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VSDTSDESRRPRKLDPVSAEVQFDRLAATAGQLLKAGSRILSQRPTERDLRQVVAKEMRRSFAELGPAYV KFGQLIASSPGMFPEDLSAEFRSLLDQVPPADPQTIRSMLSNELGASPENVFGSFDEVPFASASIAQVHR ATLKDGTAVVVKIQRPAIRTRLAADLQILKQIARGLELTEMGRMSNIYEVMRDFESNLAEELDFSLEARA MRDWTAGLAGSRYASKVRVPEIYSDLCTDKVLTMEYVEGIRIDDADAIRAAGFDGPEVVKTLMLTLFDSA FTAGTFHGDLHAGNLMVDPHGRIVFLDFGIVGRLDQRTRKTLRELIGALILEPDDEAAARTLIKLGAIDA HADPARVAESLRKVTRPMGTSLGKISYGTIGRQLTALGREHDAILPKEFILVGKQLLYVERYTKLLAPDW QPVGDPEILTYFGTLIAEYQQAREEIKHSKNDTDGLGE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2391 | - | - | 100% (458) | hypothetical protein MAB_2391 |
| M. abscessus ATCC 19977 | MAB_2393c | - | e-125 | 52.48% (444) | hypothetical protein MAB_2393c |
| M. abscessus ATCC 19977 | MAB_3879 | - | e-120 | 51.49% (435) | hypothetical protein MAB_3879 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0666c | - | 1e-121 | 50.57% (441) | hypothetical protein Mb0666c |
| M. gilvum PYR-GCK | Mflv_5111 | - | 1e-121 | 49.33% (450) | hypothetical protein Mflv_5111 |
| M. tuberculosis H37Rv | Rv0647c | - | 1e-121 | 50.79% (441) | hypothetical protein Rv0647c |
| M. leprae Br4923 | MLBr_01898 | - | 1e-119 | 49.77% (442) | hypothetical protein MLBr_01898 |
| M. marinum M | MMAR_0982 | - | 1e-121 | 49.02% (459) | hypothetical protein MMAR_0982 |
| M. avium 104 | MAV_4514 | - | 1e-126 | 51.92% (443) | ABC1 family protein |
| M. smegmatis MC2 155 | MSMEG_1353 | - | 1e-119 | 49.20% (439) | ABC1 family protein |
| M. thermoresistible (build 8) | TH_3124 | - | 1e-126 | 51.36% (442) | PUTATIVE ABC-1 domain protein |
| M. ulcerans Agy99 | MUL_0734 | - | 1e-120 | 48.37% (459) | hypothetical protein MUL_0734 |
| M. vanbaalenii PYR-1 | Mvan_1241 | - | 1e-121 | 50.69% (434) | hypothetical protein Mvan_1241 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0666c|M.bovis_AF2122/97 MRAEIGPDFRPHYTFGDAYPASERAHVNWELSAPVWHTAQMGSTTHREVA
Rv0647c|M.tuberculosis_H37Rv MRAEIGPDFRPHYTFGDAYPASERAHVNWELSAPVWHTAQMGSTTHREVA
MAV_4514|M.avium_104 ------------------------------------------------MA
MMAR_0982|M.marinum_M ----------------------------------------MTTTKHREVA
MUL_0734|M.ulcerans_Agy99 ------------------------------MTLSIWHTAQMTTTKHREVA
MLBr_01898|M.leprae_Br4923 ----------------------------------------MSSTNNHQVV
Mflv_5111|M.gilvum_PYR-GCK ----------------------------------MSSTQRNQRTPHRAVA
Mvan_1241|M.vanbaalenii_PYR-1 ----------------------------------MTAP-RN--TPHRDVA
MSMEG_1353|M.smegmatis_MC2_155 ----------------------------------MSTTPAK--TKHREVA
TH_3124|M.thermoresistible__bu ----------------------------------MSTT------KHREVA
MAB_2391|M.abscessus_ATCC_1997 --------------------------------------MSDTSDESRRPR
Mb0666c|M.bovis_AF2122/97 KLDRVPLPVEAARVAATGWQVTRTAVRFIGRLPRKG---PWQQKVIKELP
Rv0647c|M.tuberculosis_H37Rv KLDRVPLPVEAARVAATGWQVTRTAVRFIGRLPRKG---PWQQKVIKELP
MAV_4514|M.avium_104 KLDRVPLPVEAARVAATGWQVTRSAARVLTKLPAKG---PWQQKVIKQLP
MMAR_0982|M.marinum_M KLDRVPLPVEAARVAVTGWQVTRTAARFVTKLPGKGFASSWQQKIIKEIP
MUL_0734|M.ulcerans_Agy99 KLDRVPLPVEAARVAVTGWQVTRTAARFVTKLPGKGFASSWQQKIIKEIP
MLBr_01898|M.leprae_Br4923 KLDRVPLPVEAARIAATYWQITRAAARVATKLAGKG---PWQQKVIREIP
Mflv_5111|M.gilvum_PYR-GCK RLDRVPLPMEAARIGVTGWQITRTGGRVLSSLTTRG---TLQQKVVKQIP
Mvan_1241|M.vanbaalenii_PYR-1 RLDRVPIPAEAARIGATGWQITRTGARVVTKLAGRG---SLQQKIVKEIP
MSMEG_1353|M.smegmatis_MC2_155 RLDRVPLPAEAARIGATGWQITRTGARVAANIFGRG---SLQQKIVKQVP
TH_3124|M.thermoresistible__bu KLDRVSLPVEAARIGATGWQIARTGARVVTRLPSRG---SLQQKVIKELP
MAB_2391|M.abscessus_ATCC_1997 KLDPVSAEVQFDRLAATAGQLLKAGSRILSQRPTER---DLRQVVAKEMR
:** *. : *:..* *: ::. *. . :* : :::
Mb0666c|M.bovis_AF2122/97 QTFADLGPTYVKFGQIIASSPGAFGESLSREFRGLLDRVPPAKTDEVHKL
Rv0647c|M.tuberculosis_H37Rv QTFADLGPTYVKFGQIIASSPGAFGESLSREFRGLLDRVPPAKTDEVHKL
MAV_4514|M.avium_104 QTFADLGPTYVKFGQIIASSPGAFGESLSREFRGLLDRVPPADPDEVHKL
MMAR_0982|M.marinum_M QTFADLGPTYVKFGQIIASSPGAFGESLSREFRGLLDRVPPADTDQVHKL
MUL_0734|M.ulcerans_Agy99 QTFVDLGPTYVKFGQIIASSPGAFGESLSREFRGLLDRVPPADTDQVHKL
MLBr_01898|M.leprae_Br4923 QTFANLGPTYVKFGQIIASSPSAFGESLAREFRGLLDQVPPADTNEVHKL
Mflv_5111|M.gilvum_PYR-GCK QAFADLGPTYVKFGQIIASSPGAFGEPLSREFRGLLDRVPPADSDAVHKL
Mvan_1241|M.vanbaalenii_PYR-1 QAFADLGPTYVKFGQIIASSPGAFGEPLSREFRSLLDRVPPADTTAVHKL
MSMEG_1353|M.smegmatis_MC2_155 KTFSDLGPTYVKFGQIIASSPGAFGEPLSREFRGLLDRVPPANPDEVQKL
TH_3124|M.thermoresistible__bu KTFSDLGPTYVKFGQIIASSPGAFGEPLSREFRSLLDRVPPADPTAVRKL
MAB_2391|M.abscessus_ATCC_1997 RSFAELGPAYVKFGQLIASSPGMFPEDLSAEFRSLLDQVPPADPQTIRSM
::* :***:******:*****. * * *: ***.***:****.. ::.:
Mb0666c|M.bovis_AF2122/97 FVEELGDEPARLFASFEEEPFASASIAQVHYATLRSGEEVVVKIQRPGIR
Rv0647c|M.tuberculosis_H37Rv FVEELGDEPARLFASFEEEPFASASIAQVHYATLRSGEEVVVKIQRPGIR
MAV_4514|M.avium_104 FLEELGADPSELFASWDETPFASASIAQVHYATLHTGEEVVVKIQRPGIR
MMAR_0982|M.marinum_M FVEELGAEPAELFAAFEEEPFASASIAQVHYATLKTGEEVVVKIQRPGIR
MUL_0734|M.ulcerans_Agy99 FVEELGTEPAELFATFEEEPFASASIAQVHYATLKTGEEVVVKIQRPGIR
MLBr_01898|M.leprae_Br4923 FVEELGDAPSKLFASFSEEPFASASIAQVHSAILHSGEHVVVKIQRPGIR
Mflv_5111|M.gilvum_PYR-GCK LREDLGDEPQNLFKSFDEKPFASASIAQVHYATLHSGEEVVVKIQRPGIR
Mvan_1241|M.vanbaalenii_PYR-1 FREELGDEPQNLFKSFDDKPFASASIAQVHYATLHSGEEVVVKIQRPGIR
MSMEG_1353|M.smegmatis_MC2_155 IREELGDDPHKLFKTFDDTPFASASIAQVHYATLHSGEEVVVKIQRPGIR
TH_3124|M.thermoresistible__bu VRQELGADPSELFKHFDDKPFASASIAQVHYATLHSGEEVVVKIQRPGIR
MAB_2391|M.abscessus_ATCC_1997 LSNELGASPENVFGSFDEVPFASASIAQVHRATLKDGTAVVVKIQRPAIR
. ::** * .:* :.: *********** * *: * ********.**
Mb0666c|M.bovis_AF2122/97 RRVAADLQILKRFAQTVELAKLGRRLSAQDVVADFADNLAEELDFRLEAQ
Rv0647c|M.tuberculosis_H37Rv RRVAADLQILKRFAQTVELAKLGRRLSAQDVVADFADNLAEELDFRLEAQ
MAV_4514|M.avium_104 RRVAADLQILKRFAQAVELAKLGRRLSAQDVVADFSDNLAEELNFRLEAQ
MMAR_0982|M.marinum_M RRVAADLQILQRFAQAVELAKLGRRLSAQDVVADFSDNLAEELDFRLEAQ
MUL_0734|M.ulcerans_Agy99 RRVAADLQILQRFAQAVELAKLGRRLSAQDVVADFSDNLAVELDFRLEAQ
MLBr_01898|M.leprae_Br4923 RRVAADLQILKRFAQAVELAKLGRRLSAQDVVADFSDNLAEELNFRLEAQ
Mflv_5111|M.gilvum_PYR-GCK RRVAADLQILKRGARLVEFAKLGQRLSAQDVVADFADNLAEELDFRLEAQ
Mvan_1241|M.vanbaalenii_PYR-1 RRVAADLQILKRGARLVEFAKLGQRLSAQDVVADFADNLAEELDFRLEAQ
MSMEG_1353|M.smegmatis_MC2_155 RRVAADLQILKRGARLVEFAKLGQRLSAQDVVADFADNLAEELDFRLEAQ
TH_3124|M.thermoresistible__bu RRVTADLQILKHGARLVELAKLGRRLSAQDVVADFADNLAEELDFRLEAQ
MAB_2391|M.abscessus_ATCC_1997 TRLAADLQILKQIARGLELTEMGRMSNIYEVMRDFESNLAEELDFSLEAR
*::******:: *: :*::::*: . :*: ** .*** **:* ***:
Mb0666c|M.bovis_AF2122/97 SMEAWVSHLHASPLGKNIRVPQVHWDFTTERVLTMERVHGIRIDNTAAIR
Rv0647c|M.tuberculosis_H37Rv SMEAWVSHLHASPLGKNIRVPQVHWDFTTERVLTMERVHGIRIDNAAAIR
MAV_4514|M.avium_104 SMEAWVSHLHASPLGKNIRVPQVYWDFTTDRVLTMERVSGIRIDDVAAVR
MMAR_0982|M.marinum_M SMDAWVAHLHASPLGRNIRVPQVHWNFTSERVLTMERVHGVRIDNVAAIR
MUL_0734|M.ulcerans_Agy99 SMDAWVAHLHASPLGRNIRVPQVHWNFTSERVLTMERVHGVRIDNVAAIR
MLBr_01898|M.leprae_Br4923 SMEAWGSYLHTSPLGKNIRVPKVHWEFTGERVLTMEQVHGIRIDNADAIR
Mflv_5111|M.gilvum_PYR-GCK SMDAWVAHMHSSPLGQNIRVPQVYWDLTSERVLTMERITGVRIDDVAAIR
Mvan_1241|M.vanbaalenii_PYR-1 SMDAWVAHMHASPLGRNIRVPQVYWDLTSERVLTMERVTGVRIDDVAAIR
MSMEG_1353|M.smegmatis_MC2_155 SMDAWVAHMHASPLGANIRVPTVYWDLTSERVLTMERITGVRIDDVAAIR
TH_3124|M.thermoresistible__bu SMDTWVAHMHASPLGKNIRVPQVYWDLTSERVLTMERVSGVRIDDVAALR
MAB_2391|M.abscessus_ATCC_1997 AMRDWTAGLAGSRYASKVRVPEIYSDLCTDKVLTMEYVEGIRIDDADAIR
:* * : : * . ::*** :: :: ::***** : *:***:. *:*
Mb0666c|M.bovis_AF2122/97 KAGFDGVELVKALLFSVFEGGLRHGLFHGDLHAGNLYVDEAGRIVFFDFG
Rv0647c|M.tuberculosis_H37Rv KAGFDGVELVKALLFSVFEGGLRHGLFHGDLHAGNLYVDEAGRIVFFDFG
MAV_4514|M.avium_104 KAGFDGVELVKALLFSLFEGGLRHGLFHGDLHAGNLYVDEAGRIVFFDFG
MMAR_0982|M.marinum_M KAGFDGTELVKALLFSVFEGGLRHGLFHGDLHAGNLYVDEEGRIVFFDFG
MUL_0734|M.ulcerans_Agy99 KAGFDGTELVKALLFSVFEGGLRHGLFHGDLHAGNLYVDEEGRIVFFDFG
MLBr_01898|M.leprae_Br4923 KSGFDGVELVKALLFSVFEGGLRHGLFHGDLHAGNLHVDDQGRIVFFDFG
Mflv_5111|M.gilvum_PYR-GCK KKGFDGEALVKALLFSVFEGGLRHGLFHGDLHAGNLYVDDDGKVVFFDFG
Mvan_1241|M.vanbaalenii_PYR-1 KKGFDGTELVKALLFSVFEGGLRHGLFHGDLHAGNLYVDDDGKIVFFDFG
MSMEG_1353|M.smegmatis_MC2_155 KKGFDGTELVKALLFSVFEGGLRHGLFHGDLHAGNLYVDDDGKIVFFDFG
TH_3124|M.thermoresistible__bu KKGFEGTELVKALLFSLFEGGLRHGLFHGDLHAGNLYVDDDGKIVFFDFG
MAB_2391|M.abscessus_ATCC_1997 AAGFDGPEVVKTLMLTLFDSAFTAGTFHGDLHAGNLMVDPHGRIVFLDFG
**:* :**:*::::*:..: * ********** ** *::**:***
Mb0666c|M.bovis_AF2122/97 IMGRIDPRTRWLLRELVYALLVKKDHAAAGKIVVLMGAVGTMKPETQAAK
Rv0647c|M.tuberculosis_H37Rv IMGRIDPRTRWLLRELVYALLVKKDHAAAGKIVVLMGAVGTMKPETQAAK
MAV_4514|M.avium_104 IMGRIDPRTRWLLRELVYALLVKKDHAAAGKIVVLMGAVGTVKPEAQAAK
MMAR_0982|M.marinum_M IMGRIDPRTRWLLRELVYALLVKKDHAAAGKIVVLMGAVGTMKPEAQAAK
MUL_0734|M.ulcerans_Agy99 IMGRIDPRTRWLLRELVYALLVKKDHAAAGKIVVLMGAVGTMKPEAQAAK
MLBr_01898|M.leprae_Br4923 IMGRIDPRTRWLLRELVFALLVKKDHAAAGKIVVLMGAVGTVKPEARAAK
Mflv_5111|M.gilvum_PYR-GCK IMGRIDPRTRWLLRELVYALLVKKDHAAAGKIVVLMGAVGTMRPEAEAAR
Mvan_1241|M.vanbaalenii_PYR-1 IMGRIDPRTRWLLRELVYALLVKKDHAAAGKIVVLMGAVGTMKPEAEAAK
MSMEG_1353|M.smegmatis_MC2_155 IMGRIDPRTRWLLRELVHALLVKKDHAAAGKIVVLMGAVGTVKPEGQAAK
TH_3124|M.thermoresistible__bu IMGRIDPRTRWLLRELVYALLVKKDHAAAGKIVVLMGAVGTTKPEAQAAK
MAB_2391|M.abscessus_ATCC_1997 IVGRLDQRTRKTLRELIGALILEPDDEAAARTLIKLGAIDAHADPARVAE
*:**:* *** ****: **::: *. **.: :: :**:.: ..*.
Mb0666c|M.bovis_AF2122/97 DLERFATPLTMQSLGDMSYADIGRQLSALADAYDVKLPRELVLIGKQFLY
Rv0647c|M.tuberculosis_H37Rv DLERFATPLTMQSLGDMSYADIGRQLSALADAYDVKLPRELVLIGKQFLY
MAV_4514|M.avium_104 DLEKFATPLTMQTLGDMSYADIGRQLSALADAYDVKLPRELVLIGKQFLY
MMAR_0982|M.marinum_M DLEKFATPLTMQSLGDMSYADIGRQLSALADAYDVKLPRELVLIGKQFLY
MUL_0734|M.ulcerans_Agy99 DLEKFATPLTMQSLGDMSYADIGRQLSALADAYDVKLPRELVLIGKQFLY
MLBr_01898|M.leprae_Br4923 DLENFTTPLAMKTLGDMSYTDIGRQLSALSDAYNVKLPRELVLIGKQFLY
Mflv_5111|M.gilvum_PYR-GCK DLEKFATPLTLKSLGDLSYAEIGKQLSTLADAYDVKLPRELVLIGKQFLY
Mvan_1241|M.vanbaalenii_PYR-1 DLEKFATPLTLKSLGDLSYAEIGKQLSALADAYDVKLPRELVLIGKQFLY
MSMEG_1353|M.smegmatis_MC2_155 DLEAFATPLTMKSLGDMSYAEIGRQLSALADAYDVKLPRELVLIGKQFLY
TH_3124|M.thermoresistible__bu DLEKFATPLTMSTLGDMSYAEIGRQLSALAEAYDVKLPRELVLIGKQFLY
MAB_2391|M.abscessus_ATCC_1997 SLRKVTRPMG-TSLGKISYGTIGRQLTALGREHDAILPKEFILVGKQLLY
.*. .: *: :**.:** **:**::*. ::. **:*::*:***:**
Mb0666c|M.bovis_AF2122/97 VERYMKLLAPRWQMMSDPQLTGYFANFMVEVSREH----------QSDIE
Rv0647c|M.tuberculosis_H37Rv VERYMKLLAPRWQMMSDPQLTGYFANFMVEVSREH----------QSDIE
MAV_4514|M.avium_104 VERYMKLLAPKWQMMSDPQLTGYFANFMVEVSREHSSEF------ESDVE
MMAR_0982|M.marinum_M VERYMKLLAPKWQMMSDPQLTGYFANFMVEVSREHQGDSSDASGDASDVE
MUL_0734|M.ulcerans_Agy99 VERYMKLLAPKWQMMSDPQLTGYFANFMVEVSREHQGDSSDASGDASDVE
MLBr_01898|M.leprae_Br4923 VERYMKLLAPEWQIMLDPELTGYFANFMVEVSREH----------QSDVE
Mflv_5111|M.gilvum_PYR-GCK VERYMKLLAPKWQMMSDPALTGYFANFMVEVSREHS-------DTGPDA-
Mvan_1241|M.vanbaalenii_PYR-1 VERYMKLLAPKWQMMSDPALTGYFANFMVEVSREHS-------DDVEA--
MSMEG_1353|M.smegmatis_MC2_155 VERYMKLLAPKWQMMSDPQLTGYFANFMVEVSREHK-------EIDDVDE
TH_3124|M.thermoresistible__bu VERYMKLLAPKWQMMSDPELTGYFANFMVDIKREHD-------AKADELE
MAB_2391|M.abscessus_ATCC_1997 VERYTKLLAPDWQPVGDPEILTYFGTLIAEYQQAREEIK----HSKNDTD
**** ***** ** : ** : **..::.: .: :
Mb0666c|M.bovis_AF2122/97 V------------------
Rv0647c|M.tuberculosis_H37Rv V------------------
MAV_4514|M.avium_104 V------------------
MMAR_0982|M.marinum_M A------------------
MUL_0734|M.ulcerans_Agy99 A------------------
MLBr_01898|M.leprae_Br4923 I------------------
Mflv_5111|M.gilvum_PYR-GCK -------------------
Mvan_1241|M.vanbaalenii_PYR-1 -------------------
MSMEG_1353|M.smegmatis_MC2_155 IPDIPETGTETQAPSGDKA
TH_3124|M.thermoresistible__bu V------------------
MAB_2391|M.abscessus_ATCC_1997 GLGE---------------