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NSLGMSIGATQLVATDGNPDGVPVVRSSLLTLHEDQPSEVGVPKEPGLGLAGFVDRVGDPVGIVGADGSV HSADWVMAEAIRIMIADAAVVANFDSPPALAAAVPAYWGGHSIAALRAAIDKVPALAPGGRPMKLVPDAR AALVSMRDRIPHHGVVVVCDFGGTGTSITLADAADDFATLGESVRFRDFSGQRIDQELLALVLANLNQDP DGTASLGALTRLRDRCRAAKEHLSTDTTTVIPVALPGLASDVRLTRGELEERIREPLSALITKIQETLEY NNIAPASVAAVLTVGGGSSIPLVTQQLSERLRCPIIAAPHPQLAVAFGAAFMAGQPDETPSAEATMRSPE ATMLRPVATGEETAKSPASAPIDTVESGLAWSESDTSPELQEYEDYQDYSTPTTTARPEVTFSPAPDDYR DTPPMRWFQRPVLWFFAAAVFSAAVFTALFIAWQDRDEAPAPSNRTSTTTTATSTPHP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2498c | - | - | 100% (479) | hypothetical protein MAB_2498c |
| M. abscessus ATCC 19977 | MAB_4291 | - | e-149 | 55.51% (499) | hypothetical protein MAB_4291 |
| M. abscessus ATCC 19977 | MAB_4273c | dnaK | 8e-08 | 23.32% (283) | molecular chaperone DnaK |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2287c | - | 2e-82 | 38.25% (502) | hypothetical protein Mb2287c |
| M. gilvum PYR-GCK | Mflv_0276 | - | 1e-92 | 41.60% (500) | hypothetical protein Mflv_0276 |
| M. tuberculosis H37Rv | Rv2264c | - | 2e-82 | 38.25% (502) | hypothetical protein Rv2264c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3358 | - | 3e-88 | 39.52% (496) | hypothetical protein MMAR_3358 |
| M. avium 104 | MAV_2177 | - | 1e-76 | 38.10% (496) | hypothetical protein MAV_2177 |
| M. smegmatis MC2 155 | MSMEG_0692 | - | 9e-97 | 43.76% (489) | hypothetical protein MSMEG_0692 |
| M. thermoresistible (build 8) | TH_4466 | - | 1e-82 | 44.09% (406) | PUTATIVE conserved hypothetical proline and threonine rich |
| M. ulcerans Agy99 | MUL_0582 | - | 3e-65 | 35.14% (518) | hypothetical protein MUL_0582 |
| M. vanbaalenii PYR-1 | Mvan_0621 | - | 1e-95 | 44.27% (506) | hypothetical protein Mvan_0621 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0276|M.gilvum_PYR-GCK ----MTEPLGLSIGTTNLVAAR--VGRPPVTRRAILTLVAGQAPQVGTPE
Mvan_0621|M.vanbaalenii_PYR-1 ----MTEPLGLSIGMTNLVAAR--VGRPPVTRRSILNLYTDRAPEVGAPS
MSMEG_0692|M.smegmatis_MC2_155 ----MTDSLGLSIGITNLVAAR--EGRAPVVRRSILNLYRDRAPEVG---
TH_4466|M.thermoresistible__bu ----MTDPLGLSVGMTNLVAAR--IGQPPVLRRAVLTMFGDRPPEVGVPD
MUL_0582|M.ulcerans_Agy99 -MWDMSESLGLSIGVANLVATR--AGGAPLRRASVLHLFQHQAAEVGLPE
MAB_2498c|M.abscessus_ATCC_199 -----MNSLGMSIGATQLVATDGNPDGVPVVRSSLLTLHEDQPSEVGVPK
Mb2287c|M.bovis_AF2122/97 MATGARPALGLSIGVTNLAAVA---ADHSITRKPVLTLYRQRPPEVGVPS
Rv2264c|M.tuberculosis_H37Rv MATGARPALGLSIGVTNLAAVA---ADHSITRKPVLTLYRQRPPEVGVPS
MMAR_3358|M.marinum_M MAEGARPALGLSIGATNLAAVT---ADSAILRKPVLTLYRQRPPEIGLPS
MAV_2177|M.avium_104 MANGAGTALGLSIGATNLAAVT---SDHAVTRKPVLTRYPDRPAEVGVPA
.**:*:* ::*.*. .: * .:* :..::*
Mflv_0276|M.gilvum_PYR-GCK ENAGNNP-------SGVVLTGFVDRVGDPVPLIAEDGSAHRGEQVLAAAL
Mvan_0621|M.vanbaalenii_PYR-1 EIPGFSQ-------PRLVLSGFVERVGDPVPLVAADGSAHRGEQTLAQAL
MSMEG_0692|M.smegmatis_MC2_155 ELGG----------DGLALTGFVERTGDPVPIVAADGSQHRGELALAEAL
TH_4466|M.thermoresistible__bu PGAGSVDGPAPGLGGGMVLSGFVERIGDPVPLVAADGTAHRGERVLVEAL
MUL_0582|M.ulcerans_Agy99 ENPGLAG-------AGLVLRGFVERVGDQSPLIAADGTKYLGEALAVQAL
MAB_2498c|M.abscessus_ATCC_199 E-------------PGLGLAGFVDRVGDPVGIVGADGSVHSADWVMAEAI
Mb2287c|M.bovis_AF2122/97 ENPRLDE-------PGLVITDFVDRVGDSVGIVAADGSVYRSEALVADAL
Rv2264c|M.tuberculosis_H37Rv ENPRLDE-------PGLVITDFVDRVGDSVGIVAADGSVYRSEALVADAL
MMAR_3358|M.marinum_M ENPRLDQ-------SGLVISDFVDRVGDQIGIVAADGSVHRSEALVADAL
MAV_2177|M.avium_104 ENPRLQG-------PGVVITGFVNRVGDPRPVVASDGSVHRSEILLADAL
: : .**:* ** ::. **: : .: . *:
Mflv_0276|M.gilvum_PYR-GCK DAMAR----LVDGGSP--VAIAVPSHWGPGTVGALRGALRTVPSLSP---
Mvan_0621|M.vanbaalenii_PYR-1 DAMAG----LVDGGAP--VAIAVPAHWGPGTVGALRGALRAAPRLSP---
MSMEG_0692|M.smegmatis_MC2_155 DAMAR----EVGGGAP--VAIATPAYWGPAALGALRGALRNKPAFAP---
TH_4466|M.thermoresistible__bu DAMAR----QVGYGAP--IAVAIPAHWGPGTVGALRGALRDKPSLCP---
MUL_0582|M.ulcerans_Agy99 SALAR----TVGYGSP--VTIAAPAYWSGAQLGALRGALLTEPALAP---
MAB_2498c|M.abscessus_ATCC_199 RIMIADAAVVANFDSPPALAAAVPAYWGGHSIAALRAAIDKVPALAP---
Mb2287c|M.bovis_AF2122/97 LALAYT--ATGGRALPGSVTVTYPAHWGPAAVAALDSALRRASEWSHGTS
Rv2264c|M.tuberculosis_H37Rv LALAYT--ATGGRALPGSVTVTYPAHWGPAAVAALDSALRRASEWSHGTS
MMAR_3358|M.marinum_M RALAYT--ATGGHTLPASTAVAYPAHWTTSAVDALGAALGRVPEWSP---
MAV_2177|M.avium_104 RALAYA--ATGGRALPDDIAVTYPAHWESAAVEALGAALGEIPEWSR---
: . * : : *::* : ** .*: . .
Mflv_0276|M.gilvum_PYR-GCK -GGVPATLIPDSTAALASLRVSPGLPGSGVVVLVDLGGSGSSVTLADAGA
Mvan_0621|M.vanbaalenii_PYR-1 -NGIPPALIPDATAALAALRVTPGLPSQGVVVLVDLGGSGSSITLADAGS
MSMEG_0692|M.smegmatis_MC2_155 -DGIPAALVPDSMAALAALKADPGLPADGVVVLCDFGGSGTSVTLADAAA
TH_4466|M.thermoresistible__bu -DGLPPALVPDSVAALAALQAAPGLPAEGVIVLCDFGGTGTSISLANAGS
MUL_0582|M.ulcerans_Agy99 -NGVAAAVVSDAAAALAALRPTPGFPASGVVALCDFGAGGTSVTLAQVGS
MAB_2498c|M.abscessus_ATCC_199 -GGRPMKLVPDARAALVSMRDR--IPHHGVVVVCDFGGTGTSITLADAAD
Mb2287c|M.bovis_AF2122/97 STAQPLSLLPDAAAALYAIRADPGIPARGIVAVCDFGGSGTGITLVDAAD
Rv2264c|M.tuberculosis_H37Rv STAQPLSLLPDAAAALYAIRADPGIPARGIVAVCDFGGSGTGITLVDAAD
MMAR_3358|M.marinum_M -AGQPLLLIPDAAAALFAARANPGIPARGVVAVCDFGGSGTSITLADASG
MAV_2177|M.avium_104 -RARPIVLIPDAAAALLAVRTSPGLPARGTVAVCDFGGSGTSITLMDADG
. . ::.*: *** : : :* * :.: *:*. *:.::* :.
Mflv_0276|M.gilvum_PYR-GCK NLVVVGQTVRYPEFSGDGIDRALLDHVLAGVSDTGQAD---TAGTAAVGP
Mvan_0621|M.vanbaalenii_PYR-1 GAATIGQTVRYPDFSGEAIDQALLGHVLTGIADADTADPAGTAGTAAVGP
MSMEG_0692|M.smegmatis_MC2_155 DYATLGQTVRYPEFSGDQIDQALLNHVLTGIAAANDAD---PAGTAAVGS
TH_4466|M.thermoresistible__bu NLDAIGDTVRHTEFSGDLIDQLLLDHVLAGAAADAEAD---PAATAAVGA
MUL_0582|M.ulcerans_Agy99 SLQQIGPTFRYREFSGDEIDQLILNHILTVTPGIDSAEV--SGTATSMGS
MAB_2498c|M.abscessus_ATCC_199 DFATLGESVRFRDFSGQRIDQELLALVLANLNQD-------PDGTASLGA
Mb2287c|M.bovis_AF2122/97 EYRPVAATVRHQAFSGDLIDQSLLSYVMSELPGTGAFD---PAGTSAIGS
Rv2264c|M.tuberculosis_H37Rv EYRPVAATVRHQAFSGDLIDQSLLSYVMSELPGTGAFD---PAGTSAIGS
MMAR_3358|M.marinum_M EYQPLGATVRHPDFSGDLIDQSLLTYVMSEMPATGSFD---PSGTSAIGS
MAV_2177|M.avium_104 DYRALAPTLRHRDFSGDVIDQALLGVVVANMPTTGAF----PTGTAAIGS
:. :.*. ***: **: :* ::: . ::::*.
Mflv_0276|M.gilvum_PYR-GCK LMRLREECRAAKERLSSETATAVPVDLPGFR-SEVRVTRPELEQMIAGPL
Mvan_0621|M.vanbaalenii_PYR-1 LSRLRDECRAAKERLSGETATAVPVELPGFS-SDVRVTRPELEQLISEPL
MSMEG_0692|M.smegmatis_MC2_155 LAHLRSDCRNAKEALSADTVATISADLPGYT-SEVRVTRPELEQLISAPL
TH_4466|M.thermoresistible__bu LARLREDCRRAKERLSADTVAVVPVALPAFQ-SDVRVTRPELEQLIAGPL
MUL_0582|M.ulcerans_Agy99 VTLLLGGCRFAKEHLSAAPVATIATGAAGQPGADIRFSRNEFEQLITQPL
MAB_2498c|M.abscessus_ATCC_199 LTRLRDRCRAAKEHLSTDTTTVIPVALPGLA-SDVRLTRGELEERIREPL
Mb2287c|M.bovis_AF2122/97 LTKLRIECRKAKERLSSSTVTTLTDALG----GDIRLTRNELEDTIRDSL
Rv2264c|M.tuberculosis_H37Rv LTKLRIECRKAKERLSSSTVTTLTDALG----GDIRLTRNELEDTIRDSL
MMAR_3358|M.marinum_M LNRLRAECRQAKEQLSLSTVATLSDALPGVS-GEVRLTRNELDETIRDSL
MAV_2177|M.avium_104 LSRLRGGCRVAKEQLSANTTTTLTDGLTGVR-GEIRLTRAELDDAIAPAL
: * ** *** ** ..:.:. .::*.:* *::: * .*
Mflv_0276|M.gilvum_PYR-GCK DGLLSLIDDTLTRNGVATENISAIATVGGGAAIPLVTQRLSERLRAPVVT
Mvan_0621|M.vanbaalenii_PYR-1 TGLLSAIDDVLQRNGIAAGDVSAVATVGGGAAIPLVTQRLSERLRAPVVT
MSMEG_0692|M.smegmatis_MC2_155 DGFLNAVEDTLQRNNIALSSVTAVATVGGGAAIPYVTQRLSERLRAPVVT
TH_4466|M.thermoresistible__bu AGVLNAIDDTLQRNQIAPQRVTAVATVGGGAAIPLITQRLSERWRAPVIT
MUL_0582|M.ulcerans_Agy99 DRFIGSVEDMLQRSGVPRPSLAAVAAVGGGAAIPLIGNRLSERLQVPVFT
MAB_2498c|M.abscessus_ATCC_199 SALITKIQETLEYNNIAPASVAAVLTVGGGSSIPLVTQQLSERLRCPIIA
Mb2287c|M.bovis_AF2122/97 DSVGRALEQTLARSGIRTAELVAIVSVGGGANIPAVTTTLSGRFCVPVVR
Rv2264c|M.tuberculosis_H37Rv DSVGRALEQTLARSGIRTAELVAIVSVGGGANIPAVTTTLSGRFCVPVVR
MMAR_3358|M.marinum_M DGFARVVEHTLQRAGVPAADLVAIVTVGGGANIPSVTTTLSGRFGVPVIT
MAV_2177|M.avium_104 GGFVTVLRETLSRNGIR--DLAAVVSTGGGANLPAVTTTLARHFRVPVAT
. : . * : : *: :.***: :* : *: : *:
Mflv_0276|M.gilvum_PYR-GCK TPQALLNIGAGAALIANQTLDADAPTGMAPTG------MAAAADVPTAMG
Mvan_0621|M.vanbaalenii_PYR-1 TPEPALNVAAGAALVANQSLATDAPTGMAP-----------AADAPTAMG
MSMEG_0692|M.smegmatis_MC2_155 SPQPQLVAAAGAALLADRAVDAGAPTGLAPG--------VAAADAPTGLG
TH_4466|M.thermoresistible__bu TPQPQFNVAAGAALISARGXXX----------------------------
MUL_0582|M.ulcerans_Agy99 TAQPIFSAAIGAAMLGQDQSSAGAPTGAGPAVDMPTNIVGAAGTIGAMTE
MAB_2498c|M.abscessus_ATCC_199 APHPQLAVAFGAAFMAGQPDETPSAEATMRS-------------------
Mb2287c|M.bovis_AF2122/97 TPRPQLTAAFGGALWAARRPGDTSATVLTAVTSAT------------ATA
Rv2264c|M.tuberculosis_H37Rv TPRPQLTAAFGGALWAARRPGDTSATVLTAVTSAT------------ATA
MMAR_3358|M.marinum_M APRPQLTAATGGALRAARGPGDSSATVLTSAAPMTQTAMAPLDPDVGAVA
MAV_2177|M.avium_104 TPHPQLTAAVGAALRVAH--ADAGATFTAPAAPAT------------ATA
:... : . *.*:
Mflv_0276|M.gilvum_PYR-GCK --PAVDAPTALGPAAPPVAGG--------ALAWSQDDDGVQDPLPYTGAD
Mvan_0621|M.vanbaalenii_PYR-1 --HAAWAAGAAGLAATESAGDGASSATFRALAWSQDDDAAGDPLPYTGED
MSMEG_0692|M.smegmatis_MC2_155 PTAALGAAGAAGTDGPESSTFR-------ALAWSEDDAPAGEPVPYAGPD
TH_4466|M.thermoresistible__bu --------------------------------------------------
MUL_0582|M.ulcerans_Agy99 VSPTAWANQAGSAAASESASDNAKSATYRALAWSQDADTGNEPVPYTGPD
MAB_2498c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 PADAPASVLQPALAWSEADEDSHIGP--------APGYTAARPSLSFDHD
Rv2264c|M.tuberculosis_H37Rv PADAPASVLQPALAWSEADEDSHIGP--------APGYTAARPSLSFDHD
MMAR_3358|M.marinum_M AADAPVSALQPALAWSEADDQSRAMPVVGDDYSGASGYTSARPQLTFEEN
MAV_2177|M.avium_104 RAAARPEPREDVTATAAVPPAN-------------PAPMEAQAWSDTGTD
Mflv_0276|M.gilvum_PYR-GCK YTSPAGYGDAATGARPPVAFAPGDDGYSDDLPPLPWYKRPPVLFGLAAA-
Mvan_0621|M.vanbaalenii_PYR-1 YTVAGGYADPGTAARPSVDFAGQDDTYTDELAPLPWYKRPPVLFGVAAA-
MSMEG_0692|M.smegmatis_MC2_155 YETQAG----ATAARPPVEFSHEEEMYDAGPAPLPWYKRPPILFGAAAV-
TH_4466|M.thermoresistible__bu --------------------------------------------------
MUL_0582|M.ulcerans_Agy99 ATGEYG---REPATDYAPRYDYPDQDRYAEAAPLPWYKRAAVVFSLAAAG
MAB_2498c|M.abscessus_ATCC_199 -------------------------------------PEATMLRPVATG-
Mb2287c|M.bovis_AF2122/97 AHAEPE----------------------PKSPPIPWYR-LPAVIITGTTV
Rv2264c|M.tuberculosis_H37Rv AHAEPE----------------------PKSPPIPWYR-LPAVIITGTTV
MMAR_3358|M.marinum_M ARAEPA----------------------PKSVVIPWYR-LPGVIIVATVV
MAV_2177|M.avium_104 AAVPPP----------------------RRKRLFTRSRLFPTAAVVIAAA
Mflv_0276|M.gilvum_PYR-GCK AALLAVGGLAVTLTSSEG-STTVTETASTTAPSDTTPVELPPPVTTVTIG
Mvan_0621|M.vanbaalenii_PYR-1 AALLAAGGLAVTLTGSQGDSGTVTETAS--VPTETPPAELPPPVTTVTVG
MSMEG_0692|M.smegmatis_MC2_155 AALLAAGGLAVTLTSTSGDSTPVTETSTTYSMGPSPEGPPPEPVTTVTVG
TH_4466|M.thermoresistible__bu --------------------------------------RLSRPASTPRSG
MUL_0582|M.ulcerans_Agy99 LAILVAVVLGLTLGTSNN-----------KPVNTTVPAPSPEPITTTILG
MAB_2498c|M.abscessus_ATCC_199 --------------------------------EETAKSPASAPIDTVESG
Mb2287c|M.bovis_AF2122/97 AVLLVGAAVAIGLSTG---------------DQPTAPGTPQRPGVTTTAA
Rv2264c|M.tuberculosis_H37Rv AVLLVGAAVAIGLSTG---------------DQPTAPGTPQRPGVTTTAA
MMAR_3358|M.marinum_M AVLLVGAAVAIALSSG---------------EQP-ATRSPEATTSPPTSA
MAV_2177|M.avium_104 ALLLVGTALMIGLTAQ---------------NKSDKSVTTPAPTLSTTPA
. . .
Mflv_0276|M.gilvum_PYR-GCK PDGVA----TTTVSQPPPPPPSSTSSTTTTTPSSSTTTTTTTTTTTTTTT
Mvan_0621|M.vanbaalenii_PYR-1 ADGIA----TTTVSQPPPPPPSSSTTTPTTASTTSPTTTTTTTTTTTTTT
MSMEG_0692|M.smegmatis_MC2_155 PDGQQ----TTTVVVPPPVTTTTTEPTSTTSPTTTTTTTTTTTTTTTTTT
TH_4466|M.thermoresistible__bu SEIRA----SRSAR---------VTRTTDRWPGSSTATSATVSADNRSLA
MUL_0582|M.ulcerans_Agy99 PNSSP----TVTVITPTPPSTTTTSPSATTTTTQPTTTTTTTTTTTTTPP
MAB_2498c|M.abscessus_ATCC_199 LAWSE----SDTSPELQEYEDYQDYSTPTTTARPEVTFSPAPDDYRDTPP
Mb2287c|M.bovis_AF2122/97 PPPSPAPASDGPTTEPAPPVQAPATGGPAPPLQQPLPPPPTTTNTQPAVT
Rv2264c|M.tuberculosis_H37Rv PPPSPAPASDGPTTEPAPPVQAPATGGPAPPLQQPLPPPPTTTNTQPAVT
MMAR_3358|M.marinum_M PAAVP-PVTDAGTSAPAPSTQPPASQEPAPPPTQQAPPPPSTEAPPPSTT
MAV_2177|M.avium_104 PPPPS------------------VTAEPAPPPAD-IPVPSTSDTNPPAET
. . ..: : .
Mflv_0276|M.gilvum_PYR-GCK TNTAPTTTTTRTTTAPPTTTPPPTTTQAPPPPT------------TEEPP
Mvan_0621|M.vanbaalenii_PYR-1 T-----TTTTRTTTTQPTTTAPPTTTQPPPPTT------------TAAPP
MSMEG_0692|M.smegmatis_MC2_155 TPTTTRTTTTQPTTTAPTTTAPPTTTQAPITTT------------TVEIP
TH_4466|M.thermoresistible__bu RRQCSRSLLNAPTAAVPAGSVPPDWATLSSTND------------SRA--
MUL_0582|M.ulcerans_Agy99 TTTTTQPTTTRTTTTQPTTTAPPTTTQQPSTTT------------AAPIT
MAB_2498c|M.abscessus_ATCC_199 MRWFQRPVLWFFAAAVFSAAVFTALFIAWQDRD------------EAPAP
Mb2287c|M.bovis_AF2122/97 TDVITPAP-TTPASAPPATTQPPATTQPPATTS-------PSPPPIPPIP
Rv2264c|M.tuberculosis_H37Rv TDVITPAP-TTPASAPPATTQPPATTQPPATTS-------PSPPPIPPIP
MMAR_3358|M.marinum_M QAPVTTQP-PATTEAPPATTQPPVTTEAPPTTQAPATQQLPTPPPIPPIP
MAV_2177|M.avium_104 ETPMTTTPRATPQAAPPAHPLPPRRVAAP---------------AIPPIP
: : . .
Mflv_0276|M.gilvum_PYR-GCK P-TVDPPDPIVTT-VIPDGGA-----------------------------
Mvan_0621|M.vanbaalenii_PYR-1 PTTVDPPDPVTTTVIIPEDGA-----------------------------
MSMEG_0692|M.smegmatis_MC2_155 D-VPDDPD------VPDDGGA-----------------------------
TH_4466|M.thermoresistible__bu --------------------------------------------------
MUL_0582|M.ulcerans_Agy99 PTTEAPGA------------------------------------------
MAB_2498c|M.abscessus_ATCC_199 SNRTSTTTTATSTPHP----------------------------------
Mb2287c|M.bovis_AF2122/97 PIPEIPQLP----PGIPQVPGIGQFSAISGS-------------------
Rv2264c|M.tuberculosis_H37Rv PIPEIPQLP----PGIPQVPGIGQFSAISGS-------------------
MMAR_3358|M.marinum_M QIPPIPQIPGIGFPQVPQVPQIPQVPQVPGVPGFGQVIAPQVIAPQVIAP
MAV_2177|M.avium_104 GLNEP--IP-----GLDRVNQI--IQEIEGNLGVG---------------
Mflv_0276|M.gilvum_PYR-GCK ------
Mvan_0621|M.vanbaalenii_PYR-1 ------
MSMEG_0692|M.smegmatis_MC2_155 ------
TH_4466|M.thermoresistible__bu ------
MUL_0582|M.ulcerans_Agy99 ------
MAB_2498c|M.abscessus_ATCC_199 ------
Mb2287c|M.bovis_AF2122/97 ------
Rv2264c|M.tuberculosis_H37Rv ------
MMAR_3358|M.marinum_M QAANGQ
MAV_2177|M.avium_104 ------