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M. bovis AF2122 / 97 Mb1111 (mca)

annotation: Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase)
coordinates: 1207880 - 1208746
length: 288

VSELRLMAVHAHPDDESSKGAATLARYADEGHRVLVVTLTGGERGEILNPAMDLPDVHGRIAEIRRDEMT
KAAEILGVEHTWLGFVDSGLPKGDLPPPLPDDCFARVPLEVSTEALVRVVREFRPHVMTTYDENGGYPHP
DHIRCHQVSVAAYEAAGDFCRFPDAGEPWTVSKLYYVHGFLRERMQMLQDEFARHGQRGPFEQWLAYWDP
DHDFLTSRVTTRVECSKYFSQRDDALRAHATQIDPNAEFFAAPLAWQERLWPTEEFELARSRIPARPPET
ELFAGIEP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1111mca-100% (288)Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase)
M. bovis AF2122 / 97Mb1203mshB4e-2842.22% (180) N-Acetyl-1-D-myo-Inosityl-2-amino-2-deoxy-alpha-
M. bovis AF2122 / 97Mb0331c-2e-1330.92% (152) hypothetical protein Mb0331c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2050-1e-13778.40% (287) LmbE family protein
M. tuberculosis H37RvRv1082mca1e-174100.00% (288) Mycothiol conjugate amidase Mca (Mycothiol S-conjugate
M. leprae Br4923MLBr_02391-1e-15086.76% (287) hypothetical protein MLBr_02391
M. abscessus ATCC 19977MAB_1203-1e-11667.25% (287) LmbE-like protein
M. marinum MMMAR_4385mca1e-14986.41% (287) mycothiol conjugate amidase Mca
M. avium 104MAV_1206-1e-14784.38% (288) mycothiol conjugate amidase Mca
M. smegmatis MC2 155MSMEG_5261-1e-13877.78% (288) mycothiol conjugate amidase Mca
M. thermoresistible (build 8)TH_2167-1e-14079.09% (287) mycothiol conjugate amidase Mca
M. ulcerans Agy99MUL_0198mca1e-14986.06% (287) mycothiol conjugate amidase Mca
M. vanbaalenii PYR-1Mvan_4667-1e-13878.05% (287) LmbE family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2050|M.gilvum_PYR-GCK          MSELRLMAVHAHPDDESSKGAAAMARYVDEGVRVMVVTLTGGERGDILNP
Mvan_4667|M.vanbaalenii_PYR-1       MSELRLMAVHAHPDDESSKGAATMARYVDEGVRVMVVTLTGGERGDILNP
MSMEG_5261|M.smegmatis_MC2_155      MSELRLMAVHAHPDDESSKGAATTARYAAEGARVMVVTLTGGERGDILNP
TH_2167|M.thermoresistible__bu      MTELRLMAVHAHPDDESSKGAATTAKYADEGARVMVVTLTGGERGDILNP
Mb1111|M.bovis_AF2122/97            MSELRLMAVHAHPDDESSKGAATLARYADEGHRVLVVTLTGGERGEILNP
Rv1082|M.tuberculosis_H37Rv         MSELRLMAVHAHPDDESSKGAATLARYADEGHRVLVVTLTGGERGEILNP
MMAR_4385|M.marinum_M               MSKLRLMAVHAHPDDESSKGAATLARYADEGHRVLVVTLTGGERGEILNP
MUL_0198|M.ulcerans_Agy99           MSKLRLMAVHAHPDDESSKGAATLARYADEGHRVLVVTLTGGERGEILNP
MLBr_02391|M.leprae_Br4923          MSELRLMAVHAHPDDESSKGAATLARYADEGHRVLVVTLTGGERGEILNP
MAV_1206|M.avium_104                MSELRLMAVHAHPDDESSKGAATLARYADEGHRVLVVTLTGGERGDILNP
MAB_1203|M.abscessus_ATCC_1997      MTGLRLMAVHAHPDDEASKGAATTARYAAEGNEVMVVTLTGGERGDILNP
                                    *: *************:*****: *:*. ** .*:**********:****

Mflv_2050|M.gilvum_PYR-GCK          AMDLPEVHGRIHEIRIDEMARAAEILGVEHHWLGFVDSGLPEGDPLPPLP
Mvan_4667|M.vanbaalenii_PYR-1       AMDLPEVHGRMAEIRRDEMARAAEILGVEHHWLGFVDSGLPEGDPPPPLP
MSMEG_5261|M.smegmatis_MC2_155      AMDLPEVHGRIAEVRRDEMAKAAEILGVEHHWLGFVDSGLPEGDPLPPLP
TH_2167|M.thermoresistible__bu      AMDLPEVRGRIAEVRRDEMAKAAEILGVEHRWLGFVDSGLPEGDPPPPLP
Mb1111|M.bovis_AF2122/97            AMDLPDVHGRIAEIRRDEMTKAAEILGVEHTWLGFVDSGLPKGDLPPPLP
Rv1082|M.tuberculosis_H37Rv         AMDLPDVHGRIAEIRRDEMTKAAEILGVEHTWLGFVDSGLPKGDLPPPLP
MMAR_4385|M.marinum_M               AMDLPDVHGHISEIRRDEMAKAAEILGVEHTWLGFVDSGLPKGDPPPPLP
MUL_0198|M.ulcerans_Agy99           AMDLPDVHGHISEIRRDEMAKAAEILGVEHTWLGFVDSGLPKGDPPPPLP
MLBr_02391|M.leprae_Br4923          AMDLPDVHGHIAEIRRDEMAKAAEILGVEHTWLGFIDSGLPKGDPPPPLP
MAV_1206|M.avium_104                AMDLPEVHGHIAEIRRDEMAKAAEILGVEHTWLGFVDSGLPKGDPPPPLP
MAB_1203|M.abscessus_ATCC_1997      AMDRPEVAANIGAIRREEMAKAAAELGVRHRWLGYVDSGLPQGDPLPPLP
                                    *** *:* ..:  :* :**::**  ***.* ***::*****:**  ****

Mflv_2050|M.gilvum_PYR-GCK          EGCFALEPLEVPTEALVKVIRDFRPHVMTTYDENGGYPHPDHIKCHQVSV
Mvan_4667|M.vanbaalenii_PYR-1       EGCFALEPLEVPTHALVRVIRDFKPHVITTYDENGGYPHPDHIKCHQVSV
MSMEG_5261|M.smegmatis_MC2_155      DGCFALVPLEEPVKRLVRVIREFRPHVMTTYDENGGYPHPDHIRCHQVSV
TH_2167|M.thermoresistible__bu      EGCFATVPLEQATERLVRLIREFRPHVMTTYDENGGYPHPDHIRCHQVSV
Mb1111|M.bovis_AF2122/97            DDCFARVPLEVSTEALVRVVREFRPHVMTTYDENGGYPHPDHIRCHQVSV
Rv1082|M.tuberculosis_H37Rv         DDCFARVPLEVSTEALVRVVREFRPHVMTTYDENGGYPHPDHIRCHQVSV
MMAR_4385|M.marinum_M               EGCFALVPLEDSIEALVRVVREFRPHVMTTYDENGGYPHPDHIRCHQVSI
MUL_0198|M.ulcerans_Agy99           EGCFALVPLEDSIEALVRVVREFRPHVMTTYDENGGYPHPDHIRCHQVSI
MLBr_02391|M.leprae_Br4923          DDCFALVPLEVCTEALVRVVRKFRPHVLTTYDENGGYPHPDHIRCHQVSV
MAV_1206|M.avium_104                EGCFALVPLEEAIEALVRVVREFRPHVMTTYDETGGYPHPDHIRCHQVSV
MAB_1203|M.abscessus_ATCC_1997      SDSFALVPIEEPIAKLVAVVREFRPHVMTTYDENGGYPHPDHIRCHEVSM
                                    ...**  *:*     ** ::*.*:***:*****.*********:**:**:

Mflv_2050|M.gilvum_PYR-GCK          AAYEAAADHLLYPDAGEPWSVSKLYYNHGFLRQRMQVLQDEFAKHGEEGP
Mvan_4667|M.vanbaalenii_PYR-1       AAYEAAADHRLFPEAGDPWTPLKLYYNHGFLRQRMQVLQDEFAKHGKEGP
MSMEG_5261|M.smegmatis_MC2_155      AAYEAAADHLLYPDAGEPWAVQKLYYNHGFLRQRMQLLQEEFAKNGQEGP
TH_2167|M.thermoresistible__bu      AAYEAAADYRLFPDAGPPWAVLKLYYNHGFIRQRMKLLQDEFEKNGMEGP
Mb1111|M.bovis_AF2122/97            AAYEAAGDFCRFPDAGEPWTVSKLYYVHGFLRERMQMLQDEFARHGQRGP
Rv1082|M.tuberculosis_H37Rv         AAYEAAGDFCRFPDAGEPWTVSKLYYVHGFLRERMQMLQDEFARHGQRGP
MMAR_4385|M.marinum_M               GAYEAAADYLRFPDAGEPWTVSKLYYIHGFLRERMRILQDEFIKRGQEGP
MUL_0198|M.ulcerans_Agy99           GAYEAAADYLRFPDAGEPWTVSKLYYIHGFLRERMRILQDEFIKRGQEDP
MLBr_02391|M.leprae_Br4923          DAYEAACDYRRFPDAGKPWTVSKLYYNHGFLRARMQLLHDEFAKHGQAGP
MAV_1206|M.avium_104                GAYEAAGDYRRFPDAGEPWTVSKLYYNHGFLRARMQLLHDEAVKHGHEPP
MAB_1203|M.abscessus_ATCC_1997      AAFEAAADPEQFPEAGEPWTVSKIYYNHGFMRARMQLLNDECKKHGYKGP
                                     *:*** *   :*:** **:  *:** ***:* **::*::*  :.*   *

Mflv_2050|M.gilvum_PYR-GCK          FAKWLEKWDPDDDVLDKRVTTRIECAKYFGKRDDALLAHATQIDPNSFFF
Mvan_4667|M.vanbaalenii_PYR-1       FATWLEKWDPDEDLLAKRVTTRIECAKYFAQRDEALLAHATQIDPNSFFF
MSMEG_5261|M.smegmatis_MC2_155      FAKWLEHWDPDNDVFANRVTTRVHCAEYFHQRDDALRAHATQIDPKGDFF
TH_2167|M.thermoresistible__bu      FAKWLERWDPENDVFEKRVTTRVECAKYFGRRDDALRAHATQIDPNSFFF
Mb1111|M.bovis_AF2122/97            FEQWLAYWDPDHDFLTSRVTTRVECSKYFSQRDDALRAHATQIDPNAEFF
Rv1082|M.tuberculosis_H37Rv         FEQWLAYWDPDHDFLTSRVTTRVECSKYFSQRDDALRAHATQIDPNAEFF
MMAR_4385|M.marinum_M               FGKWLEHWHPDHDPFANRVTTRVECSGYFAQRDDALRAHATQIDPNAEFF
MUL_0198|M.ulcerans_Agy99           FGKWLEHWHPDHDPFANRVTTRVECSGYFGQRDDALRAHATQIDPNAEFF
MLBr_02391|M.leprae_Br4923          FDKWLAQSNPAHDPFESRVTTRVECSAYFSQRDDALRAHATQIDPKAEFF
MAV_1206|M.avium_104                FKKWLEHWDPAHDPFESRVTTRVECSAYFSQRDDALRAHTTQIDPDHDFF
MAB_1203|M.abscessus_ATCC_1997      FDEWLERWPADDDTFDRRVTTRVPCADFFDARDAALRAHASQIPPDSSFF
                                    *  **    . .* :  *****: *: :*  ** ** **::** *.  **

Mflv_2050|M.gilvum_PYR-GCK          TTPMEWQQRLWPTEEFELARSRVPVVLPETDLFAGIEDLGD---
Mvan_4667|M.vanbaalenii_PYR-1       STPMEWQQRLWPTEEFELARSRVPVTLPETHLFAGIEGYE----
MSMEG_5261|M.smegmatis_MC2_155      HAPIEWQQRLWPTEEFELARARVPVTLPEDDLFKGVEP------
TH_2167|M.thermoresistible__bu      AAPIEWQERLWPTEEFELARSRVPVRLPETDLFAGIEDHVDKLD
Mb1111|M.bovis_AF2122/97            AAPLAWQERLWPTEEFELARSRIPARPPETELFAGIEP------
Rv1082|M.tuberculosis_H37Rv         AAPLAWQERLWPTEEFELARSRIPARPPETELFAGIEP------
MMAR_4385|M.marinum_M               AAPLSWQRELWPTEEFELARSRIPIGLPETELFAGIESSQ----
MUL_0198|M.ulcerans_Agy99           AAPLSWQRELWPTEEFELARSRIPIGLPETELFAGIESSQ----
MLBr_02391|M.leprae_Br4923          AAPISWQQRLWPTEEFELARSRVPTRLPEHDLFAGIEAAG----
MAV_1206|M.avium_104                AAPIAWQQRLWPTEEFELARSRVPVRLPEDDLFAGIEPDA----
MAB_1203|M.abscessus_ATCC_1997      AVPREFERKLWPTEDFELAKSRVPTSTPEDDLFAGVETK-----
                                     .*  ::..*****:****::*:*   ** .** *:*