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M. ulcerans Agy99 MUL_4164 (-)

annotation: carbonic anhydrase
coordinates: 4636324 - 4636941
length: 205

PNTNPITAWKALSEGNERFVAGKPLHPSQSVDHRASLASGQKPTAVIFGCADSRVAAEIIFDQGLGDMFV
VRTAGHVIDSAVLGSIEYAVTVLNVPLVVVLGHDSCGAVNAALTAINEGSVPGGYVRDVVERVAPSILMG
RREGLKRVDEFEQRHIQETVAQLMARSTAISNRVAAGTLAIVGVTYQLSDGQAVLRDHVGDIGA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_4164--100% (205)carbonic anhydrase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3619c-1e-10085.78% (204) carbonic anhydrase (carbonate dehydratase) (carbonic
M. gilvum PYR-GCKMflv_1439-8e-9380.39% (204) carbonic anhydrase
M. tuberculosis H37RvRv3588c-1e-10186.27% (204) carbonic anhydrase
M. leprae Br4923MLBr_01919-6e-9682.84% (204) putative carbonic anhydrase
M. abscessus ATCC 19977MAB_0559-6e-7667.16% (201) carbonic anhydrase (carbonate dehydratase)
M. marinum MMMAR_5088-1e-11399.51% (205) carbonic anhydrase
M. avium 104MAV_0565-9e-9478.92% (204) carbonic anhydrase
M. smegmatis MC2 155MSMEG_6082-5e-8773.53% (204) carbonic anhydrase
M. thermoresistible (build 8)TH_0590-3e-9177.94% (204) CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC
M. vanbaalenii PYR-1Mvan_5345-3e-9278.43% (204) carbonic anhydrase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1439|M.gilvum_PYR-GCK          ---MPNTNPLTAWKALREGNERFVAGKPQHPSQSTDHRASLAAAQKPTAV
Mvan_5345|M.vanbaalenii_PYR-1       ---MPNTNPLTAWKALKEGNERFVAGKPEHPSQSIERRTSLAAAQKPTAV
MUL_4164|M.ulcerans_Agy99           ---MPNTNPITAWKALSEGNERFVAGKPLHPSQSVDHRASLASGQKPTAV
MMAR_5088|M.marinum_M               MAGMPNTNPITAWKALSEGNERFVAGKPLHPSQSVDHRASLASGQKPTAV
Mb3619c|M.bovis_AF2122/97           ---MPNTNPVAAWKALKEGNERFVAGRPQHPSQSVDHRAGLAAGQKPTAV
Rv3588c|M.tuberculosis_H37Rv        ---MPNTNPVAAWKALKEGNERFVAGRPQHPSQSVDHRAGLAAGQKPTAV
MLBr_01919|M.leprae_Br4923          ---MFNTNPIAAWKALKEGNERFVAGQPAHPSQSVEHRASLADTQKPLAV
MAV_0565|M.avium_104                ---MPNTSPVTAWKSLKEGNERFVAGKPQHPSQSVEHRASLAAGQSPTAV
MSMEG_6082|M.smegmatis_MC2_155      ---MPNSNPVAAWKALKDGNARFVAGQPLHPSQGIERRASLTQAQRPTAV
TH_0590|M.thermoresistible__bu      MATMPNTSPVTAWKALKEGNERFVAGKPLHPSQSIEHRATLTDEQGPTAV
MAB_0559|M.abscessus_ATCC_1997      ---MAS-DPKSAWKALKEGNQRFVGGFPQHPSQSVTRRAELANGQNPQVM
                                       * . .* :***:* :** ***.* * ****.  :*: *:  * * .:

Mflv_1439|M.gilvum_PYR-GCK          VFGCGDSRVAAEILFDQGLGDMFVVRTAGHVIDSAVLGSIEYAVSVLEVP
Mvan_5345|M.vanbaalenii_PYR-1       VFGCGDSRVAAEIIFDQGLGDMFVVRTAGHVIDGAVLGSIEYAVSVLHVP
MUL_4164|M.ulcerans_Agy99           IFGCADSRVAAEIIFDQGLGDMFVVRTAGHVIDSAVLGSIEYAVTVLNVP
MMAR_5088|M.marinum_M               IFGCADSRVAAEIIFDQGLGDMFVVRTAGHVIDSAVLGSIEYAVTVLNVP
Mb3619c|M.bovis_AF2122/97           IFGCADSRVAAEIIFDQGLGDMFVVRTAGHVTDSAVLGSIEYAVTVLNVP
Rv3588c|M.tuberculosis_H37Rv        IFGCADSRVAAEIIFDQGLGDMFVVRTAGHVIDSAVLGSIEYAVTVLNVP
MLBr_01919|M.leprae_Br4923          IFGCADSRVAAELVFDQGLGDMFVVRTVGHVIDSAVLGSIEYAVTVLDVP
MAV_0565|M.avium_104                VFGCSDSRVAAELIFDQGLGDMFVVRTAGQAIDTAVLGSIEFAVSVLNVP
MSMEG_6082|M.smegmatis_MC2_155      VFGCGDSRVAAEILFDQGLGDMFVVRTAGHVIDNAVLGSIEYAVTVLKVP
TH_0590|M.thermoresistible__bu      VFGCADSRVAAEIIFDQGLGDMFVVRTAGHVIDAAVLGSVEYAVTVLEVP
MAB_0559|M.abscessus_ATCC_1997      LFGCSDSRVAAEIIFDQGLGDMFIVRTAGQVIDSAVLGSIEYAVAVLGVP
                                    :***.*******::*********:***.*:. * *****:*:**:** **

Mflv_1439|M.gilvum_PYR-GCK          LVVVLGHDSCGAVKAALGALDDGEVPGGYVRDVVERVMPSILVGRRDGLS
Mvan_5345|M.vanbaalenii_PYR-1       LIVVLGHDSCGAVGATLAALDEGEVPGGYIRDIVERVMPSILLGRRDGLT
MUL_4164|M.ulcerans_Agy99           LVVVLGHDSCGAVNAALTAINEGSVPGGYVRDVVERVAPSILMGRREGLK
MMAR_5088|M.marinum_M               LVVVLGHDSCGAVNAALTAINEGSVPGGYVRDVVERVAPSILMGRRDGLK
Mb3619c|M.bovis_AF2122/97           LIVVLGHDSCGAVNAALAAINDGTLPGGYVRDVVERVAPSVLLGRRDGLS
Rv3588c|M.tuberculosis_H37Rv        LIVVLGHDSCGAVNAALAAINDGTLPGGYVRDVVERVAPSVLLGRRDGLS
MLBr_01919|M.leprae_Br4923          LVVVLGHDSCGAVTAALAAINEGNLPSGYVRDVVERVAPSVLLGRRDGLT
MAV_0565|M.avium_104                LIVVLGHDSCGAVKAALGAIEEGAIPGGFVRDVVERVAPSILMGRREGLS
MSMEG_6082|M.smegmatis_MC2_155      LIVVLGHDSCGAVKATLSALDEGEVPSGFVRDIVERVTPSILLGRKAGLS
TH_0590|M.thermoresistible__bu      LIVVLGHDSCGAVKATLEALDEGVVPGGYVRDVVERVTPSILLGRRDGLT
MAB_0559|M.abscessus_ATCC_1997      LIAILGHDSCGAVGATLDALDTGEVPGGYIRDLVVRVMPSILGGRKDGLS
                                    *:.:********* *:* *:: * :*.*::**:* ** **:* **: **.

Mflv_1439|M.gilvum_PYR-GCK          RVDEFEARHVTETGKQLLSRSTAIAEAVNAGKLAIVGLTYHLADGKVDLR
Mvan_5345|M.vanbaalenii_PYR-1       RVDEFEARHVTETGKQLLSRSTAIAEAVRDGKLAIVGLTYQLADGKAVLR
MUL_4164|M.ulcerans_Agy99           RVDEFEQRHIQETVAQLMARSTAISNRVAAGTLAIVGVTYQLSDGQAVLR
MMAR_5088|M.marinum_M               RVDEFEQRHIQETVAQLMARSTAISNRVAAGTLAIVGVTYQLSDGQAVLR
Mb3619c|M.bovis_AF2122/97           RVDEFEQRHVHETVAILMARSSAISERIAGGSLAIVGVTYQLDDGRAVLR
Rv3588c|M.tuberculosis_H37Rv        RVDEFEQRHVHETVAILMARSSAISERIAGGSLAIVGVTYQLDDGRAVLR
MLBr_01919|M.leprae_Br4923          RVDEFEERHVHETVAQAMARSTAIAQRVAAGTLAIVGVTYHLADGRAVLR
MAV_0565|M.avium_104                RVDEFEERHVRETVAQLVSRSTTIAERIGDGTVAVAGVTYHLADGRAALC
MSMEG_6082|M.smegmatis_MC2_155      RVDEFEAQHVNETVAQLQMRSTAIAQGLAAGTQAIVGTTYHLADGRVELR
TH_0590|M.thermoresistible__bu      RVDEFEERHVNETTYQLRNRSTVIAERVAAGDVAIAGVTYHLADGRAQLR
MAB_0559|M.abscessus_ATCC_1997      RVDEFEARHVEETGTKLLQRSQVVADAVKAKKLAIVYLTYKLADGRVVLH
                                    ****** :*: **      ** .::: :     *:.  **:* **:. * 

Mflv_1439|M.gilvum_PYR-GCK          DHIGDIGES-------
Mvan_5345|M.vanbaalenii_PYR-1       DHIGDIGEA-------
MUL_4164|M.ulcerans_Agy99           DHVGDIGA--------
MMAR_5088|M.marinum_M               DHVGDIGA--------
Mb3619c|M.bovis_AF2122/97           DHIGNIGEEV------
Rv3588c|M.tuberculosis_H37Rv        DHIGNIGEEV------
MLBr_01919|M.leprae_Br4923          THIGNLGEEVQLSHCS
MAV_0565|M.avium_104                DHVGDIGE--------
MSMEG_6082|M.smegmatis_MC2_155      SHLGDIGEV-------
TH_0590|M.thermoresistible__bu      EYLGDIGEA-------
MAB_0559|M.abscessus_ATCC_1997      GHVGDIGE--------
                                     ::*::*