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PPTDPPPTGQLDPRYAENPAWEQQWAKVPAAWRAPVYQIDTAPFNEVFVQNRYYTTATPGYDGYDFTPPG PPRFAHELAWWVYTCWREGLRRIDPAKIVWFTQALPEAAAEYRRRRGRSPASLLDITVPDIVRHATVLFE QRRHRLPTPSYRRNLEWTVEHLHTLLAVRCTPAPWWSYDTWDLRIDPRIPQREHEPHHERVLKLAGIQPV WLREGLRFWMRTAITHQLFTWTTAVSRCQTLGRHLGLFCQHNNYRDDPLITADPEQLRAVFMDFLTYLRS PEATTKSGTLSDYLVAEIQYQVQAFYTFMHDHGAEAAAATGEKRWKKLGISHTRLWAPAYLPRKTHRSRE LTWYSTADLQRMLAYLEVLGADTEERVVLTHPDGQISVMAGLGDPQAARAWLLQAMTGRRASEILMLDHD PLQAIPGAAAPAGADTGIFVARLRYQQTKVAGVDPTILVEQQIVDVIREQQRWLSRHYPGMKPKYLFVGM VHQHQGQRARPYTSYLNALKKLDGVHRLVDTQGNPLRFSQTHRLRHTRATELLNDGVPFHVVQRYLGHKS PEMTARYAATLAATSEAEFLKHKKIGAMGADIAISPSDIYEMTQLGKRTDRVLPNGVCLLPPLKSCDKGN ACLSCGHFATDATHLADLRDQLTATETLLAGRRQQFADRTGRELTDDNVWVSERLREIASLQAIITRLSD QANTLAHNRSGDIAVAGPATAGRRPQLPILTRGAHETTINHASGHRHCDD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4874c | - | - | 100% (751) | putative transposase/phage integrase |
| M. abscessus ATCC 19977 | MAB_0443 | - | 0.0 | 68.49% (749) | putative transposase/integrase |
| M. abscessus ATCC 19977 | MAB_0442 | - | 7e-09 | 25.32% (316) | putative transposase/integrase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4644 | - | 1e-16 | 29.39% (313) | phage integrase family protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_0504 | - | 0.0 | 60.94% (663) | putative transposase |
| M. smegmatis MC2 155 | MSMEG_4156 | - | 1e-20 | 31.03% (261) | putative transposase |
| M. thermoresistible (build 8) | TH_3646 | - | 0.0 | 62.05% (730) | PUTATIVE phage integrase family protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5419 | - | 0.0 | 60.62% (744) | phage integrase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3646|M.thermoresistible__bu ---------------VAGLGSWEAQWAQVPAAWRRPVYPIYAAPYDEVFL
Mvan_5419|M.vanbaalenii_PYR-1 ---MDPPPPRGAASSPVAVSSWQSQWARVPGQWRKPVYPIDTAPFQEVFL
MAV_0504|M.avium_104 --------------------------------------------------
MAB_4874c|M.abscessus_ATCC_199 MPPTDPPPTGQLDPRYAENPAWEQQWAKVPAAWRAPVYQIDTAPFNEVFV
MSMEG_4156|M.smegmatis_MC2_155 ---------MTALDPNSTLGLLGRLMAGVRSEFRRDVLEFAAD-------
Mflv_4644|M.gilvum_PYR-GCK ------------MLPEHDYAPTPETPAQIYAAYLVHLQ------------
TH_3646|M.thermoresistible__bu RNQFYLRANRATAAHDFTPAAPSRFAEEIAWWVWLCWDQQLRRIEPSLLA
Mvan_5419|M.vanbaalenii_PYR-1 RNQFYLRGNRAGAAHDFTPAAPPRFAEEIAWWVWWCWDQQLRKIEPSLLA
MAV_0504|M.avium_104 --------------------------------MWLCHHEGLRRIEPSVLK
MAB_4874c|M.abscessus_ATCC_199 QNRYYTTATPGYDGYDFTPPGPPRFAHELAWWVYTCWREGLRRIDPAKIV
MSMEG_4156|M.smegmatis_MC2_155 -DAVFGGGSCRVTDCGRSARGHGLCQGHHQRWANAGRPDLEEFTVSTDPR
Mflv_4644|M.gilvum_PYR-GCK ------RRDRGNTAYAQAARSFLRRWPRVQSWADIPLDEQLAANCSTRPF
: .:
TH_3646|M.thermoresistible__bu WLVRTLPGAVAEHSARTGHPPVSIADLDPTELIRQ-----AALAFQRRNN
Mvan_5419|M.vanbaalenii_PYR-1 WLVRTLPAAISEHTTRTGAAPTSIAELDPTELIRQ-----AALSFQRRNN
MAV_0504|M.avium_104 WAGQALTAAAADYRNTHGHQPTSITDLSAATIVRH-----AMLVFEKRNA
MAB_4874c|M.abscessus_ATCC_199 WFTQALPEAAAEYRRRRGRSPASLLDITVPDIVRH-----ATVLFEQRRH
MSMEG_4156|M.smegmatis_MC2_155 WRKHRPNQACRVDGCGYGSARGGLCQLHAQRWERAGRPHLASWLRDPLPV
Mflv_4644|M.gilvum_PYR-GCK VTFLMVSRRLQPGYDYLVHRKLSSLWHELTDSCLQP-------DLDQFIS
. :
TH_3646|M.thermoresistible__bu RLPSAGSRRNIRHLIEHLHLAVAVRCTDAPWWSHDIWDLRADPRIPQRPH
Mvan_5419|M.vanbaalenii_PYR-1 RLPSPGSRRNISHLIEHLHLNVSVSCTDTPWWAHDIWDLRADPRIPQRPH
MAV_0504|M.avium_104 RLPSPGARRNVTHLIEHLHLYLSVRTTDTDWWAHDTWDLRADPRIPQREH
MAB_4874c|M.abscessus_ATCC_199 RLPTPSYRRNLEWTVEHLHTLLAVRCTPAPWWSYDTWDLRIDPRIPQREH
MSMEG_4156|M.smegmatis_MC2_155 KQPRPGATCRIRHCSLWPQAESPLCHSHTNTWKANGRTDIDGFVTRFESN
Mflv_4644|M.gilvum_PYR-GCK AALELGFTERVASAIGSQIIARLLIQTGRPLTGLRESDLQELLHACHVRQ
. .: : : :
TH_3646|M.thermoresistible__bu EPHHDQAVRLRGIEPVWLREGLRFWLRSALTYDLLTWSSVVSRAR-----
Mvan_5419|M.vanbaalenii_PYR-1 EPCHDQTVRLRGITPDWLREGLRFWLRSALTYDLLTWSSVVDRAR-----
MAV_0504|M.avium_104 EPGHDQSVKIGAITPDWLREGVRFWLRTALDAELLRWSSAVERAR-----
MAB_4874c|M.abscessus_ATCC_199 EPHHERVLKLAGIQPVWLREGLRFWMRTAITHQLFTWTTAVSRCQ-----
MSMEG_4156|M.smegmatis_MC2_155 DTPANETIQLGMLTPQLKLEMQYVLQQRHDDRRGKLTPTVVARVVRLLID
Mflv_4644|M.gilvum_PYR-GCK ERTGRGAKHYRSTTHSARQILFHLGILDTQARPAVTALTLEQRMVD----
: : . : *
TH_3646|M.thermoresistible__bu NIGSQLGRFARDRGYLHDPLISTDPDELREAFLGYLEYLRSPQAATQSER
Mvan_5419|M.vanbaalenii_PYR-1 NLGSQLGHFATTAGHLQDPLISTDPDQLRTVFLDYLDYLRSPQAATHSER
MAV_0504|M.avium_104 DMARHFGAFATEHG-YADPALADDPAQLRLIFTAFTEYLRSPAAAATPDK
MAB_4874c|M.abscessus_ATCC_199 TLGRHLGLFCQHNNYRDDPLITADPEQLRAVFMDFLTYLRSPEATTKSGT
MSMEG_4156|M.smegmatis_MC2_155 TATTSLLDFDADEWRQRSAVLLNDTRSRGLLLYAHSTVLDLAEAGG-WEA
Mflv_4644|M.gilvum_PYR-GCK VPVALRPAFVAYLNRKYATCVPKTVSSLATRLAHFGRYLAAADPSLTSLN
* . : . : . * . .
TH_3646|M.thermoresistible__bu -LTPYTVASLQSETQSFYTFMHDHAAEAAAGTGNLRWREATLTH------
Mvan_5419|M.vanbaalenii_PYR-1 -LTSDTVASLQAQTQSFYTFMHDHAAEAATATATARWRDITLTH------
MAV_0504|M.avium_104 PLTPSAIDATQSYTQVFYTFMVDHAPEAAAATGNPRWLALTDAH------
MAB_4874c|M.abscessus_ATCC_199 -LSDYLVAEIQYQVQAFYTFMHDHGAEAAAATGEKRWKKLGISH------
MSMEG_4156|M.smegmatis_MC2_155 EYPRDVWRMHRLGYEGHYTLRFDRIPQPWLREPAKRWIRLRLSRGLNLEA
Mflv_4644|M.gilvum_PYR-GCK --QLDRRRHIEPFITSLTTATNSVTGEPITVADRIRCIHAVGNF------
. * . :. *
TH_3646|M.thermoresistible__bu ---TALWSPIHAPRRQRSE--RDLTWYSTADLQRMLTYLDVLAADRKQKV
Mvan_5419|M.vanbaalenii_PYR-1 ---TALWSPINAPKHRRRA--RELTWHSTADLQRMLAYLDVLAAEPKQKV
MAV_0504|M.avium_104 ---TRLWGPAFRARRANRV--RELSWYSTGELQQMLAYLDVLAADRGTLV
MAB_4874c|M.abscessus_ATCC_199 ---TRLWAPAYLPRKTHRS--RELTWYSTADLQRMLAYLEVLGADTEERV
MSMEG_4156|M.smegmatis_MC2_155 GGGRPLLAIARFGRFLAEVDIEDISRIDRELLERYLAHLNREYSPQRRGA
Mflv_4644|M.gilvum_PYR-GCK -----LAEITEWGWDDAPPR-RLIFRTDLPRPPRCLPRYLPVDSDRKLTA
* . : . : *. : .
TH_3646|M.thermoresistible__bu VMTRPDGTLTVLPG---LGDPQAARIWLLQALTGRRASEILMLDYDPLEA
Mvan_5419|M.vanbaalenii_PYR-1 VLTGPDGDLSVLAG---LGDPQAARIWLLQALTGRRASEILMLDYDPLEA
MAV_0504|M.avium_104 ALTHPDGTASIIKG---LGDPQAARIWLLQALTGRRASEILMLDHQPLQP
MAB_4874c|M.abscessus_ATCC_199 VLTHPDGQISVMAG---LGDPQAARAWLLQAMTGRRASEILMLDHDPLQA
MSMEG_4156|M.smegmatis_MC2_155 HIGLLNGFFAAIRQHCWATGLPATAMFFAEDHPKRGEHLPRALAEHVMTQ
Mflv_4644|M.gilvum_PYR-GCK ALAKSP-------------YRLAADALLVQRACGLRIGELLDLELDCIHE
: *: : : * . :
TH_3646|M.thermoresistible__bu IPGRDRPTDAAEPDSGAFVARLRYQQTKVDGVIPT---------------
Mvan_5419|M.vanbaalenii_PYR-1 IPGQDRPVG-TEPDNGAFVARLRYQQTKVDGIVPT---------------
MAV_0504|M.avium_104 IPGAERPTDSDDPD--AFVAKLRYQQTKVDDVTPT---------------
MAB_4874c|M.abscessus_ATCC_199 IPGAAAPAG---ADTGIFVARLRYQQTKVAGVDPT---------------
MSMEG_4156|M.smegmatis_MC2_155 LEHRDNLDRFNNPVYRLITVILMRCGLRITDALRLRGDCVTTDANGAPYL
Mflv_4644|M.gilvum_PYR-GCK IPGQG--------------SWLKVPLGKLN--SER---------------
: * ::
TH_3646|M.thermoresistible__bu ------------ILVEQAIVDIITEQQAWLKSKYPALQPKYLFLGIKNQH
Mvan_5419|M.vanbaalenii_PYR-1 ------------ILVEQAIVDIIGEQQRWLTTKYPQLQSKYLFLGLKNQH
MAV_0504|M.avium_104 ------------ILVEQAVVNVVTEQQRWLTTTYPGLTPKYLFIGVKQNL
MAB_4874c|M.abscessus_ATCC_199 ------------ILVEQQIVDVIREQQRWLSRHYPGMKPKYLFVGMVHQH
MSMEG_4156|M.smegmatis_MC2_155 RYFNHKMKRDALVPIAPDLVDMIGYQRRLVSERWPDGT-ALLFPRPTKNI
Mflv_4644|M.gilvum_PYR-GCK -----------MIPVDDEVLTLVDRITTTRSSGRPMIHPRTGAPADFLFT
: : :: :: . *
TH_3646|M.thermoresistible__bu RGQRPRSYTTYRAMLDKLDQCHDLTDSAGRPLRFTQTHRLRHTRATELLN
Mvan_5419|M.vanbaalenii_PYR-1 RGQRPRSYTTYRAMLDKLDKCHTLTDSAGRALRFTQTHRLRHTRATELLN
MAV_0504|M.avium_104 AGRRPRPYASYNLSLAKLDNIHGLTDAAGNPLRFTQTHRLRHTRATELLN
MAB_4874c|M.abscessus_ATCC_199 QGQRARPYTSYLNALKKLDGVHRLVDTQGNPLRFSQTHRLRHTRATELLN
MSMEG_4156|M.smegmatis_MC2_155 DGQIPLAIPTYREALHRWLAVCDIRDEHSDPVHLTP-HQWRHTLGTRLIN
Mflv_4644|M.gilvum_PYR-GCK HHGKRLSQNAVREELNRAAQAASLGHITP--------HQLRHTYATALIN
. : * : : . *: *** .* *:*
TH_3646|M.thermoresistible__bu DGVPFHVVQRYLGHKSPEMTARYAATLAATAEAEFLKHKKIGAHGADIDI
Mvan_5419|M.vanbaalenii_PYR-1 DGVPFHVVQRYLGHKSPEMTARYAATLAATAEAEFLKHKKIGAHGADIDI
MAV_0504|M.avium_104 DGVPIHVVQRYLGHKSPEMTMRYASTLAATAEAEFLKHKKIGAHGVEIAI
MAB_4874c|M.abscessus_ATCC_199 DGVPFHVVQRYLGHKSPEMTARYAATLAATSEAEFLKHKKIGAMGADIAI
MSMEG_4156|M.smegmatis_MC2_155 RDVPQEVVRRILDHDSPQMTAHYARLHDTTVRRAWEAARKVDSHGREVNL
Mflv_4644|M.gilvum_PYR-GCK AGVSLQALMALLGHVSTQMSLRYAHLFDHTVRTEYERALDLAKSHIGALP
.*. ..: *.* *.:*: :** * . : .:
TH_3646|M.thermoresistible__bu TPHD---IYEMTQLAKR----TDRVLPNGVCLLPPLK-SCDKGNACLSCG
Mvan_5419|M.vanbaalenii_PYR-1 TPHD---IYEMTQLAAR----TDRVLPNGVCLLPPLK-QCDKGNACLGCG
MAV_0504|M.avium_104 SPSD---ILDMTQLSAR----TDRVLPNGVCLLPPLK-TCDKGNACLSCG
MAB_4874c|M.abscessus_ATCC_199 SPSD---IYEMTQLGKR----TDRVLPNGVCLLPPLK-SCDKGNACLSCG
MSMEG_4156|M.smegmatis_MC2_155 DPDG---PLAEAAWAKQRLGRATQALPNGYCGLPVQQ-SCPHANACLTCP
Mflv_4644|M.gilvum_PYR-GCK KTAVGLPITDITGTGWKDTPAIKSRLAGGYCLRAPAQGSCPYANICEHCP
. : . : *..* * . : * .* * *
TH_3646|M.thermoresistible__bu HFATDATHLAELRQQLASTQTLIAQRQDQYRQRSGRELGEDNIWIIERRR
Mvan_5419|M.vanbaalenii_PYR-1 HFATDTTHLDELRAQLAATEALIATRRDQYRQRAGRELGDDNIWIIERHR
MAV_0504|M.avium_104 HFATDITHAAELRDQHTKTAALIELRRQQYRQRTGRELTDDNVWIRERLR
MAB_4874c|M.abscessus_ATCC_199 HFATDATHLADLRDQLTATETLLAGRRQQFADRTGRELTDDNVWVSERLR
MSMEG_4156|M.smegmatis_MC2_155 MFLTTQEFLPQHRTQREQTLHLITAAEARGHQR----------LAEMNRQ
Mflv_4644|M.gilvum_PYR-GCK SFHTDSTHLAVLAAQRIDAQDLAADAEKRGWID----------EAERHHN
* * . * : * . : . .
TH_3646|M.thermoresistible__bu EIASLQAIIDRLTTEEAG---------SVAGAGAAKRLPLLQIQTRGAHQ
Mvan_5419|M.vanbaalenii_PYR-1 EIDSLHAIIDRLAATADN---------SVAGPGTGKRLPLLQIQTRGAHQ
MAV_0504|M.avium_104 ELNSLQAILERLAADAGTPES------AISGAGTFRRLPLHVIATRGAHD
MAB_4874c|M.abscessus_ATCC_199 EIASLQAIITRLSDQANTLAHNRSGDIAVAGPATAGRRPQLPILTRGAHE
MSMEG_4156|M.smegmatis_MC2_155 VLGNLDAIITSLDTPTDP---------------------------KAAEH
Mflv_4644|M.gilvum_PYR-GCK LVSRLDALITGSASA-----------------------------------
: *.*::
TH_3646|M.thermoresistible__bu SALDKARRRRTGEP
Mvan_5419|M.vanbaalenii_PYR-1 SALDKASRPRTGEQ
MAV_0504|M.avium_104 SALRKADPRADA--
MAB_4874c|M.abscessus_ATCC_199 TTINHASGHRHCDD
MSMEG_4156|M.smegmatis_MC2_155 AS------------
Mflv_4644|M.gilvum_PYR-GCK --------------