For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. avium 104 MAV_1272 (-)

MSTEQTTSPAAQRESAAPRRTGTRGWGGWVAGAGLAAFALFFIANCRVALDPRVANPNVQGRPRPVKFIF
GLDYMTFIQISTVVMLIVLVVVFVRGWRRNPGSPAMLMFLCTTLIVWQDPIMNWAPFAVYNPDLIHWPES
WPLVSLSPTVEPFVVFGYVTFYFGPYFPAVWILRRLQAKYGPQSFFARHPLVSLGVLTCAIGFVFDAWLE
IQLVHMGMYIYSQVIPWGSVFTGTTFQFPLIWESFSVTFVMVPAAILCYRDDTGKSVAEKLAAKAKLFPA
RPVLGTFLVMFVIINVSYFAYGAWFAVIKATKAATSVACPWPYPEAKVYDPQGFYEKAGAQGPYSVGIWS
TWMSGQPHGRPDVQPPPPGAGACATTAVGHG

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. avium 104	MAV_1272	-	-	100% (381)	hypothetical protein MAV_1272
M. avium 104	MAV_2134	-	9e-12	27.85% (219)	hypothetical protein MAV_2134
M. avium 104	MAV_1951	-	3e-09	25.41% (244)	postpolyketide modification protein, putative

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	-	-	-	-	-
M. gilvum PYR-GCK	Mflv_4153	-	1e-164	68.78% (378)	hypothetical protein Mflv_4153
M. tuberculosis H37Rv	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	-	-	-	-	-
M. marinum M	-	-	-	-	-
M. smegmatis MC2 155	MSMEG_6808	-	6e-11	28.52% (277)	hypothetical protein MSMEG_6808
M. thermoresistible (build 8)	-	-	-	-	-
M. ulcerans Agy99	-	-	-	-	-
M. vanbaalenii PYR-1	Mvan_4195	-	0.0001	30.36% (112)	hypothetical protein Mvan_4195

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_6808|M.smegmatis_MC2_155      ---------------------MSELSDKKAAATESLRSVGRLDAPPAAKP
Mvan_4195|M.vanbaalenii_PYR-1       MQPAGSAAPPTASTIVKGKPIMSDLS-RKPAVTESVSGTADLGKQGPSQ-
MAV_1272|M.avium_104                -----------------------MSTEQTTS--PAAQRESAAPRRTGTRG
Mflv_4153|M.gilvum_PYR-GCK          -----------------------MTTQKAGAPLPQAKPDAGASPRKGPN-
                                                             : :  :        .       .. 

MSMEG_6808|M.smegmatis_MC2_155      SRRVKIWATAGGIILAFQIYVWIRWITGPYFTRVDPGPTDPPTFMKIA-L
Mvan_4195|M.vanbaalenii_PYR-1       SNAFKVWATVGAVFLAYTLYVFIRWVSGPYFEPVAGGPSEPPLYMKIP-L
MAV_1272|M.avium_104                WGGWVAGAGLAAFALFFIANCRVALDPRVANPNVQGRPRPVKFIFGLD-Y
Mflv_4153|M.gilvum_PYR-GCK          WGRWISAFALLGFFGLFTAFSRTELDPRVANPNVEGRPRPVEFLFGWDGW
                                               ..   :         .      *   *      :     

MSMEG_6808|M.smegmatis_MC2_155      MMWQIGSPVLFPVAIWWFIIRPWRRERRITLDGMIMVSTGLFFFQDPLLN
Mvan_4195|M.vanbaalenii_PYR-1       MANAVVLWIGLPFALWFFLIRPWVREKRITLDGMLLVSMGLMMFQDPMLN
MAV_1272|M.avium_104                MTFIQISTVVMLIVLVVVFVRGWRRNPGSPAMLMFLCTT-LIVWQDPIMN
Mflv_4153|M.gilvum_PYR-GCK          LWVHQIGCVILLVVLVAIFVRGWRRDPGSPVMLMFLCTT-LIVWQDPIMN
                                    :       : : ..:  .::* * *:   .   *:: :  *:.:***::*

MSMEG_6808|M.smegmatis_MC2_155      YINTWCTYNAWAFNMGSWAPHVPGWMSPEKPGAQVAEPLGINVSGYAYGV
Mvan_4195|M.vanbaalenii_PYR-1       YYSTWCTYNAWLFNQGSWAPHIPGWVAHEEPGHTVPEPLLTNIPGYMYGV
MAV_1272|M.avium_104                ----WAPFAVYNPDLIHWPESWP--LVSLSP--TVEPFVVFGYVTFYFGP
Mflv_4153|M.gilvum_PYR-GCK          ----WAPFAVYNPELLHWPENWP--LIMLSP--TVEPFIVFGYVAFYFAP
                                        *..: .:  :   *.   *  :   .*   *   :  .   : :. 

MSMEG_6808|M.smegmatis_MC2_155      LLCTILGCWIMRKAQQRWPNLGTKGLIGV---AFAWGFVFDFVMEGLVLM
Mvan_4195|M.vanbaalenii_PYR-1       LLLTIVGCALMRKIKNRWPGISNLRLVLV---TYAVAIVFDFIMEGLILL
MAV_1272|M.avium_104                YFPAVWILRRLQAKYGPQSFFARHPLVSLGVLTCAIGFVFDAWLE-IQLV
Mflv_4153|M.gilvum_PYR-GCK          FFPAIWCLRKLQAKHGPTAFVSRHPLISLGALTLVIGFIFDAILE-VSLV
                                     : ::     ::      . ..   *: :   : . .::**  :* : *:

MSMEG_6808|M.smegmatis_MC2_155      PLGMYTFPGAIQSLSINAGTYYQWPIYEGLMWGGVQAALCCLRFFTDDRG
Mvan_4195|M.vanbaalenii_PYR-1       PIGFYSYPGAIQELSINAGTYYQYPIYEGFMWGGVQAALCCLRFFTDDRG
MAV_1272|M.avium_104                HMGMYIYSQVIPWGSVFTGTTFQFPLIWESFSVTFVMVPAAILCYRDDTG
Mflv_4153|M.gilvum_PYR-GCK          RTGLYIYSQAIPFGTLFPGTTFQFPLIWESLAVTFVMVPAAVLCYRDDTG
                                      *:* :. .*   :: .** :*:*:    :   .  . ..:  : ** *

MSMEG_6808|M.smegmatis_MC2_155      RTVVEKGLDNVRGGFAKQQLVRFLAIFAAISASFFTF---YIVPAQFMST
Mvan_4195|M.vanbaalenii_PYR-1       RTVVERGLDRVRGGFVKQQFVRFLAIFGGVSACFFLF---YNVPATWLGM
MAV_1272|M.avium_104                KSVAEKLAAKAKLFPARPVLGTFLVMFVIINVSYFAYGAWFAVIKATKAA
Mflv_4153|M.gilvum_PYR-GCK          KAVAEKLAARAKLFPSKPVLGTFLVMFFIINIAYFAYGSWFAAIKASGLA
                                    ::*.*:   ..:    :  :  **.:*  :. .:* :   : .       

MSMEG_6808|M.smegmatis_MC2_155      HADPWPEDVQKRSYFTSGICGDGTDRPCPHPDLPIPTKHSGYINVDGELV
Mvan_4195|M.vanbaalenii_PYR-1       QGDPWPEDVQKRSYFNPGICGEGTDRPCPNPDLPLPTKHSGYVNHDGELV
MAV_1272|M.avium_104                TSVACPWPYPEAKVYDPQGFYEKAGAQGPYSVGIWSTWMSGQPHGRPDVQ
Mflv_4153|M.gilvum_PYR-GCK          TAVACPWPYPEAKVYDPQGYFEKEGAQGPFSVGKWATWQSGLPNGRPEVT
                                     . . *    : . : .    :  .   * .    .*  **  :   :: 

MSMEG_6808|M.smegmatis_MC2_155      LPEGVEMPAVVPHE--------
Mvan_4195|M.vanbaalenii_PYR-1       LPEGVEIPPVVPIQRPNSDDSQ
MAV_1272|M.avium_104                PPPPGAGACATTAVGHG-----
Mflv_4153|M.gilvum_PYR-GCK          PPPPGEGDCAPENADG------
                                     *       .