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EGQLAQVSLRPDSKTVFMVLRDPAADMSLTVTCPRDLVLNAPVKLAEGTQVVVCGKPSFYTGRGTFSLRL SEIRAVGVGELLARIERLRRLLDAEGLFDPRLKRPIPFLPNMIGLITGRASAAERDVKTVAAGRWPAVRF AVRNTAVQGPNAVAQIVEALRELDRDPEVDVIVLARGGGSVEDLLPFSDETLCRAIAACRTPVISAVGHE PDNPLCDLVADVRAATPTDAAKKVVPDTAAEQRLIDDLRRRSAQALRNWVSREQRALAQIRSRPVLAEPL RALTARAEEVHRARSAIRRDVTRLTAAETERIGHLRARLATLGPAATLARGYAVVQTVGAGGPHVLRTVG DAPAGTRLRVRVADGAVAALSEGPTDGE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1228 | xseA | - | 100% (379) | exodeoxyribonuclease VII large subunit |
| M. avium 104 | MAV_2593 | - | 8e-05 | 26.10% (249) | acyl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1138c | xseA | 0.0 | 85.42% (384) | exodeoxyribonuclease VII large subunit |
| M. gilvum PYR-GCK | Mflv_2077 | xseA | 1e-170 | 78.13% (375) | exodeoxyribonuclease VII large subunit |
| M. tuberculosis H37Rv | Rv1108c | xseA | 0.0 | 85.42% (384) | exodeoxyribonuclease VII large subunit |
| M. leprae Br4923 | MLBr_01940 | xseA | 1e-176 | 80.63% (382) | exodeoxyribonuclease VII large subunit |
| M. abscessus ATCC 19977 | MAB_1255c | - | 1e-161 | 77.33% (375) | exodeoxyribonuclease VII large subunit XseA |
| M. marinum M | MMAR_4357 | xseA | 0.0 | 86.84% (380) | exodeoxyribonuclease VII (large subunit) XseA |
| M. smegmatis MC2 155 | MSMEG_5226 | xseA | 1e-173 | 79.74% (380) | exodeoxyribonuclease VII large subunit |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0170 | xseA | 0.0 | 86.05% (380) | exodeoxyribonuclease VII large subunit |
| M. vanbaalenii PYR-1 | Mvan_4633 | xseA | 1e-172 | 79.20% (375) | exodeoxyribonuclease VII large subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1138c|M.bovis_AF2122/97 ---------------MTQNSAENPFPVRAVAIRVAGWIDKLGAVWVEGQL
Rv1108c|M.tuberculosis_H37Rv ---------------MTQNSAENPFPVRAVAIRVAGWIDKLGAVWVEGQL
MLBr_01940|M.leprae_Br4923 MTEAVPTDSVDSKASSQVNSAENPFPVRAVALRIAGWIDKLGTVWVEGQL
MAV_1228|M.avium_104 ---------------------------------------------MEGQL
MMAR_4357|M.marinum_M -----------MSPAAASNSAENPFPVRAVAIRVAGWIDRLGTVWVEGQL
MUL_0170|M.ulcerans_Agy99 -----------MSPAAASNSAENPFPVRAVAIRVAGWIDRLGTVWVEGQL
MAB_1255c|M.abscessus_ATCC_199 -------------MADPGTSPENPWPVRAVATRVAKWIDRLGQVWVEGQL
Mflv_2077|M.gilvum_PYR-GCK -------MTSARADGTPGQSADNPFPVRGVAIRVAGWIDKLGAVWVEGQI
Mvan_4633|M.vanbaalenii_PYR-1 -------MTSA-----QGHSPENPFPVRGVAIRVAGWIDKLGAVWVEGQI
MSMEG_5226|M.smegmatis_MC2_155 --------------------------MRAVATRVAKWIDRLGVVWVEGQL
:***:
Mb1138c|M.bovis_AF2122/97 AQITMRPDAKTVFMVLRDPAADMSLTVTCSRDLVLSAPVKLAEGVQVVVC
Rv1108c|M.tuberculosis_H37Rv AQITMRPDAKTVFMVLRDPAADMSLTVTCSRDLVLSAPVKLAEGVQVVVC
MLBr_01940|M.leprae_Br4923 AQITMRPNAKTVFMVLRDPAADISLIVTCSRDFVLRAPVKLAEGIQVVVC
MAV_1228|M.avium_104 AQVSLRPDSKTVFMVLRDPAADMSLTVTCPRDLVLNAPVKLAEGTQVVVC
MMAR_4357|M.marinum_M AQITIRPNSKTVFMVLRDPAADMSLTVTCPRDLVLSAPVKLTEGTQVVVC
MUL_0170|M.ulcerans_Agy99 AQITIRPNSKTVFMVLRDPAADMSLTVTCPRDLVLSAPVKLTEGTQVVVC
MAB_1255c|M.abscessus_ATCC_199 TQIDVRPGSRTVFMVLRDPAADMSLTVTCPPDMVRNAPVKLTEGTQVVVC
Mflv_2077|M.gilvum_PYR-GCK AQLTLRPNSNTAFITLRDPAADMSLSLTCPRDLVVNAPVKMSDGTQVIVY
Mvan_4633|M.vanbaalenii_PYR-1 AQLTLRPNSSTAFITLRDPAADMSLSLTCPRDLVVNAPVKMTDGTQVIVY
MSMEG_5226|M.smegmatis_MC2_155 TELKIRPDSKTVFMVLRDPAADMSLTLTCPRDLVRNAPVRLTEGTQVIIC
::: :**.: *.*:.*******:** :**. *:* ***::::* **::
Mb1138c|M.bovis_AF2122/97 GKPSFYTGRGTFSLRLSEIRAVGIGELLARIDRLRRLLDAEGLFDPRLKR
Rv1108c|M.tuberculosis_H37Rv GKPSFYTGRGTFSLRLSEIRAVGIGELLARIDRLRRLLDAEGLFDPRLKR
MLBr_01940|M.leprae_Br4923 GKPSFYIGRGTFSLRLSDIRAVGIGELLVRIDRLRRLLDSEGLFDPRLKR
MAV_1228|M.avium_104 GKPSFYTGRGTFSLRLSEIRAVGVGELLARIERLRRLLDAEGLFDPRLKR
MMAR_4357|M.marinum_M GKPSFYTGRGTFSLRLNEIRAVGVGELLARIERLRRLLDAEGLFDPRLKR
MUL_0170|M.ulcerans_Agy99 GKPSFYTGRGTFSLRLNEIRAVGVGELLARIERLRRLLDAEGLFDPRLKR
MAB_1255c|M.abscessus_ATCC_199 GKPTFYTGRGSFSLRLSEIRAVGIGELLARIERLRQLLAAEGLFDARLKR
Mflv_2077|M.gilvum_PYR-GCK GKPSFYTGRGTFSLRVSEIRAVGIGELLARIERLRRLLDAEGLFDPRLKR
Mvan_4633|M.vanbaalenii_PYR-1 GKPNFYTGRGTFSLRVSEIRAVGIGELLARIERLRRLLDTEGLFDPRLKR
MSMEG_5226|M.smegmatis_MC2_155 GKPNFYTGRGTFSLRVSEIRAVGIGELLARIERLRRLLDAEGLFDPRLKR
***.** ***:****:.:*****:****.**:***:** :*****.****
Mb1138c|M.bovis_AF2122/97 PIPYLPNMIGLITGRASAAERDVTTVASARWPAARFAVRNVAVQGPNAVG
Rv1108c|M.tuberculosis_H37Rv PIPYLPNMIGLITGRASAAERDVTTVASARWPAARFAVRNVAVQGPNAVG
MLBr_01940|M.leprae_Br4923 PIPFLPNMIGIITGRASAAERDVTTVASARWPAARFAIRNTAVQGPNAVS
MAV_1228|M.avium_104 PIPFLPNMIGLITGRASAAERDVKTVAAGRWPAVRFAVRNTAVQGPNAVA
MMAR_4357|M.marinum_M PIPFLPNTVGLITGRASAAERDVTTVAATRWPAVRFAVRNTAVQGPNAVA
MUL_0170|M.ulcerans_Agy99 PIPFLPNTVGLITGRASAAERDVTTAAATRWPAVRFAVRNTAVQGPNAVA
MAB_1255c|M.abscessus_ATCC_199 PVPFLPARIGLITGRASAAEHDVTSVATTRWPAVQFAIRNTPVQGPHAVA
Mflv_2077|M.gilvum_PYR-GCK PIPFLPDTIGLITGRASAAEHDIVAVASGRWPAVRFAVRHTVVQGPNAVP
Mvan_4633|M.vanbaalenii_PYR-1 PIPFLPGTIGLITGRASAAEHDIVAVATGRWPAVRFAVRNTVVQGPNAVP
MSMEG_5226|M.smegmatis_MC2_155 SIPFLPNTIGLITGRASAAERDVTTVASSRWPAVRFAIRNTIVQGPNAVP
.:*:** :*:*********:*: :.*: ****.:**:*:. ****:**
Mb1138c|M.bovis_AF2122/97 QIVEALRELDRDPDVDVIVLARGGGSVEDLLPFSDETLCRAIAACRTPVV
Rv1108c|M.tuberculosis_H37Rv QIVEALRELDRDPDVDVIVLARGGGSVEDLLPFSDETLCRAIAACRTPVV
MLBr_01940|M.leprae_Br4923 QIVEALRELDRNVDVEVIVVARGGGSVEDLLTFSDETLCRAIAACRTPVI
MAV_1228|M.avium_104 QIVEALRELDRDPEVDVIVLARGGGSVEDLLPFSDETLCRAIAACRTPVI
MMAR_4357|M.marinum_M QIVEALRELDSDLEVDVIVVARGGGSVEDLLPFSDETLCRAIAACRTPVI
MUL_0170|M.ulcerans_Agy99 QIVEALRELDSDLEVDVIVVARGGGSVEDLLLFSDETLCRAIAACRTPVI
MAB_1255c|M.abscessus_ATCC_199 EIVAALQALDADPSVDVIVLARGGGSVEDLLPFSDETLCRAISACRTPVV
Mflv_2077|M.gilvum_PYR-GCK QIVDALRALDADPDVDVIVLARGGGSVEDLLPFSDETLCREIARCTTPVV
Mvan_4633|M.vanbaalenii_PYR-1 QIVDALRDLDADPDVDVIVLARGGGSVEDLLPFSDETLCREIAACTTPVV
MSMEG_5226|M.smegmatis_MC2_155 QIVDALAALDADPEVDVIVLARGGGSVEDLLPFSDETLCRAISACRTPVV
:** ** ** : .*:***:*********** ******** *: * ***:
Mb1138c|M.bovis_AF2122/97 SAVGHEPDNPLCDLVVDLRAATPTDAAKKVVPDTAAEQRLIDDLRRRSAQ
Rv1108c|M.tuberculosis_H37Rv SAVGHEPDNPLCDLVVDLRAATPTDAAKKVVPDTAAEQRLIDDLRRRSAQ
MLBr_01940|M.leprae_Br4923 SAVGHEPDNPLCDLVADLRAATPTDAAKKVVPDAAVEQRLIEDLQRRSAQ
MAV_1228|M.avium_104 SAVGHEPDNPLCDLVADVRAATPTDAAKKVVPDTAAEQRLIDDLRRRSAQ
MMAR_4357|M.marinum_M SAVGHEPDNPLCDLVADLRAATPTDAAKKAVPDTAAEQRLVADLRRRSAQ
MUL_0170|M.ulcerans_Agy99 SAVGHEPDNPLCDLVADLRAATPTDAAKKAVPDTAAEQRLVADLRRRSAQ
MAB_1255c|M.abscessus_ATCC_199 SAVGHEPDNPLSDLVADLRAATPTDAAKKLVPDAAAEQALILDLRRRSAQ
Mflv_2077|M.gilvum_PYR-GCK SAIGHEPDNPLCDLVADLRAATPTDAAKRIVPDTAAEQALITDLRRRSAR
Mvan_4633|M.vanbaalenii_PYR-1 SAIGHEPDNPLCDLVADLRAATPTDAAKRIVPDTAAEQALVTDLRRRSAR
MSMEG_5226|M.smegmatis_MC2_155 SAIGHEPDNPVCDLVADLRAATPTDAAKRIVPDAAAEQALISDLHRRSAR
**:*******:.***.*:**********: ***:*.** *: **:****:
Mb1138c|M.bovis_AF2122/97 ALRNWVSREQRAVAQLRSRPVLADPMTMVSVRAEEVHRARSTLRRNLTLM
Rv1108c|M.tuberculosis_H37Rv ALRNWVSREQRAVAQLRSRPVLADPMTMVSVRAEEVHRARSTLRRNLTLM
MLBr_01940|M.leprae_Br4923 ALRNWVSREQRTLVQLRSRPVLAEPLRTLTTRSEEIHRAQSAIRREIIRL
MAV_1228|M.avium_104 ALRNWVSREQRALAQIRSRPVLAEPLRALTARAEEVHRARSAIRRDVTRL
MMAR_4357|M.marinum_M ALRNWVSREQRALTQLRSRPVLADPLKALITRSDEIQRARSALRRDVSRL
MUL_0170|M.ulcerans_Agy99 ALRNWVSREQRALTQLRSHPVLADPLKALITRSDEIQRARSALRRDVSRL
MAB_1255c|M.abscessus_ATCC_199 ALRNWVQREQRGLDQVRSRPVLADPLRMVSVRQDEIDGARNALRRDVRRL
Mflv_2077|M.gilvum_PYR-GCK ALRNWVNRETHVVTQLRSRPVMSRPLAAIDARSDEIHRARAAVRRDITRL
Mvan_4633|M.vanbaalenii_PYR-1 ALRNWVNREAHTVAQLRSRPVLARPLAAIDARAEEIHRARAAARRDVKRL
MSMEG_5226|M.smegmatis_MC2_155 ALRNWVHREQHHLDQLRSRPVLAQPLAAITARGDEIHRARATAQRDITRL
****** ** : : *:**:**:: *: : .* :*:. *: : :*:: :
Mb1138c|M.bovis_AF2122/97 VAAETERIGHLAARLATLGPAATLARGYAIVQTVAQTGPEGGSEPQVLRS
Rv1108c|M.tuberculosis_H37Rv VAAETERIGHLAARLATLGPAATLARGYAIVQTVAQTGPEGGSEPQVLRS
MLBr_01940|M.leprae_Br4923 VTTETERVGHLATQLATLGPAATLARGYAIVQALEDG--TQTVTAAVLRS
MAV_1228|M.avium_104 TAAETERIGHLRARLATLGPAATLARGYAVVQTVGAG------GPHVLRT
MMAR_4357|M.marinum_M ISTETENIGHLGARLATLGPAATLARGYAVVQTVSTAG----QPMEVLRS
MUL_0170|M.ulcerans_Agy99 ISTETENIGHLGARLATLGPAATLARGYAVVQTVSTAG----QPMEVLRS
MAB_1255c|M.abscessus_ATCC_199 VDIESQRVEHLTARLTTLGPAATLARGYSVVQRVRDDG-----TVEVLRT
Mflv_2077|M.gilvum_PYR-GCK VGIESDRIGHLSARLTTLGPAATLARGYAVVQTIPESG-----EPRILGS
Mvan_4633|M.vanbaalenii_PYR-1 LATEADRVGHLTARLTTLGPAATLARGYAVVQTIATSG-----EPHVLHS
MSMEG_5226|M.smegmatis_MC2_155 IAGETDTIGHLSARLTALGPAATLARGYAVVQAVPDTG-----PPTVLRS
*:: : ** ::*::***********::** : :* :
Mb1138c|M.bovis_AF2122/97 VHDAPEGTKLRVRVADGALAAVSEGQTNGL-----
Rv1108c|M.tuberculosis_H37Rv VHDAPEGTKLRVRVADGALAAVSEGQTNGL-----
MLBr_01940|M.leprae_Br4923 VDDAPTGTRLRVRVSDGAIVAVSEGRADGP-----
MAV_1228|M.avium_104 VGDAPAGTRLRVRVADGAVAALSEGPTDGE-----
MMAR_4357|M.marinum_M VDGAPAGTRLRVRVGDGAVTAVSEGRVDGA-----
MUL_0170|M.ulcerans_Agy99 VDGAPAGTRLRVRVGDGAVTAVSEGRVDGA-----
MAB_1255c|M.abscessus_ATCC_199 VADAPVGAPLRVRVSDGAVTATVTGEDS-------
Mflv_2077|M.gilvum_PYR-GCK VDDAPAGTRLRVRVADGAITATSEGGQ--------
Mvan_4633|M.vanbaalenii_PYR-1 VSDAPAGARLRIRVTDGAVTAISEGSE--------
MSMEG_5226|M.smegmatis_MC2_155 TDDAPAGTRLRVRVSDGVVTARSEGTEDDETGSST
. .** *: **:** **.:.* *