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SSSAYDRFVDHVSRRYAVPCNDYEDMWRWSVESVPQFWRALWEFFEVPGRGLRDGDAGVLANSAMPAAQW FPGVELNYVAQMLRHVHRDGAAIVGVDEAGERSEISWRELPGRIGAVAAELRRLGVGRGDCVAAYLPDVP DAMVAFLATASVGAVWAGCGQDYAPEGAAARLAQLTPKVLISGRGYRYNGRWVSKQADTEVLHRLLPGEP ALIIELPTGSEDPVVEMVPFDHPIWVLFSSGTTGKPKGIVHGHGGMLLEHLKGAGLHCDLGPGDVFFWQT ALSWMMWNFRLAGLLVGATVVCYSGHPLYPNADRLWELLEAERVTYFGTSPGHLHASKKAGLEPSSEHDL AVLKTLGSSGSPLSADLFQWAGAHTGATVSSLSGGTDVCTAFAGGTPEVPTHPGELPARYLGVDLHSWSP DRRSLIGEVGEMVILQPMPCMPIRFWDDPDGSRYKAAYFEHEWADGQAPGVWRHGDWVTVTERGSLVIHG RSDATLNRNGIRMGSADIYEVVESMDQIAEGFVLGVDGPNGAYWMPLFITMAPGHTFDDALGDQVAREIR DRLSPRHVPDEVIEAPGIPHTRTGKKLEVPICGVLAGRVDVSLDPRSIDNPDLVDWYRERGRDHRW*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_4376c | - | - | 100% (627) | putative acetoacetyl-CoA synthetase |
M. abscessus ATCC 19977 | MAB_0425c | - | 5e-49 | 27.67% (636) | Acetyl-CoA synthetase |
M. abscessus ATCC 19977 | MAB_4099c | - | 9e-17 | 25.34% (509) | non-ribosomal peptide synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3691 | acs | 4e-49 | 28.19% (596) | acetyl-CoA synthetase |
M. gilvum PYR-GCK | Mflv_1473 | - | 0.0 | 52.83% (619) | acetoacetyl-CoA synthetase |
M. tuberculosis H37Rv | Rv3667 | acs | 3e-49 | 28.19% (596) | acetyl-CoA synthetase |
M. leprae Br4923 | MLBr_00134 | fadD22 | 8e-11 | 22.65% (499) | acyl-CoA synthetase |
M. marinum M | MMAR_5155 | acs | 2e-47 | 28.40% (567) | acetyl-coenzyme A synthetase Acs |
M. avium 104 | MAV_0462 | acsA | 2e-47 | 28.04% (567) | acetyl-CoA synthetase |
M. smegmatis MC2 155 | MSMEG_6024 | - | 0.0 | 50.71% (637) | acetoacetyl-CoA synthetase |
M. thermoresistible (build 8) | TH_4609 | - | 1e-157 | 44.83% (629) | PUTATIVE putative acetoacetyl-CoA synthase |
M. ulcerans Agy99 | MUL_4241 | acs | 1e-46 | 28.22% (567) | acetyl-CoA synthetase |
M. vanbaalenii PYR-1 | Mvan_5298 | - | 0.0 | 50.89% (617) | acetoacetyl-CoA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_1473|M.gilvum_PYR-GCK ----MERSVTEPQWTPAERDIAEAEITAFTRFVEQRTGRDFPDYHALWAW Mvan_5298|M.vanbaalenii_PYR-1 ----MTVTTIEAQWVPSDRDIAEAQVTRFARFAEERTGKTFADYHALWQW MSMEG_6024|M.smegmatis_MC2_155 --------MTAPQWEPTQSDIDSARVTDFARYVESRTGVSAPDYQALWRW MAB_4376c|M.abscessus_ATCC_199 --------------------MSSSAYDRFVDHVSRRYAVPCNDYEDMWRW TH_4609|M.thermoresistible__bu -----------VLWTPTAERIEASRIADFQRWLAAERGVRTTDYASLWRW Mb3691|M.bovis_AF2122/97 -------------------MSESTPEVSSSYPPPAHFAEHANARAELYRE Rv3667|M.tuberculosis_H37Rv -------------------MSESTPEVSSSYPPPAHFAEHANARAELYRE MMAR_5155|M.marinum_M -------------------MTATSAEEPSSYPPPAEFIEQANARAELYRE MUL_4241|M.ulcerans_Agy99 ----------MKLNIGDTPVTATSAEEPSSYPPPAEFIEQANARAELYRE MAV_0462|M.avium_104 -------------------MTASNTANPPSYPPPPQFVEQANAGEQLYRE MLBr_00134|M.leprae_Br4923 MRSENLAALLARQAAEAGWYDKPAYFAPDVVTHGQIHDGAVRLGEVLRNR : Mflv_1473|M.gilvum_PYR-GCK SVEDVEEFWAALWDYFDLG-----ERAQPVLQSAEMPGAQ----WFPG-- Mvan_5298|M.vanbaalenii_PYR-1 SVDDVEAFWGALWDYFDLG-----ERAD-VLDGAEMPGAR----WFPG-- MSMEG_6024|M.smegmatis_MC2_155 SVEDPGAFWAAVWDYFDLG-----ERPDQVLTTGEMPGSR----WFPG-- MAB_4376c|M.abscessus_ATCC_199 SVESVPQFWRALWEFFEVPGRGLRDGDAGVLANSAMPAAQ----WFPG-- TH_4609|M.thermoresistible__bu SISDLDGFWSSIWDYFDVIG----IRGDTALAKAEMPGAD----WFPG-- Mb3691|M.bovis_AF2122/97 AEEDRLAFWAKQANRLSWTT-----PFTEVLDWSEAPFAK----WFVGGE Rv3667|M.tuberculosis_H37Rv AEEDRLAFWAKQANRLSWTT-----PFTEVLDWSGAPFAK----WFVGGE MMAR_5155|M.marinum_M AEEDRLAFWAKQADRLSWAT-----PFGEVLDWSDAPFAK----WFVGGK MUL_4241|M.ulcerans_Agy99 AEEDRLAFWAKQADRLSWAT-----PFGEVLDWSDAPFAN----WFVGGK MAV_0462|M.avium_104 AERDRLAFWAEQANRLSWAT-----PFTEVLDWSRAPFAE----WFADGT MLBr_00134|M.leprae_Br4923 GLSAGDRVLLCLPDSPDLVQLLLACLARGIMAFLANPELHRDDYAFPERD . . : . : * * Mflv_1473|M.gilvum_PYR-GCK --TEINYVDQVMRHVRTDRPAILHVSED-APDREVSWAELLGRTAAFADR Mvan_5298|M.vanbaalenii_PYR-1 --ATLNYVDQVVRQARTDRPAIIHVSED-GSDREVSWAELLGRAAAFAER MSMEG_6024|M.smegmatis_MC2_155 --AKLNYVDQVKRNARTDRPAILYVAEG-GAVTDISWKELLGRTAAFADA MAB_4376c|M.abscessus_ATCC_199 --VELNYVAQMLRHVHRDGAAIVGVDEA-GERSEISWRELPGRIGAVAAE TH_4609|M.thermoresistible__bu --SRLNWAQNLLRHRTSTAPAIVSVNED-GSESTLTWSELVSQVASLAAA Mb3691|M.bovis_AF2122/97 LNVAYNCVDRHVEAGHGDRVAIHWEGEPVGDRRTLTYSDLLAEVSKAANA Rv3667|M.tuberculosis_H37Rv LNVAYNCVDRHVEAGHGDRVAIHWEGEPVGDRRTLTYSDLLAEVSKAANA MMAR_5155|M.marinum_M LNVAYNCVDRHVEAGNGDRVAIHWVGEPIEDSRTLTYADLQAEVSKAANA MUL_4241|M.ulcerans_Agy99 LNVAYNCVDRHVEAGNGDRVAIHWVGEPIEDSRTLTYADLQAEVSKAANA MAV_0462|M.avium_104 LNVAYNCVDRHVQAGHGDRVAIHWEGESPGDQRSLTYSELYTQVCKAANA MLBr_00134|M.leprae_Br4923 TAAALVITNGSLRDRFQSSNVVEPAELLSDATRVEPSDYEPVSGDAYAFA . . .: . * Mflv_1473|M.gilvum_PYR-GCK LRAAGVESGDRVVGYLPNIPEAVVAFLATASIGAVWSACGQDYSAKAALD Mvan_5298|M.vanbaalenii_PYR-1 LRAAGIGPGDRVVGYLPNIPEAVIAFLATAAVGAVWSACGQDYSAKAALD MSMEG_6024|M.smegmatis_MC2_155 LVSLGVKPGDRVAGYLPNIPEAIIAFLATASIGAIWSGCGQDYTAKAALD MAB_4376c|M.abscessus_ATCC_199 LRRLGVGRGDCVAAYLPDVPDAMVAFLATASVGAVWAGCGQDYAPEGAAA TH_4609|M.thermoresistible__bu LRTMGVRPGDRVAAVLPNIAPTVVAVLATASVGAVWSCCSPDFGLQGLVS Mb3691|M.bovis_AF2122/97 LTDLGLVAGDRVAIYLPLIPEAVIAMLACARLGIMHSVVFGGFTAAALQA Rv3667|M.tuberculosis_H37Rv LTDLGLVAGDRVAIYLPLIPEAVIAMLACARLGIMHSVVFGGFTAAALQA MMAR_5155|M.marinum_M LTGLGLVAGDRVAIYLPLIPEAVIAMLACARLGIMHSVVFGGFTANALHA MUL_4241|M.ulcerans_Agy99 LTGLGLVAGDRVAIYLPLIPEAVIAMLACARLGIMHSVVFGGFTANTLHA MAV_0462|M.avium_104 LTDLGLVAGDRVAIYLPLIPEAVIAMLACARLGVMHSVVFAGFTAKALQA MLBr_00134|M.leprae_Br4923 TYTSGTTGKPKAAIHRHADPFTFVDAMCRKALRLTPQDIGLCSARMYFAY * .. . :.: :. : Mflv_1473|M.gilvum_PYR-GCK RLGQLEPKALVAADGYTYAGRYHDKRADVAALRSEIPSLTAIFTLD---- Mvan_5298|M.vanbaalenii_PYR-1 RLGQLEPKALVAADGYLFGGKYRDKRDDVRALAAGLPTLQATFSTD---- MSMEG_6024|M.smegmatis_MC2_155 RLGQLEPTVLVTADGYHFAGKTHDKADDIAALRDGLPTLKASVLVSRIGE MAB_4376c|M.abscessus_ATCC_199 RLAQLTPKVLISGRGYRYNGRWVSKQADTEVLHRLLPGEPALIIEL---- TH_4609|M.thermoresistible__bu RFAQIEPTVLIGTDGYRFNGRRVNRLELIEQLRAQLRTVRHTVVVRHLDR Mb3691|M.bovis_AF2122/97 RIVDAQAKLLITADGQFRRGKPSPLKAAADEALAAIPDCSVEHVLVVRRT Rv3667|M.tuberculosis_H37Rv RIVDAQAKLLITADGQFRRGKPSPLKAAADEALAAIPDCSVEHVLVVRRT MMAR_5155|M.marinum_M RIVDAQAKLLITSDGQFRRGHPAPLKDAADEAVSQ-PDSPVEHVLVVRRT MUL_4241|M.ulcerans_Agy99 RIVDAQAKLLITSDGQFRRGHPAPLKDAADEAVSQ-PDSPVEHVLVVRRT MAV_0462|M.avium_104 RIADAAAKLLITSDGQFRRGKPAPLKDAADEAVAD-PDSPVEHVVVVRRT MLBr_00134|M.leprae_Br4923 GLGNSVWFPLATGGSAVISSVPVSAESAAMLSTRFEPSVLYGVPSFFARV : : * . . Mflv_1473|M.gilvum_PYR-GCK -------------DL--AARVET-PLTPARVPFDHPLWVLFSSGTTGLPK Mvan_5298|M.vanbaalenii_PYR-1 -------------DL--AERSDN-ALDPVRVPFEHPLWILFSSGTTGLPK MSMEG_6024|M.smegmatis_MC2_155 ----ARPDWLDWAQL--SAPGPR-ELTTTAVDFDHPLWVLYSSGTTGLPK MAB_4376c|M.abscessus_ATCC_199 ------------------PTGSE-DPVVEMVPFDHPIWVLFSSGTTGKPK TH_4609|M.thermoresistible__bu ----KGENLPEAIEFGDLVTGDA-EPEYEQVAFDHPLWVLYSSGTTGSPK Mb3691|M.bovis_AF2122/97 GIEMAWSEGRDLWWHHVVGSASP-AHTPEPFDSEHPLFLLYTSGTTGKPK Rv3667|M.tuberculosis_H37Rv GIEMAWSEGRDLWWHHVVGSASP-AHTPEPFDSEHPLFLLYTSGTTGKPK MMAR_5155|M.marinum_M GIDVSWNDERDLWWHDVVDSASP-EHTPEPFDAEQPLFLLYTSGTTGKPK MUL_4241|M.ulcerans_Agy99 GIDVSWNDERDLWWHDVVDSASP-QHTPEPFDAEQPLFLLYTSGTTGKPK MAV_0462|M.avium_104 GIDVSWTDGRDLWWHDVVDAAAP-EHTPEPFPAEQPLFLLYTSGTTGKPK MLBr_00134|M.leprae_Br4923 VGACSPDSFRSLRCVVTAGEALEPALAERLVEFFGGIPILDGIGSSEVGQ . : :* *:: : Mflv_1473|M.gilvum_PYR-GCK GIVHGHG--------GVVVEHLKAVALQSDIGRD----DVFFWYTSPS-W Mvan_5298|M.vanbaalenii_PYR-1 GIMHGHG--------GVLLEHLKAVALQSDIGRD----DTFFWYTSPS-W MSMEG_6024|M.smegmatis_MC2_155 GIMHGHG--------GVLIEHLKAVALQNNIGPA----DTFFWYTSPS-W MAB_4376c|M.abscessus_ATCC_199 GIVHGHG--------GMLLEHLKGAGLHCDLGPG----DVFFWQTALS-W TH_4609|M.thermoresistible__bu GIVHSHG--------GILLESLKANGLHYDLGSA----DRVFIAASTA-W Mb3691|M.bovis_AF2122/97 GIMHTSG--------GYLTQCCYTMRTIFDVKPD----SDVFWCTADIGW Rv3667|M.tuberculosis_H37Rv GIMHTSG--------GYLTQCCYTMRTIFDVKPD----SDVFWCTADIGW MMAR_5155|M.marinum_M GIVHTSG--------GYLTQCCYTVHTIFDVKPE----TDVFWCTADIGW MUL_4241|M.ulcerans_Agy99 GIVHTSG--------GYLTQCCYTVHTIFDVKPE----TDVFWCTADIGW MAV_0462|M.avium_104 GIVHTSG--------GYLTQAAYTHYYVFDIKAD----TDVFWCTADIGW MLBr_00134|M.leprae_Br4923 TFVSNSVDDWRVGTLGKVLPPYEIRVVAPDGATAGSGIEGNLWVRGPS-- :: * : : : . Mflv_1473|M.gilvum_PYR-GCK MMWNFQ--VAGLLVGATIVCYDGSPTARHPETLWEIASRVGATVLGTSPG Mvan_5298|M.vanbaalenii_PYR-1 MMWNFQ--VAGLLVGATIVCYEGSPNAPQPDSLWGIAARIRATVLGTSPG MSMEG_6024|M.smegmatis_MC2_155 MMWNFQ--VAGLLVGATIVCYDGSPTYPKADALWDVSAKIGVTVLGTSPG MAB_4376c|M.abscessus_ATCC_199 MMWNFR--LAGLLVGATVVCYSGHPLYPNADRLWELLEAERVTYFGTSPG TH_4609|M.thermoresistible__bu VVWNML--VDAMVTGATVITYDGSPRAQGPGTLFRICADQRVTRFGTGAA Mb3691|M.bovis_AF2122/97 VTGHTYGVYGPLCNGVTEVLYEGTPDTPDRHRHFQIIEKYGVTIYYTAPT Rv3667|M.tuberculosis_H37Rv VTGHTYGVYGPLCNGVTEVLYEGTPDTPDRHRHFQIIEKYGVTIYYTAPT MMAR_5155|M.marinum_M VTGHTYGVYGPLANGITEVLYEGTPNTPDEHRHFQIIEKYGVTIYYTAPT MUL_4241|M.ulcerans_Agy99 VTGHTYGVYGPLANGITEVLYEGTPNTPDEHRHFQIIEEYGVTIYYTAPT MAV_0462|M.avium_104 VTGHTYGVYGPLANGVTEVLYEGTPDTPTQHRHFEIIEKYGVTIYYTAPT MLBr_00134|M.leprae_Br4923 IAQSYWNRPDSLLENGDWLNTRDRVRIDGDGWVTYGCRADDTEIVGGVNI : : . : . . Mflv_1473|M.gilvum_PYR-GCK YVLGCMKAEATPASTYDLSALRSVGITGS-ALPAASSLWLQDQVG---VQ Mvan_5298|M.vanbaalenii_PYR-1 YVLGCIKAEAEPGRTHDLSALRTVGITGS-SLPPSSSLWLRDHVG---VQ MSMEG_6024|M.smegmatis_MC2_155 YVLACSKAGAVPRKEHDLSALKVVGITGS-SLPPSSALWLRDNVGE-RVQ MAB_4376c|M.abscessus_ATCC_199 HLHASKKAGLEPSSEHDLAVLKTLGSSGS-PLSADLFQWAGAHTG---AT TH_4609|M.thermoresistible__bu YLIQCEKAGVNPATEYDLSALRSIMSTGS-PLPDSTFRWVYRDVAA-DVH Mb3691|M.bovis_AF2122/97 LIRMFMKWGREIPDSHDLSSLRLLGSVGE-PINPEAWRWYRDVIGGGRTP Rv3667|M.tuberculosis_H37Rv LIRMFMKWGREIPDSHDLSSLRLLGSVGE-PINPEAWRWYRDVIGGGRTP MMAR_5155|M.marinum_M LIRTFMKWGRAIPDAHDLSSLRLLGSVGE-PINPEAWRWYRDVVGAGHTP MUL_4241|M.ulcerans_Agy99 LIRTFMKWGRAIPDAHDLSSLRLLGSVGE-PINPEAWRWYRDVVGAGHTP MAV_0462|M.avium_104 LIRTFMKWGREIPDAHDLSSLRLLGSVGE-PINPEAWRWYRSVIGADRLP MLBr_00134|M.leprae_Br4923 NPREVERLIIEADAVAEAAVVGVREFTGASTLQAFLVPAVGAFIDESVMR : : : : * .: Mflv_1473|M.gilvum_PYR-GCK VASISGGTDVVSAFLGGVR-TVPVWPGELSAPYLGVALDAWDEDGQPVR- Mvan_5298|M.vanbaalenii_PYR-1 IASISGGTDVVSAFIGGVR-TVPVWPGELSAPYLGVALDAWDESGKPVR- MSMEG_6024|M.smegmatis_MC2_155 VSSISGGTDVVSAFIGGAP-TVPVWPGELSAPYLGAAIDAWDENGKSVR- MAB_4376c|M.abscessus_ATCC_199 VSSLSGGTDVCTAFAGGTP-EVPTHPGELPARYLGVDLHSWSPDRRSLI- TH_4609|M.thermoresistible__bu LGSDSGGTDVATAFVGANP-LQPVVAGAIQGPCLGVAVEAWNEAGQPVI- Mb3691|M.bovis_AF2122/97 LVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKIVDDHGDPLPP Rv3667|M.tuberculosis_H37Rv LVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKIVDDHGDPLPP MMAR_5155|M.marinum_M IVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKVVDDHGDPLAP MUL_4241|M.ulcerans_Agy99 IVDTWWQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKVVDDHGDPLAP MAV_0462|M.avium_104 IVDTWWQTETGATMISPLPGVAAAKPGSAMRPLPGISARIVDDHGDQLVP MLBr_00134|M.leprae_Br4923 DVHRRLLTQLTAFKVPHRFAIIERLPRSTNGKLLRNVLRAQSPTKPIWEL *: : . . Mflv_1473|M.gilvum_PYR-GCK ------GEVGELVITKPMPSMPVGFWNDRDGSRYRCAYFD------TYPG Mvan_5298|M.vanbaalenii_PYR-1 ------GEVGELVITKPMPSMPVGFWNDPDGKRYRSAYFE------TFPG MSMEG_6024|M.smegmatis_MC2_155 ------GEVGELVITKPLPSMPIAFWNDPDGSRYRAAYFE------MFPG MAB_4376c|M.abscessus_ATCC_199 ------GEVGEMVILQPMPCMPIRFWDDPDGSRYKAAYFEHEWADGQAPG TH_4609|M.thermoresistible__bu ------DQVGEMVITAPMPSMPIYFWADEDGSRYREAYFD------TYPG Mb3691|M.bovis_AF2122/97 HTEGAQHVTGYLVLDQPWPSMLRGIWGDP--ARYWHSYWS----KFSDKG Rv3667|M.tuberculosis_H37Rv HTEGAQHVTGYLVLDQPWPSMLRGIWGDP--ARYWHSYWS----KFSDKG MMAR_5155|M.marinum_M ETDEGTHVTGYLVLDQPWPSMLRGIWGDP--ARFHYAYWS----KFEDKG MUL_4241|M.ulcerans_Agy99 ETDEGTHVTGYLVLDQPWPSMLRGIWGDP--ARFHYAYWS----KFEDKG MAV_0462|M.avium_104 GIHHGEHVTGYLVLDQPWPSMLRGIWGDP--DRYVETYWS----RFAEQG MLBr_00134|M.leprae_Br4923 SLTESQSATKAQLDGRPASNAHAQAAVGHAAGATLKQRLS-------ALQ . : * . . . Mflv_1473|M.gilvum_PYR-GCK VWRHGDWITLTDRGSVVVHGRSDSTLNRHGIRMGSADIYQAVESLPEVAE Mvan_5298|M.vanbaalenii_PYR-1 VWRHGDWITITDHGSVIVHGRSDSTLNRHGIRMGSADIYQAVESLPEVTE MSMEG_6024|M.smegmatis_MC2_155 VWRHGDWITLTEHGSVVVHGRSDSTLNRHGIRMGSADIYQAVERIPEIVE MAB_4376c|M.abscessus_ATCC_199 VWRHGDWVTVTERGSLVIHGRSDATLNRNGIRMGSADIYEVVESMDQIAE TH_4609|M.thermoresistible__bu VWRHGDWITITTTGLCFVHGRSDSTINRGGVRMGSADIYAAVEALPEVAD Mb3691|M.bovis_AF2122/97 YYFAGDGARIDPDGAIWVLGRIDDVMNVSGHRISTAEVESALVAHSGVAE Rv3667|M.tuberculosis_H37Rv YYFAGDGARIDPDGAIWVLGRIDDVMNVSGHRISTAEVESALVAHSGVAE MMAR_5155|M.marinum_M YYFAGDGARLDSDGAIWVLGRIDDVMNVSGHRISTAEVESALVGHPGVAE MUL_4241|M.ulcerans_Agy99 YYFAGDGARLDSDGAIWVLGRIDDVMNVSGHRISTAEVESALVGHPGVAE MAV_0462|M.avium_104 WYFAGDSAYYDRDGAIWVVGRIDDVMNVSGHRLSTAEVESALVGHHGVAE MLBr_00134|M.leprae_Br4923 QERERLVVEAVCAEAVKMLGESDPGLINRDLAFSDLGFDSQMTVTLCNRL : *. * : . :. . : Mflv_1473|M.gilvum_PYR-GCK ALVIGAELPDGGYWMPLFVVPADGVKLDDGLRDKINERIRTELSP----- Mvan_5298|M.vanbaalenii_PYR-1 ALVIGAEQPDGGYWMPLFVVLADGVELTDEVRERINDIIRSEVSP----- MSMEG_6024|M.smegmatis_MC2_155 ALVIGAEQPDGGYWMPLFVVLADGVELTDELRDRIKSTIRTEVSP----- MAB_4376c|M.abscessus_ATCC_199 GFVLGVDGPNGAYWMPLFITMAPGHTFDDALGDQVAREIRDRLSP----- TH_4609|M.thermoresistible__bu SLVIGAELDDGEYYMPLFIVPTPGHALNSELEKRIRDTLRDNVSP----- Mb3691|M.bovis_AF2122/97 AAVVGVTDETTTQAICAFVVLRANYAPHDRTAEELRTEVARVISP----- Rv3667|M.tuberculosis_H37Rv AAVVGVTDETTTQAICAFVVLRANYAPHDRTAEELRTEVARVISP----- MMAR_5155|M.marinum_M AAVVGVVDDTTTQAICAFVVLRGNYEQHDGTSDELRAEVAEAISP----- MUL_4241|M.ulcerans_Agy99 AAVVGVVDDTTTQAICAFVVLRGNYEQHDGTSEELRAEVAEAISP----- MAV_0462|M.avium_104 AAVVGATDATTGQAICAFVVLCADYQVHDGIVDELRAEVAREISP----- MLBr_00134|M.leprae_Br4923 AVVTGLRLPETVGWDYGSISGLSRYLEAELSGVRSRPETPLSANSGAKGL . * * : . . .. Mflv_1473|M.gilvum_PYR-GCK -------RHVPDEIIAAPAIPHTRTGKKLEVPIKKLLQGGDPAKIVERSA Mvan_5298|M.vanbaalenii_PYR-1 -------RHVPDEIIRAPGVPHTRTGKKLEVPIKKLFQGGDPAKVVERSA MSMEG_6024|M.smegmatis_MC2_155 -------RHVPDEIIAAPGVPHTRTGKKLEVPIKKLFQGADPAKVVDRSA MAB_4376c|M.abscessus_ATCC_199 -------RHVPDEVIEAPGIPHTRTGKKLEVPICGVLAGRVDVSLDPR-S TH_4609|M.thermoresistible__bu -------RHVPDEIIEAPGVPMTRTGKRLEVPVKKLLQGVSPQSAVNRFT Mb3691|M.bovis_AF2122/97 -------IARPRDVHVVPELPKTRSGKIMRRLLRDVAENRE---LGDTST Rv3667|M.tuberculosis_H37Rv -------IARPRDVHVVPELPKTRSGKIMRRLLRDVAENRE---LGDTST MMAR_5155|M.marinum_M -------IARPREVHVVPELPKTRSGKIMRRLLRDIAEKRE---LGDTST MUL_4241|M.ulcerans_Agy99 -------IARPREVHVVPELPKTRSGKIMRRLLRDIAEKRE---LGDTST MAV_0462|M.avium_104 -------IAKPREVHVVPELPKTRSGKIMRRLLRDIAENRE---LGDTST MLBr_00134|M.leprae_Br4923 SPIDEELKKVEEMVVAIGASEKQRVADRLRALLGIIVDGEAGLSKRIQAA : * .. :. : : : Mflv_1473|M.gilvum_PYR-GCK VDDPALLDWYAGQCRAVTST--------- Mvan_5298|M.vanbaalenii_PYR-1 VDDPALLDWYVTQRRS------------- MSMEG_6024|M.smegmatis_MC2_155 VDNPDLLQWFVTQRRR------------- MAB_4376c|M.abscessus_ATCC_199 IDNPDLVDWYRERGRDHRW---------- TH_4609|M.thermoresistible__bu VADPDILDWYLRFAEEFRRTTGRRGSCAR Mb3691|M.bovis_AF2122/97 LLDPTVFDAIR-AAK-------------- Rv3667|M.tuberculosis_H37Rv LLDPTVFDAIR-AAK-------------- MMAR_5155|M.marinum_M LLDPTVFDAIRNAAK-------------- MUL_4241|M.ulcerans_Agy99 LLDPTVFDAIRNAAK-------------- MAV_0462|M.avium_104 LLDPGVFDAIR-AAK-------------- MLBr_00134|M.leprae_Br4923 STPDEIFQLIDSELCE------------- :.: