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VNRRALLLSGIALVAVAACERDSTTEPSPGHPDPLEALKAGNARFAGGQMAHPHQSPSRRAELTGDQDPM AIVFSCIDSRVPPEIVFDQGLGDLFVVRTGAQDYDALIEGSIEYGAVMDHTPLMVVLGHQRCGAVTAAVK SLEQHNPAPAHLADVVEALKPAYLRAKQAPQNSLDDLIEGTIRAQIQLTVNALRADPPLASNTKNNELRI VGAYYTLDTGVVSWLDQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2564 | - | - | 100% (227) | carbonic anhydrase |
| M. abscessus ATCC 19977 | MAB_2656 | - | e-100 | 78.17% (229) | carbonic anhydrase (carbonate dehydratase) |
| M. abscessus ATCC 19977 | MAB_0559 | - | 2e-31 | 39.57% (187) | carbonic anhydrase (carbonate dehydratase) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3619c | - | 1e-33 | 39.46% (185) | carbonic anhydrase (carbonate dehydratase) (carbonic |
| M. gilvum PYR-GCK | Mflv_1439 | - | 5e-32 | 40.84% (191) | carbonic anhydrase |
| M. tuberculosis H37Rv | Rv3588c | - | 1e-33 | 39.46% (185) | carbonic anhydrase |
| M. leprae Br4923 | MLBr_01919 | - | 4e-36 | 42.16% (185) | putative carbonic anhydrase |
| M. marinum M | MMAR_5088 | - | 2e-33 | 41.94% (186) | carbonic anhydrase |
| M. avium 104 | MAV_0565 | - | 1e-32 | 38.22% (191) | carbonic anhydrase |
| M. smegmatis MC2 155 | MSMEG_6082 | - | 3e-33 | 43.46% (191) | carbonic anhydrase |
| M. thermoresistible (build 8) | TH_0590 | - | 1e-33 | 38.78% (196) | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC |
| M. ulcerans Agy99 | MUL_4164 | - | 8e-34 | 41.94% (186) | carbonic anhydrase |
| M. vanbaalenii PYR-1 | Mvan_5345 | - | 3e-33 | 41.08% (185) | carbonic anhydrase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3619c|M.bovis_AF2122/97 -------------------------MPNTNPVAAWKALKEGNERFVAGRP
Rv3588c|M.tuberculosis_H37Rv -------------------------MPNTNPVAAWKALKEGNERFVAGRP
MLBr_01919|M.leprae_Br4923 -------------------------MFNTNPIAAWKALKEGNERFVAGQP
MMAR_5088|M.marinum_M ----------------------MAGMPNTNPITAWKALSEGNERFVAGKP
MUL_4164|M.ulcerans_Agy99 -------------------------MPNTNPITAWKALSEGNERFVAGKP
MAV_0565|M.avium_104 -------------------------MPNTSPVTAWKSLKEGNERFVAGKP
TH_0590|M.thermoresistible__bu ----------------------MATMPNTSPVTAWKALKEGNERFVAGKP
Mflv_1439|M.gilvum_PYR-GCK -------------------------MPNTNPLTAWKALREGNERFVAGKP
Mvan_5345|M.vanbaalenii_PYR-1 -------------------------MPNTNPLTAWKALKEGNERFVAGKP
MSMEG_6082|M.smegmatis_MC2_155 -------------------------MPNSNPVAAWKALKDGNARFVAGQP
MAB_2564|M.abscessus_ATCC_1997 MNRRALLLSGIALVAVAACERDSTTEPSPGHPDPLEALKAGNARFAGGQM
... . ::* ** **..*:
Mb3619c|M.bovis_AF2122/97 QHPSQSVDHRAGLAAGQKPTAVIFGCADSRVAAEIIFDQGLGDMFVVRTA
Rv3588c|M.tuberculosis_H37Rv QHPSQSVDHRAGLAAGQKPTAVIFGCADSRVAAEIIFDQGLGDMFVVRTA
MLBr_01919|M.leprae_Br4923 AHPSQSVEHRASLADTQKPLAVIFGCADSRVAAELVFDQGLGDMFVVRTV
MMAR_5088|M.marinum_M LHPSQSVDHRASLASGQKPTAVIFGCADSRVAAEIIFDQGLGDMFVVRTA
MUL_4164|M.ulcerans_Agy99 LHPSQSVDHRASLASGQKPTAVIFGCADSRVAAEIIFDQGLGDMFVVRTA
MAV_0565|M.avium_104 QHPSQSVEHRASLAAGQSPTAVVFGCSDSRVAAELIFDQGLGDMFVVRTA
TH_0590|M.thermoresistible__bu LHPSQSIEHRATLTDEQGPTAVVFGCADSRVAAEIIFDQGLGDMFVVRTA
Mflv_1439|M.gilvum_PYR-GCK QHPSQSTDHRASLAAAQKPTAVVFGCGDSRVAAEILFDQGLGDMFVVRTA
Mvan_5345|M.vanbaalenii_PYR-1 EHPSQSIERRTSLAAAQKPTAVVFGCGDSRVAAEIIFDQGLGDMFVVRTA
MSMEG_6082|M.smegmatis_MC2_155 LHPSQGIERRASLTQAQRPTAVVFGCGDSRVAAEILFDQGLGDMFVVRTA
MAB_2564|M.abscessus_ATCC_1997 AHPHQSPSRRAELTGDQDPMAIVFSCIDSRVPPEIVFDQGLGDLFVVRTG
** *. .:*: *: * * *::*.* ****..*::*******:*****
Mb3619c|M.bovis_AF2122/97 GHVTDSAVLGSIEYAVTVLNVPLIVVLGHDSCGAVNAALAAINDGTLPGG
Rv3588c|M.tuberculosis_H37Rv GHVIDSAVLGSIEYAVTVLNVPLIVVLGHDSCGAVNAALAAINDGTLPGG
MLBr_01919|M.leprae_Br4923 GHVIDSAVLGSIEYAVTVLDVPLVVVLGHDSCGAVTAALAAINEGNLPSG
MMAR_5088|M.marinum_M GHVIDSAVLGSIEYAVTVLNVPLVVVLGHDSCGAVNAALTAINEGSVPGG
MUL_4164|M.ulcerans_Agy99 GHVIDSAVLGSIEYAVTVLNVPLVVVLGHDSCGAVNAALTAINEGSVPGG
MAV_0565|M.avium_104 GQAIDTAVLGSIEFAVSVLNVPLIVVLGHDSCGAVKAALGAIEEGAIPGG
TH_0590|M.thermoresistible__bu GHVIDAAVLGSVEYAVTVLEVPLIVVLGHDSCGAVKATLEALDEGVVPGG
Mflv_1439|M.gilvum_PYR-GCK GHVIDSAVLGSIEYAVSVLEVPLVVVLGHDSCGAVKAALGALDDGEVPGG
Mvan_5345|M.vanbaalenii_PYR-1 GHVIDGAVLGSIEYAVSVLHVPLIVVLGHDSCGAVGATLAALDEGEVPGG
MSMEG_6082|M.smegmatis_MC2_155 GHVIDNAVLGSIEYAVTVLKVPLIVVLGHDSCGAVKATLSALDEGEVPSG
MAB_2564|M.abscessus_ATCC_1997 AQDYDALIEGSIEYGAVMDHTPLMVVLGHQRCGAVTAAVKSLEQHNPAPA
.: * : **:*:.. : ..**:*****: **** *:: :::: . .
Mb3619c|M.bovis_AF2122/97 YVRDVVERVAPSVLLGRRDGLSRVDEFEQRHVHETVAILM---ARSSAIS
Rv3588c|M.tuberculosis_H37Rv YVRDVVERVAPSVLLGRRDGLSRVDEFEQRHVHETVAILM---ARSSAIS
MLBr_01919|M.leprae_Br4923 YVRDVVERVAPSVLLGRRDGLTRVDEFEERHVHETVAQAM---ARSTAIA
MMAR_5088|M.marinum_M YVRDVVERVAPSILMGRRDGLKRVDEFEQRHIQETVAQLM---ARSTAIS
MUL_4164|M.ulcerans_Agy99 YVRDVVERVAPSILMGRREGLKRVDEFEQRHIQETVAQLM---ARSTAIS
MAV_0565|M.avium_104 FVRDVVERVAPSILMGRREGLSRVDEFEERHVRETVAQLV---SRSTTIA
TH_0590|M.thermoresistible__bu YVRDVVERVTPSILLGRRDGLTRVDEFEERHVNETTYQLR---NRSTVIA
Mflv_1439|M.gilvum_PYR-GCK YVRDVVERVMPSILVGRRDGLSRVDEFEARHVTETGKQLL---SRSTAIA
Mvan_5345|M.vanbaalenii_PYR-1 YIRDIVERVMPSILLGRRDGLTRVDEFEARHVTETGKQLL---SRSTAIA
MSMEG_6082|M.smegmatis_MC2_155 FVRDIVERVTPSILLGRKAGLSRVDEFEAQHVNETVAQLQ---MRSTAIA
MAB_2564|M.abscessus_ATCC_1997 HLADVVEALKPAYLRAKQAPQNSLDDLIEGTIRAQIQLTVNALRADPPLA
.: *:** : *: * .:: . :*:: : .. ::
Mb3619c|M.bovis_AF2122/97 ERIAGGSLAIVGVTYQLDDGRAVLRDHIGNIGEEV------
Rv3588c|M.tuberculosis_H37Rv ERIAGGSLAIVGVTYQLDDGRAVLRDHIGNIGEEV------
MLBr_01919|M.leprae_Br4923 QRVAAGTLAIVGVTYHLADGRAVLRTHIGNLGEEVQLSHCS
MMAR_5088|M.marinum_M NRVAAGTLAIVGVTYQLSDGQAVLRDHVGDIGA--------
MUL_4164|M.ulcerans_Agy99 NRVAAGTLAIVGVTYQLSDGQAVLRDHVGDIGA--------
MAV_0565|M.avium_104 ERIGDGTVAVAGVTYHLADGRAALCDHVGDIGE--------
TH_0590|M.thermoresistible__bu ERVAAGDVAIAGVTYHLADGRAQLREYLGDIGEA-------
Mflv_1439|M.gilvum_PYR-GCK EAVNAGKLAIVGLTYHLADGKVDLRDHIGDIGES-------
Mvan_5345|M.vanbaalenii_PYR-1 EAVRDGKLAIVGLTYQLADGKAVLRDHIGDIGEA-------
MSMEG_6082|M.smegmatis_MC2_155 QGLAAGTQAIVGTTYHLADGRVELRSHLGDIGEV-------
MAB_2564|M.abscessus_ATCC_1997 SNTKNNELRIVGAYYTLDTGVVSWLDQ--------------
. . :.* * * * .