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PNTNPVAAWKALKEGNERFVAGRPQHPSQSVDHRAGLAAGQKPTAVIFGCADSRVAAEIIFDQGLGDMFV VRTAGHVIDSAVLGSIEYAVTVLNVPLIVVLGHDSCGAVNAALAAINDGTLPGGYVRDVVERVAPSVLLG RRDGLSRVDEFEQRHVHETVAILMARSSAISERIAGGSLAIVGVTYQLDDGRAVLRDHIGNIGEEV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3588c | - | - | 100% (207) | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) |
| M. tuberculosis H37Rv | Rv3273 | - | 1e-11 | 38.37% (86) | transmembrane carbonic anhydrase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3619c | - | 1e-114 | 99.52% (207) | carbonic anhydrase (carbonate dehydratase) (carbonic |
| M. gilvum PYR-GCK | Mflv_1439 | - | 2e-92 | 79.02% (205) | carbonic anhydrase |
| M. leprae Br4923 | MLBr_01919 | - | 1e-98 | 84.54% (207) | putative carbonic anhydrase |
| M. abscessus ATCC 19977 | MAB_0559 | - | 3e-76 | 67.82% (202) | carbonic anhydrase (carbonate dehydratase) |
| M. marinum M | MMAR_5088 | - | 1e-101 | 86.76% (204) | carbonic anhydrase |
| M. avium 104 | MAV_0565 | - | 1e-92 | 78.05% (205) | carbonic anhydrase |
| M. smegmatis MC2 155 | MSMEG_6082 | - | 3e-85 | 72.68% (205) | carbonic anhydrase |
| M. thermoresistible (build 8) | TH_0590 | - | 2e-89 | 76.59% (205) | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC |
| M. ulcerans Agy99 | MUL_4164 | - | 1e-101 | 86.27% (204) | carbonic anhydrase |
| M. vanbaalenii PYR-1 | Mvan_5345 | - | 6e-92 | 78.05% (205) | carbonic anhydrase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1439|M.gilvum_PYR-GCK ---MPNTNPLTAWKALREGNERFVAGKPQHPSQSTDHRASLAAAQKPTAV
Mvan_5345|M.vanbaalenii_PYR-1 ---MPNTNPLTAWKALKEGNERFVAGKPEHPSQSIERRTSLAAAQKPTAV
Rv3588c|M.tuberculosis_H37Rv ---MPNTNPVAAWKALKEGNERFVAGRPQHPSQSVDHRAGLAAGQKPTAV
Mb3619c|M.bovis_AF2122/97 ---MPNTNPVAAWKALKEGNERFVAGRPQHPSQSVDHRAGLAAGQKPTAV
MLBr_01919|M.leprae_Br4923 ---MFNTNPIAAWKALKEGNERFVAGQPAHPSQSVEHRASLADTQKPLAV
MMAR_5088|M.marinum_M MAGMPNTNPITAWKALSEGNERFVAGKPLHPSQSVDHRASLASGQKPTAV
MUL_4164|M.ulcerans_Agy99 ---MPNTNPITAWKALSEGNERFVAGKPLHPSQSVDHRASLASGQKPTAV
MAV_0565|M.avium_104 ---MPNTSPVTAWKSLKEGNERFVAGKPQHPSQSVEHRASLAAGQSPTAV
MSMEG_6082|M.smegmatis_MC2_155 ---MPNSNPVAAWKALKDGNARFVAGQPLHPSQGIERRASLTQAQRPTAV
TH_0590|M.thermoresistible__bu MATMPNTSPVTAWKALKEGNERFVAGKPLHPSQSIEHRATLTDEQGPTAV
MAB_0559|M.abscessus_ATCC_1997 ---MAS-DPKSAWKALKEGNQRFVGGFPQHPSQSVTRRAELANGQNPQVM
* . .* :***:* :** ***.* * ****. :*: *: * * .:
Mflv_1439|M.gilvum_PYR-GCK VFGCGDSRVAAEILFDQGLGDMFVVRTAGHVIDSAVLGSIEYAVSVLEVP
Mvan_5345|M.vanbaalenii_PYR-1 VFGCGDSRVAAEIIFDQGLGDMFVVRTAGHVIDGAVLGSIEYAVSVLHVP
Rv3588c|M.tuberculosis_H37Rv IFGCADSRVAAEIIFDQGLGDMFVVRTAGHVIDSAVLGSIEYAVTVLNVP
Mb3619c|M.bovis_AF2122/97 IFGCADSRVAAEIIFDQGLGDMFVVRTAGHVTDSAVLGSIEYAVTVLNVP
MLBr_01919|M.leprae_Br4923 IFGCADSRVAAELVFDQGLGDMFVVRTVGHVIDSAVLGSIEYAVTVLDVP
MMAR_5088|M.marinum_M IFGCADSRVAAEIIFDQGLGDMFVVRTAGHVIDSAVLGSIEYAVTVLNVP
MUL_4164|M.ulcerans_Agy99 IFGCADSRVAAEIIFDQGLGDMFVVRTAGHVIDSAVLGSIEYAVTVLNVP
MAV_0565|M.avium_104 VFGCSDSRVAAELIFDQGLGDMFVVRTAGQAIDTAVLGSIEFAVSVLNVP
MSMEG_6082|M.smegmatis_MC2_155 VFGCGDSRVAAEILFDQGLGDMFVVRTAGHVIDNAVLGSIEYAVTVLKVP
TH_0590|M.thermoresistible__bu VFGCADSRVAAEIIFDQGLGDMFVVRTAGHVIDAAVLGSVEYAVTVLEVP
MAB_0559|M.abscessus_ATCC_1997 LFGCSDSRVAAEIIFDQGLGDMFIVRTAGQVIDSAVLGSIEYAVAVLGVP
:***.*******::*********:***.*:. * *****:*:**:** **
Mflv_1439|M.gilvum_PYR-GCK LVVVLGHDSCGAVKAALGALDDGEVPGGYVRDVVERVMPSILVGRRDGLS
Mvan_5345|M.vanbaalenii_PYR-1 LIVVLGHDSCGAVGATLAALDEGEVPGGYIRDIVERVMPSILLGRRDGLT
Rv3588c|M.tuberculosis_H37Rv LIVVLGHDSCGAVNAALAAINDGTLPGGYVRDVVERVAPSVLLGRRDGLS
Mb3619c|M.bovis_AF2122/97 LIVVLGHDSCGAVNAALAAINDGTLPGGYVRDVVERVAPSVLLGRRDGLS
MLBr_01919|M.leprae_Br4923 LVVVLGHDSCGAVTAALAAINEGNLPSGYVRDVVERVAPSVLLGRRDGLT
MMAR_5088|M.marinum_M LVVVLGHDSCGAVNAALTAINEGSVPGGYVRDVVERVAPSILMGRRDGLK
MUL_4164|M.ulcerans_Agy99 LVVVLGHDSCGAVNAALTAINEGSVPGGYVRDVVERVAPSILMGRREGLK
MAV_0565|M.avium_104 LIVVLGHDSCGAVKAALGAIEEGAIPGGFVRDVVERVAPSILMGRREGLS
MSMEG_6082|M.smegmatis_MC2_155 LIVVLGHDSCGAVKATLSALDEGEVPSGFVRDIVERVTPSILLGRKAGLS
TH_0590|M.thermoresistible__bu LIVVLGHDSCGAVKATLEALDEGVVPGGYVRDVVERVTPSILLGRRDGLT
MAB_0559|M.abscessus_ATCC_1997 LIAILGHDSCGAVGATLDALDTGEVPGGYIRDLVVRVMPSILGGRKDGLS
*:.:********* *:* *:: * :*.*::**:* ** **:* **: **.
Mflv_1439|M.gilvum_PYR-GCK RVDEFEARHVTETGKQLLSRSTAIAEAVNAGKLAIVGLTYHLADGKVDLR
Mvan_5345|M.vanbaalenii_PYR-1 RVDEFEARHVTETGKQLLSRSTAIAEAVRDGKLAIVGLTYQLADGKAVLR
Rv3588c|M.tuberculosis_H37Rv RVDEFEQRHVHETVAILMARSSAISERIAGGSLAIVGVTYQLDDGRAVLR
Mb3619c|M.bovis_AF2122/97 RVDEFEQRHVHETVAILMARSSAISERIAGGSLAIVGVTYQLDDGRAVLR
MLBr_01919|M.leprae_Br4923 RVDEFEERHVHETVAQAMARSTAIAQRVAAGTLAIVGVTYHLADGRAVLR
MMAR_5088|M.marinum_M RVDEFEQRHIQETVAQLMARSTAISNRVAAGTLAIVGVTYQLSDGQAVLR
MUL_4164|M.ulcerans_Agy99 RVDEFEQRHIQETVAQLMARSTAISNRVAAGTLAIVGVTYQLSDGQAVLR
MAV_0565|M.avium_104 RVDEFEERHVRETVAQLVSRSTTIAERIGDGTVAVAGVTYHLADGRAALC
MSMEG_6082|M.smegmatis_MC2_155 RVDEFEAQHVNETVAQLQMRSTAIAQGLAAGTQAIVGTTYHLADGRVELR
TH_0590|M.thermoresistible__bu RVDEFEERHVNETTYQLRNRSTVIAERVAAGDVAIAGVTYHLADGRAQLR
MAB_0559|M.abscessus_ATCC_1997 RVDEFEARHVEETGTKLLQRSQVVADAVKAKKLAIVYLTYKLADGRVVLH
****** :*: ** ** .::: : *:. **:* **:. *
Mflv_1439|M.gilvum_PYR-GCK DHIGDIGES-------
Mvan_5345|M.vanbaalenii_PYR-1 DHIGDIGEA-------
Rv3588c|M.tuberculosis_H37Rv DHIGNIGEEV------
Mb3619c|M.bovis_AF2122/97 DHIGNIGEEV------
MLBr_01919|M.leprae_Br4923 THIGNLGEEVQLSHCS
MMAR_5088|M.marinum_M DHVGDIGA--------
MUL_4164|M.ulcerans_Agy99 DHVGDIGA--------
MAV_0565|M.avium_104 DHVGDIGE--------
MSMEG_6082|M.smegmatis_MC2_155 SHLGDIGEV-------
TH_0590|M.thermoresistible__bu EYLGDIGEA-------
MAB_0559|M.abscessus_ATCC_1997 GHVGDIGE--------
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