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VEASPVRPAAMPSTRRQHEQYKRMLDAAEELAMTRELDHVQMHDVAKHANVAIGTLYRYFPTKRHLFVSA LVRESERLVGRLPSLPDGGQAAADRVADALVRALRGLTRRRMLAIAMIRSSNSASLAEVPDLMQIEKRFH ELISEVAGLSDPTDDDEAVIRLLVHQWFGCIQVCLNGGLTVAQAEADLRRASRLLMRDWPSVSS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4201c | - | - | 100% (205) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0579c | - | 5e-19 | 32.60% (181) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3650 | - | 5e-09 | 26.24% (202) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3605 | - | 4e-20 | 31.89% (185) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_1459 | - | 2e-18 | 32.24% (183) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3574 | - | 4e-20 | 31.89% (185) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | MLBr_02568 | - | 3e-06 | 27.91% (129) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_5069 | - | 2e-19 | 31.87% (182) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0584 | - | 4e-19 | 31.67% (180) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6042 | - | 3e-18 | 31.11% (180) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1745 | - | 3e-19 | 31.32% (182) | TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) |
| M. ulcerans Agy99 | MUL_4145 | - | 2e-19 | 31.87% (182) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5312 | - | 1e-18 | 32.24% (183) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3605|M.bovis_AF2122/97 ---------------------------------------------MAVLA
Rv3574|M.tuberculosis_H37Rv ---------------------------------------------MAVLA
MMAR_5069|M.marinum_M ---------------------------------------------MAVLA
MUL_4145|M.ulcerans_Agy99 ---------------------------------------------MAVLA
MAV_0584|M.avium_104 ---------------------------------------------MAVLA
Mflv_1459|M.gilvum_PYR-GCK ------------MSGSSESAT------------AGSDSRPRQVMNVAVLA
Mvan_5312|M.vanbaalenii_PYR-1 ------------MSGTSEFAADKSQTSARATSGAGSESRPRQVMNVAVLA
MSMEG_6042|M.smegmatis_MC2_155 ------------------------------------------MTNVAVLS
TH_1745|M.thermoresistible__bu MSSSTGTNPGRGSDSTGSETNGAAATGAGSGSTGTSRTRGRQVTNVAVLT
MAB_4201c|M.abscessus_ATCC_199 -----------------------------------------MVEASPVRP
MLBr_02568|M.leprae_Br4923 -----------------------------------------------MAG
:
Mb3605|M.bovis_AF2122/97 ESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYR
Rv3574|M.tuberculosis_H37Rv ESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYR
MMAR_5069|M.marinum_M ESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYR
MUL_4145|M.ulcerans_Agy99 ESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYR
MAV_0584|M.avium_104 ESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYR
Mflv_1459|M.gilvum_PYR-GCK ESELGSEAQRERRKRILDATLAIASKGGYEAVQMRAVAERADVAVGTLYR
Mvan_5312|M.vanbaalenii_PYR-1 ESELGSEAQRERRKRILDATLAIASKGGYEAVQMRAVAERADVAVGTLYR
MSMEG_6042|M.smegmatis_MC2_155 ESELGSEAQRERRKRILDATLAIASKGGYEAVQMRAVAERADVAVGTLYR
TH_1745|M.thermoresistible__bu DSELGSEAQRERRKRILDATLAIASKGGYEAVQMRAVAERADVAVGTLYR
MAB_4201c|M.abscessus_ATCC_199 AAMPSTRRQHEQYKRMLDAAEELAMTRELDHVQMHDVAKHANVAIGTLYR
MLBr_02568|M.leprae_Br4923 GAKRIPRAVREQ--QMLDAAVQMFSVNGYHKTSMDAIAAEAQISKPMLYL
: .. :*: ::***: : . ..* :* .*::: **
Mb3605|M.bovis_AF2122/97 YFPSKVHLLVSALGREFSRIDAKTDRSAVAGA-TPFQRLNFMVGKLNRAM
Rv3574|M.tuberculosis_H37Rv YFPSKVHLLVSALGREFSRIDAKTDRSAVAGA-TPFQRLNFMVGKLNRAM
MMAR_5069|M.marinum_M YFPSKVHLLVSALGREFSRIDAKTDRSAMTGG-TPFQRLNFMVGKLNRAM
MUL_4145|M.ulcerans_Agy99 YFPSKVHLLVSALGREFSRIDAKTDRSAMTGG-TPFQRLNFMVGKLNRAM
MAV_0584|M.avium_104 YFPSKVHLLVSALGREFSRIDAKTDRAALTGG-TPFQRLNFMVGKLNRAM
Mflv_1459|M.gilvum_PYR-GCK YFPSKVHLLVSALGREFERIDAKTDRAALAAGATAYQRLNIMVGKLNRAM
Mvan_5312|M.vanbaalenii_PYR-1 YFPSKVHLLVSALGREFERIDAKTDRSAFPAGATAYQRLNIMVGKLNRAM
MSMEG_6042|M.smegmatis_MC2_155 YFPSKVHLLVSALGREFERIDAKTDRAALAGG-TPYQRLNFMVGKLNRAM
TH_1745|M.thermoresistible__bu YFPSKVHLLVSALGREFERIDAKTDRSTLVGD-TPYERLNFMVSRLNRAM
MAB_4201c|M.abscessus_ATCC_199 YFPTKRHLFVSALVRESERLVGRLP-SLPDGGQAAADRVADALVRALRGL
MLBr_02568|M.leprae_Br4923 YYGSKEDLFGACLNREMSRFIAMVRADIDFTQ-SPKDLLRNTIVSFLRYI
*: :* .*: :.* ** .*: . :. : : : * :
Mb3605|M.bovis_AF2122/97 QRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMANGEPTEDQY
Rv3574|M.tuberculosis_H37Rv QRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMANGEPTEDQY
MMAR_5069|M.marinum_M QRNPLLTEAMTRAYVFADASAATEVDQVEKLIDSMFARAMADGEPTEDQY
MUL_4145|M.ulcerans_Agy99 QRNPLLTEAMTRAYVFADASAATEVDQVEKLIDSMFARAMADGEPTEDQY
MAV_0584|M.avium_104 QRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMADGEPTEDQY
Mflv_1459|M.gilvum_PYR-GCK QRNPLLTEAMTRAFVFADASAAGEVDHVGKLMDSMFARAMSDGEPTEDQY
Mvan_5312|M.vanbaalenii_PYR-1 QRNPLLTEAMTRAFVFADASAAGEVDHVGKLMDSMFARAMSDGEPTEDQY
MSMEG_6042|M.smegmatis_MC2_155 QRNPLLTEAMTRAFVFADASAAGEVDHVGKLMDSMFARAMSDGEPTEDQY
TH_1745|M.thermoresistible__bu QRNPLLTEAMTRAFVFADASAAGEVDHVGRLMDSMFARAMADGEPTEDQY
MAB_4201c|M.abscessus_ATCC_199 TRRRMLAIAMIRSSNSASLAEVPDLMQIEKRFHELISEVAGLSDPTDDDE
MLBr_02568|M.leprae_Br4923 DANRASWIVMY-IQAMSLPAFAQTVREARDQITELVAGLMRVGTRSSRPD
. .* : : . : . : .:.: . :.
Mb3605|M.bovis_AF2122/97 HIARVISDVWLSNLLAWLTRRAS-ATDVSKRLDLAVRLLIGDQDSA----
Rv3574|M.tuberculosis_H37Rv HIARVISDVWLSNLLAWLTRRAS-ATDVSKRLDLAVRLLIGDQDSA----
MMAR_5069|M.marinum_M HIARVISDVWLSNLLAWLTRRAS-ATDVSKRLDLAVRLLIGDQEATA---
MUL_4145|M.ulcerans_Agy99 HIARVISDVWLSNLLAWLTRRAS-ATDVSKRLDLAVRLLIGDQEATA---
MAV_0584|M.avium_104 HIARVISDVWLSNLLAWLTRRAS-ATDVSKRLDLAVRLLLGEHG------
Mflv_1459|M.gilvum_PYR-GCK HIARVISDVWLSNLLAWLTRRAS-ATDVAKRLDLAVRLLIGDGDQPKI--
Mvan_5312|M.vanbaalenii_PYR-1 HIARVISDVWLSNLLAWLTRRAS-ATDVAKRLDLAVRLLIGDGDQPKI--
MSMEG_6042|M.smegmatis_MC2_155 HIARVISDVWLSNLLAWLTRRAS-ATDVSKRLDLAVRLLIGTEEQPKI--
TH_1745|M.thermoresistible__bu HIARVISDVWLSNLLAWLTRRAS-ATDVSKRLELAVRLLVGDGKNPKV--
MAB_4201c|M.abscessus_ATCC_199 AVIRLLVHQWFGCIQVCLNGGLT-VAQAEADLRRASRLLMRDWPSVSS--
MLBr_02568|M.leprae_Br4923 HEYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMINLFWHGLKGAPADR
.:: .. . . : . .*:
Mb3605|M.bovis_AF2122/97 ---------
Rv3574|M.tuberculosis_H37Rv ---------
MMAR_5069|M.marinum_M ---------
MUL_4145|M.ulcerans_Agy99 ---------
MAV_0584|M.avium_104 ---------
Mflv_1459|M.gilvum_PYR-GCK ---------
Mvan_5312|M.vanbaalenii_PYR-1 ---------
MSMEG_6042|M.smegmatis_MC2_155 ---------
TH_1745|M.thermoresistible__bu ---------
MAB_4201c|M.abscessus_ATCC_199 ---------
MLBr_02568|M.leprae_Br4923 DFGPSIVAG