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SRLPGVSDRDAGLGARIAFFFTRRKLAQMTGLETAGMLEPLRMYAHIPRLLNAHGRLEQAESRLDILSPR HRALAELKAATTVRCEYCIDLGSQIARRWGITDEELLAMADYRDAACFSDVDKLILEYATAISRTPVEVS DELFDALRAHFDTAQLVGLTHVITLGNLRARFNIALGIGSSGFSGNRVCALPDTPRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2020 | pcaC | - | 100% (198) | hypothetical protein MAV_2020 |
| M. avium 104 | MAV_4302 | - | 3e-21 | 32.64% (193) | transposase |
| M. avium 104 | MAV_0906 | pcaC | 2e-06 | 31.29% (147) | hypothetical protein MAV_0906 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3360 | - | 2e-21 | 33.17% (202) | transposase |
| M. gilvum PYR-GCK | Mflv_4851 | - | 9e-22 | 31.82% (198) | hypothetical protein Mflv_4851 |
| M. tuberculosis H37Rv | Rv3327 | - | 2e-21 | 33.17% (202) | transposase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3677 | - | 2e-21 | 30.81% (198) | transposase fusion protein |
| M. marinum M | MMAR_3686 | - | 3e-88 | 80.30% (198) | hypothetical protein MMAR_3686 |
| M. smegmatis MC2 155 | MSMEG_6370 | pcaC | 2e-06 | 28.97% (107) | 4-carboxymuconolactone decarboxylase |
| M. thermoresistible (build 8) | TH_2184 | - | 1e-20 | 32.14% (196) | PROBABLE TRANSPOSASE FUSION PROTEIN |
| M. ulcerans Agy99 | MUL_3629 | - | 4e-86 | 79.79% (193) | hypothetical protein MUL_3629 |
| M. vanbaalenii PYR-1 | Mvan_1576 | - | 2e-19 | 30.61% (196) | hypothetical protein Mvan_1576 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3686|M.marinum_M --------------------------------------------------
MUL_3629|M.ulcerans_Agy99 --------------------------------------------------
MAV_2020|M.avium_104 --------------------------------------------------
Mb3360|M.bovis_AF2122/97 MVVVGTDAHKYSHTFVATDEVGRQLGEKTVKATTAGHATAIMWAREQFGL
Rv3327|M.tuberculosis_H37Rv MVVVGTDAHKYSHTFVATDEVGRQLGEKTVKATTAGHATAIMWAREQFGL
MAB_3677|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_4851|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1576|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2184|M.thermoresistible__bu --------------------------------------------------
MSMEG_6370|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3686|M.marinum_M --------------------------------------------------
MUL_3629|M.ulcerans_Agy99 --------------------------------------------------
MAV_2020|M.avium_104 --------------------------------------------------
Mb3360|M.bovis_AF2122/97 ELIWGIEDCRNMSARLERDLLAAGQQVVRVPTKLMAQTRKSARSRGKSDP
Rv3327|M.tuberculosis_H37Rv ELIWGIEDCRNMSARLERDLLAAGQQVVRVPTKLMAQTRKSARSRGKSDP
MAB_3677|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_4851|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1576|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2184|M.thermoresistible__bu --------------------------------------------------
MSMEG_6370|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3686|M.marinum_M --------------------------------------------------
MUL_3629|M.ulcerans_Agy99 --------------------------------------------------
MAV_2020|M.avium_104 --------------------------------------------------
Mb3360|M.bovis_AF2122/97 IDALAVARAVLRETDLPLATHDETSRELKLLTDRRDVLVAQRTSAINRLR
Rv3327|M.tuberculosis_H37Rv IDALAVARAVLRETDLPLATHDETSRELKLLTDRRDVLVAQRTSAINRLR
MAB_3677|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_4851|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1576|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2184|M.thermoresistible__bu --------------------------------------------------
MSMEG_6370|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3686|M.marinum_M --------------------------------------------------
MUL_3629|M.ulcerans_Agy99 --------------------------------------------------
MAV_2020|M.avium_104 --------------------------------------------------
Mb3360|M.bovis_AF2122/97 WLVHELDPERAPAARSLDAAKHQQALRTWLDTQPGLVAELARAELTDIIR
Rv3327|M.tuberculosis_H37Rv WLVHELDPERAPAARSLDAAKHQQALRTWLDTQPGLVAELARAELTDIIR
MAB_3677|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_4851|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1576|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2184|M.thermoresistible__bu --------------------------------------------------
MSMEG_6370|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3686|M.marinum_M --------------------------------------------------
MUL_3629|M.ulcerans_Agy99 --------------------------------------------------
MAV_2020|M.avium_104 --------------------------------------------------
Mb3360|M.bovis_AF2122/97 LTGEINTLAQRISARVHQVAPALLEIPGCAELTAAKIVGEAAGVTRFKSE
Rv3327|M.tuberculosis_H37Rv LTGEINTLAQRISARVHQVAPALLEIPGCAELTAAKIVGEAAGVTRFKSE
MAB_3677|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_4851|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1576|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2184|M.thermoresistible__bu --------------------------------------------------
MSMEG_6370|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3686|M.marinum_M --------------------------------------------------
MUL_3629|M.ulcerans_Agy99 --------------------------------------------------
MAV_2020|M.avium_104 --------------------------------------------------
Mb3360|M.bovis_AF2122/97 AAFACHAAVAPIPVWSGNTAGQMRLSRSGNRQLNAALHRIALTQIRMTDS
Rv3327|M.tuberculosis_H37Rv AAFACHAAVAPIPVWSGNTAGQMRLSRSGNRQLNAALHRIALTQIRMTDS
MAB_3677|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_4851|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1576|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2184|M.thermoresistible__bu --------------------------------------------------
MSMEG_6370|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3686|M.marinum_M --------------------------------------------------
MUL_3629|M.ulcerans_Agy99 --------------------------------------------------
MAV_2020|M.avium_104 --------------------------------------------------
Mb3360|M.bovis_AF2122/97 RGQAYYQRLQDAGKTKRAALRCLKRRLARTVFQALRTVHQPSSEHTQPAA
Rv3327|M.tuberculosis_H37Rv RGQAYYQRLQDAGKTKRAALRCLKRRLARTVFQALRTVHQPSSEHTQPAA
MAB_3677|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_4851|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1576|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2184|M.thermoresistible__bu --------------------------------------------------
MSMEG_6370|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3686|M.marinum_M ----------------------MSRLVGVSDHDAGIAAKIAFFFTKRKLA
MUL_3629|M.ulcerans_Agy99 --------------------------MGVSDHDAGIAAKIAFFFTKRKLA
MAV_2020|M.avium_104 ----------------------MSRLPGVSDRDAGLGARIAFFFTRRKLA
Mb3360|M.bovis_AF2122/97 ACHRSYCSSHLGEPPRLTDMTQKTRIQPLPPKRAGLLIRALYRIAKRRFG
Rv3327|M.tuberculosis_H37Rv ACHRSYCSSHLGEPPRLTDMTQKTRIQPLPPKRAGLLIRALYRIAKRRFG
MAB_3677|M.abscessus_ATCC_1997 -------------------MTTTSRIAPIAPPNASLLTRFMYRVTKRRYG
Mflv_4851|M.gilvum_PYR-GCK -------------------MTTTTRIEPVSPQRASLMTRLLWRYAKRRFG
Mvan_1576|M.vanbaalenii_PYR-1 ---------------------MTTRLEPVPPHRASLLTRLMWRYAKRRFG
TH_2184|M.thermoresistible__bu -----------------MSENQKTRIEPLSPERAPWWVRLMYRYARRRFG
MSMEG_6370|M.smegmatis_MC2_155 -------------------------------------MTQTLESTER---
:.*
MMAR_3686|M.marinum_M RMAGLATADMLEPLRMYAHIPRLLNAYGRLEQAESKLD-VLTARHRALAE
MUL_3629|M.ulcerans_Agy99 RMAGLATADMLEPLRIYAHIPRLLNAYGRLEQAESKLD-VLTARHRALAE
MAV_2020|M.avium_104 QMTGLETAGMLEPLRMYAHIPRLLNAHGRLEQAESRLD-ILSPRHRALAE
Mb3360|M.bovis_AF2122/97 EVP--------EPFTVTAHHRRLLIANVVHEALLQRASRKLPPSVRELAV
Rv3327|M.tuberculosis_H37Rv EVP--------EPFTVTAHHRRLLIANVVHEALLQRASRKLPPSVRELAV
MAB_3677|M.abscessus_ATCC_1997 QVP--------EPFTVIAHHRKLMVAAAVHEQMLGSASQVLPTSVRELAV
Mflv_4851|M.gilvum_PYR-GCK EVP--------EPFTIYAHHPGVMLAGAMHEGMLERASTALPANVRELAV
Mvan_1576|M.vanbaalenii_PYR-1 EVP--------EPFAVYAHHPGLMLTGAVHEGLLERTSSKVPASVRELAV
TH_2184|M.thermoresistible__bu EVP--------EPFTVAAHHPGLLLSSAVHETLLEKTSSRLPANVRELAV
MSMEG_6370|M.smegmatis_MC2_155 -------------VKIYKAFPEFYDA---MMNLSATSAKDFDHTIGELVK
. : . : . *.
MMAR_3686|M.marinum_M LKAATTVGCQYCIDLGSQIARELGISDQELLALANYRDA-SCFSEVDRLI
MUL_3629|M.ulcerans_Agy99 LKAATTVGCQYCIDLGSQIARELGISDQELLALANYRDA-SCFSEVDRLI
MAV_2020|M.avium_104 LKAATTVRCEYCIDLGSQIARRWGITDEELLAMADYRDA-ACFSDVDKLI
Mb3360|M.bovis_AF2122/97 FWTARSIGCSWCVDFGAMLQRLDGLDVDRLTDIDNYATS-SKFSDDERAA
Rv3327|M.tuberculosis_H37Rv FWTARSIGCSWCVDFGAMLQRLDGLDVDRLTDIDNYATS-SKFSDDERAA
MAB_3677|M.abscessus_ATCC_1997 FWTARTVGCSWCVDFGSMLQRLDGLDVDRLKAIDDYATS-PLYTEDERVA
Mflv_4851|M.gilvum_PYR-GCK YWVARQIGCSWCVDFGAMLMRLDGLDLARLTHIDDYATS-TSFTDDERAA
Mvan_1576|M.vanbaalenii_PYR-1 YWTARQIGCSWCVDFGSMLMRLDGLDIARLKEIDDFATS-PRFTDDERAA
TH_2184|M.thermoresistible__bu YWTARKIGCSWCVDFGAMLARLDGLNIEKLSRIDDYATS-DLFDDDERAA
MSMEG_6370|M.smegmatis_MC2_155 IRASQINRCGFCLDMHARDARKQGETEQRLALIAAWEEAGDLFTEREQAA
.: * :*:*: : * * .* : : : : : ::
MMAR_3686|M.marinum_M LDYAAAISRTP-VAVSDELFAALRAHFDAAALVGLTHIITLGNLRARFNI
MUL_3629|M.ulcerans_Agy99 LDYAAAISRTP-VAVSDELFAALRAHFDAAALVGLTHIITLGNLRARFNI
MAV_2020|M.avium_104 LEYATAISRTP-VEVSDELFDALRAHFDTAQLVGLTHVITLGNLRARFNI
Mb3360|M.bovis_AF2122/97 IAYAEAMTADP-HSVTDEQVADLRARFGEAGVIELTYQIGVENMRARMNS
Rv3327|M.tuberculosis_H37Rv IAYAEAMTADP-HSVTDEQVADLRARFGEAGVIELTYQIGVENMRARMNS
MAB_3677|M.abscessus_ATCC_1997 IAYADAMTGNP-HDITDEQVEDLRRRFGDAGVIELTYQIGVENMRARTYA
Mflv_4851|M.gilvum_PYR-GCK IDYAAAMTTDP-HTVSDEQVADLRRRFGDKGLMELTYQVGVENMRARMNA
Mvan_1576|M.vanbaalenii_PYR-1 IAYAAAMTTDP-HTVTDEQVADLRRRFGADGVIELTYQIGVENMRARMNA
TH_2184|M.thermoresistible__bu IAYADAMTTDP-HTVTDEQVADLRRRFGDAGVIELTTQIGVENMRARINT
MSMEG_6370|M.smegmatis_MC2_155 LALTEAVTEINRGPVSDDVYERAAAVFSERELSQLIAMIVTINAWNRINV
: : *:: ::*: *. : * : * *
MMAR_3686|M.marinum_M ALGIGSSGFSSDRVCALPEGAGPP-----------
MUL_3629|M.ulcerans_Agy99 ALGIGSSGFSSDRVCALPEGAGPP-----------
MAV_2020|M.avium_104 ALGIGSSGFSGNRVCALPDTPRP------------
Mb3360|M.bovis_AF2122/97 ALGITEQGFNSGDACRVPWAAPDVPSAESR-----
Rv3327|M.tuberculosis_H37Rv ALGITEQGFNSGDACRVPWAAPDVPSAESR-----
MAB_3677|M.abscessus_ATCC_1997 ALGITEQGFNSGDACRVPWAASPDPMGT-------
Mflv_4851|M.gilvum_PYR-GCK ALGITEQGFSSGDACRVPWTQ--------------
Mvan_1576|M.vanbaalenii_PYR-1 ALGITEQGFSSGDACRVPWASAAQAGQGATAAEKR
TH_2184|M.thermoresistible__bu ALGITEQGFSSGDACRIPWAARSDQPAGGPAGSR-
MSMEG_6370|M.smegmatis_MC2_155 TVKMP---FPRR-----------------------
:: : *