For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VGMTAPRTRRRTQTAPAGTVVAYVRVSTEEQAASGAGLDAQRAAIAAECDRRGWTVVGWYADEGVSGGKA LDARPALTAALNTVETAQAAVLMVAKSDRLARSLPTLLHVIDRAERAGGVVVAVDGTVDTSTAAGRFTTQ IMGSVAELERGLISDRTKAALAVRKAQGVRLGRPTTVPSSVVDRIAAERAAGATWAAIADGLNADGTPTG QGGSQWFPNTVARIAKRAVAVPAT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1493 | - | - | 100% (234) | Y4cG protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1612c | - | 6e-07 | 25.99% (227) | phiRv1 integrase |
| M. gilvum PYR-GCK | Mflv_1983 | - | 2e-34 | 43.84% (203) | resolvase domain-containing protein |
| M. tuberculosis H37Rv | Rv1586c | - | 7e-07 | 25.99% (227) | phiRv1 integrase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1820c | - | 5e-11 | 31.58% (190) | putative resolvase |
| M. marinum M | MMAR_4443 | - | 8e-38 | 45.67% (208) | site-specific recombinase |
| M. smegmatis MC2 155 | MSMEG_5002 | - | 5e-05 | 26.38% (235) | hypothetical protein MSMEG_5002 |
| M. thermoresistible (build 8) | TH_3340 | - | 4e-12 | 30.65% (186) | PUTATIVE putative Resolvase, N-terminal domain |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1448 | - | 5e-17 | 29.68% (219) | recombinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1983|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4443|M.marinum_M --------------------------------------------------
MAV_1493|M.avium_104 --------------------------------------------------
Mb1612c|M.bovis_AF2122/97 --------------------------------------------------
Rv1586c|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_1448|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1820c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3340|M.thermoresistible__bu --------------------------------------------------
MSMEG_5002|M.smegmatis_MC2_155 MKLHRLVLTNYRGITHREIEFPDHGVVVVSGANEIGKSSMIEALDLLIEA
Mflv_1983|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4443|M.marinum_M --------------------------------------------------
MAV_1493|M.avium_104 --------------------------------------------------
Mb1612c|M.bovis_AF2122/97 --------------------------------------------------
Rv1586c|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_1448|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1820c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3340|M.thermoresistible__bu --------------------------------------------------
MSMEG_5002|M.smegmatis_MC2_155 KDRSSKKEVKQVKPTHADVGAEVSAEISTGPYRFLYRKRFHKRAETQLTI
Mflv_1983|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4443|M.marinum_M --------------------------------------------------
MAV_1493|M.avium_104 --------------------------------------------------
Mb1612c|M.bovis_AF2122/97 --------------------------------------------------
Rv1586c|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_1448|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1820c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3340|M.thermoresistible__bu --------------------------------------------------
MSMEG_5002|M.smegmatis_MC2_155 LSPVREQLSGDEAHQRVLAMLAETVDTDLWQAQRVLQASSTAPVDLSGSD
Mflv_1983|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4443|M.marinum_M ----------------------------------------METKLFFGYS
MAV_1493|M.avium_104 --------------------------MGMTAPRTRRRTQTAPAGTVVAYV
Mb1612c|M.bovis_AF2122/97 -------------------------------------MRYTTPVRAAVYL
Rv1586c|M.tuberculosis_H37Rv -------------------------------------MRYTTPVRAAVYL
Mvan_1448|M.vanbaalenii_PYR-1 -------------------------------------------MRAVIYT
MAB_1820c|M.abscessus_ATCC_199 ----------------------------------MDTSTTADTGVLLGYA
TH_3340|M.thermoresistible__bu -----------------------------------------MTGQLVGYI
MSMEG_5002|M.smegmatis_MC2_155 ALARALDVAAGEAVSLSGDEPLLIERIEGEYQRYFTATGRPTGEWAAAVK
Mflv_1983|M.gilvum_PYR-GCK -MSTEDQADKRNGLEAQRAAIDAEAEWRGWDVE-HFADEGGSG-KHINPK
MMAR_4443|M.marinum_M RVSTDEQADSRNGLEAQRSAIDAEAARRGWAVE-HHADEGASG-KYINVN
MAV_1493|M.avium_104 RVSTEEQAASGAGLDAQRAAIAAECDRRGWTVVGWYADEGVSGGKALDAR
Mb1612c|M.bovis_AF2122/97 RIS-EDRSGEQLGVARQREDCLKLCGQRKWVPVEYLDN-DVSASTGKRRP
Rv1586c|M.tuberculosis_H37Rv RIS-EDRSGEQLGVARQREDCLKLCGQRKWVPVEYLDN-DVSASTGKRRP
Mvan_1448|M.vanbaalenii_PYR-1 RIS-DDQAGRGLGVARQLEDCQALADKLGWQVVNHFDDNDISAYSGKRRP
MAB_1820c|M.abscessus_ATCC_199 RVSTAHQSLDQQLDALTEAGVGPDR----------IYKDKLSGTSTREQR
TH_3340|M.thermoresistible__bu RVSTLDQNTERQLD-----GIDLDK----------VFTDKASGKDTN--R
MSMEG_5002|M.smegmatis_MC2_155 RLQAADAEVARCAAAVAEVDDAVHRHQELSAEVSRLAGECEQATQRLTAT
:. . ..
Mflv_1983|M.gilvum_PYR-GCK --LAEVLELLAMGQGEGLIVAKLDRLSRSI------------IHAATIIE
MMAR_4443|M.marinum_M --LQEALQLLAAGQGDGLIVAKLDRLARSV------------VHAANIIN
MAV_1493|M.avium_104 PALTAALNTVETAQAAVLMVAKSDRLARSL------------PTLLHVID
Mb1612c|M.bovis_AF2122/97 -AYEQMLADITAGKIAAVVAWDLDRLHRRP------------IELEAFMS
Rv1586c|M.tuberculosis_H37Rv -AYEQMLADITAGKIAAVVAWDLDRLHRRP------------IELEAFMS
Mvan_1448|M.vanbaalenii_PYR-1 -GFEAMLEAMKAGQFDALLCFHTDRLYRNM------------SDLERVIE
MAB_1820c|M.abscessus_ATCC_199 PGLAALLDYARPG--DGIVVVGIDRLGRNA------------AEVMATIR
TH_3340|M.thermoresistible__bu PALDECLRYVREG--DTLIVHSMDRLARSL------------PDLRRLVD
MSMEG_5002|M.smegmatis_MC2_155 RTAADAVDALRQQLKEAQVVAEAAHVTHAASVAALTERRRMRAEIDERAA
: : :: :
Mflv_1983|M.gilvum_PYR-GCK CAQKQGWSL-VLLDL---GVDLTTAAGRMFAMNLVNYAQYERELISERTK
MMAR_4443|M.marinum_M AAQAQGWSL-VVLDI---NLDLSTAAGRMMARTLVNFAEYERELISERTK
MAV_1493|M.avium_104 RAERAGGVV-VAVDG---TVDTSTAAGRFTTQIMGSVAELERGLISDRTK
Mb1612c|M.bovis_AF2122/97 LADEKRLAL-ATVAG---DVDLATPQGRLVARLKGSVAAHETEHKKARQR
Rv1586c|M.tuberculosis_H37Rv LADEKRLAL-ATVAG---DVDLATPQGRLVARLKGSVAAHETEHKKARQR
Mvan_1448|M.vanbaalenii_PYR-1 LADARRVEI-RTVQGG--TLDLSTSAGRMVARILGSVARQESEHSSERRK
MAB_1820c|M.abscessus_ATCC_199 DLAEREIVLHSLREGI----DSSNATGRMIAGVLASLAELELELGRERRA
TH_3340|M.thermoresistible__bu ELTARGVAVRFVKEGLTFTRDESDPCSVLMLSVMGAVAEFERSLMLQRQR
MSMEG_5002|M.smegmatis_MC2_155 TITELQAALVTAAEEAETAREVVTAAEEEAERAKAAVADHEARVDAARAA
: : . * * *
Mflv_1983|M.gilvum_PYR-GCK VALAAKRARG----------------------------------------
MMAR_4443|M.marinum_M AGLAAKKARG----------------------------------------
MAV_1493|M.avium_104 AALAVRKAQG----------------------------------------
Mb1612c|M.bovis_AF2122/97 RAARQKAERGH--------------------------------PNWSKAF
Rv1586c|M.tuberculosis_H37Rv RAARQKAERGH--------------------------------PNWSKAF
Mvan_1448|M.vanbaalenii_PYR-1 RANVQRAANG----------------------------------DWVAAR
MAB_1820c|M.abscessus_ATCC_199 AARESRRARG----------------------------------------
TH_3340|M.thermoresistible__bu EGIAIAKAKG----------------------------------------
MSMEG_5002|M.smegmatis_MC2_155 VERLSDRDEADRLDMRLAKIDAATRELQAVTDELKTITLDDTAMRAIEKA
..
Mflv_1983|M.gilvum_PYR-GCK -----ERIGRPRLAKPGVVRRIVMDRNAGLSFARIANALEAEGILSPAGL
MMAR_4443|M.marinum_M -----ERIGRPRLATAGVVRRIVLDRNAGLSFGRIARALEAEAILSPAGR
MAV_1493|M.avium_104 -----VRLGRPTTVPSSVVDRIAAERAAGATWAAIADGLNADGTPTGQGG
Mb1612c|M.bovis_AF2122/97 GYLPGPNGPEPDPRTAPLVKQAYADILAGASLGDVCRQWNDAG-AFTITG
Rv1586c|M.tuberculosis_H37Rv GYLPGPNGPEPDPRTAPLVKQAYADILAGASLGDVCRQWNDAG-AFTITG
Mvan_1448|M.vanbaalenii_PYR-1 RPFGYTMDGEPLEPEATAIRSAITDVLSGKSVRAVARDWNDAGLATTGKA
MAB_1820c|M.abscessus_ATCC_199 -----QHIGRPKALDNAKAALAQRMHLAGEPVLTIANTLGVSR-------
TH_3340|M.thermoresistible__bu -----VYKGRKPALSDAQAAEVAQRLSAGESATELAREYGVSR-------
MSMEG_5002|M.smegmatis_MC2_155 ALAVERAAGQAELASARIELVAQNGLDVRVDDATVALQAGAEWSVSTTTR
. :.
Mflv_1983|M.gilvum_PYR-GCK PTWQSSTVRRIYQSATVTTEMEKTA-------------------------
MMAR_4443|M.marinum_M PSWQASTVRRIYQSAIAASELEVAS-------------------------
MAV_1493|M.avium_104 SQWFPNTVARIAKRAVAVPAT-----------------------------
Mb1612c|M.bovis_AF2122/97 RPWTTTTLSKFLRKPRNAGLRAYKGARYGPVDRDAIVGKAQWSPLVDEAT
Rv1586c|M.tuberculosis_H37Rv RPWTTTTLSKFLRKPRNAGLRAYKGARYGPVDRDAIVGKAQWSPLVDEAT
Mvan_1448|M.vanbaalenii_PYR-1 DKWTATSVRRVLLRPRYAALVVHQGK---------VVGPGSWTPLIDTDT
MAB_1820c|M.abscessus_ATCC_199 -----ATVYRVLAEDLHAGKEDQ---------------------------
TH_3340|M.thermoresistible__bu -----ATVYNVRNRARGAA-------------------------------
MSMEG_5002|M.smegmatis_MC2_155 TEIDVPGVLSVRVVPGTPAAETQARLDDAQAVLTAALQAVGAESVDVARA
: .
Mflv_1983|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4443|M.marinum_M --------------------------------------------------
MAV_1493|M.avium_104 --------------------------------------------------
Mb1612c|M.bovis_AF2122/97 FWAAQAVLDAPGRAPGRKSVRRHLLTGLAGCGKCGNHLAGSYRTDG----
Rv1586c|M.tuberculosis_H37Rv FWAAQAVLDAPGRAPGRKSVRRHLLTGLAGCGKCGNHLAGSYRTDG----
Mvan_1448|M.vanbaalenii_PYR-1 HHGIVAYLNDPARKGKVGFERKYQGSGVYRCGVCGTPVITHMSSGGSPNR
MAB_1820c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3340|M.thermoresistible__bu --------------------------------------------------
MSMEG_5002|M.smegmatis_MC2_155 LDARRRELLGSRDRLRATLDALVGDDDIARLRDRLAALRAGQTDDGGLFD
Mflv_1983|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4443|M.marinum_M --------------------------------------------------
MAV_1493|M.avium_104 --------------------------------------------------
Mb1612c|M.bovis_AF2122/97 --QVVYVCKACHGVAILADNIEPILYHIVAERLAMPDAVDLLR-REIHDA
Rv1586c|M.tuberculosis_H37Rv --QVVYVCKACHGVAILADNIEPILYHIVAERLAMPDAVDLLR-REIHDA
Mvan_1448|M.vanbaalenii_PYR-1 VARRAYACPNGFHVRRQGDGLDTYVDTIVIGRLSQPDAAELLSTLSNSEG
MAB_1820c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3340|M.thermoresistible__bu --------------------------------------------------
MSMEG_5002|M.smegmatis_MC2_155 VEGPADIDTARAQLAADVAAHREAVAHCETARKAVAVAAARDTEKSTRLS
Mflv_1983|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4443|M.marinum_M --------------------------------------------------
MAV_1493|M.avium_104 --------------------------------------------------
Mb1612c|M.bovis_AF2122/97 AEAETIRLELETLYGELDRLAVERAEGLLTARQVKISTDIVNAKITKLQA
Rv1586c|M.tuberculosis_H37Rv AEAETIRLELETLYGELDRLAVERAEGLLTARQVKISTDIVNAKITKLQA
Mvan_1448|M.vanbaalenii_PYR-1 VDIGALHAQRTALQARQEELASLFADGAISAPQLKLGSAKLTNALETLER
MAB_1820c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3340|M.thermoresistible__bu --------------------------------------------------
MSMEG_5002|M.smegmatis_MC2_155 VLREKLTAAQTELTTCSARLEAQRAGTPDEALALKVQADDEQAKATAARV
Mflv_1983|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4443|M.marinum_M --------------------------------------------------
MAV_1493|M.avium_104 --------------------------------------------------
Mb1612c|M.bovis_AF2122/97 RQQDQER---LRVFDGIPLGTPQVAGMIAELSPDRFRAVLDVLAEVVVQP
Rv1586c|M.tuberculosis_H37Rv RQQDQER---LRVFDGIPLGTPQVAGMIAELSPDRFRAVLDVLAEVVVQP
Mvan_1448|M.vanbaalenii_PYR-1 DLAAATQGNPASALLQDVNGVAQLEGRWAELSPDLRGKVIDQLMTVTINR
MAB_1820c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3340|M.thermoresistible__bu --------------------------------------------------
MSMEG_5002|M.smegmatis_MC2_155 ATLRDELDRSAPDSVLAELADAQRHAQSVQTRHDAATEGLREVSAQLKVY
Mflv_1983|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4443|M.marinum_M --------------------------------------------------
MAV_1493|M.avium_104 --------------------------------------------------
Mb1612c|M.bovis_AF2122/97 VGKSGRIFNPERVQVNWR--------------------------------
Rv1586c|M.tuberculosis_H37Rv VGKSGRIFNPERVQVNWR--------------------------------
Mvan_1448|M.vanbaalenii_PYR-1 SPKGLRRFDPDYVTVDWKQG------------------------------
MAB_1820c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3340|M.thermoresistible__bu --------------------------------------------------
MSMEG_5002|M.smegmatis_MC2_155 GTEGRKGQLDEAETEREHANAEYLRVHRRARAAELLRSVMTRHRDATRQR
Mflv_1983|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4443|M.marinum_M --------------------------------------------------
MAV_1493|M.avium_104 --------------------------------------------------
Mb1612c|M.bovis_AF2122/97 --------------------------------------------------
Rv1586c|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_1448|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1820c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3340|M.thermoresistible__bu --------------------------------------------------
MSMEG_5002|M.smegmatis_MC2_155 YVDPFRNEVQRLGRLVFGEDFEVDVDSKLRISTRTVSGRTVPYESLSGGA
Mflv_1983|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4443|M.marinum_M --------------------------------------------------
MAV_1493|M.avium_104 --------------------------------------------------
Mb1612c|M.bovis_AF2122/97 --------------------------------------------------
Rv1586c|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_1448|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_1820c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3340|M.thermoresistible__bu --------------------------------------------------
MSMEG_5002|M.smegmatis_MC2_155 KEQLAIVARLAGASLVAKEDTVPVIIDDALGFTDADRLTKMGAVFDAVGG
Mflv_1983|M.gilvum_PYR-GCK ---------------------------
MMAR_4443|M.marinum_M ---------------------------
MAV_1493|M.avium_104 ---------------------------
Mb1612c|M.bovis_AF2122/97 ---------------------------
Rv1586c|M.tuberculosis_H37Rv ---------------------------
Mvan_1448|M.vanbaalenii_PYR-1 ---------------------------
MAB_1820c|M.abscessus_ATCC_199 ---------------------------
TH_3340|M.thermoresistible__bu ---------------------------
MSMEG_5002|M.smegmatis_MC2_155 DGQVIVLTCSPDRYASVHGAHHIALTA