For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MASIAQWIEGSRPRTWPNAVAPVIAGTGAAAAAGSAVWWKALLALAVSVCMIIGVNFANDYSDGIRGTDD DRVGPLRLVGSRLASPASVKAVAFAFLALGAAAGLALAITTAWWLVAVGAVCVAGAWFYTGGSKPYGYSG FGEIAVFVFFGLVAVLGTEYAQTSTVSPVGVVLAVAIGSFSSAVLVANNLRDIPTDRESGKITLAVRLGD ARTRVLFPALLAVPVLASIGLGVAHPWRLLGLVMLPLIAKAARPVVTRASGPALIPTLRDTGLAMLGWAI LTAAALAWLS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3958 | - | - | 100% (290) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0548c | menA | 1e-107 | 67.01% (288) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase |
| M. gilvum PYR-GCK | Mflv_0038 | - | 1e-106 | 68.88% (286) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase |
| M. tuberculosis H37Rv | Rv0534c | menA | 1e-107 | 67.01% (288) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase |
| M. leprae Br4923 | MLBr_02406 | - | 1e-102 | 65.73% (286) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase |
| M. marinum M | MMAR_0880 | menA | 1e-108 | 68.29% (287) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase, MenA |
| M. avium 104 | MAV_4611 | menA | 1e-111 | 68.75% (288) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase |
| M. smegmatis MC2 155 | MSMEG_0988 | menA | 1e-110 | 69.10% (288) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase |
| M. thermoresistible (build 8) | TH_3412 | - | 3e-06 | 27.40% (281) | PUTATIVE putative major facilitator superfamily MFS_1 |
| M. ulcerans Agy99 | MUL_0633 | menA | 1e-107 | 67.25% (287) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase |
| M. vanbaalenii PYR-1 | Mvan_0880 | - | 1e-108 | 69.10% (288) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0880|M.marinum_M --------------------------------------------------
MUL_0633|M.ulcerans_Agy99 --------------------------------------------------
MAV_4611|M.avium_104 --------------------------------------------------
MLBr_02406|M.leprae_Br4923 --------------------------------------------------
Mb0548c|M.bovis_AF2122/97 --------------------------------------------------
Rv0534c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0038|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0880|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0988|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3958|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3412|M.thermoresistible__bu MTQCAVRAGAREWAGLGVLAVPTVLLGLDVTVLYLVLPAVAADLAPSPVQ
MMAR_0880|M.marinum_M --------------------------------------------------
MUL_0633|M.ulcerans_Agy99 --------------------------------------------------
MAV_4611|M.avium_104 --------------------------------------------------
MLBr_02406|M.leprae_Br4923 --------------------------------------------------
Mb0548c|M.bovis_AF2122/97 --------------------------------------------------
Rv0534c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_0038|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0880|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0988|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3958|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3412|M.thermoresistible__bu TLWIMDAYGFFIAGFLITMGTLGDRIGRRRLLTIGVTAFAGASVLAALAP
MMAR_0880|M.marinum_M ----------------------MVANIAQWISGARPRTLPNAVAPVVAGT
MUL_0633|M.ulcerans_Agy99 -----MLCMPPCDRQRGPRQDAMVANIAQWISGARPRTLPNAVAPVVAGT
MAV_4611|M.avium_104 -----------------------MANLGQWISGARPRTLPNALAPVVAGT
MLBr_02406|M.leprae_Br4923 -----------------------MASFAQWISGARPRTLPNAVAPVVAGT
Mb0548c|M.bovis_AF2122/97 -----------------------MASFAQWVSGARPRTLPNAIAPVVAGT
Rv0534c|M.tuberculosis_H37Rv -----------------------MASFAQWVSGARPRTLPNAIAPVVAGT
Mflv_0038|M.gilvum_PYR-GCK -----------------------MASLAQWIEGARPRTLPNAVAPVIAGT
Mvan_0880|M.vanbaalenii_PYR-1 -----------------------MASLAQWVEGARPRTLPNAVAPVIAGT
MSMEG_0988|M.smegmatis_MC2_155 -----------------------MASFAQWIEGARPRTLPNAVSPVIAGT
MAB_3958|M.abscessus_ATCC_1997 -----------------------MASIAQWIEGSRPRTWPNAVAPVIAGT
TH_3412|M.thermoresistible__bu SAELLIVARALLGVAGATLMPSTLSLISNMFVDAAQRALAIGVWATMFAV
:: :.: . .: *: . .: ..: ..
MMAR_0880|M.marinum_M GAAA------WLHAAVWWKA--LLALVVAVALTVGVNYANDYSDGIRGTD
MUL_0633|M.ulcerans_Agy99 GAAA------WLHAAVWWKA--LLALVVAVALTVGVNYANDYSDGIRGTD
MAV_4611|M.avium_104 GAAA------WLHAAVWWKA--LLALVVAVAMTVGVNYANDYSDGIRGTD
MLBr_02406|M.leprae_Br4923 GTAA------WLHSAVWWKA--LLALVVAVALVIGVNYANDYSDGIRGTD
Mb0548c|M.bovis_AF2122/97 GAAA------WLHAAVWWKA--LLALAVAVALVIGVNYANDYSDGIRGTD
Rv0534c|M.tuberculosis_H37Rv GAAA------WLHAAVWWKA--LLALAVAVALVIGVNYANDYSDGIRGTD
Mflv_0038|M.gilvum_PYR-GCK GAAA------WLDGASWWKA--LLALVVAVALIIGVNYANDYSDGIRGTD
Mvan_0880|M.vanbaalenii_PYR-1 GAAA------WLEAASWWKA--LLALVVAVALIIGVNYANDYSDGIRGTD
MSMEG_0988|M.smegmatis_MC2_155 GAAA------WLDAAVWWKA--LLALAVSLALIVGVNFANDYSDGIRGTD
MAB_3958|M.abscessus_ATCC_1997 GAAA------AAGSAVWWKA--LLALAVSVCMIIGVNFANDYSDGIRGTD
TH_3412|M.thermoresistible__bu GMAAGPVVGGALVDRFWWGAAFLLAVPVAAAVLLGARLLPEYADPQAGRL
* ** ** * ***: *: .: :*.. :*:* *
MMAR_0880|M.marinum_M DDRTGPMRLVGSRLATPRSVLIAAIVSLMIGAAAGLALALASAPWLIAVG
MUL_0633|M.ulcerans_Agy99 DDRTGPMRLVGSRLATPRSVLIAAIVSLMIGAAAGLALALASAPWLIAVG
MAV_4611|M.avium_104 DDRAGPVRLVGSRLAAPRAVLGAAIASLAVGALAGLALALSSAPWLIAVG
MLBr_02406|M.leprae_Br4923 DHRAGPMRLVGSRLAFPRSVLTAAVVGLTVSTVAGLALALLSAPWLIMVG
Mb0548c|M.bovis_AF2122/97 DDRVGPVRLVGSRLATPRSVLTAAMTSLALGALAGLVLALLSAPWLIAVG
Rv0534c|M.tuberculosis_H37Rv DDRVGPVRLVGSRLATPRSVLTAAMTSLALGALAGLVLALLSAPWLIAVG
Mflv_0038|M.gilvum_PYR-GCK DVRSGPLRLVGSKLAAPKSVLTAAVVSLAVGALAGLVLAWFSAPWLIAVG
Mvan_0880|M.vanbaalenii_PYR-1 DVRSGPLRLVGSRLASPKSVLTAAVASLAVGAAAGLVLAWFSAPWLIAVG
MSMEG_0988|M.smegmatis_MC2_155 DVRSGPLRLVGSKLASPRAVLTAAIVSLAVGAVAGLALAVTSAPWLIAVG
MAB_3958|M.abscessus_ATCC_1997 DDRVGPLRLVGSRLASPASVKAVAFAFLALGAAAGLALAITTAWWLVAVG
TH_3412|M.thermoresistible__bu DLRSVALSLL-AILAAIYAVKHVAVHGVDGVAVAACALAAAAATVFVHRQ
* * .: *: : ** :* .*. : : *. .** :* ::
MMAR_0880|M.marinum_M AGCIAGAWLYTGGSRPYGYSGLGEVAVFVFFGLVAVLGTQYTQALRVDWV
MUL_0633|M.ulcerans_Agy99 AGCIAGAWLYTGGSRPYGYSGLGEVAVFVFFGLVTVLGTQYTQALRVDWV
MAV_4611|M.avium_104 AACIAGAWLYTGGSKPYGYTGFGEVAVFVFFGLVAVLGTEYTQALRVDWV
MLBr_02406|M.leprae_Br4923 ATCIAGAWLYTGSSKPYGYKGFGEVAVFVFFGLVAVLGTEYTQALRVDWV
Mb0548c|M.bovis_AF2122/97 AICIAGAWLYTGGSKPYGYAGFGELAVFVFFGPVAVLGTQYTQALRVDWV
Rv0534c|M.tuberculosis_H37Rv AICIAGAWLYTGGSKPYGYAGFGELAVFVFFGPVAVLGTQYTQALRVDWV
Mflv_0038|M.gilvum_PYR-GCK AVCIAGAWLYTGGSKPYGYLGLGEVAVFVFFGLVAVLGTQYTQALRVDWV
Mvan_0880|M.vanbaalenii_PYR-1 AVCIAGAWLYTGGSKPYGYSGLGEVAVFVFFGLVAVLGTQYTQALRVDWV
MSMEG_0988|M.smegmatis_MC2_155 AVCIAGAWLYTGGKKPYGYQGLGEVAVFIFFGLVAVLGTQYVQALRVDWV
MAB_3958|M.abscessus_ATCC_1997 AVCVAGAWFYTGGSKPYGYSGFGEIAVFVFFGLVAVLGTEYAQTSTVSPV
TH_3412|M.thermoresistible__bu RRLDAPLLDVT----LFADRAFTAALTVLLIGLIGVGGTMYLVTQFLQLV
* * :. .: ..:::* : * ** * : :. *
MMAR_0880|M.marinum_M G-------------LALAVATGALSSAVLVANNLRDIPTDAQSHKITLAV
MUL_0633|M.ulcerans_Agy99 G-------------LALAVATGALSSAVLVANNLRDIPTDAQAHKITLAV
MAV_4611|M.avium_104 G-------------LVLAVAVGALSSSVLVANNLRDIPTDARSGKITLAV
MLBr_02406|M.leprae_Br4923 G-------------LVLAVSTGALSSSVLVANNLRDIHTDTQSHKFTLAV
Mb0548c|M.bovis_AF2122/97 G-------------LAQAVATGALSCSVLVANNLRDIPTDARADKITLAV
Rv0534c|M.tuberculosis_H37Rv G-------------LAQAVATGALSCSVLVANNLRDIPTDARADKITLAV
Mflv_0038|M.gilvum_PYR-GCK G-------------LTLAVAIGCLSSAVLVANNLRDIPTDAESGKITLAV
Mvan_0880|M.vanbaalenii_PYR-1 G-------------VTLAVATGCLSSAVLVANNLRDIPTDAQSGKITLAV
MSMEG_0988|M.smegmatis_MC2_155 G-------------LVLAVAMGSLSSAVLVANNLRDIPTDAQTGKITLAV
MAB_3958|M.abscessus_ATCC_1997 G-------------VVLAVAIGSFSSAVLVANNLRDIPTDRESGKITLAV
TH_3412|M.thermoresistible__bu EGLTPVRAGWWMGPPALAMFVAAIGAPLIARRVRPGVVMAATLGVSVLGY
. *: ..:...::. . .: .*.
MMAR_0880|M.marinum_M RLGDARTR-----------VLYQALLVTAAVLTLALTLATPWCAVG----
MUL_0633|M.ulcerans_Agy99 RLGDARTR-----------VLYQALLVTAAVLTLALTLATPWCAVG----
MAV_4611|M.avium_104 RLGDARTR-----------VLYQALLSAAVALTLVLVAATPWCAAG----
MLBr_02406|M.leprae_Br4923 RLGDAHTR-----------QLYQALLVATGVLTVVLMVATSWCAVG----
Mb0548c|M.bovis_AF2122/97 RLGDARTR-----------MLYQGLLAVAGVLTFVLMLATPWCVVG----
Rv0534c|M.tuberculosis_H37Rv RLGDARTR-----------MLYQGLLAVAGVLTFVLMLATPWCVVG----
Mflv_0038|M.gilvum_PYR-GCK RLGGAKTR-----------VLFTVLTAIPFVLTLVLIAATPWCAAG----
Mvan_0880|M.vanbaalenii_PYR-1 RLGDTKTR-----------ALFQTLMVVAFTLTLLLMLATPWCAVG----
MSMEG_0988|M.smegmatis_MC2_155 RLGDVRTR-----------VLFQVLVGVAMVLTLVLMLATPWAAAG----
MAB_3958|M.abscessus_ATCC_1997 RLGDARTR-----------VLFPALLAVPVLASIGLGVAHPWRLLG----
TH_3412|M.thermoresistible__bu AVLASAGRGDGPAVVVAFAFVYLGLGAIAALGTDIVVGAAPAAKSGSAAA
: * :: * . : : * . *
MMAR_0880|M.marinum_M -------------------LLATPLALRAAAP--VRAGRGGAALIPVLRD
MUL_0633|M.ulcerans_Agy99 -------------------LLATPVALRAAAP--VRAGRGGAALIPVLRD
MAV_4611|M.avium_104 -------------------LVATPLALRAATP--VRSGRGGAELIPVLRD
MLBr_02406|M.leprae_Br4923 -------------------LVATPLALRAMRP--VRSGRMGPDLTPVLRD
Mb0548c|M.bovis_AF2122/97 -------------------LVAAPLALRAAGP--VRSGRGGRELIPVLRD
Rv0534c|M.tuberculosis_H37Rv -------------------LVAAPLALRAAGP--VRSGRGGRELIPVLRD
Mflv_0038|M.gilvum_PYR-GCK -------------------LLALPLALRAAGP--VRGGQGGKDLIPVLKN
Mvan_0880|M.vanbaalenii_PYR-1 -------------------LVALPLAVRAAKP--VRNGSAGKDLIPVLKH
MSMEG_0988|M.smegmatis_MC2_155 -------------------LVALPLAARAAAP--VRRGLGGKDLIPVLRD
MAB_3958|M.abscessus_ATCC_1997 -------------------LVMLPLIAKAARP--VVTRASGPALIPTLRD
TH_3412|M.thermoresistible__bu MSETVQELGIAVGVALLGSVTAAVYRSRMTGPEGVAEGVGGPDAERLAES
: : * * * .
MMAR_0880|M.marinum_M T---------------------------------GLAMMVWAIAMSAALA
MUL_0633|M.ulcerans_Agy99 T---------------------------------GLAMMVWAIAMSAALA
MAV_4611|M.avium_104 T---------------------------------GLAMVVWAVAVAAALT
MLBr_02406|M.leprae_Br4923 T---------------------------------GLAMVVWAIAVAGALT
Mb0548c|M.bovis_AF2122/97 T---------------------------------GLAMLVWALAVAGALA
Rv0534c|M.tuberculosis_H37Rv T---------------------------------GLAMLVWALAVAGALA
Mflv_0038|M.gilvum_PYR-GCK T---------------------------------GLTMLVWAVVVAAALI
Mvan_0880|M.vanbaalenii_PYR-1 T---------------------------------GLTMLVWAVAVAVALA
MSMEG_0988|M.smegmatis_MC2_155 T---------------------------------GLTMLVWALAVSIPLA
MAB_3958|M.abscessus_ATCC_1997 T---------------------------------GLAMLGWAILTAAALA
TH_3412|M.thermoresistible__bu LPAAVSVADRVPGEAVRLAQDAFAAGVNIAALIGGAAVVVVAVVCATALR
* ::: *: : .*
MMAR_0880|M.marinum_M LAA----
MUL_0633|M.ulcerans_Agy99 LAA----
MAV_4611|M.avium_104 WGT----
MLBr_02406|M.leprae_Br4923 LAGSVTY
Mb0548c|M.bovis_AF2122/97 FGQLS--
Rv0534c|M.tuberculosis_H37Rv FGQLS--
Mflv_0038|M.gilvum_PYR-GCK LG-----
Mvan_0880|M.vanbaalenii_PYR-1 FG-----
MSMEG_0988|M.smegmatis_MC2_155 FH-----
MAB_3958|M.abscessus_ATCC_1997 WLS----
TH_3412|M.thermoresistible__bu HLRPLD-