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MTTGASNIRHGDRGPAVTEVREVLTALGFLEDPDEVLATGRHVMVDRFDATLDDAVRAFQQCRGLLVDGI VGPATYRTLKEASYRLGARTLFHQFSAPMYGDDVATLQKRLQDLGFYTGLVDGNFGLQTYNSLMSYQREY GLTADGICGPETLRSFQLLGRHVTGGSAHAIRETEHVRNAGPQLSGKRIVIDPGLGGGDRGRIVPGREGP TSEADILWDLASRLEGRMTAIGMDTYISRAIQNNPTDVERATYANNVGADLMISLRFDAQPTVAASGVAS YHFGNLHGSVSTIGHMLADFIQREVAARTGLRDCRAHGRTWDLLRLTRMPTVQVDIGYITSPHDVSILSS AHYRDVVAESILAAVKRVYLLGKNDRPTGTFTFDELLAHELSAGS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4942 | - | - | 100% (395) | N-acetylmuramoyl-L-alanine amidase CwlM |
| M. abscessus ATCC 19977 | MAB_0318c | - | 3e-06 | 23.58% (229) | hypothetical protein MAB_0318c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3946 | - | 1e-165 | 75.06% (385) | putative hydrolase |
| M. gilvum PYR-GCK | Mflv_0837 | - | 1e-164 | 74.68% (387) | peptidoglycan binding domain-containing protein |
| M. tuberculosis H37Rv | Rv3915 | - | 1e-165 | 75.06% (385) | hydrolase |
| M. leprae Br4923 | MLBr_02704 | - | 1e-160 | 71.43% (385) | putative hydrolase |
| M. marinum M | MMAR_5479 | - | 1e-165 | 74.29% (385) | hydrolase |
| M. avium 104 | MAV_5303 | - | 1e-167 | 75.32% (385) | putative N-acetylmuramoyl-L-alanine amidase |
| M. smegmatis MC2 155 | MSMEG_6935 | - | 1e-165 | 75.45% (387) | N-acetylmuramoyl-L-alanine amidase |
| M. thermoresistible (build 8) | TH_2411 | - | 1e-164 | 73.90% (387) | PROBABLE HYDROLASE |
| M. ulcerans Agy99 | MUL_5068 | - | 1e-164 | 74.03% (385) | hydrolase |
| M. vanbaalenii PYR-1 | Mvan_6069 | - | 1e-164 | 74.68% (387) | peptidoglycan binding domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_5479|M.marinum_M MPSPRREDGDTLRCGDRSAAVAEIRAALAALGMLDNPDEDLSTGRHIALE
MUL_5068|M.ulcerans_Agy99 MPSPRREDGDTLRCGDRSAAVAEIRAALAALGMLDNPDEDLSTGRHIALE
Mb3946|M.bovis_AF2122/97 MPSPRREDGDALRCGDRSAAVTEIRAALTALGMLDHQEEDLTTGRNVALE
Rv3915|M.tuberculosis_H37Rv MPSPRREDGDALRCGDRSAAVTEIRAALTALGMLDHQEEDLTTGRNVALE
MLBr_02704|M.leprae_Br4923 MSSPRCEDGDTLRCGDRNAAVTEIRSALAALGLLHSPGDDLTTSKYIALD
MAV_5303|M.avium_104 MSSPRREYGDALRCGDRSAAVTEIRATLASLGLLASADEDLSTGRHVALE
Mflv_0837|M.gilvum_PYR-GCK MSS--------LRRGDRGGAVAEIRAALAALGMATDPDEDLSTGKHVAAD
Mvan_6069|M.vanbaalenii_PYR-1 MSS--------LRRGDRGGAVAEIRAALSALGMIDSPDEDLTTGKHVAAD
TH_2411|M.thermoresistible__bu MSS--------LRRGDRGSAVAEIRAALAGLGLIDNPDDDLSTGRHVVPD
MSMEG_6935|M.smegmatis_MC2_155 MSS--------LRRGDRGGAVTEIRAALAALGLIENPDTDLSTGRHVALD
MAB_4942|M.abscessus_ATCC_1997 MTTG----ASNIRHGDRGPAVTEVREVLTALGFLEDPDEVLATGRHVMVD
*.: :* ***. **:*:* .*:.**: *:*.: : :
MMAR_5479|M.marinum_M LFDPELDHAVRAFQQHRGLLVDGIVGEATYRALREASYRLGARTLYHQFG
MUL_5068|M.ulcerans_Agy99 LFDPELDHAVRAFQQHRGLLVDGIVGEATYRALREASYRLGARTLYHQFG
Mb3946|M.bovis_AF2122/97 LFDAQLDQAVRAFQQHRGLLVDGIVGEATYRALKEASYRLGARTLYHQFG
Rv3915|M.tuberculosis_H37Rv LFDAQLDQAVRAFQQHRGLLVDGIVGEATYRALKEASYRLGARTLYHQFG
MLBr_02704|M.leprae_Br4923 LFDPQLEHAVRAFQQHRGLLVDGVVGEATHRALKEASYRLGARTLYHRFG
MAV_5303|M.avium_104 LFDAELDQAVRAFQQHRGLLVDGIVGEATYRALKEASYRLGARTLYHQFG
Mflv_0837|M.gilvum_PYR-GCK LFDDELDHAVRAFQQHRGLLVDGIVGEATYRALKEASYRLGARTLNHQFG
Mvan_6069|M.vanbaalenii_PYR-1 MFDDDLDHAVRAFQQHRGLLVDGIVGEATYRALKEASYRLGARTLNHQFG
TH_2411|M.thermoresistible__bu YFDDELDQAVRAFQQQRGLLVDGVVGEATYRALKEASYRLGARTLSHQFG
MSMEG_6935|M.smegmatis_MC2_155 VFDDELDHAVRAFQQHRGLLVDGIVGEATYRALREASYRLGARILSHQFG
MAB_4942|M.abscessus_ATCC_1997 RFDATLDDAVRAFQQCRGLLVDGIVGPATYRTLKEASYRLGARTLFHQFS
** *:.******* *******:** **:*:*:********* * *:*.
MMAR_5479|M.marinum_M APLYGDDVATLQARLQDLGFYTGLVDGYFGLQTHNALMSYQREYGMSADG
MUL_5068|M.ulcerans_Agy99 APLYGDDVATLQARLQDLGFYTGLVDGYFGLQTHNALMSYQREYGMSADG
Mb3946|M.bovis_AF2122/97 APLYGDDVATLQARLQDLGFYTGLVDGHFGLQTHNALMSYQREYGLAADG
Rv3915|M.tuberculosis_H37Rv APLYGDDVATLQARLQDLGFYTGLVDGHFGLQTHNALMSYQREYGLAADG
MLBr_02704|M.leprae_Br4923 APLSGDDVATLQARLQDLGFYTGMVDGHFGLQTHNALISYQREYGLTADG
MAV_5303|M.avium_104 APLYGDDVATLQARLQDLGFYTGLVDGYFGLQTHNALMSYQREYGLSADG
Mflv_0837|M.gilvum_PYR-GCK APMYGDDVATLQARLQDLGFYTGLVDGHFGLQTHNALSSYQREYGLYPDG
Mvan_6069|M.vanbaalenii_PYR-1 APMYGDDVATLQSRLQDLGFYTGLVDGHFGLQTHNALSSYQREYGLYPDG
TH_2411|M.thermoresistible__bu APMYGDDVATLQLRLQELGFYTGLVDGHFGLQTHNALMSYQREYGLYPDG
MSMEG_6935|M.smegmatis_MC2_155 APMYGDDVATLQARLQDLGFYTGLVDGYFGLQTHNALMSYQREYGLYPDG
MAB_4942|M.abscessus_ATCC_1997 APMYGDDVATLQKRLQDLGFYTGLVDGNFGLQTYNSLMSYQREYGLTADG
**: ******** ***:******:*** *****:*:* *******: .**
MMAR_5479|M.marinum_M ICGPETLRSLYFLSSRVSGGSPHAIREEELVRRSGPKLSGKRIIIDPGRG
MUL_5068|M.ulcerans_Agy99 ICGPETLRSLYFLSSRVSGGSPHAIREEELVRRSGPKLSGKRIIIDPGRG
Mb3946|M.bovis_AF2122/97 ICGPETLRSLYFLSSRVSGGSPHAIREEELVRSSGPKLSGKRIIIDPGRG
Rv3915|M.tuberculosis_H37Rv ICGPETLRSLYFLSSRVSGGSPHAIREEELVRSSGPKLSGKRIIIDPGRG
MLBr_02704|M.leprae_Br4923 ICGPETLRSLYFLSSRVTGGSPHAIREEELVRRSGPKLSGKRIIIDPGRG
MAV_5303|M.avium_104 ICGPETLRSLYFLSSRVTGGSPHALREEELVRRSGPKLSGKRIIIDPGRG
Mflv_0837|M.gilvum_PYR-GCK ICGPETLRSLYFLGARVTGGSPHAIREEELVRSSGPRLSGKRIIVDPGRG
Mvan_6069|M.vanbaalenii_PYR-1 ICGPETLRSLYFLGSRVTGGSPHAIREEELVRRSGPRLSGKRIIIDPGRG
TH_2411|M.thermoresistible__bu ICGPETLRSLYFLGSRVTGGSPHAIREEEMVRRSGPRLSGKRIIIDPGLG
MSMEG_6935|M.smegmatis_MC2_155 ICGPETLRSLYFLGSRVTGGSPHAIREEELVRRSGPRLSGKRVIIDPGRG
MAB_4942|M.abscessus_ATCC_1997 ICGPETLRSFQLLGRHVTGGSAHAIRETEHVRNAGPQLSGKRIVIDPGLG
*********: :*. :*:***.**:** * ** :**:*****:::*** *
MMAR_5479|M.marinum_M GSDRGLIAHGEAGPVSEADVLWDLASRLEGRMSAIGMETFLSRPANTSPS
MUL_5068|M.ulcerans_Agy99 GSDRGVIAHGEAGPISEADVLWDLASRLEGRMSAIGMETFFSRPANTSPS
Mb3946|M.bovis_AF2122/97 GVDHGLIAQGPAGPISEADLLWDLASRLEGRMAAIGMETHLSRPTNRSPS
Rv3915|M.tuberculosis_H37Rv GVDHGLIAQGPAGPISEADLLWDLASRLEGRMAAIGMETHLSRPTNRSPS
MLBr_02704|M.leprae_Br4923 GADRGLITQGPTGPISEADVLWDLASRLEGRMAAIGIETFLSRTTNGSPS
MAV_5303|M.avium_104 GADHGMIMQGPSGPISEADVLWDLASRLEGRMTAIGMETFLSRPVNRSPL
Mflv_0837|M.gilvum_PYR-GCK GSDHGVIVNGPDGPISEADILWDLASRLEGRMTAIGIETFLSRSANSSPT
Mvan_6069|M.vanbaalenii_PYR-1 GSDHGLIMNGPAGPISEADILWDLASRLEGRMTAIGIETFLSRSAHTSAS
TH_2411|M.thermoresistible__bu GSERGLIMSTPRGPISEADILWDLASRLEGRMTAIGMETSLSRSAHHCPT
MSMEG_6935|M.smegmatis_MC2_155 GSDHGLIMQGPHGPISEADILWDLASRLEGRMTAIGMDTVLSRPPNRSPS
MAB_4942|M.abscessus_ATCC_1997 GGDRGRIVPGREGPTSEADILWDLASRLEGRMTAIGMDTYISRAIQNNPT
* ::* * ** ****:************:***::* :**. : .
MMAR_5479|M.marinum_M DAERAATANAVGADLMISLRCETQTTVSANGVASFHFGNSHGSVSTIGRN
MUL_5068|M.ulcerans_Agy99 DAERAATANAVGADLMISLRCETQTSVSANGVASFHFGNSHGSVSTIGRN
Mb3946|M.bovis_AF2122/97 DAERAATANAVGADLMISLRCETQTSLAANGVASFHFGNSHGSVSTIGRN
Rv3915|M.tuberculosis_H37Rv DAERAATANAVGADLMISLRCETQTSLAANGVASFHFGNSHGSVSTIGRN
MLBr_02704|M.leprae_Br4923 DSERAAIANNVGAELMISLRCETQTSPAANGVASFHFGNSHGSVSTIGRN
MAV_5303|M.avium_104 DAERAATANNVGADLMISLRCEAQKSPAANGVASFHFGNSHGSVSTIGRN
Mflv_0837|M.gilvum_PYR-GCK DAERAATANTVGADMMISLRCATQDSPAPNGVASFHFGNSHGSVSTIGRN
Mvan_6069|M.vanbaalenii_PYR-1 DAERAATANTVGADMMISLRCAAHPSPAANGVASFHFGNSHGSVSTIGRN
TH_2411|M.thermoresistible__bu DAERAATANTVGADLMISLRCAMHKSPAAHGVASFHFGNAHGSVSTIGRN
MSMEG_6935|M.smegmatis_MC2_155 DAERAQTANGVGADLMISLRCATQPSPAANGVASFYFGNSHGSVSTIGRN
MAB_4942|M.abscessus_ATCC_1997 DVERATYANNVGADLMISLRFDAQPTVAASGVASYHFGNLHGSVSTIGHM
* *** ** ***::***** : : :. ****::*** ********:
MMAR_5479|M.marinum_M LADFIQREVVARTGLQDCRTHGRTWDLLRLTRMPTVQVDIGYITNPLDRE
MUL_5068|M.ulcerans_Agy99 LADFIQREVVARTGLQDCRTHGRTWDLLRLTRMPTVQVDIGYITNPLDRE
Mb3946|M.bovis_AF2122/97 LADFIQREVVARTGLRDCRVHGRTWDLLRLTRMPTVQVDIGYITNPHDRG
Rv3915|M.tuberculosis_H37Rv LADFIQREVVARTGLRDCRVHGRTWDLLRLTRMPTVQVDIGYITNPHDRG
MLBr_02704|M.leprae_Br4923 LADFIQREIVARTGLRDCRTHGRTWDLLRLTRMPTVQIDIGYITNPRDRG
MAV_5303|M.avium_104 LADFIQREVVARTGLRDCRTHGRTWDLLRLTRMPTVQVDVGYVTNPHDRA
Mflv_0837|M.gilvum_PYR-GCK LADFIQREVVARTGLRDCRVHGRTWDLLRLTRMPTVQVDVGYISNPGDRA
Mvan_6069|M.vanbaalenii_PYR-1 LADFIQREVVARTGLRDCRVHGRTWDLLRLTRMPTVQVDVGYITNPGDRA
TH_2411|M.thermoresistible__bu LADFIQREIVARTGLQDCRTHGRTWDLLRLTRMPTVQVDIGYLTNPGDRA
MSMEG_6935|M.smegmatis_MC2_155 LADFIQREVVARTGLRDCRTHGRTWDLLRLTRMPTVQVDIGYITNPGDRG
MAB_4942|M.abscessus_ATCC_1997 LADFIQREVAARTGLRDCRAHGRTWDLLRLTRMPTVQVDIGYITSPHDVS
********:.*****:***.*****************:*:**::.* *
MMAR_5479|M.marinum_M LLVSTQTRDAIAEGILAAVKRLYLLGKNDRPTGTFTFAELLAHELSVERA
MUL_5068|M.ulcerans_Agy99 LLVSTQTRDAIAEGILAAVKRLYLLGKNDRPTGTFTFAELLAHELSVERA
Mb3946|M.bovis_AF2122/97 MLVSTQTRDAIAEGILAAVKRLYLLGKNDRPTGTFTFAELLAHELSVERA
Rv3915|M.tuberculosis_H37Rv MLVSTQTRDAIAEGILAAVKRLYLLGKNDRPTGTFTFAELLAHELSVERA
MLBr_02704|M.leprae_Br4923 VLIGTQNRDAIAEGILAAVKRLYLLGKNDQPTGTFTFAELLAHELSVERA
MAV_5303|M.avium_104 MLVSTQTRDAIAEGILAAVKRLYLLGKNDRPTGTFTFAELLAHELSVERT
Mflv_0837|M.gilvum_PYR-GCK TLVSPESRDALAEGILAAVKRLYLLGKNDRPTGTFTFAELLAHELSVEQA
Mvan_6069|M.vanbaalenii_PYR-1 TLVSATARDALAEGILAAVKRLYLLGKNDRPTGTFTFAELLAHELAVEQA
TH_2411|M.thermoresistible__bu LLTDPQIRDAIAEGILAAVKRLYLLGKNDRPTGTFTFAELLAHELSVEQS
MSMEG_6935|M.smegmatis_MC2_155 LLVSPQTRDAIAEGVLAAVKRLYLLGKNDRPTGTFTFAELLAHELSVEQA
MAB_4942|M.abscessus_ATCC_1997 ILSSAHYRDVVAESILAAVKRVYLLGKNDRPTGTFTFDELLAHELSAGS-
* .. **.:**.:******:*******:******* *******:.
MMAR_5479|M.marinum_M SRLSGS
MUL_5068|M.ulcerans_Agy99 SRLSGS
Mb3946|M.bovis_AF2122/97 GRLGGS
Rv3915|M.tuberculosis_H37Rv GRLGGS
MLBr_02704|M.leprae_Br4923 SRLGGS
MAV_5303|M.avium_104 SQMGGS
Mflv_0837|M.gilvum_PYR-GCK RRG---
Mvan_6069|M.vanbaalenii_PYR-1 RRV---
TH_2411|M.thermoresistible__bu GRMHSN
MSMEG_6935|M.smegmatis_MC2_155 GRGA--
MAB_4942|M.abscessus_ATCC_1997 ------