRHASRNMHRLPKAIMRLRRLRRRTADFFATY
* . . * * * : * . :*
Mb2384|M.bovis_AF2122/97 DVVLAPTTAQPPPMARAFDRLGSFGTDRAIIAACPSTWPWNLLGWPSINV
Rv2363|M.tuberculosis_H37Rv DVVLAPTTAQPPPMARAFDRLGSFGTDRAIIAACPSTWPWNLLGWPSINV
MMAR_3673|M.marinum_M DVVLAPTTAQPPPLARAFDDMGGLATDRAIIAACPLTWPWNLLGWPSINV
MUL_3616|M.ulcerans_Agy99 DVVLAPTTAQPPPLARAFDDMGGLATDRAIIAACPLTWPWNLLGWPSINV
MAV_2032|M.avium_104 DVVLAPTTAQPPPLARAFDRLSGFGTDRAMIAACPLTFPWNVLGWPSINV
Mflv_2712|M.gilvum_PYR-GCK DVVVAPTTAQPPPEAHAFDGLGGLATDRMMIRACPVTWPWNLLGWPSINV
Mvan_3824|M.vanbaalenii_PYR-1 DVVLAPTTALPPPEVRAFDDLGGLATDRMMIKACPVTWPWNLLGWPSINV
TH_4482|M.thermoresistible__bu DVVLAPTTALPPPEVHAFDQLGGLATDRLMIKACPVTWPWNLLGWPSINV
MSMEG_4492|M.smegmatis_MC2_155 DVIIAPTTAQPPPPVHECDRLGWLATERKAIAACPLTWAWNLLGWPSINV
MAB_1674c|M.abscessus_ATCC_199 NVVLAPTTAQPPTGIYDFDDVGSLATDRGQVGACPMTWPWNVLGWPSINV
MLBr_01596|M.leprae_Br4923 DVLLTPTVADETPRIGYLTPTDYQQVMDRLMGWVAFTPLQNVTGEPAISL
:*:::**.* .. . . : . * *: * *:*.:
Mb2384|M.bovis_AF2122/97 PAGFTSDGLPIGVQLMGPANSEGMLISLAAELEAVSGWATKQPQVWWTS-
Rv2363|M.tuberculosis_H37Rv PAGFTSDGLPIGVQLMGPANSEGMLISLAAELEAVSGWATKQPQVWWTS-
MMAR_3673|M.marinum_M PAGFTVDGLPIGVQLMGPAESEGLLISLAAELEAVSGWATKQPKVWWNTG
MUL_3616|M.ulcerans_Agy99 PAGFTVDGLPIGVQLMGPAESEGLLISLAAELEAVSGWATKQPKVWWNTG
MAV_2032|M.avium_104 PAGFTSDGLPIGVQLMGPANSEGMLISLAAELEAVSGWASKQPQPWWDQS
Mflv_2712|M.gilvum_PYR-GCK PAGFTSDGLPIGVQLMGPADSEPLLISLAAALEAINGWATLQPENWWAPQ
Mvan_3824|M.vanbaalenii_PYR-1 PAGFTSDGLPIGVQLMGPANSEPLLVSLAAALEAINGWAVHQPEDWWTPQ
TH_4482|M.thermoresistible__bu PAGFTSDGLPIGVQLMGPANSEPLLVSLAAALEGINGWAARQPRPWWLT-
MSMEG_4492|M.smegmatis_MC2_155 PAGFTSDGLPIGVQLMGPAESEPLLISLAAELEAITGWAAREPEVWWNTP
MAB_1674c|M.abscessus_ATCC_199 PAGFTADGLPIGVQLMGPANSEPLLISLAAQLESINNWASEIPDPWW---
MLBr_01596|M.leprae_Br4923 PLAQSADGMPVGMMFTADFGQEAQLLELAFELEEARPWARIQIGD-----
* . : **:*:*: : . .* *:.** ** **
Mb2384|M.bovis_AF2122/97 -------------------------------------------------
Rv2363|M.tuberculosis_H37Rv -------------------------------------------------
MMAR_3673|M.marinum_M --TSTPPIHSV----RPPRR-----------------------------
MUL_3616|M.ulcerans_Agy99 --TSTPPIHSV----RPPRR-----------------------------
MAV_2032|M.avium_104 --ADTPPAPGQ----PAPTG-----------------------------
Mflv_2712|M.gilvum_PYR-GCK ----PPTEPDL----TAPDSVTGQVA-----------------------
Mvan_3824|M.vanbaalenii_PYR-1 ----PPPEPDLGSNVAAPASVEGQVA-----------------------
TH_4482|M.thermoresistible__bu ----PPAAPXX----XASAAAS---------------------------
MSMEG_4492|M.smegmatis_MC2_155 EGRGLPPVSEITQRVPAPEDEKPAVETTDKPSEPVDDVSQAVAAVNALR
MAB_1674c|M.abscessus_ATCC_199 -------------------------------------------------
MLBr_01596|M.leprae_Br4923 -------------------------------------------------