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VRAVATRVAKWIDRLGVVWVEGQLTELKIRPDSKTVFMVLRDPAADMSLTLTCPRDLVRNAPVRLTEGTQ VIICGKPNFYTGRGTFSLRVSEIRAVGIGELLARIERLRRLLDAEGLFDPRLKRSIPFLPNTIGLITGRA SAAERDVTTVASSRWPAVRFAIRNTIVQGPNAVPQIVDALAALDADPEVDVIVLARGGGSVEDLLPFSDE TLCRAISACRTPVVSAIGHEPDNPVCDLVADLRAATPTDAAKRIVPDAAAEQALISDLHRRSARALRNWV HREQHHLDQLRSRPVLAQPLAAITARGDEIHRARATAQRDITRLIAGETDTIGHLSARLTALGPAATLAR GYAVVQAVPDTGPPTVLRSTDDAPAGTRLRVRVSDGVVTARSEGTEDDETGSST
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5226 | xseA | - | 100% (404) | exodeoxyribonuclease VII large subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1138c | xseA | 1e-176 | 76.19% (399) | exodeoxyribonuclease VII large subunit |
| M. gilvum PYR-GCK | Mflv_2077 | xseA | 0.0 | 80.71% (394) | exodeoxyribonuclease VII large subunit |
| M. tuberculosis H37Rv | Rv1108c | xseA | 1e-176 | 76.19% (399) | exodeoxyribonuclease VII large subunit |
| M. leprae Br4923 | MLBr_01940 | xseA | 1e-169 | 73.50% (400) | exodeoxyribonuclease VII large subunit |
| M. abscessus ATCC 19977 | MAB_1255c | - | 1e-171 | 77.02% (396) | exodeoxyribonuclease VII large subunit XseA |
| M. marinum M | MMAR_4357 | xseA | 0.0 | 79.65% (398) | exodeoxyribonuclease VII (large subunit) XseA |
| M. avium 104 | MAV_1228 | xseA | 1e-173 | 79.74% (380) | exodeoxyribonuclease VII large subunit |
| M. thermoresistible (build 8) | TH_1548 | recN | 2e-05 | 25.68% (183) | PROBABLE DNA REPAIR PROTEIN RECN (RECOMBINATION PROTEIN N) |
| M. ulcerans Agy99 | MUL_0170 | xseA | 1e-179 | 78.89% (398) | exodeoxyribonuclease VII large subunit |
| M. vanbaalenii PYR-1 | Mvan_4633 | xseA | 0.0 | 79.80% (396) | exodeoxyribonuclease VII large subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2077|M.gilvum_PYR-GCK -------MTSARADGTPGQSADNPFPVRGVAIRVAGWIDKLGAVWVEG-Q
Mvan_4633|M.vanbaalenii_PYR-1 -------MTSA-----QGHSPENPFPVRGVAIRVAGWIDKLGAVWVEG-Q
MSMEG_5226|M.smegmatis_MC2_155 --------------------------MRAVATRVAKWIDRLGVVWVEG-Q
Mb1138c|M.bovis_AF2122/97 ---------------MTQNSAENPFPVRAVAIRVAGWIDKLGAVWVEG-Q
Rv1108c|M.tuberculosis_H37Rv ---------------MTQNSAENPFPVRAVAIRVAGWIDKLGAVWVEG-Q
MLBr_01940|M.leprae_Br4923 MTEAVPTDSVDSKASSQVNSAENPFPVRAVALRIAGWIDKLGTVWVEG-Q
MAV_1228|M.avium_104 ---------------------------------------------MEG-Q
MMAR_4357|M.marinum_M -----------MSPAAASNSAENPFPVRAVAIRVAGWIDRLGTVWVEG-Q
MUL_0170|M.ulcerans_Agy99 -----------MSPAAASNSAENPFPVRAVAIRVAGWIDRLGTVWVEG-Q
MAB_1255c|M.abscessus_ATCC_199 -------------MADPGTSPENPWPVRAVATRVAKWIDRLGQVWVEG-Q
TH_1548|M.thermoresistible__bu -VLSEIRIESLGAISSATAEFDRGLTVLTGETGTGKTMVVTGLHLLGGGR
: * :
Mflv_2077|M.gilvum_PYR-GCK IAQLTLRPNSNTAFITLRDPAADMSLSLTCPRDLVVNAPVKMSDGTQVIV
Mvan_4633|M.vanbaalenii_PYR-1 IAQLTLRPNSSTAFITLRDPAADMSLSLTCPRDLVVNAPVKMTDGTQVIV
MSMEG_5226|M.smegmatis_MC2_155 LTELKIRPDSKTVFMVLRDPAADMSLTLTCPRDLVRNAPVRLTEGTQVII
Mb1138c|M.bovis_AF2122/97 LAQITMRPDAKTVFMVLRDPAADMSLTVTCSRDLVLSAPVKLAEGVQVVV
Rv1108c|M.tuberculosis_H37Rv LAQITMRPDAKTVFMVLRDPAADMSLTVTCSRDLVLSAPVKLAEGVQVVV
MLBr_01940|M.leprae_Br4923 LAQITMRPNAKTVFMVLRDPAADISLIVTCSRDFVLRAPVKLAEGIQVVV
MAV_1228|M.avium_104 LAQVSLRPDSKTVFMVLRDPAADMSLTVTCPRDLVLNAPVKLAEGTQVVV
MMAR_4357|M.marinum_M LAQITIRPNSKTVFMVLRDPAADMSLTVTCPRDLVLSAPVKLTEGTQVVV
MUL_0170|M.ulcerans_Agy99 LAQITIRPNSKTVFMVLRDPAADMSLTVTCPRDLVLSAPVKLTEGTQVVV
MAB_1255c|M.abscessus_ATCC_199 LTQIDVRPGSRTVFMVLRDPAADMSLTVTCPPDMVRNAPVKLTEGTQVVV
TH_1548|M.thermoresistible__bu ADPTRVRSGAQRAVVEGRFSTAELLDEAAARVDDILAASGAERDEDGTVI
:*..: ..: * .:*:: :. * : *. : .::
Mflv_2077|M.gilvum_PYR-GCK YGKPSFYTGRGTFSLRVSEIRAVGIGELLARIERLRRLLDAEGLFDPRLK
Mvan_4633|M.vanbaalenii_PYR-1 YGKPNFYTGRGTFSLRVSEIRAVGIGELLARIERLRRLLDTEGLFDPRLK
MSMEG_5226|M.smegmatis_MC2_155 CGKPNFYTGRGTFSLRVSEIRAVGIGELLARIERLRRLLDAEGLFDPRLK
Mb1138c|M.bovis_AF2122/97 CGKPSFYTGRGTFSLRLSEIRAVGIGELLARIDRLRRLLDAEGLFDPRLK
Rv1108c|M.tuberculosis_H37Rv CGKPSFYTGRGTFSLRLSEIRAVGIGELLARIDRLRRLLDAEGLFDPRLK
MLBr_01940|M.leprae_Br4923 CGKPSFYIGRGTFSLRLSDIRAVGIGELLVRIDRLRRLLDSEGLFDPRLK
MAV_1228|M.avium_104 CGKPSFYTGRGTFSLRLSEIRAVGVGELLARIERLRRLLDAEGLFDPRLK
MMAR_4357|M.marinum_M CGKPSFYTGRGTFSLRLNEIRAVGVGELLARIERLRRLLDAEGLFDPRLK
MUL_0170|M.ulcerans_Agy99 CGKPSFYTGRGTFSLRLNEIRAVGVGELLARIERLRRLLDAEGLFDPRLK
MAB_1255c|M.abscessus_ATCC_199 CGKPTFYTGRGSFSLRLSEIRAVGIGELLARIERLRQLLAAEGLFDARLK
TH_1548|M.thermoresistible__bu AARTVSRDGPSRAYLGGRSVPAKSLGNFTGELLTVHGQNDQLRLMRPDEQ
.:. * . * .: * .:*:: .: :: *: . :
Mflv_2077|M.gilvum_PYR-GCK RPIPFLPDTIG-------------LITGRASAAEHDIVAVASGRWPAVRF
Mvan_4633|M.vanbaalenii_PYR-1 RPIPFLPGTIG-------------LITGRASAAEHDIVAVATGRWPAVRF
MSMEG_5226|M.smegmatis_MC2_155 RSIPFLPNTIG-------------LITGRASAAERDVTTVASSRWPAVRF
Mb1138c|M.bovis_AF2122/97 RPIPYLPNMIG-------------LITGRASAAERDVTTVASARWPAARF
Rv1108c|M.tuberculosis_H37Rv RPIPYLPNMIG-------------LITGRASAAERDVTTVASARWPAARF
MLBr_01940|M.leprae_Br4923 RPIPFLPNMIG-------------IITGRASAAERDVTTVASARWPAARF
MAV_1228|M.avium_104 RPIPFLPNMIG-------------LITGRASAAERDVKTVAAGRWPAVRF
MMAR_4357|M.marinum_M RPIPFLPNTVG-------------LITGRASAAERDVTTVAATRWPAVRF
MUL_0170|M.ulcerans_Agy99 RPIPFLPNTVG-------------LITGRASAAERDVTTAAATRWPAVRF
MAB_1255c|M.abscessus_ATCC_199 RPVPFLPARIG-------------LITGRASAAEHDVTSVATTRWPAVQF
TH_1548|M.thermoresistible__bu RAALDRFADLGGRLQRYQLLHQQWLDARRDLADRRERARELAQEADRLTF
*. :* : : * * .:: : . *
Mflv_2077|M.gilvum_PYR-GCK AVRHTVVQGP-----NAVPQIVDALRALDADPDVDVIVLARGGGSVEDLL
Mvan_4633|M.vanbaalenii_PYR-1 AVRNTVVQGP-----NAVPQIVDALRDLDADPDVDVIVLARGGGSVEDLL
MSMEG_5226|M.smegmatis_MC2_155 AIRNTIVQGP-----NAVPQIVDALAALDADPEVDVIVLARGGGSVEDLL
Mb1138c|M.bovis_AF2122/97 AVRNVAVQGP-----NAVGQIVEALRELDRDPDVDVIVLARGGGSVEDLL
Rv1108c|M.tuberculosis_H37Rv AVRNVAVQGP-----NAVGQIVEALRELDRDPDVDVIVLARGGGSVEDLL
MLBr_01940|M.leprae_Br4923 AIRNTAVQGP-----NAVSQIVEALRELDRNVDVEVIVVARGGGSVEDLL
MAV_1228|M.avium_104 AVRNTAVQGP-----NAVAQIVEALRELDRDPEVDVIVLARGGGSVEDLL
MMAR_4357|M.marinum_M AVRNTAVQGP-----NAVAQIVEALRELDSDLEVDVIVVARGGGSVEDLL
MUL_0170|M.ulcerans_Agy99 AVRNTAVQGP-----NAVAQIVEALRELDSDLEVDVIVVARGGGSVEDLL
MAB_1255c|M.abscessus_ATCC_199 AIRNTPVQGP-----HAVAEIVAALQALDADPSVDVIVLARGGGSVEDLL
TH_1548|M.thermoresistible__bu ALNEIDAVAPQPGEDDALAENIRRLSELDALREAARTARARLSGALDDDA
*:.. . .* .*: : : * ** .. . ** .*:::*
Mflv_2077|M.gilvum_PYR-GCK PFSDETLCREIARCTTPVVS-------AIGHEPDNP------LCDLVADL
Mvan_4633|M.vanbaalenii_PYR-1 PFSDETLCREIAACTTPVVS-------AIGHEPDNP------LCDLVADL
MSMEG_5226|M.smegmatis_MC2_155 PFSDETLCRAISACRTPVVS-------AIGHEPDNP------VCDLVADL
Mb1138c|M.bovis_AF2122/97 PFSDETLCRAIAACRTPVVS-------AVGHEPDNP------LCDLVVDL
Rv1108c|M.tuberculosis_H37Rv PFSDETLCRAIAACRTPVVS-------AVGHEPDNP------LCDLVVDL
MLBr_01940|M.leprae_Br4923 TFSDETLCRAIAACRTPVIS-------AVGHEPDNP------LCDLVADL
MAV_1228|M.avium_104 PFSDETLCRAIAACRTPVIS-------AVGHEPDNP------LCDLVADV
MMAR_4357|M.marinum_M PFSDETLCRAIAACRTPVIS-------AVGHEPDNP------LCDLVADL
MUL_0170|M.ulcerans_Agy99 LFSDETLCRAIAACRTPVIS-------AVGHEPDNP------LCDLVADL
MAB_1255c|M.abscessus_ATCC_199 PFSDETLCRAISACRTPVVS-------AVGHEPDNP------LSDLVADL
TH_1548|M.thermoresistible__bu AVDATSALDQVGQAKAALESTDDTALRALGARLDEALLLIGDVADELGGY
.. : :. . :.: * *:* . *:. :.* : .
Mflv_2077|M.gilvum_PYR-GCK RAATPTDAAKRIVPDTAAEQALITDLRRRSARALRNWVNRETHVVTQLRS
Mvan_4633|M.vanbaalenii_PYR-1 RAATPTDAAKRIVPDTAAEQALVTDLRRRSARALRNWVNREAHTVAQLRS
MSMEG_5226|M.smegmatis_MC2_155 RAATPTDAAKRIVPDAAAEQALISDLHRRSARALRNWVHREQHHLDQLRS
Mb1138c|M.bovis_AF2122/97 RAATPTDAAKKVVPDTAAEQRLIDDLRRRSAQALRNWVSREQRAVAQLRS
Rv1108c|M.tuberculosis_H37Rv RAATPTDAAKKVVPDTAAEQRLIDDLRRRSAQALRNWVSREQRAVAQLRS
MLBr_01940|M.leprae_Br4923 RAATPTDAAKKVVPDAAVEQRLIEDLQRRSAQALRNWVSREQRTLVQLRS
MAV_1228|M.avium_104 RAATPTDAAKKVVPDTAAEQRLIDDLRRRSAQALRNWVSREQRALAQIRS
MMAR_4357|M.marinum_M RAATPTDAAKKAVPDTAAEQRLVADLRRRSAQALRNWVSREQRALTQLRS
MUL_0170|M.ulcerans_Agy99 RAATPTDAAKKAVPDTAAEQRLVADLRRRSAQALRNWVSREQRALTQLRS
MAB_1255c|M.abscessus_ATCC_199 RAATPTDAAKKLVPDAAAEQALILDLRRRSAQALRNWVQREQRGLDQVRS
TH_1548|M.thermoresistible__bu LEGLPTDAS--TLETSLARQSELRTLTRKYAADIDGVLQWAQQARDRLAQ
. ****: : : ..* : * *: * : . : : :: .
Mflv_2077|M.gilvum_PYR-GCK RPVMSRPLAAIDARSDEIHRARAAVRRDITRLVGIESD------------
Mvan_4633|M.vanbaalenii_PYR-1 RPVLARPLAAIDARAEEIHRARAAARRDVKRLLATEAD------------
MSMEG_5226|M.smegmatis_MC2_155 RPVLAQPLAAITARGDEIHRARATAQRDITRLIAGETD------------
Mb1138c|M.bovis_AF2122/97 RPVLADPMTMVSVRAEEVHRARSTLRRNLTLMVAAETE------------
Rv1108c|M.tuberculosis_H37Rv RPVLADPMTMVSVRAEEVHRARSTLRRNLTLMVAAETE------------
MLBr_01940|M.leprae_Br4923 RPVLAEPLRTLTTRSEEIHRAQSAIRREIIRLVTTETE------------
MAV_1228|M.avium_104 RPVLAEPLRALTARAEEVHRARSAIRRDVTRLTAAETE------------
MMAR_4357|M.marinum_M RPVLADPLKALITRSDEIQRARSALRRDVSRLISTETE------------
MUL_0170|M.ulcerans_Agy99 HPVLADPLKALITRSDEIQRARSALRRDVSRLISTETE------------
MAB_1255c|M.abscessus_ATCC_199 RPVLADPLRMVSVRQDEIDGARNALRRDVRRLVDIESQ------------
TH_1548|M.thermoresistible__bu LDVSEEALGELERRVDELQAQVVSAAMDLTKARTRAAGRLAKAVTAELAG
* .: : * :*:. : :: :
Mflv_2077|M.gilvum_PYR-GCK ----------RIGHLSARLTTLGPAATLARGYAVVQTIPESG--------
Mvan_4633|M.vanbaalenii_PYR-1 ----------RVGHLTARLTTLGPAATLARGYAVVQTIATSG--------
MSMEG_5226|M.smegmatis_MC2_155 ----------TIGHLSARLTALGPAATLARGYAVVQAVPDTG--------
Mb1138c|M.bovis_AF2122/97 ----------RIGHLAARLATLGPAATLARGYAIVQTVAQTGPEG----G
Rv1108c|M.tuberculosis_H37Rv ----------RIGHLAARLATLGPAATLARGYAIVQTVAQTGPEG----G
MLBr_01940|M.leprae_Br4923 ----------RVGHLATQLATLGPAATLARGYAIVQALEDG--TQ----T
MAV_1228|M.avium_104 ----------RIGHLRARLATLGPAATLARGYAVVQTVGAGG--------
MMAR_4357|M.marinum_M ----------NIGHLGARLATLGPAATLARGYAVVQTVSTAG--------
MUL_0170|M.ulcerans_Agy99 ----------NIGHLGARLATLGPAATLARGYAVVQTVSTAG--------
MAB_1255c|M.abscessus_ATCC_199 ----------RVEHLTARLTTLGPAATLARGYSVVQRVRDDG--------
TH_1548|M.thermoresistible__bu LAMADAEFTVTVGPLTARPDDTAPLTMPDGQTVHAGRHGVDGVEFGFTAH
: * :: .* : .
Mflv_2077|M.gilvum_PYR-GCK -EPRILGSVDDAPAGTRLRVRVADGAITATSEGGQ---------------
Mvan_4633|M.vanbaalenii_PYR-1 -EPHVLHSVSDAPAGARLRIRVTDGAVTAISEGSE---------------
MSMEG_5226|M.smegmatis_MC2_155 -PPTVLRSTDDAPAGTRLRVRVSDGVVTARSEGTEDDETGSST-------
Mb1138c|M.bovis_AF2122/97 SEPQVLRSVHDAPEGTKLRVRVADGALAAVSEGQTNGL------------
Rv1108c|M.tuberculosis_H37Rv SEPQVLRSVHDAPEGTKLRVRVADGALAAVSEGQTNGL------------
MLBr_01940|M.leprae_Br4923 VTAAVLRSVDDAPTGTRLRVRVSDGAIVAVSEGRADGP------------
MAV_1228|M.avium_104 --PHVLRTVGDAPAGTRLRVRVADGAVAALSEGPTDGE------------
MMAR_4357|M.marinum_M QPMEVLRSVDGAPAGTRLRVRVGDGAVTAVSEGRVDGA------------
MUL_0170|M.ulcerans_Agy99 QPMEVLRSVDGAPAGTRLRVRVGDGAVTAVSEGRVDGA------------
MAB_1255c|M.abscessus_ATCC_199 -TVEVLRTVADAPVGAPLRVRVSDGAVTATVTGEDS--------------
TH_1548|M.thermoresistible__bu RGTDVLPLAKSASGGELSRVMLALEVVLAASAEGTTMVFDEVDAGVGGRA
:* . .*. * *: : .: *
Mflv_2077|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4633|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5226|M.smegmatis_MC2_155 --------------------------------------------------
Mb1138c|M.bovis_AF2122/97 --------------------------------------------------
Rv1108c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01940|M.leprae_Br4923 --------------------------------------------------
MAV_1228|M.avium_104 --------------------------------------------------
MMAR_4357|M.marinum_M --------------------------------------------------
MUL_0170|M.ulcerans_Agy99 --------------------------------------------------
MAB_1255c|M.abscessus_ATCC_199 --------------------------------------------------
TH_1548|M.thermoresistible__bu AVQIGRRLARLARTHQVIVVTHLPQVAAYADIHLVVDSGGRDADNRGASR
Mflv_2077|M.gilvum_PYR-GCK ----------------------------------------------
Mvan_4633|M.vanbaalenii_PYR-1 ----------------------------------------------
MSMEG_5226|M.smegmatis_MC2_155 ----------------------------------------------
Mb1138c|M.bovis_AF2122/97 ----------------------------------------------
Rv1108c|M.tuberculosis_H37Rv ----------------------------------------------
MLBr_01940|M.leprae_Br4923 ----------------------------------------------
MAV_1228|M.avium_104 ----------------------------------------------
MMAR_4357|M.marinum_M ----------------------------------------------
MUL_0170|M.ulcerans_Agy99 ----------------------------------------------
MAB_1255c|M.abscessus_ATCC_199 ----------------------------------------------
TH_1548|M.thermoresistible__bu VQRLDEEGRVAELARMLAGLGETDSGRAHARELLEAAQRERAEVSV