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MTSQHERAVTFAALHQSGTFVVPNPWDAGTARILTAYGFPALATTSAGLAFALGRRDSANLIGQAETLAN AAQIAAATHLPVSADLENGGPTIGDIAMTIREAAASGLVGGSIEDATGRPDAPIFPLAEAVDRITAAAHT TRDLPFPFTLTARAENFLYGRPDLTDTITRLNAYAEAGADVVYAPGLPDAEAVRTVCAAVDRPVNLLATG FVLNHSVGEIAEWGVRRISLGSAMARAALGAFVGGARELAQQGTFGFATHALSYGDANALFPPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4079 | - | - | 100% (274) | carboxyvinyl-carboxyphosphonate phosphorylmutase |
| M. abscessus ATCC 19977 | MAB_4410c | - | 8e-17 | 30.51% (236) | PEP phosphonomutase and related enzymes |
| M. abscessus ATCC 19977 | MAB_4618 | - | 2e-11 | 27.63% (257) | carboxyvinyl-carboxyphosphonate phosphorylmutase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2021c | - | 2e-16 | 31.56% (244) | hypothetical protein Mb2021c |
| M. gilvum PYR-GCK | Mflv_0391 | - | 3e-15 | 30.00% (230) | hypothetical protein Mflv_0391 |
| M. tuberculosis H37Rv | Rv1998c | - | 1e-16 | 31.17% (247) | hypothetical protein Rv1998c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0514 | - | 4e-21 | 32.92% (240) | PEP phosphonomutase |
| M. avium 104 | MAV_0345 | prpB | 4e-15 | 28.96% (259) | methylisocitrate lyase |
| M. smegmatis MC2 155 | MSMEG_4393 | - | 8e-19 | 34.29% (210) | carboxyvinyl-carboxyphosphonate phosphorylmutase |
| M. thermoresistible (build 8) | TH_1918 | - | 6e-20 | 32.38% (244) | transferase |
| M. ulcerans Agy99 | MUL_1177 | - | 1e-16 | 31.63% (215) | PEP phosphonomutase |
| M. vanbaalenii PYR-1 | Mvan_0289 | - | 1e-17 | 31.76% (233) | hypothetical protein Mvan_0289 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0391|M.gilvum_PYR-GCK ----MARTEDLKARAEALLALHQPGNPVILPTVWDAWSAHLAVDAGFSAL
Mvan_0289|M.vanbaalenii_PYR-1 -----MTNDVLKARAEALLALHQPGNPVILPTVWDAWSAKLATDAGFAAL
TH_1918|M.thermoresistible__bu ----------LQKRASDFLALHRPGDPVVLPTVWDAWSARLAVDAGFPAL
MMAR_0514|M.marinum_M -MPSEQGLNVTAERALALLALHQPGNPVVLPTVWDAWSARLAANAGFAAL
MUL_1177|M.ulcerans_Agy99 ----------------------------MLSTVWDAWSARLAANAGFAAL
Mb2021c|M.bovis_AF2122/97 ---------------MSFHDLHHQGVPFVLPNAWDVPSALAYLAEGFTAI
Rv1998c|M.tuberculosis_H37Rv ---------------MSFHDLHHQGVPFVLPNAWDVPSALAYLAEGFTAI
MAB_4079|M.abscessus_ATCC_1997 -------MTSQHERAVTFAALHQSG-TFVVPNPWDAGTARILTAYGFPAL
MSMEG_4393|M.smegmatis_MC2_155 --------MDIHSLRSTFAERLHAGGNIVAPGAYDALSAQIIARSGFEAV
MAV_0345|M.avium_104 MRDMIGAARSPEQKRAQLRAALESGRLQRFPGAFSPLVAKLVAELGFDGV
. :. * ** .:
Mflv_0391|M.gilvum_PYR-GCK TVGSHPLADSIGKPDNEGMT-FDDVLTRVAQITAAVDVPLSVDIESG--Y
Mvan_0289|M.vanbaalenii_PYR-1 TVGSHPLADSVGKSDREGMT-FDDVLTRVAQITAAVDVPLSVDIESG--Y
TH_1918|M.thermoresistible__bu TVGSHPVADSLGKADNEGMT-FDDVLTRVGQITAAVEVPVSVDIESG--Y
MMAR_0514|M.marinum_M TVGSHPLADSIGKPDNEGMS-FDDVLARVTQITAAVDIPVSVDIESG--Y
MUL_1177|M.ulcerans_Agy99 TVGSHPLADSIGKPDNEGMS-FDDVLARVAQITAAVDIPVSVDIESG--Y
Mb2021c|M.bovis_AF2122/97 GTTSFGVSSSGGHPDGHRAT-RGANIA-LAAALAPLQCYVSVDIEDG--Y
Rv1998c|M.tuberculosis_H37Rv GTTSFGVSSSGGHPDGHRAT-RGANIA-LAAALAPLQCYVSVDIEDG--Y
MAB_4079|M.abscessus_ATCC_1997 ATTSAGLAFALGRRDSANLIGQAETLANAAQIAAATHLPVSADLENGGPT
MSMEG_4393|M.smegmatis_MC2_155 FIGSFGIAASAYGLPDTGLLSLDQLTEHTRNTARAVDIPVIADAEGGFFE
MAV_0345|M.avium_104 YVSGAALSADLG-LPDIGLTTLTEVSGRGAQIAAVTELPTLIDADTGFGE
. :: . * : *
Mflv_0391|M.gilvum_PYR-GCK AEEPGRLIDGLLSVDAVGLNIEDTVHSEGGRLRS--SGEHAALVGGLRAA
Mvan_0289|M.vanbaalenii_PYR-1 AEAPTRLIEGLLSVGAVGLNIEDTVHSEGGRLRS--SSEHAQLVGALRAA
TH_1918|M.thermoresistible__bu AESPERLITGLLDAGAVGLNIEDTVHSEGRRLRS--VAEHAELVGALRAA
MMAR_0514|M.marinum_M GLDAQRLIEGLLSVGAVGLNIEDTVHSEGARLRS--RREHAELVGALRSA
MUL_1177|M.ulcerans_Agy99 GLDAQRLIEGLLNVGAVGLNIEDTVHSEGARLRS--RREHAELVGALRSA
Mb2021c|M.bovis_AF2122/97 SDEPDAIADYVAQLSTAGINIEDSSAEK---------LIDPALAAAKIVA
Rv1998c|M.tuberculosis_H37Rv SDEPDAIADYVAQLSTAGINIEDSSAEK---------LIDPALAAAKIVA
MAB_4079|M.abscessus_ATCC_1997 IGDIAMTIREAAASGLVGGSIEDATGRPDAPIFP--LAEAVDRITAAAHT
MSMEG_4393|M.smegmatis_MC2_155 PANMWRTVREFEDAGVCAIHIEDNLGGKHSAEPA--GLLSPEAMSARIRA
MAV_0345|M.avium_104 PLNAARTVTMLEYAGLAGCHLEDQVNPKRCGHLDGKAVVPVDEMVRRLRA
. . :** :
Mflv_0391|M.gilvum_PYR-GCK ADAAGVH--VVVNARTD-LFLRQDGDEADRVDRAIARLKEAADAGADVLY
Mvan_0289|M.vanbaalenii_PYR-1 ADAAGVH--VVVNARTD-LFLRQDGDESDRVDRAIARLKEAAAAGADVLY
TH_1918|M.thermoresistible__bu ADAAGVH--VVVNARTD-LFLRQDGDESDRVDRAIARLTECARAGADVLY
MMAR_0514|M.marinum_M ADAAGVH--VVLNARTD-LFLRRDGDPADRFERAVARLTEAAAAGADVLY
MUL_1177|M.ulcerans_Agy99 ADAAGVH--VVLNARTD-LFLRRDGDPADRFERAVAWLTEAAAAGADVLY
Mb2021c|M.bovis_AF2122/97 IKQRNPE--VFVNARVDTYWLRQHADTTSTIQRALR----YVDAGADGVF
Rv1998c|M.tuberculosis_H37Rv IKQRNPE--VFVNARVDTYWLRQHADTTSTIQRALR----YVDAGADGVF
MAB_4079|M.abscessus_ATCC_1997 TRDLPFP--FTLTARAENFLYGR-----PDLTDTITRLNAYAEAGADVVY
MSMEG_4393|M.smegmatis_MC2_155 AADAKTDPAFQIIARTDARWVYG------DVKETVRRLRAYIDAGADMVF
MAV_0345|M.avium_104 AVSARRDPNFVVCARTDAAAIEG-------LPAAIERARAYADAGADLIF
. : **.: . :: **** ::
Mflv_0391|M.gilvum_PYR-GCK PVGVHPPEVMRRLTSELPLPVNAIARPDQSDPAS----------------
Mvan_0289|M.vanbaalenii_PYR-1 PVGVHPPEVMRRLTSELPLPVNAIARPESADPAS----------------
TH_1918|M.thermoresistible__bu PVGRHDPDILRRLATELPLPVNAIAAPDQADPAS----------------
MMAR_0514|M.marinum_M PVGRHDPDTLRRLAAQLPLPINAIALPDQDDPAS----------------
MUL_1177|M.ulcerans_Agy99 PVGRHDPDTLRRLAAQLPLPINAIALPDQDDPAS----------------
Mb2021c|M.bovis_AF2122/97 VPLANDPDELAELTRNIPCPVNTLPVPG-LTIAD----------------
Rv1998c|M.tuberculosis_H37Rv VPLANDPDELAELTRNIPCPVNTLPVPG-LTIAD----------------
MAB_4079|M.abscessus_ATCC_1997 APGLPDAEAVRTVCAAVDRPVNLLATGFVLNHSVGE--------------
MSMEG_4393|M.smegmatis_MC2_155 APGIS-AAELAAVRADLARPVMVLADLPTRAGEALPEDSVDDFVAAGANL
MAV_0345|M.avium_104 TEALQCPTEFERFRAALDTPLLANMTEFGKSPLLGADRLADIG-------
. . . : *:
Mflv_0391|M.gilvum_PYR-GCK ----YGPLGVARISFG------PFWQAALAERSK-------------ELL
Mvan_0289|M.vanbaalenii_PYR-1 ----YGPLGVARISFG------PFWQAALAERAR-------------EIL
TH_1918|M.thermoresistible__bu ----FGPLGVARISFG------PFFQAALAVRAG-------------EIL
MMAR_0514|M.marinum_M ----FGRLGVARISFG------PFLQAALSGRAT-------------ELL
MUL_1177|M.ulcerans_Agy99 ----FGRLGVARISVG------PFLQAGLSGRAT-------------ELL
Mb2021c|M.bovis_AF2122/97 ----LGELGVARVSTGSVPYSAGLYAAAHAARAVRDGEQLPRSVPYAELQ
Rv1998c|M.tuberculosis_H37Rv ----LGELGVARVSTGSVPYSAGLYAAAHAARAVSDGEQLPRSVPYAELQ
MAB_4079|M.abscessus_ATCC_1997 ----IAEWGVRRISLG-----SAMARAALGAFVGGARELAQQGTFGFATH
MSMEG_4393|M.smegmatis_MC2_155 IVLFYLTLGAAALGVR------RVLEELTEYRDVRKLDGLFESQHAFEAA
MAV_0345|M.avium_104 YNVVIYPVTTLRLAMHAVEAGLREIADTGTQSGLLDRMQHRSRLYQLLRY
. :.
Mflv_0391|M.gilvum_PYR-GCK ARWR------------
Mvan_0289|M.vanbaalenii_PYR-1 ARWI------------
TH_1918|M.thermoresistible__bu ARWR------------
MMAR_0514|M.marinum_M ARWR------------
MUL_1177|M.ulcerans_Agy99 ARWR------------
Mb2021c|M.bovis_AF2122/97 ARLVDYENRTSTT---
Rv1998c|M.tuberculosis_H37Rv ARLVDYENRTSTT---
MAB_4079|M.abscessus_ATCC_1997 ALSYGDANALFPPG--
MSMEG_4393|M.smegmatis_MC2_155 MGYDTYEARVARYGGR
MAV_0345|M.avium_104 ADYNHFDSDIYNFPR-