For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VPSRSRAPTMLLTAIAATVVIVSWVLTRPPPSTHEQPSAQDTRLVEQPLVGLGGGVTVRQLTQDEPFSLV ALTGDLVGTSARMRARQSDGSWGPWYQAEYETAAPDEQGAGAPATAGTSERPRSTEPVFVGTTNTVEIAV TRPIDAPVTQPPPTGEPEPVDLGYRPATKELPFGQNISAVLISPPQAPAGTHWTPPTGVTMPGQAPPIIS RADWGADEALRCESPEYDRAVRAAVVHHTAGSNDYSPLESAGIVKAIYTYHSKTLGWCDIAYNALVDKYG QIFEGSAGGLTKPVEGFHTGGFNRDTWGVAMIGNFDDVAPTPLQIRAVGRLLGWRLGIAEVDPKSMVELE STGSSYTTVPGGAIAKLPAIFTHRDVGNTDCPGNAAYALMDEIREIASHFNDPPEELLKSLEGGAIYQRW QELGAMNSVLGAPTSPEADGADGARYATFAKGAMYWSPTTGAQPVTGAIYDAWASLSYERGPLGLPTSAE IQEPLRITQNFQHGVLNFQRLTGNVSEVVNGITTPLATKPPSGPMVPPEHFSLPIHPIIP
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_5375 | - | - | 100% (550) | hypothetical protein MMAR_5375 |
M. marinum M | MMAR_1991 | - | 4e-09 | 29.71% (138) | hypothetical protein MMAR_1991 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3841 | - | 0.0 | 80.48% (538) | hypothetical protein Mb3841 |
M. gilvum PYR-GCK | Mflv_1157 | - | 1e-178 | 57.04% (547) | LGFP repeat-containing protein |
M. tuberculosis H37Rv | Rv3811 | - | 0.0 | 80.48% (538) | hypothetical protein Rv3811 |
M. leprae Br4923 | MLBr_01002 | - | 2e-07 | 28.12% (128) | hypothetical protein MLBr_01002 |
M. abscessus ATCC 19977 | MAB_0168c | - | 1e-141 | 48.40% (562) | putative N-acetymuramoyl-L-alanine amidase |
M. avium 104 | MAV_0206 | - | 0.0 | 76.78% (547) | N-acetylmuramoyl-L-alanine amidase |
M. smegmatis MC2 155 | MSMEG_6406 | - | 0.0 | 59.78% (547) | N-acetylmuramoyl-L-alanine amidase |
M. thermoresistible (build 8) | TH_0898 | csp | 1e-47 | 57.50% (160) | CONSERVED HYPOTHETICAL PROTEIN |
M. ulcerans Agy99 | MUL_4995 | - | 0.0 | 98.34% (541) | hypothetical protein MUL_4995 |
M. vanbaalenii PYR-1 | Mvan_5652 | - | 1e-179 | 57.53% (551) | LGFP repeat-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_5375|M.marinum_M ------MPSRSRAPTMLLTAIAATVVIVSWVLTRPPP------STHEQPS MUL_4995|M.ulcerans_Agy99 ---------------MLLTAIAATVVIVSWVLTRPPP------STHEQPS Mb3841|M.bovis_AF2122/97 --------------------MAATVVIVAWIANRPPA------SSHEPSP Rv3811|M.tuberculosis_H37Rv --------------------MAATVVIVAWIANRPPA------SSHEPSP MAV_0206|M.avium_104 -------MSRSRAPTTLLTAIAATVVLVSWVGDATRDR-----GAAGAPP Mflv_1157|M.gilvum_PYR-GCK ------MLYPRHAPSVLFTALAATVMLLPWAISGIPD-------GDEKPT Mvan_5652|M.vanbaalenii_PYR-1 ------MLYRRPAPSILFTALAATVVMLPWAISGGPD-------GDDSPA MSMEG_6406|M.smegmatis_MC2_155 ------MQSRRPAPSILFTAIAATLIVVPWALSGTGD-------EHHNPA TH_0898|M.thermoresistible__bu -------------------------------------------------- MAB_0168c|M.abscessus_ATCC_199 MRVSKMPVRRQLALAVAATATVMTVSVVDHIKSGQAEETAITSQSLQNAA MLBr_01002|M.leprae_Br4923 ----MSKRVRRALANTATTAVVTVLLAPVVTASPTGDADDAITAAWHKAG MMAR_5375|M.marinum_M AQDTRLVEQPLVGLGGGVTVRQLTQDEPFSLVALTG-DLVGTSARMRARQ MUL_4995|M.ulcerans_Agy99 AQDTRLVEQPLVGLGGGVTVRQLTQDEPFSLVALTG-DLVGTSARMRARQ Mb3841|M.bovis_AF2122/97 TPNTQLAEQPLIGLGGGVTVRELTQDTPFSLVALTG-DLAGTSARVRAKR Rv3811|M.tuberculosis_H37Rv TPNTQLAEQPLIGLGGGVTVRELTQDTPFSLVALTG-DLAGTSARVRAKR MAV_0206|M.avium_104 ARGTQLTEQPLIGLGAGVTVREISQQTPFSLVALTG-DLAGTSTRVRARR Mflv_1157|M.gilvum_PYR-GCK AGAPLLVQQPLTDLGGGETIRELHQDTPFSMVALTSADLTGTSARVRAKK Mvan_5652|M.vanbaalenii_PYR-1 MPAPQLAQQPLADLGGGESIRELHQDTPFSMVALTSEDFAGTSARVRAKK MSMEG_6406|M.smegmatis_MC2_155 ADAPSLTQQPLDDLGGGETIREIHQDEPFSLVALTAHDLDGTSARIRAKK TH_0898|M.thermoresistible__bu -------------------------------------------------- MAB_0168c|M.abscessus_ATCC_199 THDVLTSEVGLPGPSTPATVHDIQQADSFSLIAVRGEDLSSLDVSVRAQQ MLBr_01002|M.leprae_Br4923 GDNSVLGAKKGEVYPLGDGFAQNFASGKLFFTTATGAKLLYGPVLGKYES MMAR_5375|M.marinum_M SDGSWGPWYQAEYETAAPDEQG-AGAPATAGTSERP---RSTEPVFVGTT MUL_4995|M.ulcerans_Agy99 SDGSWGPWYQAEYETAAPDEQG-AGAPATAGTSERP---RSTEPVFVGTT Mb3841|M.bovis_AF2122/97 PDGDWGPWYQTEYETEPRDPAGTDGSVELGGLNPGP---RSTDPVFVGTT Rv3811|M.tuberculosis_H37Rv PDGDWGPWYQTEYETEPRDPAGTDGSVELGGLNPGP---RSTDPVFVGTT MAV_0206|M.avium_104 RDGSWGPWYQTEYETAAPDPGH------AGEATEGP---RGTDPVFVGTT Mflv_1157|M.gilvum_PYR-GCK DDGSWGQWYDVEPLEG------------VGADTPSPGGIRGTDPVFVGRT Mvan_5652|M.vanbaalenii_PYR-1 DDGSWGPWYEAEPLEG------------VGADLPGP---RGTEPVFVGRT MSMEG_6406|M.smegmatis_MC2_155 ADGSWGPWYEAEALDG------------VGADTPGP---RGTDPVFVGRT TH_0898|M.thermoresistible__bu -------------------------------------------------- MAB_0168c|M.abscessus_ATCC_199 TDGSWGQWYELDPVESGDP---------AAEHKGIP---AATEPVFVGST MLBr_01002|M.leprae_Br4923 LGGPVNSDLGFPIIDEVPG--------LAGPDSRVSIFAASDNPVIFWTP MMAR_5375|M.marinum_M NTVEIAVTRPIDAPVTQPPPTGEP-EPVD--LGYRPATKELPFGQNISAV MUL_4995|M.ulcerans_Agy99 NTVEIAVTRSIDAPVTQPPPTGEP-EPLD--LGYRPATKELPFGQNISAV Mb3841|M.bovis_AF2122/97 TTVQVAVTRPIDAPITQPPAGRPPNDLLDSGLGYRPATKEQPFGQNISAI Rv3811|M.tuberculosis_H37Rv TTVQVAVTRPIDAPITQPPAGRPPNDLLDSGLGYRPATKEQPFGQNISAI MAV_0206|M.avium_104 TTVQIAVTRPLDAPATQPPP-----RPADD-LGYRPASREQPFGQNISAV Mflv_1157|M.gilvum_PYR-GCK TTVQIAVTRPDDAPATRPAAPAAPAPTGPA-LGYVPANVEQPLAENVTAV Mvan_5652|M.vanbaalenii_PYR-1 TTVQVAVTRPSDAPPIGPAA-AAHKPDGPA-LGYIPANVESPLPQNITAV MSMEG_6406|M.smegmatis_MC2_155 NTVQIAITRPENAAPTAPAPKNKDDKNKPD-LGYRPATVQQPLGQNVTAV TH_0898|M.thermoresistible__bu -------------------------------------------------- MAB_0168c|M.abscessus_ATCC_199 HSAQVAVQPKYGANVKSPKTDNRR-TPADAGLGYRPASIEQPLTTGLDAI MLBr_01002|M.leprae_Br4923 DHGAFVVRGALNAAWDKLGSSAGVLGVPVADESFDGEVISQKFSGGAVFW MMAR_5375|M.marinum_M LISPPQAPAGTHWTPP-----TGVTMPGQAPPIISRADWGADEALRCESP MUL_4995|M.ulcerans_Agy99 LISPPQAPAGTHWTPP-----TGVTMPGQAPPIISRADWGADEALRCESP Mb3841|M.bovis_AF2122/97 LISPPQAPPGTQWTPP-----TAVTMAGQPPAIISRAEWGADESLRCETP Rv3811|M.tuberculosis_H37Rv LISPPQAPPGTQWTPP-----TAVTMAGQPPAIISRAEWGADESLRCETP MAV_0206|M.avium_104 LISPPQAPSETHWTPP-----SGVVMPGQAPPIISRAEWGADESLRCGSP Mflv_1157|M.gilvum_PYR-GCK LISPPEAPPDLGPLP------NAATPAGQPPRIINRVEWGADEGMRCGEP Mvan_5652|M.vanbaalenii_PYR-1 LISPPQAPPDLVPLP------NAATPAGQPPRIINRVEWGADEGMRCGEP MSMEG_6406|M.smegmatis_MC2_155 LISPPQAPADIGPLP------TAVTAPGVPPHIIGRAQWGADESMRCP-A TH_0898|M.thermoresistible__bu -------------------------------------------------- MAB_0168c|M.abscessus_ATCC_199 LISPKLAPPDAARFEERWS--APVALPQAGPRIITRAQWGANESDRCP-P MLBr_01002|M.leprae_Br4923 NKKSSEFTTEPTALAEQLTGLLVATDPTTAISMAWRAAGGVSGPLGPKQG MMAR_5375|M.marinum_M EYDRAVRAAVVHHTAGSNDYSPLES-AGIVKAIYTYHSKTLG---WCDIA MUL_4995|M.ulcerans_Agy99 EYDRTVRAAVVHQTAGSNDYSPLES-AGIVKAIYTYHSKTLG---WCDIA Mb3841|M.bovis_AF2122/97 EYDRGVRAAVVHHTAGSNDYSPLES-AGIVKAIYTYHSKTLG---WCDIA Rv3811|M.tuberculosis_H37Rv EYDRGVRAAVVHHTAGSNDYSPLES-AGIVKAIYTYHSKTLG---WCDIA MAV_0206|M.avium_104 QYDNGIRAAVVHHTAGNNDYSPLES-AGIVKAIYTYHSKTLG---WCDIA Mflv_1157|M.gilvum_PYR-GCK RYDNKIRAGVLHHTAGSNEYGPGDS-AGIIRSIYEYHTRTLG---WCDIA Mvan_5652|M.vanbaalenii_PYR-1 RYDTRIRAGVVHHTAGSNEYTPEDS-AGIVRSIYEYHTRTLG---WCDIA MSMEG_6406|M.smegmatis_MC2_155 VYDAGIRAGIVHHTAGSNDYAPEDS-AGIVRSIYEYHTRTLG---WCDIA TH_0898|M.thermoresistible__bu -------------------------------------------------- MAB_0168c|M.abscessus_ATCC_199 VYNRDVRAGVVHHTAGSNNYSPYDS-AAIIRAIYAYHTKTLK---WCDIA MLBr_01002|M.leprae_Br4923 GQHPIGADGIIQDFAGGKVFFSKATGANAVENDILAKYESLGGPVGSDLG MMAR_5375|M.marinum_M YNALVDKYG--------------------------------------QIF MUL_4995|M.ulcerans_Agy99 YNALVDKYG--------------------------------------QIF Mb3841|M.bovis_AF2122/97 YNALVDKYG--------------------------------------QVF Rv3811|M.tuberculosis_H37Rv YNALVDKYG--------------------------------------QVF MAV_0206|M.avium_104 YNALVDKYG--------------------------------------QVF Mflv_1157|M.gilvum_PYR-GCK YNAMVDKYG--------------------------------------QVF Mvan_5652|M.vanbaalenii_PYR-1 YNAMVDKYG--------------------------------------QVF MSMEG_6406|M.smegmatis_MC2_155 YNALVDKYG--------------------------------------QVF TH_0898|M.thermoresistible__bu -------------------------------------------------- MAB_0168c|M.abscessus_ATCC_199 YNVLVDKYG--------------------------------------QIF MLBr_01002|M.leprae_Br4923 FPAANEGDGGIVTSSRIAIFSAADKPVIFWTPDHGAFVVRGAMKAAWDKL MMAR_5375|M.marinum_M EGSAGGLTKPVEGFHTGG--FNRDTWGVAMIGNFDDVAPTPLQIRAVGRL MUL_4995|M.ulcerans_Agy99 EGSAGGLTKPVEGFHTGG--FNRDAWGVAMIGNFDDVAPTPLQIRAVGRL Mb3841|M.bovis_AF2122/97 EGSAGGLTKPVEGFHTGG--FNRNTWGVAMIGNFDDVAPTPIQIRTVGRL Rv3811|M.tuberculosis_H37Rv EGSAGGLTKPVEGFHTGG--FNRNTWGVAMIGNFDDVAPTPIQIRTVGRL MAV_0206|M.avium_104 EGSAGGLTKAVEAFHTGG--FNRNTWGVAMIGNFDDVPPTPVQLRAVGRL Mflv_1157|M.gilvum_PYR-GCK EGRAGGMTRPVEGAHTGG--FNHNTWGVAMLGNFEAVPPTPIQLRNTSRL Mvan_5652|M.vanbaalenii_PYR-1 EGRAGGMNRPVEGAHTGG--FNHNTWGVAMLGNFDVVPPTPIQLRNTATL MSMEG_6406|M.smegmatis_MC2_155 EGRAGGMDRPVEGAHTGG--FNRDTWGVAMMGNFDAVPPTPIQLRTTGRL TH_0898|M.thermoresistible__bu -------------------------------------------------- MAB_0168c|M.abscessus_ATCC_199 EGRFGGITNNVQGAHTGG--FNEHSWGIALIGDFTRDEPSPAMLQAAGRI MLBr_01002|M.leprae_Br4923 KGPNGKLGVPVADQSVDGNVISQRFIGGKISWNRANNTFTADPANLASLL MMAR_5375|M.marinum_M LGWRLGIAEVDPKSMVELESTGSS-------------------------- MUL_4995|M.ulcerans_Agy99 LGWRLGIAEVDPKSMVELESTGSS-------------------------- Mb3841|M.bovis_AF2122/97 LGWRLGMDDVDPRSMVDLQSAGSS-------------------------- Rv3811|M.tuberculosis_H37Rv LGWRLGMDDVDPRSMVDLQSAGSS-------------------------- MAV_0206|M.avium_104 LGWRLGMDGVDPKGTVQLESAGSH-------------------------- Mflv_1157|M.gilvum_PYR-GCK LGWVLGQSGVDPLGSVVLPSEGGS-------------------------- Mvan_5652|M.vanbaalenii_PYR-1 LGWVLGQAGVDPLATVVMPSEGGS-------------------------- MSMEG_6406|M.smegmatis_MC2_155 LGWRLGLDRIDPHGTVVLASEGGS-------------------------- TH_0898|M.thermoresistible__bu -------------------------------------------------- MAB_0168c|M.abscessus_ATCC_199 LGWRLRLAGVDPRGQVDLASEGGP-------------------------- MLBr_01002|M.leprae_Br4923 SGLQVSEQSQPSELAMLFHAKKSTGHWWWLVAAVAVLLVIVMFVLLALGW MMAR_5375|M.marinum_M --------YTTVPGGAIAKLPAIFTHRDVGNTDCPGNAAYALMDEIREIA MUL_4995|M.ulcerans_Agy99 --------YTTVPGGAIAKLPAIFTHRDVGNTDCPGNAAYALMDEIREIA Mb3841|M.bovis_AF2122/97 --------YTTFPGGAIARLPAIFTHRDVGNTDCPGNAAYAVMDEIRDIA Rv3811|M.tuberculosis_H37Rv --------YTTFPGGAIARLPAIFTHRDVGNTDCPGNAAYAVMDEIRDIA MAV_0206|M.avium_104 --------YTTYAAGTVATLPTIFTHRDVGNTDCPGNAAYALMDEIRDIA Mflv_1157|M.gilvum_PYR-GCK --------FTKFPFGAPTTLPAIFTHRDVGNTECPGAAAYALLPEVRNIA Mvan_5652|M.vanbaalenii_PYR-1 --------FTKFPFGASPTLPTIFTHRDVGNTECPGNAAYALMGQIRDIA MSMEG_6406|M.smegmatis_MC2_155 --------FTHFPRGATPTLPAIFTHRDVGNTDCPGNAAYAEMGRLRDIA TH_0898|M.thermoresistible__bu ------------------------------------------MDRIRQIA MAB_0168c|M.abscessus_ATCC_199 --------FTTVPGGKVVTLPTIFTHRDVGNTECPGEAAYRLIPRLRDIA MLBr_01002|M.leprae_Br4923 RRRRTAHDIVADSHDHDMDVGMDFGYKAAVDGQCTYDAESGTEHPVRDVE :*:: MMAR_5375|M.marinum_M SHFN-----DPP--EELLKSLEGGAIY------QRWQELGAMNSVLGAPT MUL_4995|M.ulcerans_Agy99 SHFN-----DPP--EELLKSLEGGATY------QRWQELGAMNSVLGAPT Mb3841|M.bovis_AF2122/97 AHFN-----DPP--EELIKALEGGAIY------QRWQALGGMNSALGAPT Rv3811|M.tuberculosis_H37Rv AHFN-----DPP--EELIKALEGGAIY------QRWQALGGMNSALGAPT MAV_0206|M.avium_104 AHVN-----DPP--EELIKALQGGAIY------AHWQEIGGMNSVLGAPT Mflv_1157|M.gilvum_PYR-GCK ARFN-----DPPGPEQLAETLRGGAIH------AKWESLGGMNSYLGRPT Mvan_5652|M.vanbaalenii_PYR-1 ARFN-----DPPGPEQLAETLRGGAIH------AKWEALGGMNSYLGRPT MSMEG_6406|M.smegmatis_MC2_155 ARFN-----QPPGPEELAEQMRGGAIF------ARWESVGGPAGPLGNPT TH_0898|M.thermoresistible__bu ARFK-----EPPGPEDLADTLRGGAIH------ARWEAMGGMASVLGGPT MAB_0168c|M.abscessus_ATCC_199 AGAAN---GEPP---DLVDSLRGGAIY------DTWTRLGSAESDLGAPT MLBr_01002|M.leprae_Br4923 RGPTVSWLRGAQDATGLAQDARLGPAFGSELPSESEEPLGLEEDDPDAVD . * . . *. . :* . . MMAR_5375|M.marinum_M SPEADGADGARYATFAKG-AMYWSPTTGAQPVTG---------AIYDAWA MUL_4995|M.ulcerans_Agy99 SPEADGAGGARYATFAKG-VMYWSSTTGAQPVTG---------AIYDAWA Mb3841|M.bovis_AF2122/97 SPEADAADGARYATFAKG-AMYWSPVTDAQPITG---------AIYEAWA Rv3811|M.tuberculosis_H37Rv SPEADAADGARYATFAKG-AMYWSPVTDAQPITG---------AIYEAWA MAV_0206|M.avium_104 APEDSAADDARFVTFVRG-AMYWSPQTGAQPVTG---------AIYDAWG Mflv_1157|M.gilvum_PYR-GCK SPEASGLGATRYVTFEHG-AVYWSPETGAEPVTG---------ELYKAWG Mvan_5652|M.vanbaalenii_PYR-1 SPEASGEGATRYVTFEHG-AVYWSPESGAEPVTG---------ELYNAWG MSMEG_6406|M.smegmatis_MC2_155 SPEAAAEGEARYATFERG-AIYWSPVTGAQPLTG---------AIYEAWG TH_0898|M.thermoresistible__bu SPETIGANGSRYVTFEKG-AIYWSPETGAQPLTG---------AIYAVWG MAB_0168c|M.abscessus_ATCC_199 SVEQQAVGEARFATFRNG-AMYFSPGTGAHPVVG---------AIYHAWA MLBr_01002|M.leprae_Br4923 TDSMPALSDADFPYAALSDAAHWDADAAEVVATDNSSVATDNSSLLETAA : . . . : : . . ::.. : .. : . . MMAR_5375|M.marinum_M SLSYERGPLGLPTSAEIQEPLRITQNFQHGVLNFQRLTGNVSEVVNGITT MUL_4995|M.ulcerans_Agy99 SLSYERGPLGLPTSAEIQEPLRITQNFQHGVLNFQRLTGNVSEVVNGITT Mb3841|M.bovis_AF2122/97 SQSYERGPLGLPTSAEIQEPLQITQNFQHGTLNFERLTGNVTEVVDGITT Rv3811|M.tuberculosis_H37Rv SQSYERGPLGLPTSAEIQEPLQITQNFQHGTLNFERLTGNVTEVVDGITT MAV_0206|M.avium_104 SQSYERGPLGLPTSAEIQEPLQITQNFQHGTLNYERLTGNVTEVLDGITT Mflv_1157|M.gilvum_PYR-GCK ALGFERGALGLPTSAEIAEPLWIVQNFQHGTLNFDREKGTVTRVTDGVPV Mvan_5652|M.vanbaalenii_PYR-1 SLGFERGALGLPTSAEIPEPLWIVQNFQHGTLNFDRETGAVTRVIDGVPV MSMEG_6406|M.smegmatis_MC2_155 RLGFERGALGLPTSGEIHEPLWIKQNFQHGTLNFDREKHTVVRVIDGVPQ TH_0898|M.thermoresistible__bu SLGFERGLLGLPTSAEIHEPQWIVQNFQHGTLNFDRENGRVVRVVDGVEL MAB_0168c|M.abscessus_ATCC_199 ETDFERGPLGLPVTDEIGEPNIIVQNFQNGSLIYDRASGRVSSVINGETR MLBr_01002|M.leprae_Br4923 DTEVSTGRHAAVDMADAMDASFPGVTVPRMLFRPSPTLRPTIHLPLDDPY . * . : :. .. . : . . : . MMAR_5375|M.marinum_M PLATKPPSGPMVPPEHFSLPIHPIIP----------------------- MUL_4995|M.ulcerans_Agy99 PLATKPPSGPMVPPEHFSLPIHPIIP----------------------- Mb3841|M.bovis_AF2122/97 PLATRPPSGPTVPPEHFTLPTHPIT------------------------ Rv3811|M.tuberculosis_H37Rv PLATRPPSGPTVPPEHFTLPTHPIT------------------------ MAV_0206|M.avium_104 PLATQLPSGPTVPAEHFSLPTHPAAT----------------------- Mflv_1157|M.gilvum_PYR-GCK ELPP--ADLNPVQLERFTPPSNPV------------------------- Mvan_5652|M.vanbaalenii_PYR-1 ELPPPGADSTPVQLERFTPPSNPA------------------------- MSMEG_6406|M.smegmatis_MC2_155 ELPPAAPDDQPVQLERFTPIA---------------------------- TH_0898|M.thermoresistible__bu EIPLPEPDAYPVQLERFTPAINP-------------------------- MAB_0168c|M.abscessus_ATCC_199 EILGVAPVAQNALPEQFSAPAAPAAPPPPAPAPPPPPPPVEQFAPAN-- MLBr_01002|M.leprae_Br4923 QVPDGYPIKASPRFGLYYTPASELYHDTLAEVWLANEEIAQVNGFIKAD : . :