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RAEIGPDFRPHYTFGDAYPASERAHVNWELSAPVWHTAQMGSTTHREVAKLDRVPLPVEAARVAATGWQV TRTAVRFIGRLPRKGPWQQKVIKELPQTFADLGPTYVKFGQIIASSPGAFGESLSREFRGLLDRVPPAKT DEVHKLFVEELGDEPARLFASFEEEPFASASIAQVHYATLRSGEEVVVKIQRPGIRRRVAADLQILKRFA QTVELAKLGRRLSAQDVVADFADNLAEELDFRLEAQSMEAWVSHLHASPLGKNIRVPQVHWDFTTERVLT MERVHGIRIDNAAAIRKAGFDGVELVKALLFSVFEGGLRHGLFHGDLHAGNLYVDEAGRIVFFDFGIMGR IDPRTRWLLRELVYALLVKKDHAAAGKIVVLMGAVGTMKPETQAAKDLERFATPLTMQSLGDMSYADIGR QLSALADAYDVKLPRELVLIGKQFLYVERYMKLLAPRWQMMSDPQLTGYFANFMVEVSREHQSDIEV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0647c | - | - | 100% (488) | hypothetical protein Rv0647c |
| M. tuberculosis H37Rv | Rv3197 | - | 8e-28 | 28.65% (370) | ABC transporter ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0666c | - | 0.0 | 99.80% (488) | hypothetical protein Mb0666c |
| M. gilvum PYR-GCK | Mflv_5111 | - | 0.0 | 83.14% (439) | hypothetical protein Mflv_5111 |
| M. leprae Br4923 | MLBr_01898 | - | 0.0 | 85.27% (448) | hypothetical protein MLBr_01898 |
| M. abscessus ATCC 19977 | MAB_3879 | - | 0.0 | 73.32% (446) | hypothetical protein MAB_3879 |
| M. marinum M | MMAR_0982 | - | 0.0 | 91.52% (448) | hypothetical protein MMAR_0982 |
| M. avium 104 | MAV_4514 | - | 0.0 | 91.34% (439) | ABC1 family protein |
| M. smegmatis MC2 155 | MSMEG_1353 | - | 0.0 | 84.09% (440) | ABC1 family protein |
| M. thermoresistible (build 8) | TH_3124 | - | 0.0 | 82.66% (444) | PUTATIVE ABC-1 domain protein |
| M. ulcerans Agy99 | MUL_0734 | - | 0.0 | 90.39% (458) | hypothetical protein MUL_0734 |
| M. vanbaalenii PYR-1 | Mvan_1241 | - | 0.0 | 84.04% (445) | hypothetical protein Mvan_1241 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5111|M.gilvum_PYR-GCK ----------------------------------------MSSTQRNQRT
Mvan_1241|M.vanbaalenii_PYR-1 ----------------------------------------MTAP-RN--T
MSMEG_1353|M.smegmatis_MC2_155 ----------------------------------------MSTTPAK--T
TH_3124|M.thermoresistible__bu ----------------------------------------MSTT------
Rv0647c|M.tuberculosis_H37Rv MRAEIGPDFRPHYTFGDAYPASERAHVNWELSAPVWHTAQMGST------
Mb0666c|M.bovis_AF2122/97 MRAEIGPDFRPHYTFGDAYPASERAHVNWELSAPVWHTAQMGST------
MAV_4514|M.avium_104 --------------------------------------------------
MMAR_0982|M.marinum_M ----------------------------------------MTTT------
MUL_0734|M.ulcerans_Agy99 ------------------------------MTLSIWHTAQMTTT------
MLBr_01898|M.leprae_Br4923 ----------------------------------------MSST------
MAB_3879|M.abscessus_ATCC_1997 --------------------------MTAQERSGRSAGEGRGAAGPAASS
Mflv_5111|M.gilvum_PYR-GCK PHRAVARLDRVPLPMEAARIGVTGWQITRTGGRVLSSLTTRG---TLQQK
Mvan_1241|M.vanbaalenii_PYR-1 PHRDVARLDRVPIPAEAARIGATGWQITRTGARVVTKLAGRG---SLQQK
MSMEG_1353|M.smegmatis_MC2_155 KHREVARLDRVPLPAEAARIGATGWQITRTGARVAANIFGRG---SLQQK
TH_3124|M.thermoresistible__bu KHREVAKLDRVSLPVEAARIGATGWQIARTGARVVTRLPSRG---SLQQK
Rv0647c|M.tuberculosis_H37Rv THREVAKLDRVPLPVEAARVAATGWQVTRTAVRFIGRLPRKG---PWQQK
Mb0666c|M.bovis_AF2122/97 THREVAKLDRVPLPVEAARVAATGWQVTRTAVRFIGRLPRKG---PWQQK
MAV_4514|M.avium_104 ----MAKLDRVPLPVEAARVAATGWQVTRSAARVLTKLPAKG---PWQQK
MMAR_0982|M.marinum_M KHREVAKLDRVPLPVEAARVAVTGWQVTRTAARFVTKLPGKGFASSWQQK
MUL_0734|M.ulcerans_Agy99 KHREVAKLDRVPLPVEAARVAVTGWQVTRTAARFVTKLPGKGFASSWQQK
MLBr_01898|M.leprae_Br4923 NNHQVVKLDRVPLPVEAARIAATYWQITRAAARVATKLAGKG---PWQQK
MAB_3879|M.abscessus_ATCC_1997 RGRQVAPLGRVALLSEAARLGTTGWQVARTAGRVLGKLTKKG---SLEQK
:. *.**.: ****:..* **::*:. *. : :* . :**
Mflv_5111|M.gilvum_PYR-GCK VVKQIPQAFADLGPTYVKFGQIIASSPGAFGEPLSREFRGLLDRVPPADS
Mvan_1241|M.vanbaalenii_PYR-1 IVKEIPQAFADLGPTYVKFGQIIASSPGAFGEPLSREFRSLLDRVPPADT
MSMEG_1353|M.smegmatis_MC2_155 IVKQVPKTFSDLGPTYVKFGQIIASSPGAFGEPLSREFRGLLDRVPPANP
TH_3124|M.thermoresistible__bu VIKELPKTFSDLGPTYVKFGQIIASSPGAFGEPLSREFRSLLDRVPPADP
Rv0647c|M.tuberculosis_H37Rv VIKELPQTFADLGPTYVKFGQIIASSPGAFGESLSREFRGLLDRVPPAKT
Mb0666c|M.bovis_AF2122/97 VIKELPQTFADLGPTYVKFGQIIASSPGAFGESLSREFRGLLDRVPPAKT
MAV_4514|M.avium_104 VIKQLPQTFADLGPTYVKFGQIIASSPGAFGESLSREFRGLLDRVPPADP
MMAR_0982|M.marinum_M IIKEIPQTFADLGPTYVKFGQIIASSPGAFGESLSREFRGLLDRVPPADT
MUL_0734|M.ulcerans_Agy99 IIKEIPQTFVDLGPTYVKFGQIIASSPGAFGESLSREFRGLLDRVPPADT
MLBr_01898|M.leprae_Br4923 VIREIPQTFANLGPTYVKFGQIIASSPSAFGESLAREFRGLLDQVPPADT
MAB_3879|M.abscessus_ATCC_1997 FIAELPQTFSDLGPTYVKLGQIIASSPGAFGEPLSREFRGLLDRVPPADP
.: ::*::* :*******:********.****.*:****.***:****..
Mflv_5111|M.gilvum_PYR-GCK DAVHKLLREDLGDEPQNLFKSFDEKPFASASIAQVHYATLHSGEEVVVKI
Mvan_1241|M.vanbaalenii_PYR-1 TAVHKLFREELGDEPQNLFKSFDDKPFASASIAQVHYATLHSGEEVVVKI
MSMEG_1353|M.smegmatis_MC2_155 DEVQKLIREELGDDPHKLFKTFDDTPFASASIAQVHYATLHSGEEVVVKI
TH_3124|M.thermoresistible__bu TAVRKLVRQELGADPSELFKHFDDKPFASASIAQVHYATLHSGEEVVVKI
Rv0647c|M.tuberculosis_H37Rv DEVHKLFVEELGDEPARLFASFEEEPFASASIAQVHYATLRSGEEVVVKI
Mb0666c|M.bovis_AF2122/97 DEVHKLFVEELGDEPARLFASFEEEPFASASIAQVHYATLRSGEEVVVKI
MAV_4514|M.avium_104 DEVHKLFLEELGADPSELFASWDETPFASASIAQVHYATLHTGEEVVVKI
MMAR_0982|M.marinum_M DQVHKLFVEELGAEPAELFAAFEEEPFASASIAQVHYATLKTGEEVVVKI
MUL_0734|M.ulcerans_Agy99 DQVHKLFVEELGTEPAELFATFEEEPFASASIAQVHYATLKTGEEVVVKI
MLBr_01898|M.leprae_Br4923 NEVHKLFVEELGDAPSKLFASFSEEPFASASIAQVHSAILHSGEHVVVKI
MAB_3879|M.abscessus_ATCC_1997 AAVRELIIAELGSEPEKLFASFDTEPFASASIAQVHYATLHSGEEVVVKI
*::*. :** * .** :. *********** * *::**.*****
Mflv_5111|M.gilvum_PYR-GCK QRPGIRRRVAADLQILKRGARLVEFAKLGQRLSAQDVVADFADNLAEELD
Mvan_1241|M.vanbaalenii_PYR-1 QRPGIRRRVAADLQILKRGARLVEFAKLGQRLSAQDVVADFADNLAEELD
MSMEG_1353|M.smegmatis_MC2_155 QRPGIRRRVAADLQILKRGARLVEFAKLGQRLSAQDVVADFADNLAEELD
TH_3124|M.thermoresistible__bu QRPGIRRRVTADLQILKHGARLVELAKLGRRLSAQDVVADFADNLAEELD
Rv0647c|M.tuberculosis_H37Rv QRPGIRRRVAADLQILKRFAQTVELAKLGRRLSAQDVVADFADNLAEELD
Mb0666c|M.bovis_AF2122/97 QRPGIRRRVAADLQILKRFAQTVELAKLGRRLSAQDVVADFADNLAEELD
MAV_4514|M.avium_104 QRPGIRRRVAADLQILKRFAQAVELAKLGRRLSAQDVVADFSDNLAEELN
MMAR_0982|M.marinum_M QRPGIRRRVAADLQILQRFAQAVELAKLGRRLSAQDVVADFSDNLAEELD
MUL_0734|M.ulcerans_Agy99 QRPGIRRRVAADLQILQRFAQAVELAKLGRRLSAQDVVADFSDNLAVELD
MLBr_01898|M.leprae_Br4923 QRPGIRRRVAADLQILKRFAQAVELAKLGRRLSAQDVVADFSDNLAEELN
MAB_3879|M.abscessus_ATCC_1997 QRPGIRKRVAADLQIMKRGAALLELGKVGRMLSARDVVDDFSGNLSEELD
******:**:*****::: * :*:.*:*: ***:*** **:.**: **:
Mflv_5111|M.gilvum_PYR-GCK FRLEAQSMDAWVAHMHSSPLGQNIRVPQVYWDLTSERVLTMERITGVRID
Mvan_1241|M.vanbaalenii_PYR-1 FRLEAQSMDAWVAHMHASPLGRNIRVPQVYWDLTSERVLTMERVTGVRID
MSMEG_1353|M.smegmatis_MC2_155 FRLEAQSMDAWVAHMHASPLGANIRVPTVYWDLTSERVLTMERITGVRID
TH_3124|M.thermoresistible__bu FRLEAQSMDTWVAHMHASPLGKNIRVPQVYWDLTSERVLTMERVSGVRID
Rv0647c|M.tuberculosis_H37Rv FRLEAQSMEAWVSHLHASPLGKNIRVPQVHWDFTTERVLTMERVHGIRID
Mb0666c|M.bovis_AF2122/97 FRLEAQSMEAWVSHLHASPLGKNIRVPQVHWDFTTERVLTMERVHGIRID
MAV_4514|M.avium_104 FRLEAQSMEAWVSHLHASPLGKNIRVPQVYWDFTTDRVLTMERVSGIRID
MMAR_0982|M.marinum_M FRLEAQSMDAWVAHLHASPLGRNIRVPQVHWNFTSERVLTMERVHGVRID
MUL_0734|M.ulcerans_Agy99 FRLEAQSMDAWVAHLHASPLGRNIRVPQVHWNFTSERVLTMERVHGVRID
MLBr_01898|M.leprae_Br4923 FRLEAQSMEAWGSYLHTSPLGKNIRVPKVHWEFTGERVLTMEQVHGIRID
MAB_3879|M.abscessus_ATCC_1997 FLAEGQAMQTWVEHLHTSSLGKNIRVPDVHWHYTTSKVLTMERVHGIRID
* *.*:*::* ::*:*.** ***** *:*. * .:*****:: *:***
Mflv_5111|M.gilvum_PYR-GCK DVAAIRKKGFDGEALVKALLFSVFEGGLRHGLFHGDLHAGNLYVDDDGKV
Mvan_1241|M.vanbaalenii_PYR-1 DVAAIRKKGFDGTELVKALLFSVFEGGLRHGLFHGDLHAGNLYVDDDGKI
MSMEG_1353|M.smegmatis_MC2_155 DVAAIRKKGFDGTELVKALLFSVFEGGLRHGLFHGDLHAGNLYVDDDGKI
TH_3124|M.thermoresistible__bu DVAALRKKGFEGTELVKALLFSLFEGGLRHGLFHGDLHAGNLYVDDDGKI
Rv0647c|M.tuberculosis_H37Rv NAAAIRKAGFDGVELVKALLFSVFEGGLRHGLFHGDLHAGNLYVDEAGRI
Mb0666c|M.bovis_AF2122/97 NTAAIRKAGFDGVELVKALLFSVFEGGLRHGLFHGDLHAGNLYVDEAGRI
MAV_4514|M.avium_104 DVAAVRKAGFDGVELVKALLFSLFEGGLRHGLFHGDLHAGNLYVDEAGRI
MMAR_0982|M.marinum_M NVAAIRKAGFDGTELVKALLFSVFEGGLRHGLFHGDLHAGNLYVDEEGRI
MUL_0734|M.ulcerans_Agy99 NVAAIRKAGFDGTELVKALLFSVFEGGLRHGLFHGDLHAGNLYVDEEGRI
MLBr_01898|M.leprae_Br4923 NADAIRKSGFDGVELVKALLFSVFEGGLRHGLFHGDLHAGNLHVDDQGRI
MAB_3879|M.abscessus_ATCC_1997 DAPAIRKAGFDGTELVKSLLFSVFESGLRQGLFHGDLHAGNLLVDDEGRI
:. *:** **:* ***:****:**.***:************ **: *::
Mflv_5111|M.gilvum_PYR-GCK VFFDFGIMGRIDPRTRWLLRELVYALLVKKDHAAAGKIVVLMGAVGTMRP
Mvan_1241|M.vanbaalenii_PYR-1 VFFDFGIMGRIDPRTRWLLRELVYALLVKKDHAAAGKIVVLMGAVGTMKP
MSMEG_1353|M.smegmatis_MC2_155 VFFDFGIMGRIDPRTRWLLRELVHALLVKKDHAAAGKIVVLMGAVGTVKP
TH_3124|M.thermoresistible__bu VFFDFGIMGRIDPRTRWLLRELVYALLVKKDHAAAGKIVVLMGAVGTTKP
Rv0647c|M.tuberculosis_H37Rv VFFDFGIMGRIDPRTRWLLRELVYALLVKKDHAAAGKIVVLMGAVGTMKP
Mb0666c|M.bovis_AF2122/97 VFFDFGIMGRIDPRTRWLLRELVYALLVKKDHAAAGKIVVLMGAVGTMKP
MAV_4514|M.avium_104 VFFDFGIMGRIDPRTRWLLRELVYALLVKKDHAAAGKIVVLMGAVGTVKP
MMAR_0982|M.marinum_M VFFDFGIMGRIDPRTRWLLRELVYALLVKKDHAAAGKIVVLMGAVGTMKP
MUL_0734|M.ulcerans_Agy99 VFFDFGIMGRIDPRTRWLLRELVYALLVKKDHAAAGKIVVLMGAVGTMKP
MLBr_01898|M.leprae_Br4923 VFFDFGIMGRIDPRTRWLLRELVFALLVKKDHAAAGKIVVLMGAVGTVKP
MAB_3879|M.abscessus_ATCC_1997 VFLDFGIVGFIDPRTRWLLRELIHALLVKKDHRAAGKIVVMLGAVGNPGD
**:****:* ************:.******** *******::****.
Mflv_5111|M.gilvum_PYR-GCK EAEAARDLEKFATPLTLKSLGDLSYAEIGKQLSTLADAYDVKLPRELVLI
Mvan_1241|M.vanbaalenii_PYR-1 EAEAAKDLEKFATPLTLKSLGDLSYAEIGKQLSALADAYDVKLPRELVLI
MSMEG_1353|M.smegmatis_MC2_155 EGQAAKDLEAFATPLTMKSLGDMSYAEIGRQLSALADAYDVKLPRELVLI
TH_3124|M.thermoresistible__bu EAQAAKDLEKFATPLTMSTLGDMSYAEIGRQLSALAEAYDVKLPRELVLI
Rv0647c|M.tuberculosis_H37Rv ETQAAKDLERFATPLTMQSLGDMSYADIGRQLSALADAYDVKLPRELVLI
Mb0666c|M.bovis_AF2122/97 ETQAAKDLERFATPLTMQSLGDMSYADIGRQLSALADAYDVKLPRELVLI
MAV_4514|M.avium_104 EAQAAKDLEKFATPLTMQTLGDMSYADIGRQLSALADAYDVKLPRELVLI
MMAR_0982|M.marinum_M EAQAAKDLEKFATPLTMQSLGDMSYADIGRQLSALADAYDVKLPRELVLI
MUL_0734|M.ulcerans_Agy99 EAQAAKDLEKFATPLTMQSLGDMSYADIGRQLSALADAYDVKLPRELVLI
MLBr_01898|M.leprae_Br4923 EARAAKDLENFTTPLAMKTLGDMSYTDIGRQLSALSDAYNVKLPRELVLI
MAB_3879|M.abscessus_ATCC_1997 AEQGTQDIQAFATPLTMKSLGDMSYSEIGKQLSTLAEQYDVKLPRELVLI
..::*:: *:***::.:***:**::**:***:*:: *:**********
Mflv_5111|M.gilvum_PYR-GCK GKQFLYVERYMKLLAPKWQMMSDPALTGYFANFMVEVSREHS-------D
Mvan_1241|M.vanbaalenii_PYR-1 GKQFLYVERYMKLLAPKWQMMSDPALTGYFANFMVEVSREHS-------D
MSMEG_1353|M.smegmatis_MC2_155 GKQFLYVERYMKLLAPKWQMMSDPQLTGYFANFMVEVSREHK-------E
TH_3124|M.thermoresistible__bu GKQFLYVERYMKLLAPKWQMMSDPELTGYFANFMVDIKREHD-------A
Rv0647c|M.tuberculosis_H37Rv GKQFLYVERYMKLLAPRWQMMSDPQLTGYFANFMVEVSREH---------
Mb0666c|M.bovis_AF2122/97 GKQFLYVERYMKLLAPRWQMMSDPQLTGYFANFMVEVSREH---------
MAV_4514|M.avium_104 GKQFLYVERYMKLLAPKWQMMSDPQLTGYFANFMVEVSREHSSEF-----
MMAR_0982|M.marinum_M GKQFLYVERYMKLLAPKWQMMSDPQLTGYFANFMVEVSREHQGDSSDASG
MUL_0734|M.ulcerans_Agy99 GKQFLYVERYMKLLAPKWQMMSDPQLTGYFANFMVEVSREHQGDSSDASG
MLBr_01898|M.leprae_Br4923 GKQFLYVERYMKLLAPEWQIMLDPELTGYFANFMVEVSREH---------
MAB_3879|M.abscessus_ATCC_1997 GKQFLYVERYMKLLAPRWQMMDDPELKGYFGNFIVDISREHN--------
****************.**:* ** *.***.**:*::.***
Mflv_5111|M.gilvum_PYR-GCK TGPDA--------------------
Mvan_1241|M.vanbaalenii_PYR-1 DVEA---------------------
MSMEG_1353|M.smegmatis_MC2_155 IDDVDEIPDIPETGTETQAPSGDKA
TH_3124|M.thermoresistible__bu KADELEV------------------
Rv0647c|M.tuberculosis_H37Rv -QSDIEV------------------
Mb0666c|M.bovis_AF2122/97 -QSDIEV------------------
MAV_4514|M.avium_104 -ESDVEV------------------
MMAR_0982|M.marinum_M DASDVEA------------------
MUL_0734|M.ulcerans_Agy99 DASDVEA------------------
MLBr_01898|M.leprae_Br4923 -QSDVEI------------------
MAB_3879|M.abscessus_ATCC_1997 REGDI--------------------