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TAPNDPPSGPRPSEPAAEPSPPSDTRTRIIRRAPTGPIPVTPDSPTTHFAPQPPSYRGGPRAGRTGYSGL PALEPSDRTAVAACAVAIVSGWATSVVATDLIAGWWRSDRLFCIAVGFLALVFAATTVSGVIGLLQRRSV SRYLLLAGALVAFLTYIGVFIAGARVAWVVHLLPVLPIATVVLVLLPQTKRWLDA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1072 | - | - | 100% (196) | hypothetical protein MAV_1072 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3906 | - | 6e-05 | 32.43% (74) | hypothetical protein Mb3906 |
| M. gilvum PYR-GCK | Mflv_1863 | - | 2e-38 | 44.17% (206) | hypothetical protein Mflv_1863 |
| M. tuberculosis H37Rv | Rv3876 | - | 6e-05 | 32.43% (74) | hypothetical protein Rv3876 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1963 | - | 2e-05 | 34.44% (90) | MmpS family protein |
| M. marinum M | MMAR_4552 | - | 1e-50 | 66.67% (156) | hypothetical protein MMAR_4552 |
| M. smegmatis MC2 155 | MSMEG_5527 | - | 6e-42 | 43.56% (202) | hypothetical protein MSMEG_5527 |
| M. thermoresistible (build 8) | TH_2201 | - | 2e-30 | 51.38% (109) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4722 | - | 8e-61 | 63.96% (197) | hypothetical protein MUL_4722 |
| M. vanbaalenii PYR-1 | Mvan_4872 | - | 2e-38 | 45.56% (180) | hypothetical protein Mvan_4872 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4552|M.marinum_M --------------------------------------------------
MUL_4722|M.ulcerans_Agy99 --------------------------------------------------
MAV_1072|M.avium_104 --------------------------------------------------
MSMEG_5527|M.smegmatis_MC2_155 --------------------------------------------------
TH_2201|M.thermoresistible__bu --------------------------------------------------
Mflv_1863|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4872|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 MAADYDKLFRPHEGMEAPDDMAAQPFFDPSASFPPAPASANLPKPNGQTP
Rv3876|M.tuberculosis_H37Rv MAADYDKLFRPHEGMEAPDDMAAQPFFDPSASFPPAPASANLPKPNGQTP
MAB_1963|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4552|M.marinum_M --------------------------------------------------
MUL_4722|M.ulcerans_Agy99 --------------------------------------------------
MAV_1072|M.avium_104 --------------------------------------------------
MSMEG_5527|M.smegmatis_MC2_155 --------------------------------------------------
TH_2201|M.thermoresistible__bu --------------------------------------------------
Mflv_1863|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4872|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 PPTSDDLSERFVSAPPPPPPPPPPPPPTPMPIAAGEPPSPEPAASKPPTP
Rv3876|M.tuberculosis_H37Rv PPTSDDLSERFVSAPPPPPPPPPPPPPTPMPIAAGEPPSPEPAASKPPTP
MAB_1963|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4552|M.marinum_M --------------------------------------------------
MUL_4722|M.ulcerans_Agy99 --------------------------------------------------
MAV_1072|M.avium_104 --------------------------------------------------
MSMEG_5527|M.smegmatis_MC2_155 --------------------------------------------------
TH_2201|M.thermoresistible__bu --------------------------------------------------
Mflv_1863|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4872|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 PMPIAGPEPAPPKPPTPPMPIAGPEPAPPKPPTPPMPIAGPAPTPTESQL
Rv3876|M.tuberculosis_H37Rv PMPIAGPEPAPPKPPTPPMPIAGPEPAPPKPPTPPMPIAGPAPTPTESQL
MAB_1963|M.abscessus_ATCC_1997 ---MSGTDNPGSGNPGEVPDLDGPNEEAAAPDSS----------------
MMAR_4552|M.marinum_M --------------------------------------------------
MUL_4722|M.ulcerans_Agy99 -----------------------------------------MTAPGDPAA
MAV_1072|M.avium_104 -----------------------------------------MTAPNDPPS
MSMEG_5527|M.smegmatis_MC2_155 -----------------------------------------MSDSGPLDT
TH_2201|M.thermoresistible__bu --------------------------------------------------
Mflv_1863|M.gilvum_PYR-GCK -----------------------------------------MASDPPSTS
Mvan_4872|M.vanbaalenii_PYR-1 -----------------------------------------MADES----
Mb3906|M.bovis_AF2122/97 APPRPPTPQTPTGAPQQPESPAPHVPSHGPHQPRRTAPAPPWAKMPIGEP
Rv3876|M.tuberculosis_H37Rv APPRPPTPQTPTGAPQQPESPAPHVPSHGPHQPRRTAPAPPWAKMPIGEP
MAB_1963|M.abscessus_ATCC_1997 GADSAAFHSQAYSAPESEQFTSPYVP-----------YDEYETQLVDGEE
MMAR_4552|M.marinum_M -------------------------------------------MTTDSAT
MUL_4722|M.ulcerans_Agy99 SETP----LDPSPSADEP---RTRIIRR---APTGP-----QPVTTDSAT
MAV_1072|M.avium_104 GPRP----SEPAAEPSPPSDTRTRIIRR---APTGP-----IPVTPDSPT
MSMEG_5527|M.smegmatis_MC2_155 --------------DQSGEDDRTRIIRRQPSSPLSGPVPTSDPLSDDVPK
TH_2201|M.thermoresistible__bu --------------------------------------------------
Mflv_1863|M.gilvum_PYR-GCK STAPEPGEPAQVPPSDRDEDTSTRIIRR---APLNTGMNTGSRAAAAEPQ
Mvan_4872|M.vanbaalenii_PYR-1 --------------SDSTEET--RILRR---APLNTGAAP--SAPTSEPV
Mb3906|M.bovis_AF2122/97 PPAPSRPSASPAEPPTRPAPQHSRRARRGHRYRTDTERNVGKVATGPSIQ
Rv3876|M.tuberculosis_H37Rv PPAPSRPSASPAEPPTRPAPQHSRRARRGHRYRTDTERNVGKVATGPSIQ
MAB_1963|M.abscessus_ATCC_1997 PPPPRWPWVVGVAAIIAAITLVASVALLVAGRSDETNGAAKSSTVIPTPS
MMAR_4552|M.marinum_M AKISHRPT-----------------------SLDETARADRLPPLPDGLP
MUL_4722|M.ulcerans_Agy99 AKISHRPT-----------------------SLDETARADRLPPLPDGLP
MAV_1072|M.avium_104 THFAPQPP-----------------------SYRGGPRAGRTG--YSGLP
MSMEG_5527|M.smegmatis_MC2_155 TSIIRRHPTGAIPTAPDAEPQTSLIGAQSDASGPEDAGEAATAYVPRARP
TH_2201|M.thermoresistible__bu --------------------------------------------------
Mflv_1863|M.gilvum_PYR-GCK TTILRRHPTGALPAL----------------SEPVTQAVRHPEPVPGPPP
Mvan_4872|M.vanbaalenii_PYR-1 TQIVPR-------------------------AQPVAVGP------PRAAR
Mb3906|M.bovis_AF2122/97 ARLRAEEASGAQLAPGTEPSPAPLGQPRSYLAPPTRPAPTEPPPSPSPQR
Rv3876|M.tuberculosis_H37Rv ARLRAEEASGAQLAPGTEPSPAPLGQPRSYLAPPTRPAPTEPPPSPSPQR
MAB_1963|M.abscessus_ATCC_1997 TTPWNEIITTTTPPP----------------PPPPPPPTTEPPPPPPPPV
MMAR_4552|M.marinum_M --------------------------------------------------
MUL_4722|M.ulcerans_Agy99 --------------------------------------------------
MAV_1072|M.avium_104 A-------------------------------------------------
MSMEG_5527|M.smegmatis_MC2_155 LV------------------------------------------------
TH_2201|M.thermoresistible__bu --------------------------------------------------
Mflv_1863|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4872|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 NSGRRAERRVHPDLAAQHAAAQPDSITAATTGGRRRKRAAPDLDATQKSL
Rv3876|M.tuberculosis_H37Rv NSGRRAERRVHPDLAAQHAAAQPDSITAATTGGRRRKRAAPDLDATQKSL
MAB_1963|M.abscessus_ATCC_1997 VT------------------------------------------------
MMAR_4552|M.marinum_M -----------VEPSSRTAVATAAVSIVNGWATSVVATDLITGWWRSDR-
MUL_4722|M.ulcerans_Agy99 -----------VEPSSRTAVATAAVSIVNGWATSVVATDLITGWWRSGR-
MAV_1072|M.avium_104 -----------LEPSDRTAVAACAVAIVSGWATSVVATDLIAGWWRSDR-
MSMEG_5527|M.smegmatis_MC2_155 ------IPRRASANDPKTAVTAATLSILSGWGTAVIATDLIAGWWRTDQ-
TH_2201|M.thermoresistible__bu -----------------------VVTILSGWATAVIATDLITGWWRTDR-
Mflv_1863|M.gilvum_PYR-GCK -------------ADPTSAIATTVASIVAGWATGVIATDLITGWWATDP-
Mvan_4872|M.vanbaalenii_PYR-1 -------------ADPKSAIATAVTSILSGWATTVIATDLITGWWATDP-
Mb3906|M.bovis_AF2122/97 RPAAKGPKVKKVKPQKPKATKPPKVVSQRGWRHWVHALTRINLGLSPDEK
Rv3876|M.tuberculosis_H37Rv RPAAKGPKVKKVKPQKPKATKPPKVVSQRGWRHWVHALTRINLGLSPDEK
MAB_1963|M.abscessus_ATCC_1997 ----------ETVTVEPPPPPPPPVTTHEAPPPVTTTTTPPPPPPPTTT-
. . : .
MMAR_4552|M.marinum_M ----------------LFCIAVGFLALVFASSTTAGVIMLLLRRPFGRYL
MUL_4722|M.ulcerans_Agy99 ----------------LFCIAVGFLALVFASSTTAGVIMLLLRRPFGRYL
MAV_1072|M.avium_104 ----------------LFCIAVGFLALVFAATTVSGVIGLLQRRSVSRYL
MSMEG_5527|M.smegmatis_MC2_155 ----------------LFCVAVGFLTAVSAAATIGGLIALLLRRRLGRLL
TH_2201|M.thermoresistible__bu ----------------LFCVAVGFLTAVSAAAMIGGLILMLLRRRLGRLL
Mflv_1863|M.gilvum_PYR-GCK ----------------LFCVAMGFLAAVSAAASISGVIALLLRRRTARLL
Mvan_4872|M.vanbaalenii_PYR-1 ----------------LFCVAMGFLAAVSAAASISGLIALLLRRRTARLL
Mb3906|M.bovis_AF2122/97 YELDLHARVRRNPRGSYQIAVVGLKGGAGKTTLTAALGSTLAQVRADRIL
Rv3876|M.tuberculosis_H37Rv YELDLHARVRRNPRGSYQIAVVGLKGGAGKTTLTAALGSTLAQVRADRIL
MAB_1963|M.abscessus_ATCC_1997 ----------------TPAGPRQITYSVTGSKAPLDRISITWTDGSGRTR
: . : *
MMAR_4552|M.marinum_M IVVG----------------------------------------------
MUL_4722|M.ulcerans_Agy99 IVVG----------------------------------------------
MAV_1072|M.avium_104 LLAG----------------------------------------------
MSMEG_5527|M.smegmatis_MC2_155 IVVG----------------------------------------------
TH_2201|M.thermoresistible__bu TVVG----------------------------------------------
Mflv_1863|M.gilvum_PYR-GCK IVVG----------------------------------------------
Mvan_4872|M.vanbaalenii_PYR-1 VVVG----------------------------------------------
Mb3906|M.bovis_AF2122/97 ALDADPGAGNLADRVGRQSGATIADVLAEKELSHYNDIRAHTSVNAVNLE
Rv3876|M.tuberculosis_H37Rv ALDADPGAGNLADRVGRQSGATIADVLAEKELSHYNDIRAHTSVNAVNLE
MAB_1963|M.abscessus_ATCC_1997 VNPN----------------------------------------------
MMAR_4552|M.marinum_M --------------------------------------------------
MUL_4722|M.ulcerans_Agy99 --------------------------------------------------
MAV_1072|M.avium_104 --------------------------------------------------
MSMEG_5527|M.smegmatis_MC2_155 --------------------------------------------------
TH_2201|M.thermoresistible__bu --------------------------------------------------
Mflv_1863|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4872|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 VLPAPEYSSAQRALSDADWHFIADPASRFYNLVLADCGAGFFDPLTRGVL
Rv3876|M.tuberculosis_H37Rv VLPAPEYSSAQRALSDADWHFIADPASRFYNLVLADCGAGFFDPLTRGVL
MAB_1963|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4552|M.marinum_M -AVVAVLTYGGVFIAGARVAWIVHAFP--------VLPIASAVLALHPQT
MUL_4722|M.ulcerans_Agy99 -AVVAVLTYGGVFIAGALVAWIVHAFP--------VLPIASAVLALHPQT
MAV_1072|M.avium_104 -ALVAFLTYIGVFIAGARVAWVVHLLP--------VLPIATVVLVLLPQT
MSMEG_5527|M.smegmatis_MC2_155 -AVIALLIFGSLFIAGAKLHPLVYAIP--------VLPVSAILFAVLPAT
TH_2201|M.thermoresistible__bu -GVIGLLIFGSLFVAGAALPPVVYAIP--------ILPVTSIVLTVLPAT
Mflv_1863|M.gilvum_PYR-GCK -AVIALLIFAGLFVAGAALPGPVYALP--------LLPAAAIALAALPGT
Mvan_4872|M.vanbaalenii_PYR-1 -AVIALLIFASLFVAGANLPALVYAMP--------LLPAASIVLAALPAT
Mb3906|M.bovis_AF2122/97 STVSGVVVVASVSIDGAQQASVALDWLRNNGYQDLASRACVVINHIMPGE
Rv3876|M.tuberculosis_H37Rv STVSGVVVVASVSIDGAQQASVALDWLRNNGYQDLASRACVVINHIMPGE
MAB_1963|M.abscessus_ATCC_1997 --VYIPWSITVTPISNSEIGSVSASSF---------LRLSQLNCTITTSD
: : .: .
MMAR_4552|M.marinum_M RRWLFD--------------------------------------------
MUL_4722|M.ulcerans_Agy99 RRWLFD--------------------------------------------
MAV_1072|M.avium_104 KRWLDA--------------------------------------------
MSMEG_5527|M.smegmatis_MC2_155 GRWAVRSE------------------------------------------
TH_2201|M.thermoresistible__bu GRWADLS-------------------------------------------
Mflv_1863|M.gilvum_PYR-GCK ARWSRAD-------------------------------------------
Mvan_4872|M.vanbaalenii_PYR-1 ARWSRSA-------------------------------------------
Mb3906|M.bovis_AF2122/97 PNVAVKDLVRHFEQQVQPGRVVVMPWDRHIAAGTEISLDLLDPIYKRKVL
Rv3876|M.tuberculosis_H37Rv PNVAVKDLVRHFEQQVQPGRVVVMPWDRHIAAGTEISLDLLDPIYKRKVL
MAB_1963|M.abscessus_ATCC_1997 GQVLSSNNNNSAQATC----------------------------------
.
MMAR_4552|M.marinum_M ----------------
MUL_4722|M.ulcerans_Agy99 ----------------
MAV_1072|M.avium_104 ----------------
MSMEG_5527|M.smegmatis_MC2_155 ----------------
TH_2201|M.thermoresistible__bu ----------------
Mflv_1863|M.gilvum_PYR-GCK ----------------
Mvan_4872|M.vanbaalenii_PYR-1 ----------------
Mb3906|M.bovis_AF2122/97 ELAAALSDDFERAGRR
Rv3876|M.tuberculosis_H37Rv ELAAALSDDFERAGRR
MAB_1963|M.abscessus_ATCC_1997 ----------------