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VANIAQWISGARPRTLPNAVAPVVAGTGAAAWLHAAVWWKALLALVVAVALTVGVNYANDYSDGIRGTDD DRTGPMRLVGSRLATPRSVLIAAIVSLMIGAAAGLALALASAPWLIAVGAGCIAGAWLYTGGSRPYGYSG LGEVAVFVFFGLVAVLGTQYTQALRVDWVGLALAVATGALSSAVLVANNLRDIPTDAQSHKITLAVRLGD ARTRVLYQALLVTAAVLTLALTLATPWCAVGLLATPLALRAAAPVRAGRGGAALIPVLRDTGLAMMVWAI AMSAALALAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0880 | menA | - | 100% (291) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase, MenA |
| M. marinum M | MMAR_0475 | - | 9e-05 | 25.56% (270) | transmembrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0548c | menA | 1e-136 | 82.93% (287) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase |
| M. gilvum PYR-GCK | Mflv_0038 | - | 1e-128 | 79.17% (288) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase |
| M. tuberculosis H37Rv | Rv0534c | menA | 1e-136 | 82.93% (287) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase |
| M. leprae Br4923 | MLBr_02406 | - | 1e-132 | 80.97% (289) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase |
| M. abscessus ATCC 19977 | MAB_3958 | - | 1e-108 | 68.29% (287) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase |
| M. avium 104 | MAV_4611 | menA | 1e-140 | 86.01% (286) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase |
| M. smegmatis MC2 155 | MSMEG_0988 | menA | 1e-129 | 79.79% (287) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase |
| M. thermoresistible (build 8) | TH_3288 | - | 2e-09 | 79.41% (34) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0633 | menA | 1e-160 | 98.97% (291) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase |
| M. vanbaalenii PYR-1 | Mvan_0880 | - | 1e-131 | 80.49% (287) | 1,4-dihydroxy-2-naphthoate octaprenyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0880|M.marinum_M -----------------MVANIAQWISGARPRTLPNAVAPVVAGTGAAAW
MUL_0633|M.ulcerans_Agy99 MLCMPPCDRQRGPRQDAMVANIAQWISGARPRTLPNAVAPVVAGTGAAAW
TH_3288|M.thermoresistible__bu --------------------------------------------------
MLBr_02406|M.leprae_Br4923 ------------------MASFAQWISGARPRTLPNAVAPVVAGTGTAAW
MAV_4611|M.avium_104 ------------------MANLGQWISGARPRTLPNALAPVVAGTGAAAW
Mb0548c|M.bovis_AF2122/97 ------------------MASFAQWVSGARPRTLPNAIAPVVAGTGAAAW
Rv0534c|M.tuberculosis_H37Rv ------------------MASFAQWVSGARPRTLPNAIAPVVAGTGAAAW
Mflv_0038|M.gilvum_PYR-GCK ------------------MASLAQWIEGARPRTLPNAVAPVIAGTGAAAW
Mvan_0880|M.vanbaalenii_PYR-1 ------------------MASLAQWVEGARPRTLPNAVAPVIAGTGAAAW
MSMEG_0988|M.smegmatis_MC2_155 ------------------MASFAQWIEGARPRTLPNAVSPVIAGTGAAAW
MAB_3958|M.abscessus_ATCC_1997 ------------------MASIAQWIEGSRPRTWPNAVAPVIAGTGAAAA
MMAR_0880|M.marinum_M LHAAVWWKALLALVVAVALTVGVNYANDYSDGIRGTDDDRTGPMRLVGSR
MUL_0633|M.ulcerans_Agy99 LHAAVWWKALLALVVAVALTVGVNYANDYSDGIRGTDDDRTGPMRLVGSR
TH_3288|M.thermoresistible__bu --------------------------------------------------
MLBr_02406|M.leprae_Br4923 LHSAVWWKALLALVVAVALVIGVNYANDYSDGIRGTDDHRAGPMRLVGSR
MAV_4611|M.avium_104 LHAAVWWKALLALVVAVAMTVGVNYANDYSDGIRGTDDDRAGPVRLVGSR
Mb0548c|M.bovis_AF2122/97 LHAAVWWKALLALAVAVALVIGVNYANDYSDGIRGTDDDRVGPVRLVGSR
Rv0534c|M.tuberculosis_H37Rv LHAAVWWKALLALAVAVALVIGVNYANDYSDGIRGTDDDRVGPVRLVGSR
Mflv_0038|M.gilvum_PYR-GCK LDGASWWKALLALVVAVALIIGVNYANDYSDGIRGTDDVRSGPLRLVGSK
Mvan_0880|M.vanbaalenii_PYR-1 LEAASWWKALLALVVAVALIIGVNYANDYSDGIRGTDDVRSGPLRLVGSR
MSMEG_0988|M.smegmatis_MC2_155 LDAAVWWKALLALAVSLALIVGVNFANDYSDGIRGTDDVRSGPLRLVGSK
MAB_3958|M.abscessus_ATCC_1997 AGSAVWWKALLALAVSVCMIIGVNFANDYSDGIRGTDDDRVGPLRLVGSR
MMAR_0880|M.marinum_M LATPRSVLIAAIVSLMIGAAAGLALALASAPWLIAVGAGCIAGAWLYTGG
MUL_0633|M.ulcerans_Agy99 LATPRSVLIAAIVSLMIGAAAGLALALASAPWLIAVGAGCIAGAWLYTGG
TH_3288|M.thermoresistible__bu --------------------------------------------------
MLBr_02406|M.leprae_Br4923 LAFPRSVLTAAVVGLTVSTVAGLALALLSAPWLIMVGATCIAGAWLYTGS
MAV_4611|M.avium_104 LAAPRAVLGAAIASLAVGALAGLALALSSAPWLIAVGAACIAGAWLYTGG
Mb0548c|M.bovis_AF2122/97 LATPRSVLTAAMTSLALGALAGLVLALLSAPWLIAVGAICIAGAWLYTGG
Rv0534c|M.tuberculosis_H37Rv LATPRSVLTAAMTSLALGALAGLVLALLSAPWLIAVGAICIAGAWLYTGG
Mflv_0038|M.gilvum_PYR-GCK LAAPKSVLTAAVVSLAVGALAGLVLAWFSAPWLIAVGAVCIAGAWLYTGG
Mvan_0880|M.vanbaalenii_PYR-1 LASPKSVLTAAVASLAVGAAAGLVLAWFSAPWLIAVGAVCIAGAWLYTGG
MSMEG_0988|M.smegmatis_MC2_155 LASPRAVLTAAIVSLAVGAVAGLALAVTSAPWLIAVGAVCIAGAWLYTGG
MAB_3958|M.abscessus_ATCC_1997 LASPASVKAVAFAFLALGAAAGLALAITTAWWLVAVGAVCVAGAWFYTGG
MMAR_0880|M.marinum_M SRPYGYSGLGEVAVFVFFGLVAVLGTQYTQALRVDWVGLALAVATGALSS
MUL_0633|M.ulcerans_Agy99 SRPYGYSGLGEVAVFVFFGLVTVLGTQYTQALRVDWVGLALAVATGALSS
TH_3288|M.thermoresistible__bu --------------------------------------------------
MLBr_02406|M.leprae_Br4923 SKPYGYKGFGEVAVFVFFGLVAVLGTEYTQALRVDWVGLVLAVSTGALSS
MAV_4611|M.avium_104 SKPYGYTGFGEVAVFVFFGLVAVLGTEYTQALRVDWVGLVLAVAVGALSS
Mb0548c|M.bovis_AF2122/97 SKPYGYAGFGELAVFVFFGPVAVLGTQYTQALRVDWVGLAQAVATGALSC
Rv0534c|M.tuberculosis_H37Rv SKPYGYAGFGELAVFVFFGPVAVLGTQYTQALRVDWVGLAQAVATGALSC
Mflv_0038|M.gilvum_PYR-GCK SKPYGYLGLGEVAVFVFFGLVAVLGTQYTQALRVDWVGLTLAVAIGCLSS
Mvan_0880|M.vanbaalenii_PYR-1 SKPYGYSGLGEVAVFVFFGLVAVLGTQYTQALRVDWVGVTLAVATGCLSS
MSMEG_0988|M.smegmatis_MC2_155 KKPYGYQGLGEVAVFIFFGLVAVLGTQYVQALRVDWVGLVLAVAMGSLSS
MAB_3958|M.abscessus_ATCC_1997 SKPYGYSGFGEIAVFVFFGLVAVLGTEYAQTSTVSPVGVVLAVAIGSFSS
MMAR_0880|M.marinum_M AVLVANNLRDIPTDAQSHKITLAVRLGDARTRVLYQALLVTAAVLTLALT
MUL_0633|M.ulcerans_Agy99 AVLVANNLRDIPTDAQAHKITLAVRLGDARTRVLYQALLVTAAVLTLALT
TH_3288|M.thermoresistible__bu --------------------------------------------------
MLBr_02406|M.leprae_Br4923 SVLVANNLRDIHTDTQSHKFTLAVRLGDAHTRQLYQALLVATGVLTVVLM
MAV_4611|M.avium_104 SVLVANNLRDIPTDARSGKITLAVRLGDARTRVLYQALLSAAVALTLVLV
Mb0548c|M.bovis_AF2122/97 SVLVANNLRDIPTDARADKITLAVRLGDARTRMLYQGLLAVAGVLTFVLM
Rv0534c|M.tuberculosis_H37Rv SVLVANNLRDIPTDARADKITLAVRLGDARTRMLYQGLLAVAGVLTFVLM
Mflv_0038|M.gilvum_PYR-GCK AVLVANNLRDIPTDAESGKITLAVRLGGAKTRVLFTVLTAIPFVLTLVLI
Mvan_0880|M.vanbaalenii_PYR-1 AVLVANNLRDIPTDAQSGKITLAVRLGDTKTRALFQTLMVVAFTLTLLLM
MSMEG_0988|M.smegmatis_MC2_155 AVLVANNLRDIPTDAQTGKITLAVRLGDVRTRVLFQVLVGVAMVLTLVLM
MAB_3958|M.abscessus_ATCC_1997 AVLVANNLRDIPTDRESGKITLAVRLGDARTRVLFPALLAVPVLASIGLG
MMAR_0880|M.marinum_M LATPWCAVGLLATPLALRAAAPVRAGRGGAALIPVLRDTGLAMMVWAIAM
MUL_0633|M.ulcerans_Agy99 LATPWCAVGLLATPVALRAAAPVRAGRGGAALIPVLRDTGLAMMVWAIAM
TH_3288|M.thermoresistible__bu ----------------------VRAGSGGAALIPVLRDTGLTMLVWSIAV
MLBr_02406|M.leprae_Br4923 VATSWCAVGLVATPLALRAMRPVRSGRMGPDLTPVLRDTGLAMVVWAIAV
MAV_4611|M.avium_104 AATPWCAAGLVATPLALRAATPVRSGRGGAELIPVLRDTGLAMVVWAVAV
Mb0548c|M.bovis_AF2122/97 LATPWCVVGLVAAPLALRAAGPVRSGRGGRELIPVLRDTGLAMLVWALAV
Rv0534c|M.tuberculosis_H37Rv LATPWCVVGLVAAPLALRAAGPVRSGRGGRELIPVLRDTGLAMLVWALAV
Mflv_0038|M.gilvum_PYR-GCK AATPWCAAGLLALPLALRAAGPVRGGQGGKDLIPVLKNTGLTMLVWAVVV
Mvan_0880|M.vanbaalenii_PYR-1 LATPWCAVGLVALPLAVRAAKPVRNGSAGKDLIPVLKHTGLTMLVWAVAV
MSMEG_0988|M.smegmatis_MC2_155 LATPWAAAGLVALPLAARAAAPVRRGLGGKDLIPVLRDTGLTMLVWALAV
MAB_3958|M.abscessus_ATCC_1997 VAHPWRLLGLVMLPLIAKAARPVVTRASGPALIPTLRDTGLAMLGWAILT
* * * *.*:.***:*: *::
MMAR_0880|M.marinum_M SAALALAA----
MUL_0633|M.ulcerans_Agy99 SAALALAA----
TH_3288|M.thermoresistible__bu GTALALG-----
MLBr_02406|M.leprae_Br4923 AGALTLAGSVTY
MAV_4611|M.avium_104 AAALTWGT----
Mb0548c|M.bovis_AF2122/97 AGALAFGQLS--
Rv0534c|M.tuberculosis_H37Rv AGALAFGQLS--
Mflv_0038|M.gilvum_PYR-GCK AAALILG-----
Mvan_0880|M.vanbaalenii_PYR-1 AVALAFG-----
MSMEG_0988|M.smegmatis_MC2_155 SIPLAFH-----
MAB_3958|M.abscessus_ATCC_1997 AAALAWLS----
. .*