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AVHAHPDDESSRGAATLAKYAAEGHQVLVVTATGGERGDILNPAMNRAGVQENLRQVRRQEMALAAKTLG VEHHWLGFTDSGLQLDPGLLPADGFALVPLAESVACLTAVIEQFRPHVMVTYNECGGYPHPDHIRCHQMA VAAYGACPDVAKLYYFHEIVRVTPRMVRFAGRAERIVSRMPRRQSAAAASTDQRLGDVTVPGWVRVSSML TRRVGSRRATTLVACGDYFCVRDRALRAHASQVDPNGPFFLVPWTWRQHLWPTEKFELAHSRVATKAPET DLFAGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4015c | - | - | 100% (287) | hypothetical protein MAB_4015c |
| M. abscessus ATCC 19977 | MAB_1203 | - | 6e-76 | 50.00% (308) | LmbE-like protein |
| M. abscessus ATCC 19977 | MAB_1316 | - | 9e-26 | 43.90% (164) | putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1111 | mca | 4e-78 | 52.82% (301) | Mycothiol conjugate amidase Mca (Mycothiol S-conjugate |
| M. gilvum PYR-GCK | Mflv_2050 | - | 1e-72 | 50.17% (301) | LmbE family protein |
| M. tuberculosis H37Rv | Rv1082 | mca | 4e-78 | 52.82% (301) | Mycothiol conjugate amidase Mca (Mycothiol S-conjugate |
| M. leprae Br4923 | MLBr_02391 | - | 6e-76 | 51.49% (303) | hypothetical protein MLBr_02391 |
| M. marinum M | MMAR_4385 | mca | 3e-76 | 50.50% (301) | mycothiol conjugate amidase Mca |
| M. avium 104 | MAV_1206 | - | 4e-76 | 51.16% (301) | mycothiol conjugate amidase Mca |
| M. smegmatis MC2 155 | MSMEG_5261 | - | 6e-76 | 52.49% (301) | mycothiol conjugate amidase Mca |
| M. thermoresistible (build 8) | TH_2167 | - | 2e-74 | 51.16% (301) | mycothiol conjugate amidase Mca |
| M. ulcerans Agy99 | MUL_0198 | mca | 2e-76 | 50.50% (301) | mycothiol conjugate amidase Mca |
| M. vanbaalenii PYR-1 | Mvan_4667 | - | 4e-72 | 49.50% (301) | LmbE family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4385|M.marinum_M MSKLRLMAVHAHPDDESSKGAATLARYADEGHRVLVVTLTGGERGEILNP
MUL_0198|M.ulcerans_Agy99 MSKLRLMAVHAHPDDESSKGAATLARYADEGHRVLVVTLTGGERGEILNP
Mb1111|M.bovis_AF2122/97 MSELRLMAVHAHPDDESSKGAATLARYADEGHRVLVVTLTGGERGEILNP
Rv1082|M.tuberculosis_H37Rv MSELRLMAVHAHPDDESSKGAATLARYADEGHRVLVVTLTGGERGEILNP
MLBr_02391|M.leprae_Br4923 MSELRLMAVHAHPDDESSKGAATLARYADEGHRVLVVTLTGGERGEILNP
MAV_1206|M.avium_104 MSELRLMAVHAHPDDESSKGAATLARYADEGHRVLVVTLTGGERGDILNP
Mflv_2050|M.gilvum_PYR-GCK MSELRLMAVHAHPDDESSKGAAAMARYVDEGVRVMVVTLTGGERGDILNP
Mvan_4667|M.vanbaalenii_PYR-1 MSELRLMAVHAHPDDESSKGAATMARYVDEGVRVMVVTLTGGERGDILNP
MSMEG_5261|M.smegmatis_MC2_155 MSELRLMAVHAHPDDESSKGAATTARYAAEGARVMVVTLTGGERGDILNP
TH_2167|M.thermoresistible__bu MTELRLMAVHAHPDDESSKGAATTAKYADEGARVMVVTLTGGERGDILNP
MAB_4015c|M.abscessus_ATCC_199 ------MAVHAHPDDESSRGAATLAKYAAEGHQVLVVTATGGERGDILNP
************:***: *:*. ** :*:*** ******:****
MMAR_4385|M.marinum_M AMDLPDVHGHISEIRRDEMAKAAEILGVEHTWLGFVDSGLPKGDPPPPLP
MUL_0198|M.ulcerans_Agy99 AMDLPDVHGHISEIRRDEMAKAAEILGVEHTWLGFVDSGLPKGDPPPPLP
Mb1111|M.bovis_AF2122/97 AMDLPDVHGRIAEIRRDEMTKAAEILGVEHTWLGFVDSGLPKGDLPPPLP
Rv1082|M.tuberculosis_H37Rv AMDLPDVHGRIAEIRRDEMTKAAEILGVEHTWLGFVDSGLPKGDLPPPLP
MLBr_02391|M.leprae_Br4923 AMDLPDVHGHIAEIRRDEMAKAAEILGVEHTWLGFIDSGLPKGDPPPPLP
MAV_1206|M.avium_104 AMDLPEVHGHIAEIRRDEMAKAAEILGVEHTWLGFVDSGLPKGDPPPPLP
Mflv_2050|M.gilvum_PYR-GCK AMDLPEVHGRIHEIRIDEMARAAEILGVEHHWLGFVDSGLPEGDPLPPLP
Mvan_4667|M.vanbaalenii_PYR-1 AMDLPEVHGRMAEIRRDEMARAAEILGVEHHWLGFVDSGLPEGDPPPPLP
MSMEG_5261|M.smegmatis_MC2_155 AMDLPEVHGRIAEVRRDEMAKAAEILGVEHHWLGFVDSGLPEGDPLPPLP
TH_2167|M.thermoresistible__bu AMDLPEVRGRIAEVRRDEMAKAAEILGVEHRWLGFVDSGLPEGDPPPPLP
MAB_4015c|M.abscessus_ATCC_199 AMNRAGVQENLRQVRRQEMALAAKTLGVEHHWLGFTDSGLQLD--PGLLP
**: . *: .: ::* :**: **: ***** **** **** . **
MMAR_4385|M.marinum_M EGCFALVPLEDSIEALVRVVREFRPHVMTTYDENGGYPHPDHIRCHQVSI
MUL_0198|M.ulcerans_Agy99 EGCFALVPLEDSIEALVRVVREFRPHVMTTYDENGGYPHPDHIRCHQVSI
Mb1111|M.bovis_AF2122/97 DDCFARVPLEVSTEALVRVVREFRPHVMTTYDENGGYPHPDHIRCHQVSV
Rv1082|M.tuberculosis_H37Rv DDCFARVPLEVSTEALVRVVREFRPHVMTTYDENGGYPHPDHIRCHQVSV
MLBr_02391|M.leprae_Br4923 DDCFALVPLEVCTEALVRVVRKFRPHVLTTYDENGGYPHPDHIRCHQVSV
MAV_1206|M.avium_104 EGCFALVPLEEAIEALVRVVREFRPHVMTTYDETGGYPHPDHIRCHQVSV
Mflv_2050|M.gilvum_PYR-GCK EGCFALEPLEVPTEALVKVIRDFRPHVMTTYDENGGYPHPDHIKCHQVSV
Mvan_4667|M.vanbaalenii_PYR-1 EGCFALEPLEVPTHALVRVIRDFKPHVITTYDENGGYPHPDHIKCHQVSV
MSMEG_5261|M.smegmatis_MC2_155 DGCFALVPLEEPVKRLVRVIREFRPHVMTTYDENGGYPHPDHIRCHQVSV
TH_2167|M.thermoresistible__bu EGCFATVPLEQATERLVRLIREFRPHVMTTYDENGGYPHPDHIRCHQVSV
MAB_4015c|M.abscessus_ATCC_199 ADGFALVPLAESVACLTAVIEQFRPHVMVTYNECGGYPHPDHIRCHQMAV
. ** ** *. ::..*:***:.**:* *********:***:::
MMAR_4385|M.marinum_M GAYEAAADYLRFPDAGEPWTVS-KLYYIHG---FLRERMRILQDEFIKRG
MUL_0198|M.ulcerans_Agy99 GAYEAAADYLRFPDAGEPWTVS-KLYYIHG---FLRERMRILQDEFIKRG
Mb1111|M.bovis_AF2122/97 AAYEAAGDFCRFPDAGEPWTVS-KLYYVHG---FLRERMQMLQDEFARHG
Rv1082|M.tuberculosis_H37Rv AAYEAAGDFCRFPDAGEPWTVS-KLYYVHG---FLRERMQMLQDEFARHG
MLBr_02391|M.leprae_Br4923 DAYEAACDYRRFPDAGKPWTVS-KLYYNHG---FLRARMQLLHDEFAKHG
MAV_1206|M.avium_104 GAYEAAGDYRRFPDAGEPWTVS-KLYYNHG---FLRARMQLLHDEAVKHG
Mflv_2050|M.gilvum_PYR-GCK AAYEAAADHLLYPDAGEPWSVS-KLYYNHG---FLRQRMQVLQDEFAKHG
Mvan_4667|M.vanbaalenii_PYR-1 AAYEAAADHRLFPEAGDPWTPL-KLYYNHG---FLRQRMQVLQDEFAKHG
MSMEG_5261|M.smegmatis_MC2_155 AAYEAAADHLLYPDAGEPWAVQ-KLYYNHG---FLRQRMQLLQEEFAKNG
TH_2167|M.thermoresistible__bu AAYEAAADYRLFPDAGPPWAVL-KLYYNHG---FIRQRMKLLQDEFEKNG
MAB_4015c|M.abscessus_ATCC_199 AAYGACPDVAKLYYFHEIVRVTPRMVRFAGRAERIVSRMPRRQSAAAAST
** *. * :: * : ** :.
MMAR_4385|M.marinum_M QEGPFGKWLEHWHPDHDPFANRVTTR-----VECSGYFAQRDDALRAHAT
MUL_0198|M.ulcerans_Agy99 QEDPFGKWLEHWHPDHDPFANRVTTR-----VECSGYFGQRDDALRAHAT
Mb1111|M.bovis_AF2122/97 QRGPFEQWLAYWDPDHDFLTSRVTTR-----VECSKYFSQRDDALRAHAT
Rv1082|M.tuberculosis_H37Rv QRGPFEQWLAYWDPDHDFLTSRVTTR-----VECSKYFSQRDDALRAHAT
MLBr_02391|M.leprae_Br4923 QAGPFDKWLAQSNPAHDPFESRVTTR-----VECSAYFSQRDDALRAHAT
MAV_1206|M.avium_104 HEPPFKKWLEHWDPAHDPFESRVTTR-----VECSAYFSQRDDALRAHTT
Mflv_2050|M.gilvum_PYR-GCK EEGPFAKWLEKWDPDDDVLDKRVTTR-----IECAKYFGKRDDALLAHAT
Mvan_4667|M.vanbaalenii_PYR-1 KEGPFATWLEKWDPDEDLLAKRVTTR-----IECAKYFAQRDEALLAHAT
MSMEG_5261|M.smegmatis_MC2_155 QEGPFAKWLEHWDPDNDVFANRVTTR-----VHCAEYFHQRDDALRAHAT
TH_2167|M.thermoresistible__bu MEGPFAKWLERWDPENDVFEKRVTTR-----VECAKYFGRRDDALRAHAT
MAB_4015c|M.abscessus_ATCC_199 DQRLGDVTVPGWVRVSSMLTRRVGSRRATTLVACGDYFCVRDRALRAHAS
: . : ** :* : *. ** ** ** **::
MMAR_4385|M.marinum_M QIDPNAEFFAAPLSWQRELWPTEEFELARSRIPIGLPETELFAGIESSQ-
MUL_0198|M.ulcerans_Agy99 QIDPNAEFFAAPLSWQRELWPTEEFELARSRIPIGLPETELFAGIESSQ-
Mb1111|M.bovis_AF2122/97 QIDPNAEFFAAPLAWQERLWPTEEFELARSRIPARPPETELFAGIEP---
Rv1082|M.tuberculosis_H37Rv QIDPNAEFFAAPLAWQERLWPTEEFELARSRIPARPPETELFAGIEP---
MLBr_02391|M.leprae_Br4923 QIDPKAEFFAAPISWQQRLWPTEEFELARSRVPTRLPEHDLFAGIEAAG-
MAV_1206|M.avium_104 QIDPDHDFFAAPIAWQQRLWPTEEFELARSRVPVRLPEDDLFAGIEPDA-
Mflv_2050|M.gilvum_PYR-GCK QIDPNSFFFTTPMEWQQRLWPTEEFELARSRVPVVLPETDLFAGIEDLGD
Mvan_4667|M.vanbaalenii_PYR-1 QIDPNSFFFSTPMEWQQRLWPTEEFELARSRVPVTLPETHLFAGIEGYE-
MSMEG_5261|M.smegmatis_MC2_155 QIDPKGDFFHAPIEWQQRLWPTEEFELARARVPVTLPEDDLFKGVEP---
TH_2167|M.thermoresistible__bu QIDPNSFFFAAPIEWQERLWPTEEFELARSRVPVRLPETDLFAGIEDHVD
MAB_4015c|M.abscessus_ATCC_199 QVDPNGPFFLVPWTWRQHLWPTEKFELAHSRVATKAPETDLFAGL-----
*:**. ** .* *:..*****:****::*:. ** .** *:
MMAR_4385|M.marinum_M ---
MUL_0198|M.ulcerans_Agy99 ---
Mb1111|M.bovis_AF2122/97 ---
Rv1082|M.tuberculosis_H37Rv ---
MLBr_02391|M.leprae_Br4923 ---
MAV_1206|M.avium_104 ---
Mflv_2050|M.gilvum_PYR-GCK ---
Mvan_4667|M.vanbaalenii_PYR-1 ---
MSMEG_5261|M.smegmatis_MC2_155 ---
TH_2167|M.thermoresistible__bu KLD
MAB_4015c|M.abscessus_ATCC_199 ---