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VGRASHAESSCTLARPLGEIGDGWSLLIVRDAFDGLRRFGEFQKSLGLAKNILASRLSTLVENGILEVVP AGARHEYQLTEKGRGLFPVLVALRQWSGEFCFRPGEPRVSLIDRKTSSPVRRFELRAADGRLLAPEDTTV AQTAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4063c | - | - | 100% (146) | HxlR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3456 | - | 5e-14 | 35.92% (103) | HxlR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4427c | - | 2e-11 | 31.03% (116) | putative transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3122 | - | 2e-21 | 43.86% (114) | putative transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1806 | - | 2e-13 | 37.84% (111) | HxlR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3095 | - | 2e-21 | 43.86% (114) | putative transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1555 | - | 4e-17 | 39.09% (110) | transcriptional regulatory protein |
| M. avium 104 | MAV_4183 | - | 3e-13 | 30.88% (136) | putative transcriptional regulator family protein |
| M. smegmatis MC2 155 | MSMEG_6580 | - | 2e-20 | 40.48% (126) | transcriptional regulator family protein |
| M. thermoresistible (build 8) | TH_2405 | - | 6e-09 | 36.67% (90) | putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_3475 | - | 3e-17 | 39.09% (110) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4941 | - | 3e-12 | 35.71% (98) | HxlR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3122|M.bovis_AF2122/97 -------MAVSDLSHRFEGESVGRALELVGERWTLLILREAFFGVRRFGQ
Rv3095|M.tuberculosis_H37Rv -------MAVSDLSHRFEGESVGRALELVGERWTLLILREAFFGVRRFGQ
MMAR_1555|M.marinum_M -------MGAADLSHRFEGESVGRALELVGERWTLLILREAFFGVQRFGQ
MUL_3475|M.ulcerans_Agy99 -------MGAADLSHRFEGESVGRALELVGERWTLLILREAFFGVQRFGQ
MAV_4183|M.avium_104 MTLLQGPLADRDAWSAVGECAIEKTMAVVGTKSAMLIMREAYYGTTRFDD
MSMEG_6580|M.smegmatis_MC2_155 --------MGRKNVESL-DCSVARSLAVLGERWTILILREALLGTRRFAD
MAB_4063c|M.abscessus_ATCC_199 --------MVGRASHAESSCTLARPLGEIGDGWSLLIVRDAFDGLRRFGE
Mflv_1806|M.gilvum_PYR-GCK ------------------------MLGLLGDEWTLLIVQRALLGARRYGE
Mvan_4941|M.vanbaalenii_PYR-1 --------------MAGTPNAVARMLSLLGDEWTLLIVQRALLGARRYGD
TH_2405|M.thermoresistible__bu ----------MASRTYGQHCALAKSLDLVGDRWTLLIVRELLDGPRRYSD
: :* ::**:: * *: :
Mb3122|M.bovis_AF2122/97 LARNLG-IPRPTLSSRLRMLVEVGLFDRVPYSS--DPERHEYRLTEAGRD
Rv3095|M.tuberculosis_H37Rv LARNLG-IPRPTLSSRLRMLVEVGLFDRVPYSS--DPERHEYRLTEAGRD
MMAR_1555|M.marinum_M LARNLN-IPRPTLSSRLRMLVNAGLLDRVPYSQ--DPERHEYRLTDTGHE
MUL_3475|M.ulcerans_Agy99 LARNLN-IPRPTLSSRLRMLVNAGLLDRVPYSQ--DPERHEYRLTDTGHE
MAV_4183|M.avium_104 FARRVG-ITKAATSARLAELVELGLLKRRPYREPGQRSRDEYVLTQAGID
MSMEG_6580|M.smegmatis_MC2_155 FQSRLG-IGADMLSDRLSTLVEYGVLTKQPYQEPGQRPRAEYLLTPAGRE
MAB_4063c|M.abscessus_ATCC_199 FQKSLG-LAKNILASRLSTLVENGILEVVPAG-----ARHEYQLTEKGRG
Mflv_1806|M.gilvum_PYR-GCK FLDALP-VSNAVLTSRLQSLSATEMLSRNQYQS--NPPRFEYLVTPMSRS
Mvan_4941|M.vanbaalenii_PYR-1 FAAALP-VSNTVLSGRLQSLTADGLLIRSQYQS--NPPRSEYLPTSMGRS
TH_2405|M.thermoresistible__bu LLTALRPIATDMLATRLRHLEEHHLVRRRELPKP--ASGTVYELTADGAA
: : : : ** * :. * * .
Mb3122|M.bovis_AF2122/97 LFAAIVVLMQWGDEYLPRPEG---------PPIKLRHHTCGEHADPRLIC
Rv3095|M.tuberculosis_H37Rv LFAAIVVLMQWGDEYLPRPEG---------PPIKLRHHTCGEHADPRLIC
MMAR_1555|M.marinum_M LFAAIVVLMQWGDKHLPNPDG---------PPIVLRHH-CGQFVEPRLIC
MUL_3475|M.ulcerans_Agy99 LFAAIVVLMQWGDKHLPNPDG---------PPIVLRHH-CGQFVEPRLIC
MAV_4183|M.avium_104 FMPVVWAMFEWGRRHLPGRHR---------LQLTHLGCGAEVGVE---IR
MSMEG_6580|M.smegmatis_MC2_155 LHVLVAALQQWGDRHLPRPAG---------PTMTRKARRTDRPVR---VA
MAB_4063c|M.abscessus_ATCC_199 LFPVLVALRQWSGEFCFRPGE---------PRVSLIDRKTSSPVRRFELR
Mflv_1806|M.gilvum_PYR-GCK LWPMLTSIWEWERRWVTDHAE---------PLPRMRHTGCGHEFAPRVVC
Mvan_4941|M.vanbaalenii_PYR-1 LWPMLTSIWEWERRWVPEHAE---------PLPRMHHATCGRPFQPVVTC
TH_2405|M.thermoresistible__bu LEAVVHAFIRWGRSLLETRRAGDVVRPHWLARAVRAHVRPDRTGPPLSVR
: : : .*
Mb3122|M.bovis_AF2122/97 THCGEEITARNVTPEPGPGFKAKLASS-----------------------
Rv3095|M.tuberculosis_H37Rv THCGEEITARNVTPEPGPGFKAKLASS-----------------------
MMAR_1555|M.marinum_M AHCGEEITARNVTPEAGPGFGDAVAAPN----------------------
MUL_3475|M.ulcerans_Agy99 AHCGEEITARNVTPEAGPGYGDAVAAPN----------------------
MAV_4183|M.avium_104 CAEGHLVPPDELGMRLAKKSG-----------------------------
MSMEG_6580|M.smegmatis_MC2_155 FID-DLGDEVPINDVVSIPTGN----------------------------
MAB_4063c|M.abscessus_ATCC_199 AADGRLLAPEDT--TVAQTAG-----------------------------
Mflv_1806|M.gilvum_PYR-GCK RSCTAEASGNDVVAQWGPSGSWQRSIPGGTQRRRSSGHRSGAAILFPQTM
Mvan_4941|M.vanbaalenii_PYR-1 RACDGPASGKDVAAQWGPSGSWERSIPSGTNRRRSSGRRSGAALLFPQTM
TH_2405|M.thermoresistible__bu LVTPEGAAAVRISADAVEDLDDDTAVDVTLTGAAEVLAAALHPDRAAELV
Mb3122|M.bovis_AF2122/97 --------------------------------------------------
Rv3095|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1555|M.marinum_M --------------------------------------------------
MUL_3475|M.ulcerans_Agy99 --------------------------------------------------
MAV_4183|M.avium_104 --------------------------------------------------
MSMEG_6580|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4063c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1806|M.gilvum_PYR-GCK SVIGDRWAFAMLVAAFVGMRRFTDFQAQLGAPPTTVADRLTTFTDEGILV
Mvan_4941|M.vanbaalenii_PYR-1 SVVGDRWAFALLVAAFVGVGRFTDFQAQLGAPPATIADRLSVFTDENILG
TH_2405|M.thermoresistible__bu AQG--RLRVDGRADALRRLAEVVTAPAGRAVPDRS---------------
Mb3122|M.bovis_AF2122/97 --------------------------------------------------
Rv3095|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1555|M.marinum_M --------------------------------------------------
MUL_3475|M.ulcerans_Agy99 --------------------------------------------------
MAV_4183|M.avium_104 --------------------------------------------------
MSMEG_6580|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4063c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1806|M.gilvum_PYR-GCK SGDGGYQFTDKGRAFFPVLVCALSWAQRWFPSPEGPAVILTHTACGRRFD
Mvan_4941|M.vanbaalenii_PYR-1 QSGGRYGLTEKGLAFFPVLVCALAWAQRWLPSPEGPAVLLTHTACDRRFA
TH_2405|M.thermoresistible__bu --------------------------------------------------
Mb3122|M.bovis_AF2122/97 ---------------------
Rv3095|M.tuberculosis_H37Rv ---------------------
MMAR_1555|M.marinum_M ---------------------
MUL_3475|M.ulcerans_Agy99 ---------------------
MAV_4183|M.avium_104 ---------------------
MSMEG_6580|M.smegmatis_MC2_155 ---------------------
MAB_4063c|M.abscessus_ATCC_199 ---------------------
Mflv_1806|M.gilvum_PYR-GCK PVLRCDQCQRHLRGAQIRPVP
Mvan_4941|M.vanbaalenii_PYR-1 PVLVCDQCGNRLRAEQVLPVS
TH_2405|M.thermoresistible__bu ---------------------