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KTTAHRRSAVVGLAAVALITVGCSNGKSVDASAPPHAAASATSTSANPAQPTEVKLIGESNVEVTLTGPI AAKYASATDDQKKALGKPLTGDRNAGKRESGVVFQQFEGGVITAKNDAPGTPAYITLGKIREAWNVPRGA DGTPEITGTNGSAGPLGLPVSDQSSVGDVLVSNFEHGTIQYNPKTDQVAVTVNGKVVPSGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2699 | - | - | 100% (202) | hypothetical protein MAV_2699 |
| M. avium 104 | MAV_1082 | - | 4e-22 | 36.36% (198) | hypothetical protein MAV_1082 |
| M. avium 104 | MAV_3615 | - | 8e-05 | 28.57% (126) | hypothetical protein MAV_3615 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3841 | - | 3e-05 | 28.69% (122) | hypothetical protein Mb3841 |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv3811 | - | 3e-05 | 28.69% (122) | hypothetical protein Rv3811 |
| M. leprae Br4923 | MLBr_01002 | - | 4e-06 | 27.42% (124) | hypothetical protein MLBr_01002 |
| M. abscessus ATCC 19977 | MAB_2560 | - | 7e-78 | 70.30% (202) | hypothetical protein MAB_2560 |
| M. marinum M | MMAR_1991 | - | 8e-07 | 30.58% (121) | hypothetical protein MMAR_1991 |
| M. smegmatis MC2 155 | MSMEG_6406 | - | 7e-05 | 30.34% (89) | N-acetylmuramoyl-L-alanine amidase |
| M. thermoresistible (build 8) | TH_1521 | - | 9e-07 | 31.15% (122) | POSSIBLE CONSERVED TRANSMEMBRANE ALANINE AND GLYCINE RICH |
| M. ulcerans Agy99 | MUL_3364 | - | 2e-07 | 31.40% (121) | hypothetical protein MUL_3364 |
| M. vanbaalenii PYR-1 | Mvan_2440 | - | 5e-05 | 26.72% (131) | LGFP repeat-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2699|M.avium_104 -----------------------------MKTTAHRRSAVVGLAAVALIT
MAB_2560|M.abscessus_ATCC_1997 -----------------------------MRTIAIRHRAVIGLSAVALIT
TH_1521|M.thermoresistible__bu MNGQWARTETALGRFAACLLAVATMTLAGLLSAPEAAATPEEDAGAAIGA
Mvan_2440|M.vanbaalenii_PYR-1 MSRQPMLRRRLVGRLTIGLLGVATA----LLLAPHATAQPEVEANDAITA
MMAR_1991|M.marinum_M MNGQRGQLSRLIGR---ALLSLAASVVAVTLLAPTATASPIGDAEAAMME
MUL_3364|M.ulcerans_Agy99 MNGQRGQLSRLIGR---ALLSLAASVVAVTWLAPTATASPIGDAEAAMME
MLBr_01002|M.leprae_Br4923 -------MSKRVRR---ALANTATTAVVTVLLAPVVTASPTGDADDAITA
Mb3841|M.bovis_AF2122/97 -----------------MAATVVIVAWIANRPPASSHEPSPTPNTQLAEQ
Rv3811|M.tuberculosis_H37Rv -----------------MAATVVIVAWIANRPPASSHEPSPTPNTQLAEQ
MSMEG_6406|M.smegmatis_MC2_155 ---MQSRRPAPSILFTAIAATLIVVPWALSGTGDEHHNP-AADAPSLTQQ
MAV_2699|M.avium_104 VGCSNGKSVDASAPPHAAASATSTSANPAQPTEVKLIGESNVEVTLTGPI
MAB_2560|M.abscessus_ATCC_1997 VGCSNGTSVDVPSP-EVGLIATTSSAAPAQPAEVKLIGERDVEVTLTGPI
TH_1521|M.thermoresistible__bu AYDASGGPGGPLGPPDGGVYPIGAGFAQNYAHGKMFFTPQTGAHFMQGEI
Mvan_2440|M.vanbaalenii_PYR-1 AWQSSGGDTGPLGPRSGDVYPVGSGFAQNFASGRMFFTPATGAHFMQGAI
MMAR_1991|M.marinum_M AWDKAGGDTSTLGARKGDVYPVGDGFALDFDGGKMFFTPQTGAKYMYGPI
MUL_3364|M.ulcerans_Agy99 AWDKAGGDTSTLGARKGDVYPVGDGFALDFDGGKMFFTPQTGAKYMYGPI
MLBr_01002|M.leprae_Br4923 AWHKAGGDNSVLGAKKGEVYPLGDGFAQNFASGKLFFTTATGAKLLYGPV
Mb3841|M.bovis_AF2122/97 PLIGLGGGVTVRELTQDTPFSLVALTG-DLAGTSARVRAKRPDGDWGPWY
Rv3811|M.tuberculosis_H37Rv PLIGLGGGVTVRELTQDTPFSLVALTG-DLAGTSARVRAKRPDGDWGPWY
MSMEG_6406|M.smegmatis_MC2_155 PLDDLGGGETIREIHQDEPFSLVALTAHDLDGTSARIRAKKADGSWGPWY
* . .
MAV_2699|M.avium_104 AAKYASAT-DDQKKALGKPLTGDR--------------------------
MAB_2560|M.abscessus_ATCC_1997 AAKYSSAS-ESQKQALGKPLTGDH--------------------------
TH_1521|M.thermoresistible__bu LAKYESLG-GPADSDLGFPTLSESPGRVGPDSRNVIFSAPDRPVIFWTPD
Mvan_2440|M.vanbaalenii_PYR-1 LEKYDSLG-GPADSDLGFPTIDEGPGRA-PESRNSTFSAADNPVIFWTPA
MMAR_1991|M.marinum_M LAKYDELG-GPADSDLGFPTINEVPGLAGPDSRVSTFSASDNPVIFWTPD
MUL_3364|M.ulcerans_Agy99 LAKYDELG-GPADSDLGFPTINEVPGLAGPDSRVSTFSASDNPVIFWTPD
MLBr_01002|M.leprae_Br4923 LGKYESLG-GPVNSDLGFPIIDEVPGLAGPDSRVSIFAASDNPVIFWTPD
Mb3841|M.bovis_AF2122/97 QTEYETEPRDPAGTDGSVELGGLNPGPR-----------STDPVFVGTTT
Rv3811|M.tuberculosis_H37Rv QTEYETEPRDPAGTDGSVELGGLNPGPR-----------STDPVFVGTTT
MSMEG_6406|M.smegmatis_MC2_155 ----EAEALDGVGAD--------TPGPR-----------GTDPVFVGRTN
MAV_2699|M.avium_104 ----------------------------NAGKRESGVVFQQFEGG-----
MAB_2560|M.abscessus_ATCC_1997 ----------------------------NAGTRESGAVFQQFQGG-----
TH_1521|M.thermoresistible__bu TGARVVRGAINLAWDRLGGSAGVLGVPAEDEAYRGDVVTQRFSGGEISWN
Mvan_2440|M.vanbaalenii_PYR-1 TGARVVRGPINAAWDKLGGSSGVLGVPAEDETYDGSVVTQKFTGGELSYD
MMAR_1991|M.marinum_M HGAFVVRGAMNAAWDKLGSSGGVLGAPIGDATFDGEVTSQKFTGGEVSWN
MUL_3364|M.ulcerans_Agy99 HGAFVVRGAMNAPWDKLGSSGGVLGAPIGDATFDGEVTSQKFTGGEVSWN
MLBr_01002|M.leprae_Br4923 HGAFVVRGALNAAWDKLGSSAGVLGVPVADESFDGEVISQKFSGGAVFWN
Mb3841|M.bovis_AF2122/97 TVQVAVTRPIDAPITQPPAGRPPNDLLDSGLGYRPATKEQPFGQN-----
Rv3811|M.tuberculosis_H37Rv TVQVAVTRPIDAPITQPPAGRPPNDLLDSGLGYRPATKEQPFGQN-----
MSMEG_6406|M.smegmatis_MC2_155 TVQIAITRPENAAPTAP-APKNKDDKNKPDLGYRPATVQQPLGQN-----
. * : .
MAV_2699|M.avium_104 ----------------------------VITAKNDAPG------------
MAB_2560|M.abscessus_ATCC_1997 ----------------------------AIIAKNNQAG------------
TH_1521|M.thermoresistible__bu RKTREFSTVPPELADQLADLDVPQNPTAEINAARRAAGGALGPLGAKEGD
Mvan_2440|M.vanbaalenii_PYR-1 SGAKTFTTVPPELAGQLTDLSIPDDPIAAINAARRAAGGARGPLGAAEGD
MMAR_1991|M.marinum_M RQTKEFTTTPTVLADQLKDLQVAIDPTAAINMAWRAAGGATGPLGARKGA
MUL_3364|M.ulcerans_Agy99 RQTKEFTTTPTVLADQLKDLQVAIDPTAAINMAWRAAGGATGPLGARRGA
MLBr_01002|M.leprae_Br4923 KKSSEFTTEPTALAEQLTGLLVATDPTTAISMAWRAAGGVSGPLGPKQGG
Mb3841|M.bovis_AF2122/97 -ISAILISPPQAPPGTQWTPPTAVTMAGQPPAIISRAEWGADESLRCETP
Rv3811|M.tuberculosis_H37Rv -ISAILISPPQAPPGTQWTPPTAVTMAGQPPAIISRAEWGADESLRCETP
MSMEG_6406|M.smegmatis_MC2_155 -VTAVLISPPQAP-ADIGPLPTAVTAPGVPPHIIGRAQWGADESMRCP-A
.
MAV_2699|M.avium_104 -----------------------TPAYITLGKIREAWNVPRGADG-----
MAB_2560|M.abscessus_ATCC_1997 -----------------------TPAFIVVGKIRDAWNIQRDADG-----
TH_1521|M.thermoresistible__bu EYPIGDDGVAQDFTGGTIFYSPATGAHVLTGQVLEKYRSVGGPEG-DLGF
Mvan_2440|M.vanbaalenii_PYR-1 PYEIGSDGMGQDFVNGAIFYSPETGANVVTGQVLAKYQSVGGPEG-DLGF
MMAR_1991|M.marinum_M QYPIGGDGIAQDFEGGKVFFSPATGANAVEGEILAKYESLGGPVSSDLGF
MUL_3364|M.ulcerans_Agy99 QYPIGGDGIAQDFEGGKVFFSPATGANAVEGEILAKYESLGGPVSSDLGF
MLBr_01002|M.leprae_Br4923 QHPIGADGIIQDFAGGKVFFSKATGANAVENDILAKYESLGGPVGSDLGF
Mb3841|M.bovis_AF2122/97 EYDRGVRAAVVHHTAGSNDYSPLESAGIVKAIYTYHSKTLG---------
Rv3811|M.tuberculosis_H37Rv EYDRGVRAAVVHHTAGSNDYSPLESAGIVKAIYTYHSKTLG---------
MSMEG_6406|M.smegmatis_MC2_155 VYDAGIRAGIVHHTAGSNDYAPEDSAGIVRSIYEYHTRTLG---------
* .
MAV_2699|M.avium_104 ------------------------------------------TPEITGTN
MAB_2560|M.abscessus_ATCC_1997 ------------------------------------------TPSITGNN
TH_1521|M.thermoresistible__bu PISGEHDGGAG--GRMAGFAAADEPIIFWTPDYGAVIVRGAMKAAWDKLG
Mvan_2440|M.vanbaalenii_PYR-1 PITSEADGGLAPASRISSFAAEDKPVIFWTPDHGAVIVRGAMNAAWQKLG
MMAR_1991|M.marinum_M PTANESDGGIEPASRVAAFSAADKPVIFWTPDHGAFVVRGAMKVAWDKLK
MUL_3364|M.ulcerans_Agy99 PTANESDGGIEPASRVAAFSAADKPVIFWTPDHGAFVVRGAMKVAWDKFK
MLBr_01002|M.leprae_Br4923 PAANEGDGGIVTSSRIAIFSAADKPVIFWTPDHGAFVVRGAMKAAWDKLK
Mb3841|M.bovis_AF2122/97 --------------------------------WCDIAYNALVDKYGQVFE
Rv3811|M.tuberculosis_H37Rv --------------------------------WCDIAYNALVDKYGQVFE
MSMEG_6406|M.smegmatis_MC2_155 --------------------------------WCDIAYNALVDKYGQVFE
MAV_2699|M.avium_104 GSAGPLGLPVSDQSSVGDVLVSNFEHGTIQYNPKTD------------QV
MAB_2560|M.abscessus_ATCC_1997 GSAGPLGLPTSDENTEGDQLVSTFEHGKIEYNAKSG------------EV
TH_1521|M.thermoresistible__bu GAAGELGVPVDDQTEDGDEITQRFSGGSITWNRSDGSFRTEPAGLAAQLT
Mvan_2440|M.vanbaalenii_PYR-1 GATGELGAPVADQTQNGDVITQRFNGGALSWDTATKKFSTEPAGLAPQLA
MMAR_1991|M.marinum_M GATGKLGAPVADQTEAGDVVSQKFTGGTISWNRATNSFSTDPANLAPLLS
MUL_3364|M.ulcerans_Agy99 GATGKLGAPVADQTEVGDVVSQKFTGGTISWNRATNSFSTDPANLAPLLS
MLBr_01002|M.leprae_Br4923 GPNGKLGVPVADQSVDGNVISQRFIGGKISWNRANNTFTADPANLASLLS
Mb3841|M.bovis_AF2122/97 GSAGGLTKPVEGFHTGG--FNRNTWGVAMIGNFDDVAPTPIQIRTVGRLL
Rv3811|M.tuberculosis_H37Rv GSAGGLTKPVEGFHTGG--FNRNTWGVAMIGNFDDVAPTPIQIRTVGRLL
MSMEG_6406|M.smegmatis_MC2_155 GRAGGMDRPVEGAHTGG--FNRDTWGVAMMGNFDAVPPTPIQLRTTGRLL
* * : *. . * . : :
MAV_2699|M.avium_104 AVTVNGKVVPSGL-------------------------------------
MAB_2560|M.abscessus_ATCC_1997 AVTVNGKVVPSGL-------------------------------------
TH_1521|M.thermoresistible__bu GLEVPGVEPPADIEEAPLAQSEDGGGPSRPGVGVGWLLVLIPVLVLAAAL
Mvan_2440|M.vanbaalenii_PYR-1 GLEVPGAEPPQAPPQS-QSQASENSESSGLKWTWWWLLAIVPVLLLAG-L
MMAR_1991|M.marinum_M GLQVSGQNQPSTSAAPPHSKKFT--------WHWWWLAAAIPVLLLVVFL
MUL_3364|M.ulcerans_Agy99 GLQVSGQNQPSTSAAPPHSKKFT--------WHWWWLAAAIPVLLLVVFL
MLBr_01002|M.leprae_Br4923 GLQVSEQSQPSELAMLFHAKKST--------GHWWWLVAAVAVLLVIVMF
Mb3841|M.bovis_AF2122/97 GWRLGMDDVDPRSMVDLQSAGSS-----------YTTFPGGAIARLPAIF
Rv3811|M.tuberculosis_H37Rv GWRLGMDDVDPRSMVDLQSAGSS-----------YTTFPGGAIARLPAIF
MSMEG_6406|M.smegmatis_MC2_155 GWRLGLDRIDPHGTVVLASEGGS-----------FTHFPRGATPTLPAIF
. :
MAV_2699|M.avium_104 --------------------------------------------------
MAB_2560|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1521|M.thermoresistible__bu IGLTIWNRRRRYAGAGHLQSGQYDPEHHDSERYDPEHHDSERYDPERYDQ
Mvan_2440|M.vanbaalenii_PYR-1 AAFAVLRTRGRRGGGDELFGVPGETGHDYAPALAGEGGGGVR------DD
MMAR_1991|M.marinum_M VVMAVGLRRRR---AGQETHGYEPAEQDAESGYDAIGGQWPHDELDFGSE
MUL_3364|M.ulcerans_Agy99 VVMAVGLRRRR---AGQETHGYEPAEHDAESGYDAIGGQWPHDELDFGSE
MLBr_01002|M.leprae_Br4923 VLLALGWRRRR---TAHDIVADS-HDHDMDVGMDFGYKAAVDGQCTYDAE
Mb3841|M.bovis_AF2122/97 THRDVGNTDCP----GNAAYAVMDEIRDIAAHFNDPP-------------
Rv3811|M.tuberculosis_H37Rv THRDVGNTDCP----GNAAYAVMDEIRDIAAHFNDPP-------------
MSMEG_6406|M.smegmatis_MC2_155 THRDVGNTDCP----GNAAYAEMGRLRDIAARFNQPPG------------
MAV_2699|M.avium_104 --------------------------------------------------
MAB_2560|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1521|M.thermoresistible__bu GP-DAFDSDVHDPGGYDTREDLDRRHETLS-GDAAPQPSELFGLGTPPAQ
Mvan_2440|M.vanbaalenii_PYR-1 GPEDALFGDRYAREGIGSLASATPVPSSST-EDFHPDPSTFWGV------
MMAR_1991|M.marinum_M HFPPDDHDLAHAASDSGAGARVSWPRGGGG-PAYGEEMPPSFHEDFERDE
MUL_3364|M.ulcerans_Agy99 HFPPDDHDLAHAASDSGTGARVSWPRGGGGGPAYGEEMPPSFHEDFERDE
MLBr_01002|M.leprae_Br4923 SG------TEHPVRDVERGPTVSWLRGAQD--ATGLAQDARLGPAFG-SE
Mb3841|M.bovis_AF2122/97 ---------EELIKALEGGAIYQRWQALGG--------------------
Rv3811|M.tuberculosis_H37Rv ---------EELIKALEGGAIYQRWQALGG--------------------
MSMEG_6406|M.smegmatis_MC2_155 --------PEELAEQMRGGAIFARWESVGG--------------------
MAV_2699|M.avium_104 --------------------------------------------------
MAB_2560|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1521|M.thermoresistible__bu ADFRGWGYTGDPATPADEARTATPPGELGDKAPPEPHRADSASAESGQTR
Mvan_2440|M.vanbaalenii_PYR-1 ------------------------PAGGGDTGP-----------ELGERE
MMAR_1991|M.marinum_M FAHEDFEHEDFEDEDFEHENFEHEDFGADDEDPD--AVDTTPTPVISIAD
MUL_3364|M.ulcerans_Agy99 FAHEDFEHEDFEDEDFEHENFEHEDFGADDEDPD--AVDTTPTPVISIAD
MLBr_01002|M.leprae_Br4923 LPSE-----------------SEEPLGLEEDDPD--AVDTDSMPALSDAD
Mb3841|M.bovis_AF2122/97 -----------------------------------------MNSALGAPT
Rv3811|M.tuberculosis_H37Rv -----------------------------------------MNSALGAPT
MSMEG_6406|M.smegmatis_MC2_155 -----------------------------------------PAGPLGNPT
MAV_2699|M.avium_104 --------------------------------------------------
MAB_2560|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1521|M.thermoresistible__bu TTAAATGGAETLGAPPDQLPGQDESTE-----------------------
Mvan_2440|M.vanbaalenii_PYR-1 QQVGEQENPDTVDTAPTRVLTPEEPTV-----------------------
MMAR_1991|M.marinum_M LAEAVRQETAVPETAVTEAFGLPHRYVPEPVVPETAAPEAAVPETAVHED
MUL_3364|M.ulcerans_Agy99 LAEAVRQETAVPETAVTEAFGLPHRYVPEPVVPETAAPEAAVPETAVHGD
MLBr_01002|M.leprae_Br4923 FPYAALSDAAHWDADAAEVVATDN--------------------------
Mb3841|M.bovis_AF2122/97 SPEADAADGARYATFAKGAMYWSPVTD-----------------------
Rv3811|M.tuberculosis_H37Rv SPEADAADGARYATFAKGAMYWSPVTD-----------------------
MSMEG_6406|M.smegmatis_MC2_155 SPEAAAEGEARYATFERGAIYWSPVTG-----------------------
MAV_2699|M.avium_104 --------------------------------------------------
MAB_2560|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1521|M.thermoresistible__bu -----------PERETPSEDPFFEKDQDDVDTAPTPIVAPEAAEPRPSAT
Mvan_2440|M.vanbaalenii_PYR-1 -----------DDGE--VEDVTQATEALDIDRE--PLLPPDIES--VVAP
MMAR_1991|M.marinum_M DFPKSFMPGGGTADATTEIRVLPEAAGSPRPPRAGRHAAAETVEDDSEDE
MUL_3364|M.ulcerans_Agy99 DFPKSFMPGGGTADATTEIRVLPEAAGSPRPPRAGRHAAAETAEDDSEDE
MLBr_01002|M.leprae_Br4923 -----------SSVATDNSSLLETAADTEVS--TGRHAAVDMA-----DA
Mb3841|M.bovis_AF2122/97 -----------AQPITGAIYEAWASQSYERGPLGLPTSAEIQEPLQITQN
Rv3811|M.tuberculosis_H37Rv -----------AQPITGAIYEAWASQSYERGPLGLPTSAEIQEPLQITQN
MSMEG_6406|M.smegmatis_MC2_155 -----------AQPLTGAIYEAWGRLGFERGALGLPTSGEIHEPLWIKQN
MAV_2699|M.avium_104 --------------------------------------------------
MAB_2560|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1521|M.thermoresistible__bu RPDSET-TGRHAAIDVDEPEYGQTALRLPADGDPRRPPEGYPIKARITDG
Mvan_2440|M.vanbaalenii_PYR-1 APDSMTDTGRHARIDIDEPMPLGTALHMPFD-DPDEVPEGYPVKADTKTG
MMAR_1991|M.marinum_M VTVHARQAHAPAAAAAGPSAGARPTIHMPLDHDPYQAPEGYPIKASARFG
MUL_3364|M.ulcerans_Agy99 VTVHARQAHAPAAAAAGPSAGARPTIHMPLDHDPYQAPEGYPVKASARFG
MLBr_01002|M.leprae_Br4923 MDASFPGVTVPRMLFR-PSPTLRPTIHLPLD-DPYQVPDGYPIKASPRFG
Mb3841|M.bovis_AF2122/97 FQHGTLNFERLTGNVTEVVDGITTPLATRPPSGPTVPPEHFTLPTHPIT-
Rv3811|M.tuberculosis_H37Rv FQHGTLNFERLTGNVTEVVDGITTPLATRPPSGPTVPPEHFTLPTHPIT-
MSMEG_6406|M.smegmatis_MC2_155 FQHGTLNFDREKHTVVRVIDGVPQELPPAAPDDQPVQLERFT----PIA-
MAV_2699|M.avium_104 ----------------------------------
MAB_2560|M.abscessus_ATCC_1997 ----------------------------------
TH_1521|M.thermoresistible__bu LYWVPGSADYDEVDAEIWFASEELARTNGFVRSD
Mvan_2440|M.vanbaalenii_PYR-1 LYWTPESDDYHEAPVEIWFATEEIARTNGFVRGE
MMAR_1991|M.marinum_M LYYTPSSALYYDTLAEIWFATEAAAQANGFIKAD
MUL_3364|M.ulcerans_Agy99 LYYTPSSALYYDTLAEIWFATEAAAQANGFIKAD
MLBr_01002|M.leprae_Br4923 LYYTPASELYHDTLAEVWLANEEIAQVNGFIKAD
Mb3841|M.bovis_AF2122/97 ----------------------------------
Rv3811|M.tuberculosis_H37Rv ----------------------------------
MSMEG_6406|M.smegmatis_MC2_155 ----------------------------------