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MANGAGTALGLSIGATNLAAVTSDHAVTRKPVLTRYPDRPAEVGVPAENPRLQGPGVVITGFVNRVGDPR PVVASDGSVHRSEILLADALRALAYAATGGRALPDDIAVTYPAHWESAAVEALGAALGEIPEWSRRARPI VLIPDAAAALLAVRTSPGLPARGTVAVCDFGGSGTSITLMDADGDYRALAPTLRHRDFSGDVIDQALLGV VVANMPTTGAFPTGTAAIGSLSRLRGGCRVAKEQLSANTTTTLTDGLTGVRGEIRLTRAELDDAIAPALG GFVTVLRETLSRNGIRDLAAVVSTGGGANLPAVTTTLARHFRVPVATTPHPQLTAAVGAALRVAHADAGA TFTAPAAPATATARAAARPEPREDVTATAAVPPANPAPMEAQAWSDTGTDAAVPPPRRKRLFTRSRLFPT AAVVIAAAALLLVGTALMIGLTAQNKSDKSVTTPAPTLSTTPAPPPPSVTAEPAPPPADIPVPSTSDTNP PAETETPMTTTPRATPQAAPPAHPLPPRRVAAPAIPPIPGLNEPIPGLDRVNQIIQEIEGNLGVG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_2177 | - | - | 100% (555) | hypothetical protein MAV_2177 |
M. avium 104 | MAV_4816 | - | 8e-79 | 37.72% (570) | hypothetical protein MAV_4816 |
M. avium 104 | MAV_4824 | - | 9e-16 | 25.32% (391) | hypothetical protein MAV_4824 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2287c | - | 1e-137 | 50.50% (598) | hypothetical protein Mb2287c |
M. gilvum PYR-GCK | Mflv_0276 | - | 6e-88 | 38.20% (610) | hypothetical protein Mflv_0276 |
M. tuberculosis H37Rv | Rv2264c | - | 1e-137 | 50.50% (598) | hypothetical protein Rv2264c |
M. leprae Br4923 | MLBr_02501 | - | 9e-06 | 31.13% (151) | putative iron-sulphur-binding reductase |
M. abscessus ATCC 19977 | MAB_4291 | - | 1e-85 | 35.53% (608) | hypothetical protein MAB_4291 |
M. marinum M | MMAR_3358 | - | 1e-146 | 50.25% (601) | hypothetical protein MMAR_3358 |
M. smegmatis MC2 155 | MSMEG_4349 | - | 1e-109 | 44.27% (585) | hypothetical protein MSMEG_4349 |
M. thermoresistible (build 8) | TH_1245 | - | 1e-92 | 47.87% (422) | conserved hypothetical proline rich protein |
M. ulcerans Agy99 | MUL_1226 | - | 3e-74 | 34.36% (553) | hypothetical protein MUL_1226 |
M. vanbaalenii PYR-1 | Mvan_0621 | - | 3e-89 | 38.80% (598) | hypothetical protein Mvan_0621 |
CLUSTAL 2.0.9 multiple sequence alignment Mb2287c|M.bovis_AF2122/97 --MATGARPALGLSIGVTNLAAVA----------------AD-HSITRKP Rv2264c|M.tuberculosis_H37Rv --MATGARPALGLSIGVTNLAAVA----------------AD-HSITRKP MMAR_3358|M.marinum_M --MAEGARPALGLSIGATNLAAVT----------------AD-SAILRKP MAV_2177|M.avium_104 --MANGAGTALGLSIGATNLAAVT----------------SD-HAVTRKP MSMEG_4349|M.smegmatis_MC2_155 --MVDG----TGLSIGATNLTAVQ----------------VGRAAVTRSP TH_1245|M.thermoresistible__bu --MPDG----IGLSVGATTLAAVV----------------VGRTALTRTP Mflv_0276|M.gilvum_PYR-GCK --MTEP----LGLSIGTTNLVAAR----------------VGRPPVTRRA Mvan_0621|M.vanbaalenii_PYR-1 --MTEP----LGLSIGMTNLVAAR----------------VGRPPVTRRS MAB_4291|M.abscessus_ATCC_1997 --MANA----LGLSIGATQLVATPD--------------DPQSQPVVRSS MUL_1226|M.ulcerans_Agy99 --MYDP----LGLSIGTMNLVAAS----------------NGKPAVIRRS MLBr_02501|M.leprae_Br4923 MTTQMLIRMVLGLSMTAVVLLFAARRVLWLYKLTMSGQPANGRTDELGTR ***: * . Mb2287c|M.bovis_AF2122/97 VLTLYRQRPPE--------------------------------------- Rv2264c|M.tuberculosis_H37Rv VLTLYRQRPPE--------------------------------------- MMAR_3358|M.marinum_M VLTLYRQRPPE--------------------------------------- MAV_2177|M.avium_104 VLTRYPDRPAE--------------------------------------- MSMEG_4349|M.smegmatis_MC2_155 VLTRYPHRPSE--------------------------------------- TH_1245|M.thermoresistible__bu VLTRYPHRPPE--------------------------------------- Mflv_0276|M.gilvum_PYR-GCK ILTLVAGQAPQ--------------------------------------- Mvan_0621|M.vanbaalenii_PYR-1 ILNLYTDRAPE--------------------------------------- MAB_4291|M.abscessus_ATCC_1997 ILTLHEDGPPE--------------------------------------- MUL_1226|M.ulcerans_Agy99 VLTLYPHCAPK--------------------------------------- MLBr_02501|M.leprae_Br4923 IWTQITEVFGQRRLLQWSLPGLTHLFTMWGFFILLTVYIEAYGVLFQPNF : . : Mb2287c|M.bovis_AF2122/97 ----------VGVPSENPRLDEPGLVITDFVDRVGDSVGIVAADGSVYRS Rv2264c|M.tuberculosis_H37Rv ----------VGVPSENPRLDEPGLVITDFVDRVGDSVGIVAADGSVYRS MMAR_3358|M.marinum_M ----------IGLPSENPRLDQSGLVISDFVDRVGDQIGIVAADGSVHRS MAV_2177|M.avium_104 ----------VGVPAENPRLQGPGVVITGFVNRVGDPRPVVASDGSVHRS MSMEG_4349|M.smegmatis_MC2_155 ----------VGVPGENPNLTERGLILTDFVDRVGDPVGIVAADGSSHRG TH_1245|M.thermoresistible__bu ----------VGVPSENPQLTERGLIITDFVDRVGDPVGIVAPDGSTHPG Mflv_0276|M.gilvum_PYR-GCK ----------VGTPEENAGNNPSGVVLTGFVDRVGDPVPLIAEDGSAHRG Mvan_0621|M.vanbaalenii_PYR-1 ----------VGAPSEIPGFSQPRLVLSGFVERVGDPVPLVAADGSAHRG MAB_4291|M.abscessus_ATCC_1997 ----------VGVP------SQPGLTLTGFVGRVGDPVGIVAADGSVHRA MUL_1226|M.ulcerans_Agy99 ----------IGVLGENPSLDQPGTFMSGFVERIGDSVALVSPDGSAHDP MLBr_02501|M.leprae_Br4923 HLPIIGRWNAIGFLQDFFALAVLTSTVTFAIIRMRNEPKEYGRKSRFYGS :* :: : *: : . .. : Mb2287c|M.bovis_AF2122/97 EA--------------------------LVADALL---------ALAYTA Rv2264c|M.tuberculosis_H37Rv EA--------------------------LVADALL---------ALAYTA MMAR_3358|M.marinum_M EA--------------------------LVADALR---------ALAYTA MAV_2177|M.avium_104 EI--------------------------LLADALR---------ALAYAA MSMEG_4349|M.smegmatis_MC2_155 EV--------------------------LLAEALG---------ALLAAL TH_1245|M.thermoresistible__bu EA--------------------------VLADALH---------ALWRTV Mflv_0276|M.gilvum_PYR-GCK EQ--------------------------VLAAAL------------DAMA Mvan_0621|M.vanbaalenii_PYR-1 EQ--------------------------TLAQAL------------DAMA MAB_4291|M.abscessus_ATCC_1997 EW--------------------------ALTEAMRV-------LIADAVS MUL_1226|M.ulcerans_Agy99 DL--------------------------LMVEALD----------AMVVA MLBr_02501|M.leprae_Br4923 HTGGAWLILFMIFNVIWTYAVFRGASVDALGEAFPYNSGAFFSHAIAAVL . : *: Mb2287c|M.bovis_AF2122/97 TGGRALPGSVTVTYPAHWGPAAVAALDSALRRASEWSHGTSSTAQPLSLL Rv2264c|M.tuberculosis_H37Rv TGGRALPGSVTVTYPAHWGPAAVAALDSALRRASEWSHGTSSTAQPLSLL MMAR_3358|M.marinum_M TGGHTLPASTAVAYPAHWTTSAVDALGAALGRVPEWSP----AGQPLLLI MAV_2177|M.avium_104 TGGRALPDDIAVTYPAHWESAAVEALGAALGEIPEWSR----RARPIVLI MSMEG_4349|M.smegmatis_MC2_155 T-RGRPAGPVVVTHPAHWRPDQVEALRAALDAE----------LSGAPMI TH_1245|M.thermoresistible__bu APLGSPDDPIGVAHPAHWQPVAVEALRGRLAAQRDQAP----VLAQAPLV Mflv_0276|M.gilvum_PYR-GCK RLVDGGSPVAIA-VPSHWGPGTVGALRGALRTVPSLSP----GGVPATLI Mvan_0621|M.vanbaalenii_PYR-1 GLVDGGAPVAIA-VPAHWGPGTVGALRGALRAAPRLSP----NGIPPALI MAB_4291|M.abscessus_ATCC_1997 SANFTAPPVLSASIPAHWSPQTVSTLRDAIDRVPAFAP----GGRQLKLI MUL_1226|M.ulcerans_Agy99 AGADSSSSEIVIAVPAHWKPTAVQALRNGLRTHVGFVR----SGMAPRLV MLBr_02501|M.leprae_Br4923 YPLGQGANQIIETVALLLHIGVMLAFLLIVLHSKHLHIFLAPINVTFKRL . : :: : : Mb2287c|M.bovis_AF2122/97 PDAAAALYAIRAD--------------------PGIPARGIVAVCDFGGS Rv2264c|M.tuberculosis_H37Rv PDAAAALYAIRAD--------------------PGIPARGIVAVCDFGGS MMAR_3358|M.marinum_M PDAAAALFAARAN--------------------PGIPARGVVAVCDFGGS MAV_2177|M.avium_104 PDAAAALLAVRTS--------------------PGLPARGTVAVCDFGGS MSMEG_4349|M.smegmatis_MC2_155 ADATAALAALQDD--------------------PGVPARGVIAVCDFGGS TH_1245|M.thermoresistible__bu SDAEAALTALQAD--------------------PGLPTSGIVALCDFGGT Mflv_0276|M.gilvum_PYR-GCK PDSTAALASLRVS--------------------PGLPGSGVVVLVDLGGS Mvan_0621|M.vanbaalenii_PYR-1 PDATAALAALRVT--------------------PGLPSQGVVVLVDLGGS MAB_4291|M.abscessus_ATCC_1997 PDARAALEALAAG--------------------PGTPDRGVVVVCDLGGS MUL_1226|M.ulcerans_Agy99 PDAVAAMAAANSE--------------------LGIPADGVVGLLDFGAS MLBr_02501|M.leprae_Br4923 PDGLGPLMPMESDGEPINFEDPSEDAVFGRGKIEDFTWKAMLDFATCTEC .*. ..: . . . . : . Mb2287c|M.bovis_AF2122/97 GTGITLVDAADEYRPVAATVRHQAFSGDLIDQS---LLSYVMSELPGTGA Rv2264c|M.tuberculosis_H37Rv GTGITLVDAADEYRPVAATVRHQAFSGDLIDQS---LLSYVMSELPGTGA MMAR_3358|M.marinum_M GTSITLADASGEYQPLGATVRHPDFSGDLIDQS---LLTYVMSEMPATGS MAV_2177|M.avium_104 GTSITLMDADGDYRALAPTLRHRDFSGDVIDQA---LLGVVVANMPTTGA MSMEG_4349|M.smegmatis_MC2_155 GTSITLADADNGYQPIA-TVRHPDLSGALIDQA---LLTHVVDDLSAAGT TH_1245|M.thermoresistible__bu GTSLTIADAADGYRPVAPTLRHLDLSGELIDQA---LLRHVLADLTEAGV Mflv_0276|M.gilvum_PYR-GCK GSSVTLADAGANLVVVGQTVRYPEFSGDGIDRA---LLDHVLAGVSDTGQ Mvan_0621|M.vanbaalenii_PYR-1 GSSITLADAGSGAATIGQTVRYPDFSGEAIDQA---LLGHVLTGIADADT MAB_4291|M.abscessus_ATCC_1997 GSSITLADAARGFQQIGQTIRFADFSGQQIDQM---LLTQVLTDLNQD-- MUL_1226|M.ulcerans_Agy99 ASYVTLMEAKSDFEPVCATMRYEDFSGNQIDQA---LMLHVIEELGPNGV MLBr_02501|M.leprae_Br4923 GRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEKTAEKLEGLNL . : * : .: : . : : * . : Mb2287c|M.bovis_AF2122/97 FD---PAGTSAIGSLTKLRIECRKAKERLSSSTVT--------------- Rv2264c|M.tuberculosis_H37Rv FD---PAGTSAIGSLTKLRIECRKAKERLSSSTVT--------------- MMAR_3358|M.marinum_M FD---PSGTSAIGSLNRLRAECRQAKEQLSLSTVA--------------- MAV_2177|M.avium_104 F----PTGTAAIGSLSRLRGGCRVAKEQLSANTTT--------------- MSMEG_4349|M.smegmatis_MC2_155 ID---LTGTSAIGSLSRLRAECRRAKERLSTESAT--------------- TH_1245|M.thermoresistible__bu VD---ASGTSAIGSLSRLRAQCRTAKERLSTTAVT--------------- Mflv_0276|M.gilvum_PYR-GCK AD---TAGTAAVGPLMRLREECRAAKERLSSETAT--------------- Mvan_0621|M.vanbaalenii_PYR-1 ADPAGTAGTAAVGPLSRLRDECRAAKERLSGETAT--------------- MAB_4291|M.abscessus_ATCC_1997 -----PEGTTSVGALTRLRDQCRLAKERLSGDTAT--------------- MUL_1226|M.ulcerans_Agy99 D----QAGTAAASQLGLLREQCRAAKERLSIDAVT--------------- MLBr_02501|M.leprae_Br4923 ETTKDKSRHVPESGFGRVPGHGPEQATRPLVGTAEQGGVIDPDVLWSCVT . . : : : :. Mb2287c|M.bovis_AF2122/97 --------TLTDALG---GDIRLTRNELEDTIRDSLDSVGRALEQTLARS Rv2264c|M.tuberculosis_H37Rv --------TLTDALG---GDIRLTRNELEDTIRDSLDSVGRALEQTLARS MMAR_3358|M.marinum_M --------TLSDALPGVSGEVRLTRNELDETIRDSLDGFARVVEHTLQRA MAV_2177|M.avium_104 --------TLTDGLTGVRGEIRLTRAELDDAIAPALGGFVTVLRETLSRN MSMEG_4349|M.smegmatis_MC2_155 --------HLVAELPGHRSDVRLTRTELDEVLRAPLADFVAVLQDTLERN TH_1245|M.thermoresistible__bu --------TLTAEAPGRPHELRLTRDELDAVLRPPLDEFLTAVQYTLDRN Mflv_0276|M.gilvum_PYR-GCK --------AVPVDLPGFRSEVRVTRPELEQMIAGPLDGLLSLIDDTLTRN Mvan_0621|M.vanbaalenii_PYR-1 --------AVPVELPGFSSDVRVTRPELEQLISEPLTGLLSAIDDVLQRN MAB_4291|M.abscessus_ATCC_1997 --------SVPVQLPGITTDVRLTRAELEGHLRGPLSNLINAIQDTVERN MUL_1226|M.ulcerans_Agy99 --------ELAVDLAGSAATIEVTRDQLEDLIQDQLTGFVYAFDDLLARN MLBr_02501|M.leprae_Br4923 CGACVEQCPVDIEHIDHIIDMRRYQVMMESEFPSELSTLFKNLETKGNPW : :. : :: : * . . Mb2287c|M.bovis_AF2122/97 GIRTAELVAIVSVG---------------GGANIPAVTTTLSGRFCVPVV Rv2264c|M.tuberculosis_H37Rv GIRTAELVAIVSVG---------------GGANIPAVTTTLSGRFCVPVV MMAR_3358|M.marinum_M GVPAADLVAIVTVG---------------GGANIPSVTTTLSGRFGVPVI MAV_2177|M.avium_104 GIR--DLAAVVSTG---------------GGANLPAVTTTLARHFRVPVA MSMEG_4349|M.smegmatis_MC2_155 GIHPGALAAVATIG---------------GGARIPAVTTTLSEHLRVPVI TH_1245|M.thermoresistible__bu GIRPSDLTAVATVG---------------GGARIPLITAALSERFRVPVV Mflv_0276|M.gilvum_PYR-GCK GVATENISAIATVG---------------GGAAIPLVTQRLSERLRAPVV Mvan_0621|M.vanbaalenii_PYR-1 GIAAGDVSAVATVG---------------GGAAIPLVTQRLSERLRAPVV MAB_4291|M.abscessus_ATCC_1997 GIHPANITAVASVG---------------GGASIPLVTQQLSERMRVPVI MUL_1226|M.ulcerans_Agy99 NASWADLSAVVTVG---------------GGASIPLVTQRLSVHTRLPVL MLBr_02501|M.leprae_Br4923 GQNAGDRTNWIDEVDFDVPVYGEDVDSFDGYEYLFWVGCAGAYDDKAKKT . * : : : Mb2287c|M.bovis_AF2122/97 RTPRPQLTAAFGG---ALWAARRPGDTSATVLTA---VTSAT-------- Rv2264c|M.tuberculosis_H37Rv RTPRPQLTAAFGG---ALWAARRPGDTSATVLTA---VTSAT-------- MMAR_3358|M.marinum_M TAPRPQLTAATGG---ALRAARGPGDSSATVLTS---AAPMTQTAMAPLD MAV_2177|M.avium_104 TTPHPQLTAAVGA---ALRVAH--ADAGATFTAP---AAPAT-------- MSMEG_4349|M.smegmatis_MC2_155 TAPHPELTAAIGGGLIAVRGTVR---DDATALAP---AAPVPAETGEGTG TH_1245|M.thermoresistible__bu TTPQPELTAAIGAGLTAVRALQAGPADEATQWAA---AVPDQADTQLWDG Mflv_0276|M.gilvum_PYR-GCK TTPQALLNIGAGAALIAN--QTLDADAPTGMAPTGMAAAADVPTAMGPAV Mvan_0621|M.vanbaalenii_PYR-1 TTPEPALNVAAGAALVAN--QSLATDAPTGMAP-----AADAPTAMGHAA MAB_4291|M.abscessus_ATCC_1997 TAPQPQLAAARGVALLATR-PDLPPQDATAMRP-----VEQPPGDATMMR MUL_1226|M.ulcerans_Agy99 AVPEPACAAANGALALAARGKELDFRTRTSIGLP----AASAATAATTVI MLBr_02501|M.leprae_Br4923 TKAVAELLAIAGVKYLVLGTGETCNGDSAHRSGNEFLFQQLAAQAVEILD . . * . : Mb2287c|M.bovis_AF2122/97 ----ATAPADAPASVLQP------ALAWSEADEDSHIGP--------APG Rv2264c|M.tuberculosis_H37Rv ----ATAPADAPASVLQP------ALAWSEADEDSHIGP--------APG MMAR_3358|M.marinum_M PDVGAVAAADAPVSALQP------ALAWSEADDQSRAMPVVGDDYSGASG MAV_2177|M.avium_104 ----ATARAAARPEPRED------VTATAAVPPAN-------------PA MSMEG_4349|M.smegmatis_MC2_155 TATMAAALMAPEPPAAPQ------ALAWSDADDVPDVAP--PDEYVDDSA TH_1245|M.thermoresistible__bu ADQPGSDQLGADPTGAAP------ALAWSQADDVPEVS----DVYAPXXX Mflv_0276|M.gilvum_PYR-GCK DAPTALGPAAPPVAGG--------ALAWSQDDDG-VQDPLPYTG----AD Mvan_0621|M.vanbaalenii_PYR-1 WAAGAAGLAATESAGDGASSATFRALAWSQDDDA-AGDPLPYTG----ED MAB_4291|M.abscessus_ATCC_1997 PVPTGTGTFAAPVAAAANEEP---ELAWSQDDSAPDLAPLQETGY--QSG MUL_1226|M.ulcerans_Agy99 EPPAGDVMVIDQDALTDR------ELAWSQTDFP-SEGLVRFEG----DS MLBr_02501|M.leprae_Br4923 GLFEGVNSVDRKIVVTCPHCFNTIGKEYRQLGGNYTVLHHTQLLNWLVHD . Mb2287c|M.bovis_AF2122/97 YTAARP--------SLSFDHDAHAEPE--------PKSPPIPWYR-LPAV Rv2264c|M.tuberculosis_H37Rv YTAARP--------SLSFDHDAHAEPE--------PKSPPIPWYR-LPAV MMAR_3358|M.marinum_M YTSARP--------QLTFEENARAEPA--------PKSVVIPWYR-LPGV MAV_2177|M.avium_104 PMEAQA--------WSDTGTDAAVPPP--------RRKRLFTRSRLFPTA MSMEG_4349|M.smegmatis_MC2_155 GSSVYG--------PRPQ-VQFADPEP--------DAAAAQPWYRRRGAV TH_1245|M.thermoresistible__bu XRSLYA--------RCPAPVRHAWRLT--------DRTVRAASADRVPGL Mflv_0276|M.gilvum_PYR-GCK YTSPAG--YGDA--ATGARPPVAFAPG---DDGYSDDLPPLPWYKRPPVL Mvan_0621|M.vanbaalenii_PYR-1 YTVAGG--YADP--GTAARPSVDFAGQ---DDTYTDELAPLPWYKRPPVL MAB_4291|M.abscessus_ATCC_1997 YTVDLDDEYQGPTEATTARPELRFSHGPYADEDDYDDYPPLPWYRRPLVW MUL_1226|M.ulcerans_Agy99 YSEEGP--------CWSMRLNMIEPLK----------EPAWRRFRVSQVL MLBr_02501|M.leprae_Br4923 KKLVPVT-------PVSQDITYHDPCYLGRHNKVYEAPRELVRAAGANFT Mb2287c|M.bovis_AF2122/97 IITGTTVAVLLVG--AAVAIGLSTG-------------DQPTAPGTPQRP Rv2264c|M.tuberculosis_H37Rv IITGTTVAVLLVG--AAVAIGLSTG-------------DQPTAPGTPQRP MMAR_3358|M.marinum_M IIVATVVAVLLVG--AAVAIALSSG-------------EQP-ATRSPEAT MAV_2177|M.avium_104 AVVIAAAALLLVG--TALMIGLTAQ-------------NKSDKSVTTPAP MSMEG_4349|M.smegmatis_MC2_155 VGAGAAAVVAVIA--AVALAVTRDD-------------GDVAVPASTSTP TH_1245|M.thermoresistible__bu AAEAALFTLISLP--ALLLAVFGSL-------------GYIAEALGPDGT Mflv_0276|M.gilvum_PYR-GCK FGLAAAAALLAVGGLAVTLTSSEG-------------STTVTETASTTAP Mvan_0621|M.vanbaalenii_PYR-1 FGVAAAAALLAAGGLAVTLTGSQGD------------SGTVTETAS--VP MAB_4291|M.abscessus_ATCC_1997 FIAAAAVAGIAFTGMMVSLTSSESP------------APATTTPSVNVVP MUL_1226|M.ulcerans_Agy99 IGLSAVVAMTAIGGVAFTLTAIERRQSPVVPSVGPLPAPSRSIAASSAPP MLBr_02501|M.leprae_Br4923 EMPRHAERSFCCGAGGARMWMEEHIGKRINHERVDEALATNATTIATACP . . Mb2287c|M.bovis_AF2122/97 GVTTTAAPPPSPAPASDGPTTEPAPPVQAPATGGP--------------- Rv2264c|M.tuberculosis_H37Rv GVTTTAAPPPSPAPASDGPTTEPAPPVQAPATGGP--------------- MMAR_3358|M.marinum_M TSPPTSAPAAVP-PVTDAGTSAPAPSTQPPASQEP--------------- MAV_2177|M.avium_104 TLSTTPAPPPPS------------------VTAEP--------------- MSMEG_4349|M.smegmatis_MC2_155 VTTTEEVPPPPPPEAVDQPA--PVQTVTEVLP------------------ TH_1245|M.thermoresistible__bu EGLRRLVLDVPQSFLTEETFGFYAVMVEDVLTRRRGSVVSIGLLLSLWTG Mflv_0276|M.gilvum_PYR-GCK SDTTPVELPPPVTTVTIGPDGVATTTVSQPPPP----------------- Mvan_0621|M.vanbaalenii_PYR-1 TETPPAELPPPVTTVTVGADGIATTTVSQPPPP----------------- MAB_4291|M.abscessus_ATCC_1997 STGDAPAEPPPSPEPPPPPQTHTVTQSVQPPPPSP--------------- MUL_1226|M.ulcerans_Agy99 KALEPSFVPPPASAARAPSAAPAPTSVAPPPPP----------------- MLBr_02501|M.leprae_Br4923 FCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGSLDYDKAKLPAKGTAAA Mb2287c|M.bovis_AF2122/97 ---------APPLQQPLPPPPTTTN------------TQPAVTTDVITPA Rv2264c|M.tuberculosis_H37Rv ---------APPLQQPLPPPPTTTN------------TQPAVTTDVITPA MMAR_3358|M.marinum_M ---------APPPTQQAPPPPSTEA------------PPPSTTQAPVTTQ MAV_2177|M.avium_104 ---------APPPAD-IPVPSTSDT------------NPPAETETPMTTT MSMEG_4349|M.smegmatis_MC2_155 --------APETVVQTVPPPPVEQP-----------AEPPAETPPPTTEA TH_1245|M.thermoresistible__bu SRAVNRYLETITIAYGVAPRPVWRRRLIALGLTAGGLVGAAAVLPPLVVG Mflv_0276|M.gilvum_PYR-GCK ------PPSSTSSTTTTTPSSSTTT------------TTTTTTTTTTTTT Mvan_0621|M.vanbaalenii_PYR-1 ------PPSSSTTTPTTASTTSPTT------------TTTTTTTTTTTTT MAB_4291|M.abscessus_ATCC_1997 -----EPPPPPPPTTTTTTTPPTTT------------TTTTTTTTTTTTT MUL_1226|M.ulcerans_Agy99 ------PRPVATATTTVAPPVTTTK------------TTVPPTTAATTTP MLBr_02501|M.leprae_Br4923 EITKTAGLSPAKPTESEAPAPEKST--------QAAASAAPAKGIRLAAG . . . Mb2287c|M.bovis_AF2122/97 P-TTPASAPPATTQPPATTQPPATTS----------------PSPPPIPP Rv2264c|M.tuberculosis_H37Rv P-TTPASAPPATTQPPATTQPPATTS----------------PSPPPIPP MMAR_3358|M.marinum_M P-PATTEAPPATTQPPVTTEAPPTTQAP---------ATQQLPTPPPIPP MAV_2177|M.avium_104 PRATPQAAPPAHPLPPRRVAAP------------------------AIPP MSMEG_4349|M.smegmatis_MC2_155 PPPTSEAPPTTEAPTTTEAPTTT-------------------EAPTSTPP TH_1245|M.thermoresistible__bu PQLVQELAPPAMRAATVQMLDAMFWPALILAILVGLVSFYHFGVPWQTPW Mflv_0276|M.gilvum_PYR-GCK NTAPTTTTTRTTTAPPTTTPPPTTTQ------------------APPPPT Mvan_0621|M.vanbaalenii_PYR-1 -----TTTTRTTTTQPTTTAPPTTTQ------------------PPPPTT MAB_4291|M.abscessus_ATCC_1997 -----TTTPTTTTTQPTTTTTQPTST------------------SRPAIT MUL_1226|M.ulcerans_Agy99 ----TTTPPPTTTAPPTTTAPPSTTSTVKM-------TTEWLHVPLLPIP MLBr_02501|M.leprae_Br4923 AKQPDAKKPVSQTTSAKATEAPAATVPVKG---------LGIAGGAKRPG . : . Mb2287c|M.bovis_AF2122/97 IPPIPEIPQLP------------------------------PGIPQVPGI Rv2264c|M.tuberculosis_H37Rv IPPIPEIPQLP------------------------------PGIPQVPGI MMAR_3358|M.marinum_M IPQIPPIPQIPGIGF--------------------------PQVPQVPQI MAV_2177|M.avium_104 IPGLNEP--IP-------------------------------GLDRVNQI MSMEG_4349|M.smegmatis_MC2_155 R---------------------------------------------WSPT TH_1245|M.thermoresistible__bu RRDLPGAVLAMVLWLLASAGLRAYLAVSVRDEAVYAQLAVPIAVVLWLYV Mflv_0276|M.gilvum_PYR-GCK TEEPPP-TVDPP-----------------------------------DPI Mvan_0621|M.vanbaalenii_PYR-1 TAAPPPTTVDPP-----------------------------------DPV MAB_4291|M.abscessus_ATCC_1997 IPGLPPIPIGPR-----------------------------------N-- MUL_1226|M.ulcerans_Agy99 IPIRVPASQAPP-----------------------------------SPV MLBr_02501|M.leprae_Br4923 AKKSPDQAETPAP---------------------------------TESK Mb2287c|M.bovis_AF2122/97 GQFSAISGS------------------------------------ Rv2264c|M.tuberculosis_H37Rv GQFSAISGS------------------------------------ MMAR_3358|M.marinum_M PQVPQVPGVPGFGQVIAP------QVIAPQVIAPQAANGQ----- MAV_2177|M.avium_104 --IQEIEGNLGVG-------------------------------- MSMEG_4349|M.smegmatis_MC2_155 APYPTIPG---------------LPWVP----APQVPGGQAG--- TH_1245|M.thermoresistible__bu TAFAVLVGAEFNAEIERMWPHDRYPWRLRRRRDRRSRDGSARMGR Mflv_0276|M.gilvum_PYR-GCK VTT-VIPDGGA---------------------------------- Mvan_0621|M.vanbaalenii_PYR-1 TTTVIIPEDGA---------------------------------- MAB_4291|M.abscessus_ATCC_1997 --------------------------------------------- MUL_1226|M.ulcerans_Agy99 SQNPGPQNPFMSPGTP----------------------------- MLBr_02501|M.leprae_Br4923 SEAKPEPSDHADGNPAPPTAPVKRLGITRSARPPGKH--------