For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TTLLSDSDYARAEQMLFPHRARRVPGTVLTPQWFADGARFWYRIGTRYVAVDPGVKTRRAAFDHDALAAA LSVAAGQAVTGADLPIQAVQIRADDTVLFSAFGRNWRWADRVCTESDAAAPIPGGIPSPDERWDAFGREG NIWVRSRADGTEHALTDDAEPYFDYGGLPDTTGGRALMRALGIPAPIILHWSPDSTRILVARIDQREVPE LVLVESSPADGGRPVEHRTRYSMPGENTVATMTWNVLDVEQRTIVRQQTEPTPIMHNVALIYAWWSSADA VHYLHQSRDARTLQLRRLAPATGAVTTLITDTGQTRVDPTVVLGDPHMVRVLDNGEILWWSQRDGWGHLY LYSADGVQVTQITAGSWLVSSVLWVDEKARQVYFTANGLVEADPYLRQLCRIGLDGNGFIRLTDDELDHD AVSPPQGGYLVDRASSPSLPPRSVVLDGDGQVVVELETPDTDDLKILGWQPPERFRTTASDGRTPIYGLL WRPHDLDPDRTYPIIEHIYPGPQLYRAGPMFNPPHYGEPEAFAALGFAVVAIDGRGSAGRSKAFHDHSYG DLGNAGALDDHIVAIRELGQRYPWLDTARVGITGQSAGGFAAARAVLRYPDFYSVAVAVSGNHDNALNLA MWAEHYHGDLSAEGKAAISNTTLAANLKGKLLLIHGELDDNAHPYMTMRLADALIKADKDFDLIMIPGAE HSLYGWLHYSLRRTWDYFVRHLHGTEPPGYRLQPLLLPSLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2919c | - | - | 100% (742) | dipeptidyl peptidase IV |
| M. abscessus ATCC 19977 | MAB_4725 | - | 2e-07 | 29.86% (144) | peptidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4393 | - | 3e-07 | 30.56% (144) | peptidase S9 prolyl oligopeptidase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_4633 | - | 7e-11 | 25.70% (323) | peptidase S9, prolyl oligopeptidase |
| M. thermoresistible (build 8) | TH_4519 | - | 9e-10 | 24.58% (297) | PUTATIVE peptidase S9, prolyl oligopeptidase active site domain |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3954 | - | 9e-08 | 24.29% (317) | peptidase S9 prolyl oligopeptidase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4633|M.smegmatis_MC2_155 -----------------MNSTP------------FHDLDAYLDLPRVSGL
Mvan_3954|M.vanbaalenii_PYR-1 -----MKSCPAMCYEFRMSSAPEQPTPATPGTTAFHDLDEFLALPRVAGL
Mflv_4393|M.gilvum_PYR-GCK ---------------MALP--------------DLIPVEDLFNPPTRAAA
TH_4519|M.thermoresistible__bu ---------------------------------------VAEQVRATYGA
MAB_2919c|M.abscessus_ATCC_199 MTTLLSDSDYARAEQMLFPHRARRVPGTVLTPQWFADGARFWYRIGTRYV
MSMEG_4633|M.smegmatis_MC2_155 AVSP-----------DGTRVVTTVSTLNAKR------------TEFVTAL
Mvan_3954|M.vanbaalenii_PYR-1 AVSP-----------DGTRVVTTVSRLDDKR------------TEFVSAL
Mflv_4393|M.gilvum_PYR-GCK KISP-----------DGTRMAFLAPSNNR------------------LNV
TH_4519|M.thermoresistible__bu SLSP-----------DATAFAHLVDDGGFP-----------------RAV
MAB_2919c|M.abscessus_ATCC_199 AVDPGVKTRRAAFDHDALAAALSVAAGQAVTGADLPIQAVQIRADDTVLF
:.* *. . . .
MSMEG_4633|M.smegmatis_MC2_155 WELDPAGQQPARRLTRGLKGESAPVFTADGDVLFLAVRPTE--DDEKPP-
Mvan_3954|M.vanbaalenii_PYR-1 WELDPSGQQPARRLTFGAKGESAPEFTADGDLLFLAARPTG--DDDEPTR
Mflv_4393|M.gilvum_PYR-GCK WVENLDPESGGLRRVTDDDNRSVLHFEWTDDPRWLIYLQDT--NGDENWH
TH_4519|M.thermoresistible__bu QRFLRGWRASSSRDVELPVVGPVRRVLHSPDGGWLACEVAP--DGSDRSQ
MAB_2919c|M.abscessus_ATCC_199 SAFGRNWRWADRVCTESDAAAPIPGGIPSPDERWDAFGREGNIWVRSRAD
. . . * : .
MSMEG_4633|M.smegmatis_MC2_155 AALWRLPAHGGEAHEMLSLPGGVSAAASARTADVTVVAAPLLPSAADVEA
Mvan_3954|M.vanbaalenii_PYR-1 KALWRLPAAGGEAHEVATLPGGVDRVTSAREAATTLITSAMLASATDVDD
Mflv_4393|M.gilvum_PYR-GCK VHRVDLDDPEAPAVDLTPFPG--AMALPVREVKNGRTTVMVNNRDATLLD
TH_4519|M.thermoresistible__bu IWVVTTDPDDRGAHRIDSWPPDAPEGAAELIAWDGNRIAAILTGQDGVGS
MAB_2919c|M.abscessus_ATCC_199 GTEHALTDDAEPYFDYGGLPDTTGGRALMRALGIPAPIILHWSPDSTRIL
*
MSMEG_4633|M.smegmatis_MC2_155 DRSLRKARKDNKVSAILHTGYPVRQWDHDLGPDLPHLFDADG--ARNLTE
Mvan_3954|M.vanbaalenii_PYR-1 DKRLRAARKDNKVSAVLHAGYPVRYWDHDLGPEQPHLFDITEERPRDLTP
Mflv_4393|M.gilvum_PYR-GCK IHELDIATGDLTLIAK-NPGHVNGWLSSDDGDLFATALTADGDLELSRWD
TH_4519|M.thermoresistible__bu SCLIDPADGSTVVLDRRSGGRLVDAWA---GAALIRVGPRGYRELIMLHG
MAB_2919c|M.abscessus_ATCC_199 VARIDQREVPELVLVESSPADGGRPVEHRTRYSMPGENTVATMTWNVLDV
: : .
MSMEG_4633|M.smegmatis_MC2_155 RPGVALRESTFDVSPDGAFVVATWHVPAPGAATRSTLVR-IDRETGARTT
Mvan_3954|M.vanbaalenii_PYR-1 TPGQALREAHFDLSRDGAFLVTTWQGPAPGAALRTTLVH-VDVATGRRTT
Mflv_4393|M.gilvum_PYR-GCK RDDEALRPIIRFDGTDYPIGIHPLVLTPDGTGVWLGFNRGTDRTRLVHVD
TH_4519|M.thermoresistible__bu NTEMALLPSDPGSTTDFGVILDDHSARRLRRGPDGELTKLYQPAKRYPRE
MAB_2919c|M.abscessus_ATCC_199 EQRTIVRQQTEPTPIMHNVALIYAWWSSADAVHYLHQSRDARTLQLRRLA
: . : :
MSMEG_4633|M.smegmatis_MC2_155 IAEDPQADLE-HPVIAPDGGALAFTRETHSTPTEPPRITLCCMRFGNDDE
Mvan_3954|M.vanbaalenii_PYR-1 IVDDRDADLG-NPAVSPDGQSVAYTRETISTPRKAPRITLCLLRFGEEP-
Mflv_4393|M.gilvum_PYR-GCK LATGEETDVDSHPTFDVDPRAAVSPLLPAPLIQDRRTGELLGVRYYGER-
TH_4519|M.thermoresistible__bu STEG-----YVRALIRSDNGAGYARLLEVTTTADGVAYQVVAERPGHDL-
MAB_2919c|M.abscessus_ATCC_199 PATGAVTTLITDTGQTRVDPTVVLGDPHMVRVLDNGEILWWSQRDGWGHL
. . . : . *
MSMEG_4633|M.smegmatis_MC2_155 QLG-----EWAEVATEWDRWPSSLAWSADASALIVTADDNGRGP-----V
Mvan_3954|M.vanbaalenii_PYR-1 ----------VELTTGWDRWPTSVTWSADGSSVIITADDHGRGP-----I
Mflv_4393|M.gilvum_PYR-GCK --------------------QTIRALDSRFGDILANLEKLSDGD-----L
TH_4519|M.thermoresistible__bu ---------------------DEFVVSDDLSTVALLWNIDGASE-----L
MAB_2919c|M.abscessus_ATCC_199 YLYSADGVQVTQITAGSWLVSSVLWVDEKARQVYFTANGLVEADPYLRQL
. : : . :
MSMEG_4633|M.smegmatis_MC2_155 FSVHPDTGTVTRLTDDDHTYTDVCPAPGGIIYALRSSYAVPPHPVRIDPD
Mvan_3954|M.vanbaalenii_PYR-1 FAVDPDTGAVRTLVADDFTYSDVRPAPGGVLFALRSSYAAPQHPVRIDAD
Mflv_4393|M.gilvum_PYR-GCK GNLSSDENGVRWIVG----FNHDRDPGATYLYDHSTGESRLLFRPLPQLD
TH_4519|M.thermoresistible__bu QILQYADNTLSEPIPLPGMVAGELSISAGGSMVAMTVESPWLPPTVELVD
MAB_2919c|M.abscessus_ATCC_199 CRIGLDGNGFIRLTDDELDHDAVSPPQGGYLVDRASSPSLPPRSVVLDGD
: . . . : : *
MSMEG_4633|M.smegmatis_MC2_155 GTVTELPCFDAPALPGSLT-----EITATAEDG-TPVRSWLTLPESTDP-
Mvan_3954|M.vanbaalenii_PYR-1 GTVTVLDCVALPDLPGTLT-----EVTATTADG-RTVRSWMVLPHGEAAG
Mflv_4393|M.gilvum_PYR-GCK -----------PSQLAPMR-----PVTITARDG-LPLQSYLTLPVGVEAK
TH_4519|M.thermoresistible__bu PRTRQWELIDREPSTGPVTGTPT-LERLTARDG-LELTGWLYRPPTGVQP
MAB_2919c|M.abscessus_ATCC_199 GQVVVELETPDTDDLKILGWQPPERFRTTASDGRTPIYGLLWRPHDLDPD
: *: ** : . : *
MSMEG_4633|M.smegmatis_MC2_155 ---------APLVLWVHGGPLGSWNTWHWR----WNPWLLTAHGYAVLMP
Mvan_3954|M.vanbaalenii_PYR-1 SYSSRERSSAPLLLWIHGGPLASWNAWHWR----WNPWVMAARGYAVLLP
Mflv_4393|M.gilvum_PYR-GCK S--------LPLVLVVHGGPWFR-DSWGFD----GHVQLLANRGYAVLQV
TH_4519|M.thermoresistible__bu ---------VGAMIFLHGGPEGQ-SRPGYN----EYFPPLLDRGITVFTP
MAB_2919c|M.abscessus_ATCC_199 R-------TYPIIEHIYPGPQLYRAGPMFNPPHYGEPEAFAALGFAVVAI
: :: ** : : * :*.
MSMEG_4633|M.smegmatis_MC2_155 DPALSTGYGQDFIARGWGAWG--EAPYTDLMAATDAACEHPRVDASRTAA
Mvan_3954|M.vanbaalenii_PYR-1 DPALSTGYGQEFIQRGWGSWG--FAPYTDLMAATDAACAHPRVDETRTAA
Mflv_4393|M.gilvum_PYR-GCK NFRGSTGFGKAFLKAAIGEFA--GKMHDDLIDGVNWAVEQGYADPDRVAI
TH_4519|M.thermoresistible__bu NVRGSGGFGRSFVHADDKENR--FRAIDDVADCVHYLVRNGLAPADRIAC
MAB_2919c|M.abscessus_ATCC_199 DGRGSAGRSKAFHDHSYGDLGNAGALDDHIVAIRELGQRYPWLDTARVGI
: * * .: * .: . * .
MSMEG_4633|M.smegmatis_MC2_155 MGGSFGGYMANWVAGHT-DRFDAIVTHASLWALDQFAPTTD-------GA
Mvan_3954|M.vanbaalenii_PYR-1 MGGSFGGYMANWIAGHT-DRFAAIVTHASLWALDQFGATTD-------GG
Mflv_4393|M.gilvum_PYR-GCK LGGSYGGYAALVGVTFTPDVFAAAVDYVGISNLANFMRTLPPIARPQLAN
TH_4519|M.thermoresistible__bu AGWSYGGYLTQAALAFHPDLFAAGISVCGMSDLTTWYQTTEPWIAQSSYT
MAB_2919c|M.abscessus_ATCC_199 TGQSAGGFAAARAVLRYPDFYSVAVAVSGNHDNALNLAMWA--------E
* * **: : * : . : .
MSMEG_4633|M.smegmatis_MC2_155 YWWAREMTPEMMQ------RNSPHRFVDQINTPMLVIHGDKDYRVPIGEA
Mvan_3954|M.vanbaalenii_PYR-1 YWWAREMTPEMAA------ANSPHLFVSQIATPMLVIHGDKDYRVPIGEA
Mflv_4393|M.gilvum_PYR-GCK NWHAYVGDPDDPEQLADMMARSPITKVDQIRTPLFVIQGANDVRVVQAE-
TH_4519|M.thermoresistible__bu EYGHPVADRDLLER------LSPLTHAAAVTAPLLLVHGASDTNVPPSE-
MAB_2919c|M.abscessus_ATCC_199 HYHGDLSAEGKAA-------ISNTTLAANLKGKLLLIHGELDDNAHPYM-
: * . : :::::* * ..
MSMEG_4633|M.smegmatis_MC2_155 LRLWYELLTESALPADDNGDSPHRFLYYPAENHWVLTPQHA--KLWYQVV
Mvan_3954|M.vanbaalenii_PYR-1 LRLWYELLSSSALPAADDGSTEHRFLYFPSENHWVLSPQHA--KIWYQVV
Mflv_4393|M.gilvum_PYR-GCK --------SDNLVNALRDRGVEVDYLIQTDEGHGAVNAENT--IEMWEAV
TH_4519|M.thermoresistible__bu --------SIQMHTALERLGRPVKLLMFDDDGHEIVRRENR--ATLVEAM
MAB_2919c|M.abscessus_ATCC_199 --------TMRLADALIKADKDFDLIMIPGAEHSLYGWLHYSLRRTWDYF
: * . : * : : .
MSMEG_4633|M.smegmatis_MC2_155 TAFLDENLRNEPAQWPELLG---
Mvan_3954|M.vanbaalenii_PYR-1 LAFLAHHVLGQDSELPEMLG---
Mflv_4393|M.gilvum_PYR-GCK VRFFARHIGGRA-----------
TH_4519|M.thermoresistible__bu SHWLMSAFAERRREAS-------
MAB_2919c|M.abscessus_ATCC_199 VRHLHGTEPPGYRLQPLLLPSLG
: