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TDETGASSDHSDDVAQVVSRLIRFDTTNSGEPGTTKGEAECARWVAEQLAEVGYQPEYVESGAPGRGNVF ARLAGADSSRGALLIHGHLDVVPAEPAEWSVHPFSGAIEDGYVWGRGAVDMKDMVGMMIVVARHLRQAAI VPPRDLVFAFVADEEHGGKYGSHWLVDNRPDLFDGITEAIGEVGGFSLTVPRHDGGERRLYLIETAEKGI QWMRLTARGRAGHGSMVHDQNAVTAVCEAVARLGRHQFPLVCTDTVAQFLAVVGEETGLAFDLDSPDLAG TIDKLGPMARMLKAVLHDTANPTMLKAGYKANVVPATAEAVVDCRVLPGRRAAFEAEVDALIGPDVTREW VSDLPSYETTFDGDLVAAMNAAVLAVDPDGRTVPYMLSGGTDAKAFARLGIRCFGFSPLRLPPDLDFTSL FHGVDERVPIDGLRFGTEVLTHLLTHC*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2141c | - | - | 100% (448) | hypothetical protein Rv2141c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2165c | - | 0.0 | 100.00% (448) | hypothetical protein Mb2165c |
| M. gilvum PYR-GCK | Mflv_3037 | - | 0.0 | 74.44% (450) | hypothetical protein Mflv_3037 |
| M. leprae Br4923 | MLBr_01288 | - | 0.0 | 84.15% (448) | hypothetical protein MLBr_01288 |
| M. abscessus ATCC 19977 | MAB_2102 | - | 0.0 | 76.19% (441) | hypothetical protein MAB_2102 |
| M. marinum M | MMAR_3123 | - | 0.0 | 87.87% (445) | hypothetical protein MMAR_3123 |
| M. avium 104 | MAV_2350 | - | 0.0 | 84.04% (451) | hypothetical protein MAV_2350 |
| M. smegmatis MC2 155 | MSMEG_4200 | - | 0.0 | 76.64% (441) | hypothetical protein MSMEG_4200 |
| M. thermoresistible (build 8) | TH_2370 | dapE2 | 0.0 | 76.89% (437) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2373 | - | 0.0 | 88.09% (445) | hypothetical protein MUL_2373 |
| M. vanbaalenii PYR-1 | Mvan_3489 | - | 0.0 | 77.16% (429) | hypothetical protein Mvan_3489 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2141c|M.tuberculosis_H37Rv ----------------MTD---ETGASSDHSDDVAQVVSRLIRFDTTNSG
Mb2165c|M.bovis_AF2122/97 ----------------MTD---ETGASSDHSDDVAQVVSRLIRFDTTNSG
MMAR_3123|M.marinum_M ----------------MTQKNGETGTSTDSRDDVAEVVSRLIRFDTTNTG
MUL_2373|M.ulcerans_Agy99 ----------------MTQKNGETGTSTDSRDDVAEVVSRLIRFDTTNTG
MLBr_01288|M.leprae_Br4923 MQKTKVLRSLVVAVVGKVTVTVETDVLVNPSDDVVEVVSRLIRFDTTNTG
MAV_2350|M.avium_104 ----------------MTIQSGASEVTANPSDDVVEVVSTLIRFDTTNTG
Mflv_3037|M.gilvum_PYR-GCK ----------------MTGDAGGRSGGLTPSDEVVDLVSTLIRFDTSNTG
Mvan_3489|M.vanbaalenii_PYR-1 -------------------------------------MSTLIRFDTSNTG
MAB_2102|M.abscessus_ATCC_1997 ----------------MT------SVNPAPEDEVVDLVSTLIRFDTSNTG
MSMEG_4200|M.smegmatis_MC2_155 -----------------------MTVSAASADEVVDLVSALIRFDTSNTG
TH_2370|M.thermoresistible__bu -----------------------VTNPPQPADEVVDLVSTLIRFDTSNTG
:* ******:*:*
Rv2141c|M.tuberculosis_H37Rv EPGTTKGEAECARWVAEQLAEVGYQPEYVESGAPGRGNVFARLAGADSSR
Mb2165c|M.bovis_AF2122/97 EPGTTKGEAECARWVAEQLAEVGYQPEYVESGAPGRGNVFARLAGADSSR
MMAR_3123|M.marinum_M EPETTKGEAECARWVAEQLAEVGYQTEYVESGAPGRGNVFARLRGADSSR
MUL_2373|M.ulcerans_Agy99 EPETTKGEAECARWVAEQLAEVGYQTEYVESGAPGRGNVFARLRGADSSR
MLBr_01288|M.leprae_Br4923 DPETTRGEAECAQWVASQLAEVGYQPEYLESGAPGRGNVFARLAGEDSSR
MAV_2350|M.avium_104 EPETTKGEAECAQWVAEQLAAVGYAPHYVESGAPGRGNVFVRLPGADSSR
Mflv_3037|M.gilvum_PYR-GCK DPATTMGEAACARWVADQLAEVGYVCEYIEAGAPGRANVFARLEGADRSR
Mvan_3489|M.vanbaalenii_PYR-1 DPATTKGEADCARWVADQLAEVGYVTEYVEAGAPGRANVFARLEGADRSR
MAB_2102|M.abscessus_ATCC_1997 ELETTKGEAECARWIQQQLEEVGYTCEYVEAGAPGRGNLFARLPGASSDR
MSMEG_4200|M.smegmatis_MC2_155 DPATTKGEAECAHWVAQQLEEVGYETEYVESGAPGRGNVFARLRGADPSR
TH_2370|M.thermoresistible__bu DPATTRVEAEAAHWVADRLREVGYQTEYVEAGAPGRGNVFARLPGADPSR
: ** ** .*:*: .:* *** .*:*:*****.*:*.** * . .*
Rv2141c|M.tuberculosis_H37Rv GALLIHGHLDVVPAEPAEWSVHPFSGAIEDGYVWGRGAVDMKDMVGMMIV
Mb2165c|M.bovis_AF2122/97 GALLIHGHLDVVPAEPAEWSVHPFSGAIEDGYVWGRGAVDMKDMVGMMIV
MMAR_3123|M.marinum_M GALLIHGHLDVVPAEAADWSVHPFSGAIEDGYVWGRGAVDMKDMVGMMIV
MUL_2373|M.ulcerans_Agy99 GALLIHGHLDVVPAEAADWSVHPFSGAIEDGYVWGRGAVDMKDMVGMMIV
MLBr_01288|M.leprae_Br4923 GALLIHGHLDVVPAETAEWSVHPFSGAVEGGQVWGRGAIDMKDMVGMMIV
MAV_2350|M.avium_104 GALLIHGHLDVVPAEPTEWSVHPFSGAVKDGFVWGRGAVDMKDMVGMMIV
Mflv_3037|M.gilvum_PYR-GCK GALMLHGHLDVVPAEASDWSVHPFSGAVEDGYVWGRGAVDMKDMVGMILA
Mvan_3489|M.vanbaalenii_PYR-1 GALMLHGHLDVVPAEASDWSVHPFSGAVEDGYVWGRGAVDMKDMVGMIIA
MAB_2102|M.abscessus_ATCC_1997 GALLIHGHLDVVPAEAPDWSVHPFSGAVNDGYVWGRGAVDMKDMVGMMIA
MSMEG_4200|M.smegmatis_MC2_155 GALMVHGHLDVVPAEPADWSVHPFSGAVKDGYVWGRGAVDMKDMVGMTLA
TH_2370|M.thermoresistible__bu GALLVHGHLDVVPAEPADWSVHPFSGAVEDGYVWGRGAVDMKNMLGMMLA
***::**********..:*********::.* ******:***:*:** :.
Rv2141c|M.tuberculosis_H37Rv VARHLRQAAIVPPRDLVFAFVADEEHGGKYGSHWLVDNRPDLFDGITEAI
Mb2165c|M.bovis_AF2122/97 VARHLRQAAIVPPRDLVFAFVADEEHGGKYGSHWLVDNRPDLFDGITEAI
MMAR_3123|M.marinum_M VARHFRRAGIVPPRDLVFAFLADEEHGGHFGAHWLVDNRPDLFDGVTEAV
MUL_2373|M.ulcerans_Agy99 VARHFRRAGIVPPRDLVFAFLADEEHGGHFGAHWLVDNRPDLFDGVTEAV
MLBr_01288|M.leprae_Br4923 VARQLKQAGIAPPRDLVFAFVADEEHGGSYGSQWLVDNRPDLFDGVTEAI
MAV_2350|M.avium_104 VARHLKRAGIVPPRDLVFAFIADEEHGGTFGAQWLVDNRPELFAGVTEAI
Mflv_3037|M.gilvum_PYR-GCK VARHFKRSGIVPPRDLVFAFVSDEEAGGNYGCKWLVEHRPDLFEGVTEAV
Mvan_3489|M.vanbaalenii_PYR-1 VARHFKRSGIVPPRDLVFAFVSDEEAGGNFGCKWLVENRPDLFDGVTEAV
MAB_2102|M.abscessus_ATCC_1997 IARYFKRSGIVPPRDLVWAFVSDEENGGKWGSQWLVDNRPDLFEGITEAI
MSMEG_4200|M.smegmatis_MC2_155 VARHFKRAGIVPPRDLVFAFVADEEHGGTYGADWLVNNRPDLFEGVTEAI
TH_2370|M.thermoresistible__bu VARHFKRAGIVPPRDIVFAFLSDEEHGGTYGAQWLVDHRPDLFTGVTEAI
:** ::::.*.****:*:**::*** ** :*..***::**:** *:***:
Rv2141c|M.tuberculosis_H37Rv GEVGGFSLTVPRHDGGERRLYLIETAEKGIQWMRLTARGRAGHGSMVHDQ
Mb2165c|M.bovis_AF2122/97 GEVGGFSLTVPRHDGGERRLYLIETAEKGIQWMRLTARGRAGHGSMVHDQ
MMAR_3123|M.marinum_M GEVGGFSLTVPRRDGGERRLYLVETAEKGILWMRLTAQGRAGHGSMVHDH
MUL_2373|M.ulcerans_Agy99 GEVGGFSLTVPRRDGGERRLYLVETAEKGILWMRLTAQGRAGHGSMVHDH
MLBr_01288|M.leprae_Br4923 GEVGGFSLTVPCRNGGERRLYLIETAEKGMQWMRLTARGRAGHGSMVHNQ
MAV_2350|M.avium_104 GEVGGFSLTVPRRDGGERRLYLIETAEKGLSWMKLTARGPAGHGSMVHDQ
Mflv_3037|M.gilvum_PYR-GCK GEVGGFSLTVPRPDGGEKRLYLVETAEKAMLWMRLTARARAGHGSMVHDD
Mvan_3489|M.vanbaalenii_PYR-1 GEVGGFSLTVPRRDGGERRLYLVETAEKAMLWMRLTARGRAGHGSMVHDD
MAB_2102|M.abscessus_ATCC_1997 GEVGGFSLTVPRRQGGERRLYLLETAEKGIAWMRLTAKARAGHGSMVHED
MSMEG_4200|M.smegmatis_MC2_155 GEVGGFSLTVPRKDGGERRLYLIETAEKGLSWMRLTARGRAGHGSMVHDD
TH_2370|M.thermoresistible__bu GEVGGFSLTVPRKDGGERRLYLVETAEKGLAWMRLTARGRAGHGSMVNDD
*********** :***:****:*****.: **:***:. *******::.
Rv2141c|M.tuberculosis_H37Rv NAVTAVCEAVARLGRHQFPLVCTDTVAQFLAVVGEETGLAFDLDSPDLAG
Mb2165c|M.bovis_AF2122/97 NAVTAVCEAVARLGRHQFPLVCTDTVAQFLAVVGEETGLAFDLDSPDLAG
MMAR_3123|M.marinum_M NAVTTVAEAVARLGRHQFPLVITDTVAQFLHAVSEETGLELDPGSPDLEG
MUL_2373|M.ulcerans_Agy99 NAVTTVAEAVARLGRHQFPLVITDTVAQFLHAVSEETGLDLDPDSPDLEG
MLBr_01288|M.leprae_Br4923 NAVTAVAEAVARLGRHQFPLVTTDTVVQFLAAISEETGLEFDIGSPDLEG
MAV_2350|M.avium_104 NAVTAVAEAVARLGRHQFPLVLTDTVNQFLAAVSEETGLTFDTQSGDLRG
Mflv_3037|M.gilvum_PYR-GCK NAVTAVAEAVAKLGRHRFPIVLTESVEQFLTAVGEETGYAFDPASPDIEG
Mvan_3489|M.vanbaalenii_PYR-1 NAVTAVAEAVAKLGRHRFPIVLTESVEQFLTAVGEETGYAFDPASPDIEG
MAB_2102|M.abscessus_ATCC_1997 NAVTAVAEAVAKLGRHRFPLVLTEAVTQFLGAVAEETGYDFDPDSPDLEG
MSMEG_4200|M.smegmatis_MC2_155 NAVTAIAGAVDRLGRHEFPLVLSPAVEEFLTAVAEETGYTFDPNSPDLEG
TH_2370|M.thermoresistible__bu NAVTAVAEAVARLGRHRFPLVLTESVQQFLEAVAEETGYSFDVNSPDLEG
****::. ** :****.**:* : :* :** .:.**** :* * *: *
Rv2141c|M.tuberculosis_H37Rv TIDKLGPMARMLKAVLHDTANPTMLKAGYKANVVPATAEAVVDCRVLPGR
Mb2165c|M.bovis_AF2122/97 TIDKLGPMARMLKAVLHDTANPTMLKAGYKANVVPATAEAVVDCRVLPGR
MMAR_3123|M.marinum_M TLDKLGPIARMLKAVLRDTANPTMLKAGYKANVIPATAEAVVDCRVLPGR
MUL_2373|M.ulcerans_Agy99 TLDKLGPIARMLKAVLRDTANPTMLKAGYKANVIPATAEAVVDCRVLPGR
MLBr_01288|M.leprae_Br4923 AIEKLGPMARMLKAVLYDTANPTVLKAGYKVNVVPATAEAMVDCRILPGR
MAV_2350|M.avium_104 VVEKLGPMARMLKAVLHDTANPTMLKAGYKANVVPAIAEAVVDCRILPGR
Mflv_3037|M.gilvum_PYR-GCK TVAKLGGIARIVGATLRDTANPTMLKAGYKANVIPATAEAVIDCRVLPGR
Mvan_3489|M.vanbaalenii_PYR-1 TVAKLGGIARIVGATLRDTANPTMLNAGYKANVIPATAEAVIDCRVLPGR
MAB_2102|M.abscessus_ATCC_1997 TVAKLGSIGKIVGATLRDTANPTMLKAGYKANVIPATAEAVIDCRVLPGR
MSMEG_4200|M.smegmatis_MC2_155 TIAKLGGVARIVSATLRDTANPTMLKAGYKANVIPAVAEAMIDCRVLPGR
TH_2370|M.thermoresistible__bu TIAKLGGVARIVGATLRDTANPTMLTAGYKANVIPQTAEAIVDCRVLPGR
.: *** :.::: *.* ******:*.****.**:* ***::***:****
Rv2141c|M.tuberculosis_H37Rv RAAFEAEVDALIGPDVTREWVSDLPSYETTFDGDLVAAMNAAVLAVDPDG
Mb2165c|M.bovis_AF2122/97 RAAFEAEVDALIGPDVTREWVSDLPSYETTFDGDLVAAMNAAVLAVDPDG
MMAR_3123|M.marinum_M QAAFEAEVDELIGPDVSREWISELASYETSFDGDLVDAMNAAVLSVDPDG
MUL_2373|M.ulcerans_Agy99 QAAFEAEVDELIGPDVSREWISELASYETSFDGDLVDAMNAAVLSVDPDG
MLBr_01288|M.leprae_Br4923 QAAFEAAIDELIGPDVTREWIKDLPPYETAFDGDLVDAMNAAVLAVDPDG
MAV_2350|M.avium_104 KAAFEAEIDELIGPDVTREWIKDFSSYETGFDGDLVDAMNDAVLALDPDA
Mflv_3037|M.gilvum_PYR-GCK LADFEREVDELIGPDVKREWITNLPSYETPFDGELLDAMNTAILANDPDA
Mvan_3489|M.vanbaalenii_PYR-1 LADFEREVDELIGPDVKREWITNLPSYETPFDGELLEAMNNAILAADPDA
MAB_2102|M.abscessus_ATCC_1997 LEAFEREVDEIIGPDVEREWVQLLPAYETTFDGDLVDAMNAAVLEFDPEA
MSMEG_4200|M.smegmatis_MC2_155 KEAFEREVDELIGPDVTRSWERDLPSYETSFDGDLVDAMNASVLTLDPEA
TH_2370|M.thermoresistible__bu RAAFEREVDELIGPDVERSWERDLPAVETTFDGELVDAMNASLLAVDPEA
** :* :***** *.* :.. ** ***:*: *** ::* **:.
Rv2141c|M.tuberculosis_H37Rv RTVPYMLSGGTDAKAFARLGIRCFGFSPLRLPPDLDFTSLFHGVDERVPI
Mb2165c|M.bovis_AF2122/97 RTVPYMLSGGTDAKAFARLGIRCFGFSPLRLPPDLDFTSLFHGVDERVPI
MMAR_3123|M.marinum_M RTVPYMLSGGTDAKAFARLGIRCFGFSPLRLPPELDFAALFHGVDERVPI
MUL_2373|M.ulcerans_Agy99 RTVPYMLSGGTDAKAFARLGIRCFGFSPLRLPPELDFATLFHGVDERVPI
MLBr_01288|M.leprae_Br4923 RTVPYMASGGTDAKAFARLGIRCFGFTPLRLPPELDFTALFHGVDERVSI
MAV_2350|M.avium_104 RTVPYMLSGGTDAKSFARLGIRCFGFSPLRLPPDLDFTALFHGVDERVPI
Mflv_3037|M.gilvum_PYR-GCK RTVPYMLSGGTDAKHFARLGIRCFGFAPLRLPPDLDFAALFHGVDERVPV
Mvan_3489|M.vanbaalenii_PYR-1 RTVPYMMSGGTDAKHFARLGIRCFGFAPLRLPPDLDFAALFHGVDERVPV
MAB_2102|M.abscessus_ATCC_1997 RTVPYMLSGGTDAKAFARLGIRCFGFAPLKLPPELDFASLFHGVDERVPV
MSMEG_4200|M.smegmatis_MC2_155 RIVPYMLSAGTDAKSFQRLGIRCFGFAPLRLPPDLDFAALFHGVDERVPV
TH_2370|M.thermoresistible__bu RTVPYMMSGGTDAKAFQRLGIRCFGFVPLRLPPELDFSALFHGVDERVPV
* **** *.***** * ********* **:***:***::*********.:
Rv2141c|M.tuberculosis_H37Rv DGLRFGTEVLTHLLTHC
Mb2165c|M.bovis_AF2122/97 DGLRFGTEVLTHLLTHC
MMAR_3123|M.marinum_M DALRFGTEVLTHFLTHC
MUL_2373|M.ulcerans_Agy99 DALRFGTEVLTHFLTHC
MLBr_01288|M.leprae_Br4923 DALKFGIDVLAHFLTHC
MAV_2350|M.avium_104 DALRFGTDVLTHFLTHC
Mflv_3037|M.gilvum_PYR-GCK DALTFGAQVLEHFLLHS
Mvan_3489|M.vanbaalenii_PYR-1 DALTFGAQVLENFLLHS
MAB_2102|M.abscessus_ATCC_1997 DALTFGTKVLQHFLLNH
MSMEG_4200|M.smegmatis_MC2_155 DALQFGAGVLEHFLQNC
TH_2370|M.thermoresistible__bu DALEFGARVLDHFLQHC
*.* ** ** ::* :