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M. thermoresistible (build 8) TH_2411 (-)

annotation: PROBABLE HYDROLASE
coordinates: 4710869 - 4712065
length: 399

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2411--100% (399)PROBABLE HYDROLASE
M. thermoresistible (build 8)TH_2289-6e-0725.24% (210) CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_0851-1e-0541.89% (74) CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3946-0.081.42% (393) putative hydrolase
M. gilvum PYR-GCKMflv_0837-0.085.79% (394) peptidoglycan binding domain-containing protein
M. tuberculosis H37RvRv3915-0.081.42% (393) hydrolase
M. leprae Br4923MLBr_02704-0.079.64% (393) putative hydrolase
M. abscessus ATCC 19977MAB_4942-1e-16473.90% (387) N-acetylmuramoyl-L-alanine amidase CwlM
M. marinum MMMAR_5479-0.082.70% (393) hydrolase
M. avium 104MAV_5303-0.083.21% (393) putative N-acetylmuramoyl-L-alanine amidase
M. smegmatis MC2 155MSMEG_6935-0.087.56% (394) N-acetylmuramoyl-L-alanine amidase
M. ulcerans Agy99MUL_5068-0.082.70% (393) hydrolase
M. vanbaalenii PYR-1Mvan_6069-0.086.58% (395) peptidoglycan binding domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0837|M.gilvum_PYR-GCK          MSS--------LRRGDRGGAVAEIRAALAALGMATDPDEDLSTGKHVAAD
Mvan_6069|M.vanbaalenii_PYR-1       MSS--------LRRGDRGGAVAEIRAALSALGMIDSPDEDLTTGKHVAAD
TH_2411|M.thermoresistible__bu      MSS--------LRRGDRGSAVAEIRAALAGLGLIDNPDDDLSTGRHVVPD
MSMEG_6935|M.smegmatis_MC2_155      MSS--------LRRGDRGGAVTEIRAALAALGLIENPDTDLSTGRHVALD
MMAR_5479|M.marinum_M               MPSPRREDGDTLRCGDRSAAVAEIRAALAALGMLDNPDEDLSTGRHIALE
MUL_5068|M.ulcerans_Agy99           MPSPRREDGDTLRCGDRSAAVAEIRAALAALGMLDNPDEDLSTGRHIALE
Mb3946|M.bovis_AF2122/97            MPSPRREDGDALRCGDRSAAVTEIRAALTALGMLDHQEEDLTTGRNVALE
Rv3915|M.tuberculosis_H37Rv         MPSPRREDGDALRCGDRSAAVTEIRAALTALGMLDHQEEDLTTGRNVALE
MLBr_02704|M.leprae_Br4923          MSSPRCEDGDTLRCGDRNAAVTEIRSALAALGLLHSPGDDLTTSKYIALD
MAV_5303|M.avium_104                MSSPRREYGDALRCGDRSAAVTEIRATLASLGLLASADEDLSTGRHVALE
MAB_4942|M.abscessus_ATCC_1997      MTTG----ASNIRHGDRGPAVTEVREVLTALGFLEDPDEVLATGRHVMVD
                                    *.:        :* ***. **:*:* .*:.**:       *:*.: :  :

Mflv_0837|M.gilvum_PYR-GCK          LFDDELDHAVRAFQQHRGLLVDGIVGEATYRALKEASYRLGARTLNHQFG
Mvan_6069|M.vanbaalenii_PYR-1       MFDDDLDHAVRAFQQHRGLLVDGIVGEATYRALKEASYRLGARTLNHQFG
TH_2411|M.thermoresistible__bu      YFDDELDQAVRAFQQQRGLLVDGVVGEATYRALKEASYRLGARTLSHQFG
MSMEG_6935|M.smegmatis_MC2_155      VFDDELDHAVRAFQQHRGLLVDGIVGEATYRALREASYRLGARILSHQFG
MMAR_5479|M.marinum_M               LFDPELDHAVRAFQQHRGLLVDGIVGEATYRALREASYRLGARTLYHQFG
MUL_5068|M.ulcerans_Agy99           LFDPELDHAVRAFQQHRGLLVDGIVGEATYRALREASYRLGARTLYHQFG
Mb3946|M.bovis_AF2122/97            LFDAQLDQAVRAFQQHRGLLVDGIVGEATYRALKEASYRLGARTLYHQFG
Rv3915|M.tuberculosis_H37Rv         LFDAQLDQAVRAFQQHRGLLVDGIVGEATYRALKEASYRLGARTLYHQFG
MLBr_02704|M.leprae_Br4923          LFDPQLEHAVRAFQQHRGLLVDGVVGEATHRALKEASYRLGARTLYHRFG
MAV_5303|M.avium_104                LFDAELDQAVRAFQQHRGLLVDGIVGEATYRALKEASYRLGARTLYHQFG
MAB_4942|M.abscessus_ATCC_1997      RFDATLDDAVRAFQQCRGLLVDGIVGPATYRTLKEASYRLGARTLFHQFS
                                     **  *:.******* *******:** **:*:*:********* * *:*.

Mflv_0837|M.gilvum_PYR-GCK          APMYGDDVATLQARLQDLGFYTGLVDGHFGLQTHNALSSYQREYGLYPDG
Mvan_6069|M.vanbaalenii_PYR-1       APMYGDDVATLQSRLQDLGFYTGLVDGHFGLQTHNALSSYQREYGLYPDG
TH_2411|M.thermoresistible__bu      APMYGDDVATLQLRLQELGFYTGLVDGHFGLQTHNALMSYQREYGLYPDG
MSMEG_6935|M.smegmatis_MC2_155      APMYGDDVATLQARLQDLGFYTGLVDGYFGLQTHNALMSYQREYGLYPDG
MMAR_5479|M.marinum_M               APLYGDDVATLQARLQDLGFYTGLVDGYFGLQTHNALMSYQREYGMSADG
MUL_5068|M.ulcerans_Agy99           APLYGDDVATLQARLQDLGFYTGLVDGYFGLQTHNALMSYQREYGMSADG
Mb3946|M.bovis_AF2122/97            APLYGDDVATLQARLQDLGFYTGLVDGHFGLQTHNALMSYQREYGLAADG
Rv3915|M.tuberculosis_H37Rv         APLYGDDVATLQARLQDLGFYTGLVDGHFGLQTHNALMSYQREYGLAADG
MLBr_02704|M.leprae_Br4923          APLSGDDVATLQARLQDLGFYTGMVDGHFGLQTHNALISYQREYGLTADG
MAV_5303|M.avium_104                APLYGDDVATLQARLQDLGFYTGLVDGYFGLQTHNALMSYQREYGLSADG
MAB_4942|M.abscessus_ATCC_1997      APMYGDDVATLQKRLQDLGFYTGLVDGNFGLQTYNSLMSYQREYGLTADG
                                    **: ******** ***:******:*** *****:*:* *******: .**

Mflv_0837|M.gilvum_PYR-GCK          ICGPETLRSLYFLGARVTGGSPHAIREEELVRSSGPRLSGKRIIVDPGRG
Mvan_6069|M.vanbaalenii_PYR-1       ICGPETLRSLYFLGSRVTGGSPHAIREEELVRRSGPRLSGKRIIIDPGRG
TH_2411|M.thermoresistible__bu      ICGPETLRSLYFLGSRVTGGSPHAIREEEMVRRSGPRLSGKRIIIDPGLG
MSMEG_6935|M.smegmatis_MC2_155      ICGPETLRSLYFLGSRVTGGSPHAIREEELVRRSGPRLSGKRVIIDPGRG
MMAR_5479|M.marinum_M               ICGPETLRSLYFLSSRVSGGSPHAIREEELVRRSGPKLSGKRIIIDPGRG
MUL_5068|M.ulcerans_Agy99           ICGPETLRSLYFLSSRVSGGSPHAIREEELVRRSGPKLSGKRIIIDPGRG
Mb3946|M.bovis_AF2122/97            ICGPETLRSLYFLSSRVSGGSPHAIREEELVRSSGPKLSGKRIIIDPGRG
Rv3915|M.tuberculosis_H37Rv         ICGPETLRSLYFLSSRVSGGSPHAIREEELVRSSGPKLSGKRIIIDPGRG
MLBr_02704|M.leprae_Br4923          ICGPETLRSLYFLSSRVTGGSPHAIREEELVRRSGPKLSGKRIIIDPGRG
MAV_5303|M.avium_104                ICGPETLRSLYFLSSRVTGGSPHALREEELVRRSGPKLSGKRIIIDPGRG
MAB_4942|M.abscessus_ATCC_1997      ICGPETLRSFQLLGRHVTGGSAHAIRETEHVRNAGPQLSGKRIVIDPGLG
                                    *********: :*. :*:***.**:** * ** :**:*****:::*** *

Mflv_0837|M.gilvum_PYR-GCK          GSDHGVIVNGPDGPISEADILWDLASRLEGRMTAIGIETFLSRSANSSPT
Mvan_6069|M.vanbaalenii_PYR-1       GSDHGLIMNGPAGPISEADILWDLASRLEGRMTAIGIETFLSRSAHTSAS
TH_2411|M.thermoresistible__bu      GSERGLIMSTPRGPISEADILWDLASRLEGRMTAIGMETSLSRSAHHCPT
MSMEG_6935|M.smegmatis_MC2_155      GSDHGLIMQGPHGPISEADILWDLASRLEGRMTAIGMDTVLSRPPNRSPS
MMAR_5479|M.marinum_M               GSDRGLIAHGEAGPVSEADVLWDLASRLEGRMSAIGMETFLSRPANTSPS
MUL_5068|M.ulcerans_Agy99           GSDRGVIAHGEAGPISEADVLWDLASRLEGRMSAIGMETFFSRPANTSPS
Mb3946|M.bovis_AF2122/97            GVDHGLIAQGPAGPISEADLLWDLASRLEGRMAAIGMETHLSRPTNRSPS
Rv3915|M.tuberculosis_H37Rv         GVDHGLIAQGPAGPISEADLLWDLASRLEGRMAAIGMETHLSRPTNRSPS
MLBr_02704|M.leprae_Br4923          GADRGLITQGPTGPISEADVLWDLASRLEGRMAAIGIETFLSRTTNGSPS
MAV_5303|M.avium_104                GADHGMIMQGPSGPISEADVLWDLASRLEGRMTAIGMETFLSRPVNRSPL
MAB_4942|M.abscessus_ATCC_1997      GGDRGRIVPGREGPTSEADILWDLASRLEGRMTAIGMDTYISRAIQNNPT
                                    * ::* *     ** ****:************:***::* :**. :  . 

Mflv_0837|M.gilvum_PYR-GCK          DAERAATANTVGADMMISLRCATQDSPAPNGVASFHFGNSHGSVSTIGRN
Mvan_6069|M.vanbaalenii_PYR-1       DAERAATANTVGADMMISLRCAAHPSPAANGVASFHFGNSHGSVSTIGRN
TH_2411|M.thermoresistible__bu      DAERAATANTVGADLMISLRCAMHKSPAAHGVASFHFGNAHGSVSTIGRN
MSMEG_6935|M.smegmatis_MC2_155      DAERAQTANGVGADLMISLRCATQPSPAANGVASFYFGNSHGSVSTIGRN
MMAR_5479|M.marinum_M               DAERAATANAVGADLMISLRCETQTTVSANGVASFHFGNSHGSVSTIGRN
MUL_5068|M.ulcerans_Agy99           DAERAATANAVGADLMISLRCETQTSVSANGVASFHFGNSHGSVSTIGRN
Mb3946|M.bovis_AF2122/97            DAERAATANAVGADLMISLRCETQTSLAANGVASFHFGNSHGSVSTIGRN
Rv3915|M.tuberculosis_H37Rv         DAERAATANAVGADLMISLRCETQTSLAANGVASFHFGNSHGSVSTIGRN
MLBr_02704|M.leprae_Br4923          DSERAAIANNVGAELMISLRCETQTSPAANGVASFHFGNSHGSVSTIGRN
MAV_5303|M.avium_104                DAERAATANNVGADLMISLRCEAQKSPAANGVASFHFGNSHGSVSTIGRN
MAB_4942|M.abscessus_ATCC_1997      DVERATYANNVGADLMISLRFDAQPTVAASGVASYHFGNLHGSVSTIGHM
                                    * ***  ** ***::*****   : : :. ****::*** ********: 

Mflv_0837|M.gilvum_PYR-GCK          LADFIQREVVARTGLRDCRVHGRTWDLLRLTRMPTVQVDVGYISNPGDRA
Mvan_6069|M.vanbaalenii_PYR-1       LADFIQREVVARTGLRDCRVHGRTWDLLRLTRMPTVQVDVGYITNPGDRA
TH_2411|M.thermoresistible__bu      LADFIQREIVARTGLQDCRTHGRTWDLLRLTRMPTVQVDIGYLTNPGDRA
MSMEG_6935|M.smegmatis_MC2_155      LADFIQREVVARTGLRDCRTHGRTWDLLRLTRMPTVQVDIGYITNPGDRG
MMAR_5479|M.marinum_M               LADFIQREVVARTGLQDCRTHGRTWDLLRLTRMPTVQVDIGYITNPLDRE
MUL_5068|M.ulcerans_Agy99           LADFIQREVVARTGLQDCRTHGRTWDLLRLTRMPTVQVDIGYITNPLDRE
Mb3946|M.bovis_AF2122/97            LADFIQREVVARTGLRDCRVHGRTWDLLRLTRMPTVQVDIGYITNPHDRG
Rv3915|M.tuberculosis_H37Rv         LADFIQREVVARTGLRDCRVHGRTWDLLRLTRMPTVQVDIGYITNPHDRG
MLBr_02704|M.leprae_Br4923          LADFIQREIVARTGLRDCRTHGRTWDLLRLTRMPTVQIDIGYITNPRDRG
MAV_5303|M.avium_104                LADFIQREVVARTGLRDCRTHGRTWDLLRLTRMPTVQVDVGYVTNPHDRA
MAB_4942|M.abscessus_ATCC_1997      LADFIQREVAARTGLRDCRAHGRTWDLLRLTRMPTVQVDIGYITSPHDVS
                                    ********:.*****:***.*****************:*:**::.* *  

Mflv_0837|M.gilvum_PYR-GCK          TLVSPESRDALAEGILAAVKRLYLLGKNDRPTGTFTFAELLAHELSVEQA
Mvan_6069|M.vanbaalenii_PYR-1       TLVSATARDALAEGILAAVKRLYLLGKNDRPTGTFTFAELLAHELAVEQA
TH_2411|M.thermoresistible__bu      LLTDPQIRDAIAEGILAAVKRLYLLGKNDRPTGTFTFAELLAHELSVEQS
MSMEG_6935|M.smegmatis_MC2_155      LLVSPQTRDAIAEGVLAAVKRLYLLGKNDRPTGTFTFAELLAHELSVEQA
MMAR_5479|M.marinum_M               LLVSTQTRDAIAEGILAAVKRLYLLGKNDRPTGTFTFAELLAHELSVERA
MUL_5068|M.ulcerans_Agy99           LLVSTQTRDAIAEGILAAVKRLYLLGKNDRPTGTFTFAELLAHELSVERA
Mb3946|M.bovis_AF2122/97            MLVSTQTRDAIAEGILAAVKRLYLLGKNDRPTGTFTFAELLAHELSVERA
Rv3915|M.tuberculosis_H37Rv         MLVSTQTRDAIAEGILAAVKRLYLLGKNDRPTGTFTFAELLAHELSVERA
MLBr_02704|M.leprae_Br4923          VLIGTQNRDAIAEGILAAVKRLYLLGKNDQPTGTFTFAELLAHELSVERA
MAV_5303|M.avium_104                MLVSTQTRDAIAEGILAAVKRLYLLGKNDRPTGTFTFAELLAHELSVERT
MAB_4942|M.abscessus_ATCC_1997      ILSSAHYRDVVAESILAAVKRVYLLGKNDRPTGTFTFDELLAHELSAGS-
                                     * ..  **.:**.:******:*******:******* *******:.   

Mflv_0837|M.gilvum_PYR-GCK          RRG---
Mvan_6069|M.vanbaalenii_PYR-1       RRV---
TH_2411|M.thermoresistible__bu      GRMHSN
MSMEG_6935|M.smegmatis_MC2_155      GRGA--
MMAR_5479|M.marinum_M               SRLSGS
MUL_5068|M.ulcerans_Agy99           SRLSGS
Mb3946|M.bovis_AF2122/97            GRLGGS
Rv3915|M.tuberculosis_H37Rv         GRLGGS
MLBr_02704|M.leprae_Br4923          SRLGGS
MAV_5303|M.avium_104                SQMGGS
MAB_4942|M.abscessus_ATCC_1997      ------