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MRTIAIRHRAVIGLSAVALITVGCSNGTSVDVPSPEVGLIATTSSAAPAQPAEVKLIGERDVEVTLTGPI AAKYSSASESQKQALGKPLTGDHNAGTRESGAVFQQFQGGAIIAKNNQAGTPAFIVVGKIRDAWNIQRDA DGTPSITGNNGSAGPLGLPTSDENTEGDQLVSTFEHGKIEYNAKSGEVAVTVNGKVVPSGL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2560 | - | - | 100% (201) | hypothetical protein MAB_2560 |
| M. abscessus ATCC 19977 | MAB_0168c | - | 3e-07 | 31.90% (116) | putative N-acetymuramoyl-L-alanine amidase |
| M. abscessus ATCC 19977 | MAB_2527 | - | 2e-06 | 26.99% (226) | hypothetical protein MAB_2527 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3841 | - | 1e-06 | 30.43% (115) | hypothetical protein Mb3841 |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv3811 | - | 2e-06 | 30.43% (115) | hypothetical protein Rv3811 |
| M. leprae Br4923 | MLBr_01002 | - | 4e-06 | 29.03% (124) | hypothetical protein MLBr_01002 |
| M. marinum M | MMAR_5375 | - | 2e-06 | 28.57% (119) | hypothetical protein MMAR_5375 |
| M. avium 104 | MAV_2699 | - | 7e-78 | 70.30% (202) | hypothetical protein MAV_2699 |
| M. smegmatis MC2 155 | MSMEG_2739 | - | 1e-05 | 26.34% (205) | hypothetical protein MSMEG_2739 |
| M. thermoresistible (build 8) | TH_1521 | - | 2e-07 | 28.93% (121) | POSSIBLE CONSERVED TRANSMEMBRANE ALANINE AND GLYCINE RICH |
| M. ulcerans Agy99 | MUL_4995 | - | 2e-06 | 27.73% (119) | hypothetical protein MUL_4995 |
| M. vanbaalenii PYR-1 | Mvan_5652 | - | 3e-05 | 26.28% (137) | LGFP repeat-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2560|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2699|M.avium_104 --------------------------------------------------
MMAR_5375|M.marinum_M ---MPSRSRAPTMLLTAIAATVVIVSWVLTRPPPSTHEQPSAQDTRLVEQ
MUL_4995|M.ulcerans_Agy99 ------------MLLTAIAATVVIVSWVLTRPPPSTHEQPSAQDTRLVEQ
Mb3841|M.bovis_AF2122/97 -----------------MAATVVIVAWIANRPPASSHEPSPTPNTQLAEQ
Rv3811|M.tuberculosis_H37Rv -----------------MAATVVIVAWIANRPPASSHEPSPTPNTQLAEQ
Mvan_5652|M.vanbaalenii_PYR-1 ---MLYRRPAPSILFTALAATVVMLPWAISGGP-DGDDSPAMPAPQLAQQ
MSMEG_2739|M.smegmatis_MC2_155 MTRPGAKLNTAVRRLTIGLLAVA---LAGLLVPSVASATPESDADAAINS
TH_1521|M.thermoresistible__bu MNGQWARTETALGRFAACLLAVATMTLAGLLSAPEAAATPEEDAGAAIGA
MLBr_01002|M.leprae_Br4923 MS----------KRVRRALANTATTAVVTVLLAPVVTASPTGDADDAITA
MAB_2560|M.abscessus_ATCC_1997 ----------------------------------MRTIAIRHRAVIG---
MAV_2699|M.avium_104 ----------------------------------MKTTAHRRSAVVG---
MMAR_5375|M.marinum_M PLVGLGGGVTVRQLTQDEPFSLVALT-GDLVGTSARMRARQSDGSWGPWY
MUL_4995|M.ulcerans_Agy99 PLVGLGGGVTVRQLTQDEPFSLVALT-GDLVGTSARMRARQSDGSWGPWY
Mb3841|M.bovis_AF2122/97 PLIGLGGGVTVRELTQDTPFSLVALT-GDLAGTSARVRAKRPDGDWGPWY
Rv3811|M.tuberculosis_H37Rv PLIGLGGGVTVRELTQDTPFSLVALT-GDLAGTSARVRAKRPDGDWGPWY
Mvan_5652|M.vanbaalenii_PYR-1 PLADLGGGESIRELHQDTPFSMVALTSEDFAGTSARVRAKKDDGSWGPWY
MSMEG_2739|M.smegmatis_MC2_155 AWEVSGGDGGPLGPRQGDVYAIGAGFGQDFTGGKMFFTPDTGAHYVQGAI
TH_1521|M.thermoresistible__bu AYDASGGPGGPLGPPDGGVYPIGAGFAQNYAHGKMFFTPQTGAHFMQGEI
MLBr_01002|M.leprae_Br4923 AWHKAGGDNSVLGAKKGEVYPLGDGFAQNFASGKLFFTTATGAKLLYGPV
.
MAB_2560|M.abscessus_ATCC_1997 --------------------------LSAVALITVGCSNGTSVDVPSP-E
MAV_2699|M.avium_104 --------------------------LAAVALITVGCSNGKSVDASAPPH
MMAR_5375|M.marinum_M QAEYETAAPDEQG-AGAPATAGTSERPRSTEPVFVGTTNTVEIAVTRPID
MUL_4995|M.ulcerans_Agy99 QAEYETAAPDEQG-AGAPATAGTSERPRSTEPVFVGTTNTVEIAVTRSID
Mb3841|M.bovis_AF2122/97 QTEYETEPRDPAGTDGSVELGGLNPGPRSTDPVFVGTTTTVQVAVTRPID
Rv3811|M.tuberculosis_H37Rv QTEYETEPRDPAGTDGSVELGGLNPGPRSTDPVFVGTTTTVQVAVTRPID
Mvan_5652|M.vanbaalenii_PYR-1 EAEPLEG------------VGADLPGPRGTEPVFVGRTTTVQVAVTRPSD
MSMEG_2739|M.smegmatis_MC2_155 LEKYEALGGPADSDLGFPTIDEGAGRA-PDSRNSTFSAPDNPVIFWTPDT
TH_1521|M.thermoresistible__bu LAKYESLGGPADSDLGFPTLSESPGRVGPDSRNVIFSAPDRPVIFWTPDT
MLBr_01002|M.leprae_Br4923 LGKYESLGGPVNSDLGFPIIDEVPGLAGPDSRVSIFAASDNPVIFWTPDH
: : .
MAB_2560|M.abscessus_ATCC_1997 VGLIATTSSAAP---------AQPAEVKLIGERDVEVTLTGP--------
MAV_2699|M.avium_104 AAASATSTSANP---------AQPTEVKLIGESNVEVTLTGP--------
MMAR_5375|M.marinum_M APVTQPPPTGEP-EPVD--LGYRPATKELPFGQNISAVLISPPQAPAGTH
MUL_4995|M.ulcerans_Agy99 APVTQPPPTGEP-EPLD--LGYRPATKELPFGQNISAVLISPPQAPAGTH
Mb3841|M.bovis_AF2122/97 APITQPPAGRPPNDLLDSGLGYRPATKEQPFGQNISAILISPPQAPPGTQ
Rv3811|M.tuberculosis_H37Rv APITQPPAGRPPNDLLDSGLGYRPATKEQPFGQNISAILISPPQAPPGTQ
Mvan_5652|M.vanbaalenii_PYR-1 APPIGPAAAAHKPDGPA--LGYIPANVESPLPQNITAVLISPPQAPP-DL
MSMEG_2739|M.smegmatis_MC2_155 GARVVRGAINAAWDKLGGSAGVLGVPADDETYDGDVVRQKFTGGELSWNR
TH_1521|M.thermoresistible__bu GARVVRGAINLAWDRLGGSAGVLGVPAEDEAYRGDVVTQRFSGGEISWNR
MLBr_01002|M.leprae_Br4923 GAFVVRGALNAAWDKLGSSAGVLGVPVADESFDGEVISQKFSGGAVFWNK
. . . .
MAB_2560|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2699|M.avium_104 --------------------------------------------------
MMAR_5375|M.marinum_M WTPPTGVTMPGQAPPIISRADWGADEALRCESPEYDRAVRAAVVHHTAGS
MUL_4995|M.ulcerans_Agy99 WTPPTGVTMPGQAPPIISRADWGADEALRCESPEYDRTVRAAVVHQTAGS
Mb3841|M.bovis_AF2122/97 WTPPTAVTMAGQPPAIISRAEWGADESLRCETPEYDRGVRAAVVHHTAGS
Rv3811|M.tuberculosis_H37Rv WTPPTAVTMAGQPPAIISRAEWGADESLRCETPEYDRGVRAAVVHHTAGS
Mvan_5652|M.vanbaalenii_PYR-1 VPLPNAATPAGQPPRIINRVEWGADEGMRCGEPRYDTRIRAGVVHHTAGS
MSMEG_2739|M.smegmatis_MC2_155 KTKAFTTVPPELADQLKDLQIPDDPASAIAAARRAAGGPMGPLGAKDGDV
TH_1521|M.thermoresistible__bu KTREFSTVPPELADQLADLDVPQNPTAEINAARRAAGGALGPLGAKEGDE
MLBr_01002|M.leprae_Br4923 KSSEFTTEPTALAEQLTGLLVATDPTTAISMAWRAAGGVSGPLGPKQGGQ
MAB_2560|M.abscessus_ATCC_1997 --------------------------------IAAKYSSASESQKQALGK
MAV_2699|M.avium_104 --------------------------------IAAKYASATDDQKKALGK
MMAR_5375|M.marinum_M NDYSPLESAGIVKAIYTYHSKTLGWCDIAYNALVDKYGQIFEGSAGGLTK
MUL_4995|M.ulcerans_Agy99 NDYSPLESAGIVKAIYTYHSKTLGWCDIAYNALVDKYGQIFEGSAGGLTK
Mb3841|M.bovis_AF2122/97 NDYSPLESAGIVKAIYTYHSKTLGWCDIAYNALVDKYGQVFEGSAGGLTK
Rv3811|M.tuberculosis_H37Rv NDYSPLESAGIVKAIYTYHSKTLGWCDIAYNALVDKYGQVFEGSAGGLTK
Mvan_5652|M.vanbaalenii_PYR-1 NEYTPEDSAGIVRSIYEYHTRTLGWCDIAYNAMVDKYGQVFEGRAGGMNR
MSMEG_2739|M.smegmatis_MC2_155 YKIGDAGGLGQNFAGGKIFYSPETGANVISGQVLEKYESVGGPQG-DLGF
TH_1521|M.thermoresistible__bu YPIGDDG-VAQDFTGGTIFYSPATGAHVLTGQVLEKYRSVGGPEG-DLGF
MLBr_01002|M.leprae_Br4923 HPIGADG-IIQDFAGGKVFFSKATGANAVENDILAKYESLGGPVGSDLGF
: ** . :
MAB_2560|M.abscessus_ATCC_1997 PLTGDHNAGT----------------------------------------
MAV_2699|M.avium_104 PLTGDRNAGK----------------------------------------
MMAR_5375|M.marinum_M PVEGFHTGGFNRDTWGVAMIGN-------FDDVAPTPLQIRAVGRLLGWR
MUL_4995|M.ulcerans_Agy99 PVEGFHTGGFNRDAWGVAMIGN-------FDDVAPTPLQIRAVGRLLGWR
Mb3841|M.bovis_AF2122/97 PVEGFHTGGFNRNTWGVAMIGN-------FDDVAPTPIQIRTVGRLLGWR
Rv3811|M.tuberculosis_H37Rv PVEGFHTGGFNRNTWGVAMIGN-------FDDVAPTPIQIRTVGRLLGWR
Mvan_5652|M.vanbaalenii_PYR-1 PVEGAHTGGFNHNTWGVAMLGN-------FDVVPPTPIQLRNTATLLGWV
MSMEG_2739|M.smegmatis_MC2_155 PTSSEDEGGLGPNSRIATFAAPDKPVIFWTPDYGAVIVRGAMNAAWEKLG
TH_1521|M.thermoresistible__bu PISGEHDGGAG--GRMAGFAAADEPIIFWTPDYGAVIVRGAMKAAWDKLG
MLBr_01002|M.leprae_Br4923 PAANEGDGGIVTSSRIAIFSAADKPVIFWTPDHGAFVVRGAMKAAWDKLK
* . .*
MAB_2560|M.abscessus_ATCC_1997 --------------RESGAVFQQFQGGAIIAK-----------NNQAGTP
MAV_2699|M.avium_104 --------------RESGVVFQQFEGGVITAK-----------NDAPGTP
MMAR_5375|M.marinum_M LGIAEVDPKSMVELESTGSSYTTVPGGAIAKLPAIFTHRDVGNTDCPGNA
MUL_4995|M.ulcerans_Agy99 LGIAEVDPKSMVELESTGSSYTTVPGGAIAKLPAIFTHRDVGNTDCPGNA
Mb3841|M.bovis_AF2122/97 LGMDDVDPRSMVDLQSAGSSYTTFPGGAIARLPAIFTHRDVGNTDCPGNA
Rv3811|M.tuberculosis_H37Rv LGMDDVDPRSMVDLQSAGSSYTTFPGGAIARLPAIFTHRDVGNTDCPGNA
Mvan_5652|M.vanbaalenii_PYR-1 LGQAGVDPLATVVMPSEGGSFTKFPFGASPTLPTIFTHRDVGNTECPGNA
MSMEG_2739|M.smegmatis_MC2_155 GATGTLGAPTADQTEDGTVITQKFSGGAISWDRADNTFTTEPSNLASELA
TH_1521|M.thermoresistible__bu GAAGELGVPVDDQTEDGDEITQRFSGGSITWNRSDGSFRTEPAGLAAQLT
MLBr_01002|M.leprae_Br4923 GPNGKLGVPVADQSVDGNVISQRFIGGKISWNRANNTFTADPANLASLLS
. . * . .
MAB_2560|M.abscessus_ATCC_1997 AFIVVGKIR-----------------------------------------
MAV_2699|M.avium_104 AYITLGKIR-----------------------------------------
MMAR_5375|M.marinum_M AYALMDEIREIASHFNDPP-------------------------------
MUL_4995|M.ulcerans_Agy99 AYALMDEIREIASHFNDPP-------------------------------
Mb3841|M.bovis_AF2122/97 AYAVMDEIRDIAAHFNDPP-------------------------------
Rv3811|M.tuberculosis_H37Rv AYAVMDEIRDIAAHFNDPP-------------------------------
Mvan_5652|M.vanbaalenii_PYR-1 AYALMGQIRDIAARFNDPPGP-----------------------------
MSMEG_2739|M.smegmatis_MC2_155 GLQIPGAEQ-APPPAAEAPQAEDESKPFSWHWSWWWLVALIPVLLLAGLV
TH_1521|M.thermoresistible__bu GLEVPGVEPPADIEEAPLAQSEDGGGPSRPGVGVGWLLVLIPVLVLAAAL
MLBr_01002|M.leprae_Br4923 GLQVS--EQSQPSELAMLFHAKKSTG------HWWWLVAAVAVLLVIVMF
.
MAB_2560|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2699|M.avium_104 --------------------------------------------------
MMAR_5375|M.marinum_M --------------------------------------------------
MUL_4995|M.ulcerans_Agy99 --------------------------------------------------
Mb3841|M.bovis_AF2122/97 --------------------------------------------------
Rv3811|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_5652|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2739|M.smegmatis_MC2_155 VGAALWHRRRNRDDGFDHEPFDDDHYDDHYDDRHDDRYGDSYEDRYDDGP
TH_1521|M.thermoresistible__bu IGLTIWNRRR-RYAGAGHLQ------SGQYDPEHHD------SERYDPEH
MLBr_01002|M.leprae_Br4923 VLLALGWRRR----------------RTAHDIVADS-----HDHDMDVG-
MAB_2560|M.abscessus_ATCC_1997 -----------------------------------------DAWNIQRDA
MAV_2699|M.avium_104 -----------------------------------------EAWNVPRGA
MMAR_5375|M.marinum_M ----------------------EELLKSLEGGAIYQRWQELGAMNSVLGA
MUL_4995|M.ulcerans_Agy99 ----------------------EELLKSLEGGATYQRWQELGAMNSVLGA
Mb3841|M.bovis_AF2122/97 ----------------------EELIKALEGGAIYQRWQALGGMNSALGA
Rv3811|M.tuberculosis_H37Rv ----------------------EELIKALEGGAIYQRWQALGGMNSALGA
Mvan_5652|M.vanbaalenii_PYR-1 ----------------------EQLAETLRGGAIHAKWEALGGMNSYLGR
MSMEG_2739|M.smegmatis_MC2_155 HDDGPHDDRAPHTDYREGRFDADRYRDEDAAGVSDADPYAPGADTRADTL
TH_1521|M.thermoresistible__bu HDSE--------------RYDPERY--DQGPDAFDSDVHDPGGYDTREDL
MLBr_01002|M.leprae_Br4923 -------------------MDFGYKAAVDGQCTYDAES---GTEHPVRDV
MAB_2560|M.abscessus_ATCC_1997 DGTPSITGNNGS--------------------------------------
MAV_2699|M.avium_104 DGTPEITGTNGS--------------------------------------
MMAR_5375|M.marinum_M PTSPEADGADGARY------------------------------------
MUL_4995|M.ulcerans_Agy99 PTSPEADGAGGARY------------------------------------
Mb3841|M.bovis_AF2122/97 PTSPEADAADGARY------------------------------------
Rv3811|M.tuberculosis_H37Rv PTSPEADAADGARY------------------------------------
Mvan_5652|M.vanbaalenii_PYR-1 PTSPEASGEGATRY------------------------------------
MSMEG_2739|M.smegmatis_MC2_155 DDAVTSRFADPYHENETAGSPFDGPTDVSMPISQWAAPGDRPGEDQPENP
TH_1521|M.thermoresistible__bu DRRHETLSGDAAPQ-----------------------PSELFGLGTP---
MLBr_01002|M.leprae_Br4923 ERGPTVSWLRGAQD--------------------------ATG-------
MAB_2560|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2699|M.avium_104 --------------------------------------------------
MMAR_5375|M.marinum_M -------------------------ATFAKGAMYWSPTTGAQPVTGAIYD
MUL_4995|M.ulcerans_Agy99 -------------------------ATFAKGVMYWSSTTGAQPVTGAIYD
Mb3841|M.bovis_AF2122/97 -------------------------ATFAKGAMYWSPVTDAQPITGAIYE
Rv3811|M.tuberculosis_H37Rv -------------------------ATFAKGAMYWSPVTDAQPITGAIYE
Mvan_5652|M.vanbaalenii_PYR-1 -------------------------VTFEHGAVYWSPESGAEPVTGELYN
MSMEG_2739|M.smegmatis_MC2_155 EEPAQRDDFGDDFYHAEDDAFERDEADDEFDDDREDDDFDTDEDLADRAD
TH_1521|M.thermoresistible__bu --PAQADFRG--WGYTGDPATPADEARTATPPGELGDKAPPEPHRADSAS
MLBr_01002|M.leprae_Br4923 --LAQDARLG--------PAFGSELPSESEEPLGLEED-DPDAVDTDSMP
MAB_2560|M.abscessus_ATCC_1997 -------------------------------------AGPLGLPTSDENT
MAV_2699|M.avium_104 -------------------------------------AGPLGLPVSDQSS
MMAR_5375|M.marinum_M AWAS-----------------------------LSYERGPLGLPTSAEIQ
MUL_4995|M.ulcerans_Agy99 AWAS-----------------------------LSYERGPLGLPTSAEIQ
Mb3841|M.bovis_AF2122/97 AWAS-----------------------------QSYERGPLGLPTSAEIQ
Rv3811|M.tuberculosis_H37Rv AWAS-----------------------------QSYERGPLGLPTSAEIQ
Mvan_5652|M.vanbaalenii_PYR-1 AWGS-----------------------------LGFERGALGLPTSAEIP
MSMEG_2739|M.smegmatis_MC2_155 VEADLEDDLEDDYEDDYEDDLDEETSGGAGAGTAAAGAAAAAAAAASTFG
TH_1521|M.thermoresistible__bu AESG-----------------QTRTTAAATGGAETLGAPPDQLPGQDEST
MLBr_01002|M.leprae_Br4923 ALSD------------------ADFPYAALSDAAHWDADAAEVVATDNSS
.
MAB_2560|M.abscessus_ATCC_1997 EGDQLVSTFEHGKIEYNAKSGEVAVTVNGKVVPSGL--------------
MAV_2699|M.avium_104 VGDVLVSNFEHGTIQYNPKTDQVAVTVNGKVVPSGL--------------
MMAR_5375|M.marinum_M EPLRITQNFQHGVLNFQRLTGNVSEVVNGITTPLATKPPS----------
MUL_4995|M.ulcerans_Agy99 EPLRITQNFQHGVLNFQRLTGNVSEVVNGITTPLATKPPS----------
Mb3841|M.bovis_AF2122/97 EPLQITQNFQHGTLNFERLTGNVTEVVDGITTPLATRPPS----------
Rv3811|M.tuberculosis_H37Rv EPLQITQNFQHGTLNFERLTGNVTEVVDGITTPLATRPPS----------
Mvan_5652|M.vanbaalenii_PYR-1 EPLWIVQNFQHGTLNFDRETGAVTRVIDGVPVELPPPGAD----------
MSMEG_2739|M.smegmatis_MC2_155 GPVPVGAGFNRPALEEQEDPDNVDTAPTRVVTPADLRSDP--------PS
TH_1521|M.thermoresistible__bu EPERETPSED-PFFEK--DQDDVDTAPTPIVAPEAAEPRPSATRPDSETT
MLBr_01002|M.leprae_Br4923 ------VATDNSSLLETAADTEVSTGRHAAVDMADAMDAS-------FPG
: : *
MAB_2560|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2699|M.avium_104 --------------------------------------------------
MMAR_5375|M.marinum_M ------------------------GPMVPPEHFSLPIHPIIP--------
MUL_4995|M.ulcerans_Agy99 ------------------------GPMVPPEHFSLPIHPIIP--------
Mb3841|M.bovis_AF2122/97 ------------------------GPTVPPEHFTLPTHPIT---------
Rv3811|M.tuberculosis_H37Rv ------------------------GPTVPPEHFTLPTHPIT---------
Mvan_5652|M.vanbaalenii_PYR-1 ------------------------STPVQLERFTPPSNPA----------
MSMEG_2739|M.smegmatis_MC2_155 GRHAAIEFDEPIPSATALHLPLD-DPQEAPDGYPIKADTKTGMYWAPDSA
TH_1521|M.thermoresistible__bu GRHAAIDVDEPEYGQTALRLPADGDPRRPPEGYPIKARITDGLYWVPGSA
MLBr_01002|M.leprae_Br4923 VTVPRMLFRPSPTLRPTIHLPLD-DPYQVPDGYPIKASPRFGLYYTPASE
MAB_2560|M.abscessus_ATCC_1997 --------------------------
MAV_2699|M.avium_104 --------------------------
MMAR_5375|M.marinum_M --------------------------
MUL_4995|M.ulcerans_Agy99 --------------------------
Mb3841|M.bovis_AF2122/97 --------------------------
Rv3811|M.tuberculosis_H37Rv --------------------------
Mvan_5652|M.vanbaalenii_PYR-1 --------------------------
MSMEG_2739|M.smegmatis_MC2_155 DYEDAVAEIWFASEEFARTNGFVRAN
TH_1521|M.thermoresistible__bu DYDEVDAEIWFASEELARTNGFVRSD
MLBr_01002|M.leprae_Br4923 LYHDTLAEVWLANEEIAQVNGFIKAD