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VTAVDYRPAPESGEEIILFRASFAQQRMWFLSRLEPGSHYYNVPIVLHFRGAVRRDALQRALAGMVSRHE ILRTTFVEVEGEVMQAVAADSAVPVPLTAIESSAAHSLPPIARPEVRTAVLELVCTPFDLSSGPLLRAHL LDVQDGEYLLVLTMHHIIVDGWSIGVICKELRELYASEVGGIPAALPSLELQIGDLAEQEHELMSAPTRE RHLAYWRSQLAGDLSAPALPFDRDRPSRNVFHGATVDFTLSPSDTAVIAAFGRDRDATIFATLLAAFYAL LYRYSGSDDQVVGAPMANREDHRVSALIGLFVNTVPLRARVDPNAGFAALVSHVREVTLGAYEHQELPLE QIIDEVAPTRLPGRNPMVAVLFAMQSPPPVDLDFAGTRASFVGVPTGTTRADVEMHFWPLGDRIGVQFVY STELFDAATVEQMRDDYTALLRAALASPHLPIGHLPLGAGEALVVQSLAPMFRHAENSVAIVDAGVEITH AHLRKTAAQLVAAMPGVRGGTVVLGFERGSDLVAAVVAAVSAGAGRLVWLPASLPAPYREHSLRQLAPTA VVDDATVADAAATGIRAMGESETLNTDAAVGLLDSSLAELLVALLYSGRIDLKNDAPASRAVLTADGRSA PPGVLGELCIGRPGEGVLPTGIQARMRRDSSVEIAHTVRGCVWDGNRWADLTTVEAVLIDHELVDDCAVL SRRINSGTAELVAYVATSAPASTRRLAEIARTVLPPLLVPRAFVPVAALPVTPAGALDSAALARLPVIDD ELVEQWSARLPEATMVRAVPDIDEAPSVLVGDPNPPAKQAPAAPGAQPGGQEPSVLHGGPAVIPVVASLP GALTRAAREAATTELVFLDESGTERTLNYAEVLDSAQRVLGGLRAVGMAPGDLAIVHLSRNDDFVAAIWG CFLGGIVPVPVAPNVVGGTEKVAAAWHTLKQPLIVGEIPQPVAHQGARVLLIGDLLTHEPDTDHHEPDPD EVALLLLTSGSTGQPKGVQLSHRNILSRSASTAQSNAFGPEDISFNWMPLEHVGGIVMSHLQDVYVHCRQ VHAATSWVLADPLRWLTIADRYGVTNTWAPNFAFGLIADRLAETPDAAQFDLTRLRFILNGGEAIVPRVA RRFLRMMEGFGLPRNAMRPSWGMSETSSGVVFSQNFSIETTADTDEFTDLGGPIPGTRLRVADMDGSVVP EGQIGRVQISGPTVTRGYYADPERTAEAFATDGWFDTGDLGRIRAGVLTLTGRAKDIIIVNGVNYSCHAI ESAVEESPLVISSYVAAIAVRLPGSDTDGLAIVFSAQAAVAEEDVLADVRARVLAVGPNPDLLIPVPPES IPKTDIGKIQRNLLRQQFAEGKFADIVRRVRTSGAPTDTIPNWFFRPLWHRRDRLRPSVPVDGAVLLLGD SGALGSLLADRLRAQGAHVVCAAVADVAERSDRPAGVGAVQTVVYLAAPQEDDAKAKNHPELLAGSLLDV ARIVRSVTNGRFNEPPPAVYVVGRGIERVANTDMADPELAPIPVLLRSAVAEMPGLRVRFIDLDPRDLAA GADDIVGELGYATNDIEVAYRDGVRWVKGLQRLPDDATLAAQIPSGAVHLISGGLGGLAYELARMLIERF DGRVLLVGHRDPDERQLAAYRRLCDIAGGASVRLEVADVCDTGRVWDAVTAAENAWGIQLAGIWHLAGIY REQSLAAMTDAEFADIARAKVGGARALHAIALHRPGIRFVSFSSVNGFFGGSTVGGYSVANAYLDAFALY QRRTCGIAAHSVAWTMWDRVGMSAQVEHVEGTRARGYRVVGRVAALNSLLVALAHDEPHVLVGLDDTKPA IRARLSGVAPAGQVLVADLAEAVPGFADMPLRDKYDAIVPTRVQSAGVARTFVAARDETERRVSGIWRRV LGSDHFGVTDSFFDIGGNSVLLALAQRLVQEEFGCQIALVDLFRYPTVSSLAVYLSSREFASDPSDPEPV AVADAGVGSGRARIRQEARRRRRAR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_2258 | - | - | 100% (1985) | peptide synthetase and polyketide synthase |
M. abscessus ATCC 19977 | MAB_4691c | - | 9e-56 | 29.77% (598) | non-ribosomal peptide synthetase PstA |
M. abscessus ATCC 19977 | MAB_4690c | - | 7e-51 | 27.63% (608) | non-ribosomal peptide synthetase PstA |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0104 | nrp | 2e-57 | 28.64% (611) | peptide synthetase |
M. gilvum PYR-GCK | Mflv_1935 | - | 5e-48 | 31.96% (510) | acyl-CoA synthetase |
M. tuberculosis H37Rv | Rv0101 | nrp | 2e-57 | 28.64% (611) | peptide synthetase |
M. leprae Br4923 | MLBr_00243 | - | 6e-45 | 28.88% (509) | long-chain-fatty-acid--CoA ligase |
M. marinum M | MMAR_3176 | - | 6e-61 | 27.93% (598) | non-ribosomal peptide synthetase |
M. avium 104 | MAV_3239 | - | 2e-59 | 30.94% (585) | syringomycin synthetase |
M. smegmatis MC2 155 | MSMEG_0019 | - | 4e-60 | 31.12% (588) | amino acid adenylation |
M. thermoresistible (build 8) | TH_4455 | - | 4e-66 | 32.92% (559) | PUTATIVE putative syringomycin synthetase |
M. ulcerans Agy99 | MUL_4648 | pks16 | 1e-49 | 31.79% (541) | acyl-CoA synthetase |
M. vanbaalenii PYR-1 | Mvan_1000 | - | 1e-65 | 29.79% (584) | amino acid adenylation domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M -------------------------------------------------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 MTADSLDIAELLELWNNHSTPERTSTVPTLFAAQCALTPDEVAVVDGERR MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M -------------------------------------------------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LTYRHLETHVAQLAHAVRVAAGEGPEPIVAIGVPRSAEMVVCVLAAMMAG MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M -------------------------------------------------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VAFVPLDPSWPAHRRRQVLADSGAVATFITREDESDWGVPGLRVDLGAWQ MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M -------------------------------------------------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 FTAESPVLPQADVHPAQLAYVIFTSGSTGKPKGAMIRHDAIAERLQWQRD MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M -------------------------------------------------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 HILHFGKHDHTDASLFKAPLSFDISVNEILLPLVSGGRVVVAVPDGEKDP MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M -------------------------------------------------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 EYLLELIRTEQVTFVYLVSSMLDTLLELDRLATADGAPSSLASLRHVWCG MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M -------------------------------------------------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 GEVLTPGLFARFRKQLTTTLYHGYGPAEATIGVSHVIYRDTAERIATSIG MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M -------------------------------------------------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 RPNPHTQLYVLDEYLRPVPPGVGGELYAAGFLLGRGYVNAPSLTASRFVA MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M -------------------------------------------------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 NPFDGNGSRMYRTGDLARWTEDGSLEFLGRADNQVKIGGRRVELEEIESQ MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 MLGVGRVGVEDSFFDLGGDSLSAMRLIAAVNGVLGAGVSVRTLFEAPTVA MMAR_3176|M.marinum_M -------------------------------------------------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LADHPAVRHAVVDVHRQGGADVLVGYLVAADGVRNDAAWHAEVADWARTR MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 QLAPRVRGGGRTLARVVAGERPAVVPLSFAQSRLWFLDQLQGPSPMYNMA MMAR_3176|M.marinum_M --------------------MLVDRVRASSAQEALWFAQKLVPDLPNNVS MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LPEYMVPKAFVALDQVPLTANGKTDRRALPAPDLERSGTVKPPRTPRETV MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 AALKLQGPLDVSVL----------------RAALADVIARHESLRTVFAV MMAR_3176|M.marinum_M ICFEVSGPIDHDMM----------------AVALRHHGREAHTLRVRFLE MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LCQVFADALDIDAVGVDEDFFALGGDSIVAIRVVSRLRAAGYTLRPRDMF MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 SDGTPHQVVIPAEQADIGWDVVDTAGWSPARMKEAIDAAAGHAFDLSTEI MMAR_3176|M.marinum_M DQDGLHQVLCGPESWEPEFFDVSDAPDPDAAAQSIILEIRGTSFDLSHGL MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 AHRTVEALAPLLGDSDVRDTGPAVDPTGAATPTPILRWLDEVGTAGSVLN MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 PLRATLFRNSLDEHVLVAVAHHIAADGSSLNPLLRDLTAAYTARCAGRVP MMAR_3176|M.marinum_M LGRAGLIKLNELRHFVFLVVHHIVCDGFSTLIAVRRVAEIYTALKSGSSI MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 GFHQGMSLVTPADADENTLRAAIAATVRRHHVLWAPPGRTASDIDIPGTP MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 DWVPLPVQYIDYALWQRAQFGDLEDPDSPIAGQLRYWQEALAGLPERLAL MMAR_3176|M.marinum_M PRSAYCSPEAVAEYDSRYKLSERYTSDKEFWTSYTRAWPEPLNAIRRPTA MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 PETRLLIADASDGIPAQAEKVARQLVSLLDTARIAFGWIRRPAAPGRLVV MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 PTDRPYPAVADHRGARVDIDWPASLQQQVSALARVHNATSFMVVQAGLAV MMAR_3176|M.marinum_M PRAATLRYSTILTG---------EVPGRLHAAADGAGTLLPVFFIAAVAG MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 IADHTVIDGVSLRILAEDIATAYGLIAEGRAVELPTPHTSWRAWAQRLAD MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 LLAKLGASCDVAVGFPIAGRGDPAL-----DDLVGFFVNTLVLRVDLSGD MMAR_3176|M.marinum_M CLSRLSSTSEFSVRLAVANRFGIAR-----KTPCLLSNTVPVRVNVPSGV MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TAAAGGFDADLEHWQQVCATTETPWGDRALDPAIDTVATESRLTVELPSA MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 PTVGEILARVRQRSLAAYEHQDVPFEILVERLNPTRSLAHHPLIQVMLTW MMAR_3176|M.marinum_M GFSNFASVLGREISSVLRHSRYPVTEIRDIGRLQMQRSQFGPVINVLPFF MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VTDAILTTVPDRIHGHVNDALVAALYLALRRWLHTRGVGADTLLVEMEGH MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 RGDDPTRLRLGELEVAALPIDIGTARMDLTFSLCERWTEEGRPAGIAGTV MMAR_3176|M.marinum_M SETHELPDSHGAFRDGSFG---ACDDLLISIYYDARELNNGEPGSVYIQI MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 GREGHLVDSDTAGLDLSNTVGWFTTLYPVALRDAEFDWQAAVSGGPQLGA MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 EFRTDVFDADTIRTL------TERLRRVLDVLTADPGRHLSSIEVLEDTE MMAR_3176|M.marinum_M DGNGLLYANEDLIRL------ADHLVSFLRAVSAEPQRRVDLVEIIDPVE MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 AVRSVKDQLRSVPSHGFSYGALRYLRDGTSGLEAAPQVLFNYLGRFGTAD MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 FARLDIFGNRAALGRSTTGASVPALFGAWAQRVPGAVAISSADRCWTYRE MMAR_3176|M.marinum_M RQRLLVECN--DTATAIPEATIPELFGAQVARVPESAAVHDDLEMLTYRE MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 RPWALANDTTAVLEDRDPGMPLPRLLEVNAEAVTTADG--SVLRATFSWP MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 VDETANRLAHLLIQHGVDRGQYVGLLLDRSAEAVVAILGVLKAGAAYVPM MMAR_3176|M.marinum_M LDVRASDLARGLAARGAGPEVIVAVALPRSARLVVALLAIAKTGAAYLPI MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 AHAVAEVDVRTLAGMWTDLLTAIASSDDVRGHSASDFDRVSVTADDVAEL MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 DPAVPAARIAFIVADADLRVVVTDAGSRSRLTGLGAAIVDLDDPALAD-- MMAR_3176|M.marinum_M DPNYPSERSAYILSDAAPQLLITDTPTAPTLPDTGVAVLILDTTLDTT-- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 ERRYPGLTDLLPLTPTQQGIYFHSTFSRDRDPYVVQQIVDITGPLDTERF MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 ----------------------------------------------YPAT MMAR_3176|M.marinum_M ----------------------------------------------EVSD MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 QRATESVAARHRALGAVFTTLSDGTPVAVHAATVAPDFDVLDARHAADPS MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 ----------EPAGPGPAAGDIAHVIYTSGTTGEPKGVAVSHRNITQLFA MMAR_3176|M.marinum_M RGIEATPGYCYQDSLGPGPDNLAYIMYTSGSTGHPKPVAITHRNVVALFT MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TVVAQRARWERERRFDLAAAPLTRYTLVRRRDDLHTMIETVHHIVADGWS MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 SLDTGITLGPDQVWSQCHSLAFDFSVWEIWAALLHGGRLVVVSDAVARSP MMAR_3176|M.marinum_M GFGWWRGLTDTDVWAWCHSPAFDVSAWELWGALLHGAQAVVVPWEVVRSP MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VPIVLDDLLTAYAGDDFDGPAPEFARFVDWLEQRDTDSDRAAWAPALEDI MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 DDLRRLLIRERVTVLTQTPSAAGALSPQGLDSVALVIGAEPCPPELV--- MMAR_3176|M.marinum_M RELWQLVVDKRITVLSQTPSAFYELIRVQRELPASAESSALRMVVFAGEA MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TEPTRLAAADGARGRTTGSGFGTRTVTLQSRSAVADAANGAAVTVGTLLH MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------DRWAP---------------DRVMINVYGPTETTMWV MMAR_3176|M.marinum_M LDPSRLRGWYPGQGEQAP---------------ALINMYGITETTVHTTY MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TAWGLALGRLTGRDDVVFGTVVSGRGADVHGIESMVGLLVNTVPVRVAWS MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 SHSRPLAAGSGAPPIGSPVAGASFFVLDPWLCPAPVGVTGELYVAGAGVG MMAR_3176|M.marinum_M LELTSEDAERGVSPIGGPLGNVRVFVLDAGLCPVPVGVAGELYVAGAQVA MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 ADDTGADVAGRLAAVESTLLEHHHLPLTEAHRLAGVGELFDTLVVIENLG MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 AGYVGR--------AALTASRFVACPFGGTGTRMYRTGDLVRWGADGQLH MMAR_3176|M.marinum_M RGYRGR--------VGLTAQRFVACPFGPAGSRMYRSGDLVRWNSSGVLE MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 ATTHTRGDLTLGDIGVIEAPHYPLTLMISVRDTITVTVTNDREHVSDVLA MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 YVGRADEQVKIRGYRIELGEIRSALTDLDGVEQAAVIAREDSPGHK---- MMAR_3176|M.marinum_M FVGRADDQVKIRGFRIEPGEVEAVLAAHPRVAQAAVAAYSTSGGLEGISD MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 DTAVAAFTEVLTALTADPGVSPGDIALPAPQATAPPTQAPQTVTDLIAAA MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M KQLVGYIVPDREALLARDAAREAGLVQQWAQVYGGVYSGLASQVPAVLGE MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 IAEHRDDIALVVGETEWTYGQLGARAGELAAALAEAGVRRGDIVALATAR MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M DFRGWVSSYTGAPIPLDQMGEWRAAAVERIVGLSPGRVLEIGVGTGLLLA MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 SADLVAAIWAIIAAGAAYLPVDLAYPRTRIEYMLRHARPTAVIADGVGAH MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M QLAPDCVEYWGTDFSASTIEMLQAAVVSRPWGDRVRLRVQPADSAEGLPA MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VVSGALPADTIVVSTTATHAAVPFTPVPVDGADAVSVLYTSGSTGEPKAV MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M GHFDVVVLNSVIQYFPSAGYLLDVLAVAMRLLAPGGALFIGDVRNLGLLR MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VGTHAALANRLAWAVEAWPAATRIAKSPLSFIDGTTELLAGLAAGARTVL MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M AFTTKVLCTGTAGANDAAAVMRERVRREMLAEQELLLAPEFFSALPQYLP MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 AGDETARDGRRLAQLVAAHGVEQLLAVPSLAAVLADERTEDVAELNRWIV MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M DIAAVDIQLKRMQAVNELSCYRYEVVLRKGPVGVRSLAGLSALPWQRFGG MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 SGEALEPRHLHALRTACPTAEIVNSYGSSEVAGDVLAGVQDDAGITLGAA MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M PAALGEYLQEHRPAGLRVSGIPHEAVWPDVAMAHALAQAGDRVLVSQIGA MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VPGAGIRILDSRLRQLPAGVIGEIYVTGGQLARGYLGRPGQTATRFVAAP MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M DPSPSDAVLPHHLHQLGREAGYSVAVTFSSTPGLMDVLLVDSLDAQPLPA MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 GGERMYRTGDLGALLPGGRVVFAGRADDQLKINGHRVEPGEIESVLARQP MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 ---------------RLVAYLTGTADPAQVRTQLADRLPGYMLPSAVLAL MMAR_3176|M.marinum_M LSDLYLPGAPIGSLAGYVNDPSAIELANEVRRWVGERLPEYMVPAAVMVV MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 GVREAAVIGTGTQLAAFVVLESDAPGAGDLLTAVSAELPGHLVPSSLRPV MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 DALPLTVNGKLDTRALPAPELRAENRYRAPQNPTEESLADVYARLLGLER MMAR_3176|M.marinum_M EGLPLTANGKLDRRALPAPQFTSTAAYRGPRDQREAVLAGLFAEVLGVAQ MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 DAIPLLPNGKRDNNALRSLLVPGESTGTAPTNDVERAVLDVMTGVLGRDP MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 VGVDDSFFELGGDSLSAMRLITAVNAELDADLTVRALFEAPTVAQLAPRV MMAR_3176|M.marinum_M VGIDDRFFDLGGHSLSVTRLVARIRAELNVEVPIRAVFNAPTVAELAQWI MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LGADDDFFAVGGDSISAIRVTSRLARAG-YHIATEDVFRGRTAAGVAALV MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 AAG--TGRAGRLVAAERPAVLPLSFAQSR-----------------LWFI MMAR_3176|M.marinum_M SVHGGARVRAALVARERPARLPLSYAQTR-----------------LWFL MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 DTVESLAHDAAIEPFATVRLSPQTIDRIRESGQVEDIWAMSPLQLGVYYQ MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 DQLHGPSPVYNMAVALNLRGPLDTDALGAALGDVVARHESLRT------- MMAR_3176|M.marinum_M HKYEGPSATYNIPLAVRLTGEIDAAALCAAIVDVVARHESLRT------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 STLADAGPTYIAQNVFEFDRRIDVDAMRRAFTALLRRHPQLRAGFRTVEH MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 --LFPAPDGAPRQVVLEAERAEVDWQVVDAARWPASWLAEATHEAARYTF MMAR_3176|M.marinum_M --LFTETDGIACQQVLPAEDLDVPVTVTEVTSDELITAAADTVG---YRF MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 AEPEPAPDATPVVQVVVTDPPSDLTVVDLTDQDDPAAAQHIVDTDRTAPF MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 DLATEIPLRAWLFRRNHDEHVLVAVVHHIAADGWSLTPLVRDLGAAYASR MMAR_3176|M.marinum_M DLATEIPIRAQLLQVSSTEHVLVVVVHHIAADGASMVPLARDVATAYTAR MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 DVATPPLLRLTVIRLPGGRDRMLFTYHFLLFDGWSRELVLRDLFALYDS- MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 CRGRPPDWAPLPVQYADYTLWQRAQFGDLDDPDSPIATQLQYWQRALAGM MMAR_3176|M.marinum_M LVGRAPDWAPLAVQYADYTLWQHDVLGSEDDPDSVLSQQFDYWRAELADA MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 -----DAQHGAIAPHGDLVVRHLQWLATDGDPQASGARDAWRDLLAGLTE MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 PERVALPTDRPYPLVADHLGASVQVHWPAELQQHIAQLARTHNATSFMVV MMAR_3176|M.marinum_M PKHIVLPTDRPRPPQQSFRGDQVALNIDAGLRTRIEALARQSGTTPSMVL MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 PTLASGVSPDHPDARPGTEPGRIVVRVPEDVTTQLHTCATAHGATLNSVV MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 QAALAVLLSTLSANPDVAVGFPIAGRRDPAL--DDVVGFFVNTLVLRVDL MMAR_3176|M.marinum_M QAALMVLLHKLGAGDDLTIGGPIAGRTDDAL--NDLIGFFVNTWVLRVNT MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TAAVALVTGYHAGTTDVVIGTTVAGRPGHLVGIDETIGLFLNTVPVRVDM MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 ADDPSIAELLGQVRHRSLQAYENQDVPFELLVERLNPTRSLAHHPLVQVM MMAR_3176|M.marinum_M SGNPSFGELLEQVRDKALAAYENQDAPFERLVELLNPSRSTAHHPLFQIS MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 SPTRSVAAAMASIGEQRVAMMRHDHLGLGQIQRAAGDSGSALFDSLLVLQ MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 LAWQNNDPVDVSLG-DVHVTPMPLENQVARMDLVWSLAERWTADGRPDGI MMAR_3176|M.marinum_M FALQNNPLPAIESSPGLGIEILNPPTHTAKFDLFINLVDLPSPTKDPQPL MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 NFLDDDTFTDLESRHGIVDVSYHDTTHFPLTWVLTP------------GR MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 DGTVEFRTDVFDAASIETLVRRLQRVLLAMTADPARPVSSIDILDEPEYA MMAR_3176|M.marinum_M AGTIEYATDLFDRGTIEKFATSYLHILDIVTTNPQQQIDLVEIIDPAERQ MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 ELAIKLEHRVVDDARATEMVEQLVTVLRTIAAEPDTAVGAVDLIGADRRA MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 HLDALGNRAALTRPATGWVSISQLFAAQVARTPEAVAISCGERSWTYREL MMAR_3176|M.marinum_M RLLVECN---DTATAIPETTIAELFAAQVARVPESAAVHDDLETLTYREL MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 QLERRWSSTERPLEP---VTIAELLARRAEQNPDDVALVFGAQSVTYREF MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 DSSANRLARVLAGRGARPGERVAVLVPRSAGAVVSILAVLKTGAAYVPID MMAR_3176|M.marinum_M DDRATDLARGLAARGAGPEAIVAVALPRSARLVVALLAIAKTGAAYLPID MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 DDRVSQFARHLRARGAAPETFVALALPRSIDMVVALFAVLRAGAAYLPLE MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 PGLPSARIDFMLADAVPVVTVTTAELRASA-----GDPDRVVAIDDPAPH MMAR_3176|M.marinum_M PNYPSERSAYILSDAAPQLLITDTPTAPTL-----PDTGVAVLILDTTLD MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LDLPIDRLRTIIDNAEPVLLVTTTDRTELIGHARARGADVIALDDAETAA MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 VPRIGGR-------------AAPAPDDIAYVIYTSGTTGVPKGVAVTHHN MMAR_3176|M.marinum_M TTEVSDRGIEATPAHRDRDCPQPGPDNLAYIMYTSGSTGHPKAVAITHHN MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TLADTPAHPLTAGELGAFASDSTRLNHPAYLIYTSGSTGRPKGVLTGYAG MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 VTQLLG---------SLDDRLGLGR-VWSQCHSLAFDFSVWEIFGALLRG MMAR_3176|M.marinum_M VINMAV---------LCGWLQGAAQGRVAMAASPGFDASVLEVWPALLRG MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LTNMYFNHREAIFAPTVARAGSAEQLRIAHTVSFSFDMSWEELFWLVEGH MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 GRLVIVP-----DDVVRSPEDLHALLIG--EGVTVLSQTPSAAAALSPER MMAR_3176|M.marinum_M NALVVWAGQMDVAALRWLITDRGATSMF--VPTALLHQLADETPDCLEQM MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 QVHVCDEELRRDAPALVAYCHRHRIDVINVTPTYAHHLFDAGLLDDGAHT MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 LESVALVLGGEACPVELMDRWAPGRLMVNQYGPTETTLYATMTTPLRAG- MMAR_3176|M.marinum_M DHLVTGGDVLSPVAVGKVLVAHPQLTIVNAYGPTEGTVAATMYPITAADG MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 PPLVLLGGEAVGDGVWSALRDHPDSAGYNLYGPTEYTIN-----TLGGGT MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 --GAAVPIGSPVPGAALFVLDGRLRRVPPGVVGELYVAGRGVAAGYLGRA MMAR_3176|M.marinum_M LDGGSVPIGGPLGNVRVFVLDAGLCPVPVGVAGELYVAGAQVARGYRGRV MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 DDSDTPTVGQPIWNTRGYILDAALRPVPDGAVGELYIAGTGLALGYHRRA MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 ALTASRFVACPFGGTGTRMYRTGDLAR--WGADGQLHYVGRADEQVKIRG MMAR_3176|M.marinum_M GLTAQRFVACPFGPAGSRMYRSGDLVR--WNSSGVLEFVGRADDQVKIRG MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 GLTAATMVADPYVPGG-RMYRTGDLVRRRPGSAELLDYLGRVDDQVKIRG MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 FRIELGEIRSVLAGLDGVEQAAVIARDDGAGHPRLVAYITGT-------- MMAR_3176|M.marinum_M FRIEPGEVEAVLAAHPRVAQAAVAAYSTSGGLEGISDKQLVG-------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 YRVELGEIESVLTRADGVARCAVVARATGANPPVKTLAAYVIPDRWPAED MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -ADPAELRAQLADRLPGYMVPSAVVVLDALPLTGNGKLDTRALPAPDYAG MMAR_3176|M.marinum_M -YIVPDREALLARDAAREAGLVQQWAQVYGGVYSGLASQVPAVLGEDFRG MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 AAFITGLRDHLARVLPGYMVPTRYGIVDTLPLTINGKLDVAALPEPIAAT MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 GRY-RAPGDAIEEILAGIYAQVLGVERVGVDDSFFDLGGDSILSMQVVAR MMAR_3176|M.marinum_M WVS-SYTGAPIPLDQMGEWRAAAVERIVGLSPGRVLEIGVGTG--LLLAQ MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 SGTGRTPRTDREATLLEIVASVLGIDGIGVDDDFFTLGGDSISSISVCGR MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 ARAAGVMCTARDVFVEQTVARLARVVTVAAADGELGAADEGIGPVQPTPI MMAR_3176|M.marinum_M LAPDCVEYWGTDFSASTIEMLQAAVVSRPWGDRVRLRVQPADSAEGLPAG MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 ARKAGLNITPRDVFRRRTIAALAASADTTQTP--ESGPDTGTGAITATPM MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 MRWLQDIDGPIDEFNQTMVLAAPAGVSQSDVAVVLQALLDRHPMLRLCLD MMAR_3176|M.marinum_M HFDVVVLNSVIQYFPSAGYLLDVLAVAMRLLAPGGALFIGDVRNLGLLRA MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LAETAQANTPLTNFYQAMVLATPAGITAHEVQRVLQTVVDAHAMLRARLV MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 DDGAGGWDLHVPPPGSVDARPIL-RTVDVLSEAALARARARLNPGAGLML MMAR_3176|M.marinum_M FTTKVLCTGTAGANDAAAVMRER-VRREMLAEQELLLAPEFFSALPQYLP MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TTATGWTLTVPDQTAAIGLTVRSGALTSDCVEAEKAAAAAELDPRAGNMV MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 SAVWASETSQL---ALVVHHLAVDGVSWRTLIEDINIAWAQHHSGQEIAL MMAR_3176|M.marinum_M DIAAVDIQLKR---MQAVNELSCYRYEVVLRKGPVGVRSLAGLSALPWQR MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 RAVWFDAPEASGQLLLVIHHLVIDGVSWRILSEDLSRAWNDLAAGRDVAA MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 PVPGTSFARWSSILAEYAKSPAVVAAAAAWQQVVATPAVLPAVGPDDTYA MMAR_3176|M.marinum_M FGGPAALGEYLQEHRPAGLRVSGIPHEAVWPDVAMAHALAQAGDRVLVSQ MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 DAVPTSFHTWANALAQRTFDDESEYWADVLATPDPDLGSRPPDPAIDTAD MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 SAGQLSASLDVQTTRLLLGEVPAAFHAGVQDILLIAFGLACTEFVGGG-- MMAR_3176|M.marinum_M IGADPSPSDAVLPHHLHQLGREAGYSVAVTFSSTPGLMDVLLVDSLDA-- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TVRSHEVTLASDVTEALLTSVPAAMHGGVNDVLLTGLAVALAQWRADRGH MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 ----APIGIDVEGHGRHEEIASGVDLSRTVGWFTTKYPVALRMSRRLDWA MMAR_3176|M.marinum_M ----QPLPALSDLYLPGAPIGSLAGYVNDPSAIELANEVRRWVGERLPEY MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 SQNTAAVISLEGHGRESDLVAADLDLSRTVGWFTSIYPVRIDPGP-LEWD MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 RVVAGEAALGAVIKDAKEQLRALPDGLSYGLLRYLNPEIEVQGPDPVIGF MMAR_3176|M.marinum_M MVPAAVMVVEGLPLTANGKLDRR-ALPAPQFTSTAAYRGPRDQREAVLAG MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TVRSAGAELAAAAKAVKEQLRAVPNRGLG-YGVLRHLHGALDGTPPQILF MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 NYLGRLGGAAADLSDEHWRLSPDSPSVSAAAAAIPLPLGHTVELNAGTMD MMAR_3176|M.marinum_M LFAEVLGVAQVGIDDRFFDLGGHSLSVTRLVARIRAELNVEVPIRAVFNA MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 NYLGRFTGGSGNDWRPVAGIGALTEGVDPSNPAMSLEINALAEERPDGTV MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 TDAGPQLHANWTWARSVLTDEQLNRLSRLWFEALTGICAHVQAGGGGLTP MMAR_3176|M.marinum_M PTVAELAQWISVHG-----------------------GARVRAALVARER MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LSMTLAWPGG--------LLDADDVSELGSMWADVLVALTRCDALRGHTP MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 SDIAPTRLDQGRIEQLERRYDVADILPLTPLQQGLLFHATGSHAEGDVYA MMAR_3176|M.marinum_M PARLPLSYAQTRLWFLHKYEGPSATYNIPLAVRLTGEIDAAALCAAIVDV MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 SDFGLVTVSQDDIDGWDRLGEVEEVLPLLPLQEGMYFHSMFGDPATDTYR MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 VQLSVTLRGALDPHRLHRALHTVVTRHPNLAARFCPELGEPVQIIPAEPE MMAR_3176|M.marinum_M VARHESLRTLFTETDGIACQQVLPAEDLDVPVTVTEVTSDELITAAADTV MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VQQIAQLSGPVDPEVLRTSLTVVMRRHQALRASFNELTDG-----RVAQV MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 IAWRYLELDASDVDEQLEQLSADERAAVRELGDRPPFGAALIRTADTEHR MMAR_3176|M.marinum_M GYRFDLATEIPIRAQLLQVSSTEHVLVVVVHHIAADGASMVPLARDVATA MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 IWSDVPVQLTVVDTDDLESIAAEELARPFNLAEAPLVRYMLVRLGDDDHR MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 FVLTVHHLVMDGWSLPVLLQEIFACYYGARLPAPAPYRGFVTW------L MMAR_3176|M.marinum_M YTARLVGRAPDWAPLAVQYADYTLWQHDVLGSEDDPDSVLSQQ------F MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LVQTMHHIIADGWSYPVLFGDIVDHYNAAIGVGSAPQPITVTLRDHIETV MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 AARDVPAARAAWRAVLDGFDTPTLVAPRGADAPGRRGVASFRMAAETTSA MMAR_3176|M.marinum_M DYWRAELADAPKHIVLPTDRPRPPQQSFRGDQVALNIDAGLRTRIEALAR MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TDRDRGAARQAWEQALAGAEPTALVPRPDGAPVGEHRSVVRRLDSARTAA MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 VSELARRRRTTVNTVLQAAWAQLLMMLTGQHDVAFGTAVSGRPAELPGAE MMAR_3176|M.marinum_M QSGTTPSMVLQAALMVLLHKLGAGDDLTIGGPIAGRTDDALNDLIGFFVN MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VGRAARVHGVTVGTVLHGAWGLMLGRLLGRNRVVFGSTVSGRGGDLAGTE MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -----------------------------------------------MHR Rv0101|M.tuberculosis_H37Rv -----------------------------------------------MHR MAV_3239|M.avium_104 SMVGLLINTVPVRARAAAATTIADLLDQLQCAHNDTVEHQHL-GLNEIHR MMAR_3176|M.marinum_M TWVLRVNTSGNPSFGELLEQVRDKALAAYENQDAPFERLVEL-LNPSRST MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 SIVGLLINTIPVPMSWEPHATLASALIDLQDQQSALLDAQQMGLAELARL MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 VR------------------------------------------------ Rv0101|M.tuberculosis_H37Rv VR------------------------------------------------ MAV_3239|M.avium_104 VTGQDQLFDTLLVYENYPIDTAALSAADDLTATEFSCHDYNHYPLSLQVV MMAR_3176|M.marinum_M AHHPLFQISFAFQNDLPAIDFPGLGIEVLSAPTHTARFDLAIVLVDLPSP MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 AGVREFFDTMVIVENFPSTSSAEHTDPRAVAFRGFTGTDSPHYPVSFVAY MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -----------------------LSRSQRNLYNGVRQDNNP--------- Rv0101|M.tuberculosis_H37Rv -----------------------LSRSQRNLYNGVRQDNNP--------- MAV_3239|M.avium_104 PGDELGLRLEFDTDVFDPAAIDTLADRLRRLLAAMPADPDRPLRSLDLLD MMAR_3176|M.marinum_M TKDPQPLAGTIEYATDLFDRGTIEKFATSYLHILDIVTTNPQQQIDLVEI MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 ADDQLTVEIKYDAGVVTPEQAERYAERVERILTAFAETPDLPVSRIDLRT MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -----------------------------------MTGQSGFAVVGYAVR Mb0104|M.bovis_AF2122/97 ----------------------------------------ALYLIGKSYR Rv0101|M.tuberculosis_H37Rv ----------------------------------------ALYLIGKSYR MAV_3239|M.avium_104 STEHTRLQRWGNRPALSRPATGPSLPELFTAQVANAPHAVALRCAGRSMT MMAR_3176|M.marinum_M IDPAERQRLLVECNDTATAIPETTIAELFAAQVARVPESAAVHDDLETLT MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 NAERQFTAG-----HASRPGPGRTLGASFAEVAATYPDAVAVSCGDTRLT MAB_2258|M.abscessus_ATCC_1997 ---------------------------------------------MTAVD TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 FPGAADAR----------------EFWDVLAEGRDAVSEVPADRWDVDEF Mb0104|M.bovis_AF2122/97 FRRLELAR----------------FLAALHATVLDNPVQLCVLENSGADY Rv0101|M.tuberculosis_H37Rv FRRLELAR----------------FLAALHATVLDNPVQLCVLENSGADY MAV_3239|M.avium_104 YRELDEASTRLAHLLAGHGATPGCFVALLFSRSAEAIVAMLAVLKTGAAY MMAR_3176|M.marinum_M YRELDDRATDLARGLAARGAGPEAIVAVALPRSARLVVALLAIAKTGAAY MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 YRELDDRAAAVAATLAERGVGAESRVAIALPRSADLIVAVLAVIKAGGTY MAB_2258|M.abscessus_ATCC_1997 YRPAPESGEEIILFRASFAQQRMWFLSRLEPGSHYYNVPIVLHFRGAVRR TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 FDADPDAAGK---------------------------------------- Mb0104|M.bovis_AF2122/97 PDLVPRLRFG---------------------------------------- Rv0101|M.tuberculosis_H37Rv PDLVPRLRFG---------------------------------------- MAV_3239|M.avium_104 LPIDPALPATRIEFMLGDAAPVVAVSTAGLRARLEAF------------- MMAR_3176|M.marinum_M LPIDPNYPSERSAYILSDAAPQLLITDTPTAPTLPDTGVAVLILDTTLDT MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VPIDIGAPAARVQHILADSAPVCLLTDTAERFTG---------------- MAB_2258|M.abscessus_ATCC_1997 DALQR--------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 ----------MVSRRAG-----------FVDDVAGFDAPFFGVS------ Mb0104|M.bovis_AF2122/97 ----------DIVRVGS----------ADEHLQSTWCSG---ILGKP--- Rv0101|M.tuberculosis_H37Rv ----------DIVRVGS----------ADEHLQSTWCSG---ILGKP--- MAV_3239|M.avium_104 -----GLPVVDVAATGAQPGGPLPPPAPDNIAYLLYTSG---TTGVPKGV MMAR_3176|M.marinum_M SPDTTEVSDRGIEATPAHRDRDCPQPGPDNLAYIMYTSG-STGHPKPVAI MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 -----VPHVILAEAAQNPARPQAPTVSPDHAAYVIYTSGSTGVPKGVEVT MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 AVTHRNVAQLLESLHASLPGTGVWSQCHSYGFDVSVQEIWGALAGGGRLV MMAR_3176|M.marinum_M THRNVVALFTGFGWWRGLTDTDVWAWCHSPAFDVSAWELWGALLHGAQAV MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 HRNVAALFAGTTSGLYDFGPDDVWTMFHSAAFDFSVWELWGPLLHGGRLV MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -AREAMFMDPQ-----------------------------HRLVLETAWS Mb0104|M.bovis_AF2122/97 LVRHTVHTDPN--------GYVTGLDVHT-----------HHILLDGG-- Rv0101|M.tuberculosis_H37Rv LVRHTVHTDPN--------GYVTGLDVHT-----------HHILLDGG-- MAV_3239|M.avium_104 VVPESVTSSPDELHALLIAENVTVLSQTPSALAALSPRNLHAALVIGGEP MMAR_3176|M.marinum_M VVPWEVVRSPRELWQLVVDKRITVLSQTPSAFYELIRVQRELPASAESSA MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VVEHDVARDPERFVDLLARERVTVLNQTPSAFYP---LLEADARLRRQLA MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 ----------------------------AVEHAGIAPEALAGTRTGVFLG Mb0104|M.bovis_AF2122/97 -------------------------------ATGTIEADLARYLTTDPAG Rv0101|M.tuberculosis_H37Rv -------------------------------ATGTIEADLARYLTTDPAG MAV_3239|M.avium_104 CPAALAD--------------RWAPGRVMINAYGPTETTVDAVLSTPLAA MMAR_3176|M.marinum_M LRMVVFAGEALDPSRLRGWYPGQGEQAPALINMYGITETTVHTTYLELTS MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LRYVIFGGEALDVRRLAPWYANHESHSPRLVNMYGITETCVHVSHRALDT MAB_2258|M.abscessus_ATCC_1997 -----------------------------ALAGMVSRHEILRTTFVEVEG TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 LSTHEFLGMLIAHTGYEDVD------------------------------ Mb0104|M.bovis_AF2122/97 -------ETPSVGAG---LAKLR--------------------------- Rv0101|M.tuberculosis_H37Rv -------ETPSVGAG---LAKLR--------------------------- MAV_3239|M.avium_104 GAGAPPLGSPVAGAT---LFVLDGWLRPVPAGVTGELYIAGAGVAAGYLG MMAR_3176|M.marinum_M EDAERGVSPIGGPLGNVRVFVLDAGLCPVPVGVAGELYVAGAQVARGYRG MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 ADTGAAGSVIGGPLPGLRIHLLDNNLQPVPAGVVGEMYIAGGQVARGYTG MAB_2258|M.abscessus_ATCC_1997 EVMQAVAADSAVPVPLTAIES----------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 ----------------------------------------------IYSG Mb0104|M.bovis_AF2122/97 ------------------------------------------------EA Rv0101|M.tuberculosis_H37Rv ------------------------------------------------EA MAV_3239|M.avium_104 RAGLTAARFVACPFGGAGARMYRTGDLVRWDRDGRLHYVARADQQVKIRG MMAR_3176|M.marinum_M RVGLTAQRFVACPFGPAGSRMYRSGDLVRWNSSGVLEFVGRADDQVKIRG MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 RPGLTATRFVANPFDGAGERLYRSGDLAMWTDAGELVYLGRSDAQVKVRG MAB_2258|M.abscessus_ATCC_1997 -----------------------------------------------SAA TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 TGTSPAAAAGRVSFRMGLQGPAVAVDTACSSSLVAVHQACQ--------- Mb0104|M.bovis_AF2122/97 HRRETAKVEESRGRLSAVVQRELADEAYHGGHGHSVSDAPG--------- Rv0101|M.tuberculosis_H37Rv HRRETAKVEESRGRLSAVVQRELADEAYHGGHGHSVSDAPG--------- MAV_3239|M.avium_104 HRIELGEIHSALAELDGVEQAAVIAREDRPGEKRIVGYLTG--------- MMAR_3176|M.marinum_M FRIEPGEVEAVLAAHPRVAQAAVAAYSTSGGLEGISDKQLVGYIVAESVT MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 YRIELGEVEAALVTLPGVTNAAADVRHDDTGRARLIGYVVG--------- MAB_2258|M.abscessus_ATCC_1997 HSLPPIARPEVRTAVLELVCTPFDLSSGPLLRAHLLDVQDG--------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 --------------ALRDGDCDTALVGGVNVILTPVPMINLTRARMLA-- Mb0104|M.bovis_AF2122/97 --------------TAAKGVLHESATICGNAFDAILTLSEAQR----VPL Rv0101|M.tuberculosis_H37Rv --------------TAAKGVLHESATICGNAFDAILTLSEAQR----VPL MAV_3239|M.avium_104 --------------TADPAAIRARLAERLPAYMVPAAVLAIEA----LPL MMAR_3176|M.marinum_M DAGPEIASGAADEYAELANEVRRWVGERLPEYMVPAAVMVVEGLPLTANG MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 -------------DALDIGALRSTLAERLPDYMVPSVLLRLDVLPLTVNG MAB_2258|M.abscessus_ATCC_1997 ----------------EYLLVLTMHHIIVDGWSIGVICKELR-------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 N------------------------------------------------- Rv0101|M.tuberculosis_H37Rv N------------------------------------------------- MAV_3239|M.avium_104 TPNGKLDARALPAPEYAGGAYRAPSTPTEEIIAGIYT------------- MMAR_3176|M.marinum_M KLDRRGLPAPQFSG---AAVYRGPRDEREAVLAGLFA------------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 KLDRAALPDPEPVEQAPAPVAGTGTASLLAGLCTEILGTTVGVEDDFFTA MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 ------------------------------------------PDGRCKTF Mb0104|M.bovis_AF2122/97 -------------------------------------------VLVAAAA Rv0101|M.tuberculosis_H37Rv -------------------------------------------VLVAAAA MAV_3239|M.avium_104 ------------------QVLGLHRVGVDDSFFDLGGDSLSAMRVIAAVN MMAR_3176|M.marinum_M ------------------EVLGVTQVGIDDRFFDLGGHSLSVTRLVARIR MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 GGDSIIAIQLVNRARREGVRITPQQVFVHRTPAALASVLDTGSVAAPDAT MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------ELYASEV TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 DAAADGYVRGEGCGVVVLKRTGDALRDGD--RIR---------------- Mb0104|M.bovis_AF2122/97 VAVDA--SLRQNTETLLVHTVDNRFGDS---------------------- Rv0101|M.tuberculosis_H37Rv VAVDA--SLRQNTETLLVHTVDNRFGDS---------------------- MAV_3239|M.avium_104 AGLDARLSVRVLFEAPTIAQLAARLGEGG--HRFAAVVAAERPAVVPLSF MMAR_3176|M.marinum_M AELNVEVPIRAVFNAPTVAELAEWISVHGGARVRAALVARERPARLPLSY MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 PDEDAGPDLGEVMLTPIVQRLAELGGTVTRFNQSELLRTPAGATVARLET MAB_2258|M.abscessus_ATCC_1997 GGIPAALPSLELQIGDLAEQEHELMSAPTR-------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -----------------------------------------AVIRGSAVN Mb0104|M.bovis_AF2122/97 -----------------------------------------------DLN Rv0101|M.tuberculosis_H37Rv -----------------------------------------------DLN MAV_3239|M.avium_104 AQSRLWFIGQLHGPSPVYNMVAALRLHGPVDIGALGAALHDVVTRHESLR MMAR_3176|M.marinum_M AQTRLWFLHKYEGPSATYNIPLAVRLTGEIDAVALCAAIVDVVARHESLR MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 AINAVIARHDALRIRLHRPAPMLWSLETTAAAPVSITRIDAHGFDDEQLR MAB_2258|M.abscessus_ATCC_1997 ---------------------------------------------ERHLA TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 QDGASGGLTVPNG------------------------------------- Mb0104|M.bovis_AF2122/97 VATCLVNSVAQTVRFPP--------------------------------- Rv0101|M.tuberculosis_H37Rv VATCLVNSVAQTVRFPP--------------------------------- MAV_3239|M.avium_104 TVFAATDGTPAQVVLPPDRADIGWQVIDASGWSPARVDDVIRDTARHTFD MMAR_3176|M.marinum_M TLFTESDGIPCQQVLAVEDVDVPVVVTEVAAQG---LAAAAIEAVGYRFD MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TVIATESDAAADRLDPENGVVVVAVWFDRGTDTQGRLLLVVHHLAVDGVS MAB_2258|M.abscessus_ATCC_1997 YWRSQLAGDLSAPALPFD-------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------VAQQHV------------- Mb0104|M.bovis_AF2122/97 -------------------------------FASVSD------------- Rv0101|M.tuberculosis_H37Rv -------------------------------FASVSD------------- MAV_3239|M.avium_104 LAAEIPLRAVLLRCGDEEHLLVAVVHHIAADGWSLTP------------- MMAR_3176|M.marinum_M LATEIPVRAELLRVSSAEHVLVVVVHHIAADGASLVP------------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 WRILLDDLAEAYRQALSGQRVAPAPVTTSLRQYARTVNENAQHSSRLTEF MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M -------------------------------------------------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 EHWTEVLAPGGELVATADVVTLTVGATRDHEIRLSTEDTAPLLTTVPAAA MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M -------------------------------------------------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 NADVTETLVAALHLAVSRWRAARGEAADAPLVLSLERHGRDGWPDDVDLS MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M -------------------------------------------------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 RTVGWFTSIAPVRLPAPGEDLLNTLKAVKESLRAAPDGGLGFGQLRYCNP MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M -------------------------------------------------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 RTSAVLARLGTPQLLFNYLGRWAADACDDWASAPEVDALRTEPNPDLGTP MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M -------------------------------------------------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 YLVEVNAICDDTVDGPRLRATLTYADGELDEPSVAELGELWVAALRELGS MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M -------------------------------------------------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LATGGDAALTPSDLPLVTLTQEHIDRVTGAVPGNVETIWPLSPLQEGVYL MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M -------------------------------------------------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 QARYATAAVYIVQNVFDFAEPVDTTALRTAYSAVMARNPVLRSAFWADDL MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 ------------------------------IADALRRAGLGGGEVD---- Mb0104|M.bovis_AF2122/97 ------------------------------VVRTLDRG-----YVKAVR- Rv0101|M.tuberculosis_H37Rv ------------------------------VVRTLDRG-----YVKAVR- MAV_3239|M.avium_104 ------------------------------LVRDLARA-----YASRSAG MMAR_3176|M.marinum_M ------------------------------LARDVATA-----YTARLVG MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 PQPVAAIVADPVCEPRVVDLGGLPATQVERRVEEITADDRQQTFDLAAAP MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 RVPDWVPLPVQYVDYTLWQRAQFGDLDDPHSLIAGQLRYWESALAGMPER MMAR_3176|M.marinum_M RAPDWAPLAVQYADYTLWQHDVLGSEDDPDSVLSQQFDYWRAELADAPKH MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LARMTVLRTPDRDRLIFSYHFLLLDGWSREQLLRELFAEYTAARGGAVAQ MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 ---------YLEAHGTGTSLGDPIEVQAAAAAFGDGRDPDRPLLIG---S Mb0104|M.bovis_AF2122/97 ------RRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAP-------G Rv0101|M.tuberculosis_H37Rv ------RRWLREEHYRRMYLAINRTSHVEALTLNFIREPCAP-------G MAV_3239|M.avium_104 LELPTDRPYPVVADFRGASVAVEWPAQLQQQISRLAGAHNATSFMVVQAA MMAR_3176|M.marinum_M IALPTDRPRPPQQSFRGDQVALNIDAGLRTRIEALARQSGTTPSMVLQAA MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LPAPTADFTDYLRWLARQDRDVSAREWSEALRDLEAPTLLVPDAVGTDPT MAB_2258|M.abscessus_ATCC_1997 ------RDRPSRNVFHGATVDFTLSPSDTAVIAAFGRDRDATIFATLLAA TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 VKTNIGHLEAASGIAG------------------LIKVVLSLEHETLP-- Mb0104|M.bovis_AF2122/97 LRPFLSEVPIATDIGP--------------VEGMTVASVLDEEQRTLN-- Rv0101|M.tuberculosis_H37Rv LRPFLSEVPIATDIGP--------------VEGMTVASVLDEEQRTLN-- MAV_3239|M.avium_104 LAVLLAKVSASSDVAVGFPIAGRRDPALDDVVGFFVNTLVLRVDVSGDPT MMAR_3176|M.marinum_M LMVLLHKLGAGDDLTIGGPIAGRTDDALNDLIGFFVNTWVLRVNTSGNPC MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LALRLEFLLSEADTAALTAAARSAGVTLNALISTALAMVLAYETGRDDVV MAB_2258|M.abscessus_ATCC_1997 FYALLYRYSGSDDQVVGAPMANREDHRVSALIGLFVNTVPLRARVDPNAG TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 ----VHLHLRRPS------------PHIPWERLPVRVVAEATPWQRNDRP Mb0104|M.bovis_AF2122/97 ----LAIWNRADL------------PACKTHPKVAERIAAALESMAAMWD Rv0101|M.tuberculosis_H37Rv ----LAIWNRADL------------PACKTHPKVAERIAAALESMAAMWD MAV_3239|M.avium_104 VAELLARVRQRSL------------AAYEHQDVPFEVLVERLNPARSLAH MMAR_3176|M.marinum_M FGELLEQVRDKAL------------AAYENQDAPFERLVELLNPSRSTAH MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 FGSTVAGRPTDLDGIDSVIGLFLNTVPTRVRLAPHRTVADTMRAVQSDRL MAB_2258|M.abscessus_ATCC_1997 FAALVSHVREVTLG------------AYEHQELPLEQIIDEVAPTRLPGR TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 RIAGVSSFGFSGTNA----------------------HVLLEEAPVA--- Mb0104|M.bovis_AF2122/97 RPIAMIVNDWF----GIGP-----------------DGTRCQGDWPA--- Rv0101|M.tuberculosis_H37Rv RPIAMIVNDWF----GIGP-----------------DGTRCQGDWPA--- MAV_3239|M.avium_104 HPLVQVMLAWQ----NIEPTELSLGQVRVIPLPVDTRTARMDLAWSL--- MMAR_3176|M.marinum_M HPLFQISFAFQNDLPAIDFPGLG-----IEVLSAPTHTARFDLAIVL--- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 RLMDHEYLGLGDIQRAVSTGGGPLFDSLYVLQNFLDDDTFTDMEAQYGIV MAB_2258|M.abscessus_ATCC_1997 NPMVAVLFAMQSPPPVDLDFAGTRASFVGVPTGTTRADVEMHFWPLG--- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 ---------SPTEEPDEAPHRRYHLLPLSAR-----TPEALVRLASRHLA Mb0104|M.bovis_AF2122/97 ---------RQPSTPAWFLDSARGVHQFLG-----------RRRFVYPWV Rv0101|M.tuberculosis_H37Rv ---------RQPSTPAWFLDSARGVHQFLG-----------RRRFVYPWV MAV_3239|M.avium_104 ---------AERWTPDGSPAGIGGAVEFRTDVFDTATVEALTQRLRRVLA MMAR_3176|M.marinum_M ---------VDLPSPTKDPQPLAGTIEYATDLFDRDTIEKFATSYLHILD MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 GHDSIDASHYPLTWVASPGRRLWMKLEYRPDVVERDRAQGLLDRLRQVLL MAB_2258|M.abscessus_ATCC_1997 -------------------DRIGVQFVYSTELFDAATVEQMRDDYTALLR TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 YLEDDPDATIVDICAAAGAGRSHFEHR-------------AALVVDSRPR Mb0104|M.bovis_AF2122/97 AWLVQRGAAPGDVLVFTDDDTD------------------KTIDLLIACH Rv0101|M.tuberculosis_H37Rv AWLVQRGAAPGDVLVFTDDDTD------------------KTIDLLIACH MAV_3239|M.avium_104 AMTADPGRRLSSIDLLDPDEHARLDALGNRAALTRPQHPPTSIPAMFAAQ MMAR_3176|M.marinum_M IVTTNPQQQIDLVEIIDPVERQRLLVECN---DTATAIPETTIAELFAAQ MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 QVGTGVERPSAALTLPLPAEADHKRTR---DAATEHDLPHASVLDLLAER MAB_2258|M.abscessus_ATCC_1997 AALASPHLPIGHLPLGAG---------------------EALVVQSLAPM TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 ARRLLRAIHEERPAPGLVRGVCSDRPKT----------------AWLFGG Mb0104|M.bovis_AF2122/97 LAGCGYSVCDTADEISVRTNAITEHG------------------DGILVT Rv0101|M.tuberculosis_H37Rv LAGCGYSVCDTADEISVRTNAITEHG------------------DGILVT MAV_3239|M.avium_104 VARTPHAVALTANGRSVTYRRLEEHANQLAHQLIRYGAGPGRCVAVLLER MMAR_3176|M.marinum_M VARVPESAAVHDDLEMLTYRELDVRASDLARGLAARGAGPEAIVAVALPR MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 AVQSGDLTALVCGGEFVDYAELLARVNRLAWVLRSRGIGPEDTVALAVPR MAB_2258|M.abscessus_ATCC_1997 FRHAENSVAIVDAGVEITH--------------------------AHLRK TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 QGNQFPGMAREVFDHEPVFAQTLRRCGEVLDGLLPRPL------------ Mb0104|M.bovis_AF2122/97 VVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKT------------ Rv0101|M.tuberculosis_H37Rv VVDVAATQLAVVGHDELRKVVDERVTQVTHDALLATKT------------ MAV_3239|M.avium_104 SAEAVAAILGVLKAGAAYLPIDPSLPSARIEFMLTDAAPAAVLTSTEFHC MMAR_3176|M.marinum_M SARLVVALLAIAKTGAAYLPIDPNYPSERSAYILTDAAPQLLITDTSTAP MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 SIDAVVALFAVLRAGAAYLPLELDYPDERLAVMLGDAEPVRVLVTGATAQ MAB_2258|M.abscessus_ATCC_1997 TAAQLVAAMPGVRGGTVVLGFER--------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------L Mb0104|M.bovis_AF2122/97 -------------------------------------------------A Rv0101|M.tuberculosis_H37Rv -------------------------------------------------A MAV_3239|M.avium_104 RLQEY----------------DQTVIDVDDPSIREQPVTAPPAPAPDNIA MMAR_3176|M.marinum_M TLPDTGVAVLILDTTLDTSPDTTEVPDRGTEATPGYCYQDSLGPGPDNLA MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 RIARVASAP----------LTVLDAPDTCDELARARSDWDGYSPHPDQPA MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 EVIFDTGPEAEHNLRNTAFAQPALFAV----EMGMARLWRSWGVEP---- Mb0104|M.bovis_AF2122/97 YIMPTSGTTGQPKLVRISHGSLAVFCD----AISRAYGWGAHDTVL-QCA Rv0101|M.tuberculosis_H37Rv YIMPTSGTTGQPKLVRISHGSLAVFCD----AISRAYGWGAHDTVL-QCA MAV_3239|M.avium_104 YLIYTSGTTGVPKGVAVTHRNATQLFA----SLGAAGLPAAPGKVWGQCH MMAR_3176|M.marinum_M YILYTSGSTGHPKPVAITHRNVVALFT----GFGWWRGLTDT-DVWAWCH MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 YVIYTSGSTGKPKGVVTPHRGLTNMHLNHREAIFAPTIARAHGRRLKIAH MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 DVVLGHSVGQYAAACVAGVFGLDEGARLIAERGRLFANLPSGGRMLAVFA Mb0104|M.bovis_AF2122/97 PLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLVARETTIVDLP Rv0101|M.tuberculosis_H37Rv PLTSDISVEEIFGGAACGARLVRSAAMKTGDLAALVDDLVARETTIVDLP MAV_3239|M.avium_104 SLAFDFSVWEIFGALLNGGRVLVVPDDVVRSPEDLCALLIDEHVDVLSQT MMAR_3176|M.marinum_M SPAFDFSVWELWGALLHGAQAVVVPWEVVRSPRELWQLVVDKRITVLSQT MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TVSFSFDMSWEELLWLIEGHEVHICDEVLRRDATSLVRYCHDHRIDVINV MAB_2258|M.abscessus_ATCC_1997 -----------------GSDLVAAVVAAVSAGAGRLVWLPASLPAPYREH TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 DPDRVERCTAEHSRLSVAAY-NGANTVLSGPAPDLEQVHAELTAAGSRCD Mb0104|M.bovis_AF2122/97 TAVWQLLCADGDAIDAIGRS-RLRQIVIGGEAIRCSAVDKWLESAASQGI Rv0101|M.tuberculosis_H37Rv TAVWQLLCADGDAIDAIGRS-RLRQIVIGGEAIRCSAVDKWLESAASQGI MAV_3239|M.avium_104 PSAFDALQR----ADSARRL-NPQTVIFGGEALIPHRLGGWLDGHPAR-P MMAR_3176|M.marinum_M PSAFYELIRVQRELPASAESSALRMVVFGGEALDPSRLRGWYPGQGEQAP MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TPTYAALLFEEGLLEQAGHP--PVLVLLGGEAVSTTVWNRLRDSERWYGY MAB_2258|M.abscessus_ATCC_1997 SLRQLAPTAVVDDATVADAAATGIRAMGESETLNTDAAVGLLDSSLAELL TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 WLDTSHAFHSALVDPALDEFES------------------FAAQFEYRAP Mb0104|M.bovis_AF2122/97 SLLSSYGPTEATVVATFLP---IVC-----DQTTMDGALLRLGRPILP-- Rv0101|M.tuberculosis_H37Rv SLLSSYGPTEATVVATFLP---IVC-----DQTTMDGALLRLGRPILP-- MAV_3239|M.avium_104 RLINMYGITETTVHASFRE---IVDGDIDGNVSPIGMPLAHLGFFVLDGW MMAR_3176|M.marinum_M ALINMYGITETTVHTTYLELTSEDAEG---GVSPIGGPLGNVRVFVLDAG MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 NLYGPTEYTINTLGGGTDDS----------ATPTVGTPIWNTRAHILDNW MAB_2258|M.abscessus_ATCC_1997 VALLYSGRIDLKN-------------------------DAPASRAVLTAD TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 KLTLVCNRTGKVLTRQTRLDAPYWRR--------------HAREPVRFAD Mb0104|M.bovis_AF2122/97 --NTVFLAFGEVVIVGDLVADGYLGIDGDGFG--TVTAADGSRRRAFATG Rv0101|M.tuberculosis_H37Rv --NTVFLAFGEVVIVGDLVADGYLGIDGDGFG--TVTAADGSRRRAFATG MAV_3239|M.avium_104 LRPVPAGVTGELYIAGAGVAAGYLGRPGLTASRFVACPFGGAGERMYRTG MMAR_3176|M.marinum_M LCPVPVGVAGELYVAGAQVARGYRGRVGLTAQRFVACPFGPAGSRMYRSG MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LRPVPDGVPGELYIAGAGLARGYLGQPGLTASRFVANPFEPGR--MYRTG MAB_2258|M.abscessus_ATCC_1997 GRSAPPGVLGELCIG-------------------------RPGEGVLPTG TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 SAATLADLGCAVLMELGPQPVLIAAALRNWPETAPVPTAIASLRRDADAH Mb0104|M.bovis_AF2122/97 DRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVEL Rv0101|M.tuberculosis_H37Rv DRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAEDPAVSDVAVEL MAV_3239|M.avium_104 DLARWGTDGQLHYLGRADQQVKIRGYRIELGEIQSALAELDGVEQATVIA MMAR_3176|M.marinum_M DLVRWNSSGVLEFVGRADDQVKIRGFRIEPGEVEAVLAAHPRVAQAAVAA MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 DLVVRRADDNIDFLGRTDDQVKIRGYRVELGDIEAALVSHPGVSQAAVIA MAB_2258|M.abscessus_ATCC_1997 IQARMRRDSSVEIAHTVRGCVWDGNRWADLTTVEAVLIDHELVDDCAVLS TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 RCFTDALG--------------------VAYTTGHRLDFAGHLGRRRTLD Mb0104|M.bovis_AF2122/97 HSGSLG----------------------VWFKSQRTREGEQDAAAATRIR Rv0101|M.tuberculosis_H37Rv HSGSLG----------------------VWFKSQRTREGEQDAAAATRIR MAV_3239|M.avium_104 REDRPGDKRL------------------VGYVTGTADPAQLRTALAERLP MMAR_3176|M.marinum_M YSTSGGLEGISDKQLVGYIVAESVTDAGPEIASGAADEYAELAVEVRRWV MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 RPDTAGSSR-------------------LVAYVVPTTENPDVLDDLRMHL MAB_2258|M.abscessus_ATCC_1997 RRINSG---------------------TAELVAYVATSAPASTRRLAEIA TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 LPTYPFEHRAYWFPTTKVHTLPAGGGVESPAAESNTGDWLTGMSDEQRID Mb0104|M.bovis_AF2122/97 LVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQ Rv0101|M.tuberculosis_H37Rv LVLVSLGVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQ MAV_3239|M.avium_104 AYLVPA-----AVVAIDAMPLTPNGKLDTGALP-APDYHGADQYHAPASA MMAR_3176|M.marinum_M GERLPEYMVPAAVMVIDALPLTANGKLDRRGLP-APQFSGAAVYRGPRDE MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 TATLPAYMVPTAMATLTEIPLTDNGKLDTRALPDVAPIGRHGAGRAPQGA MAB_2258|M.abscessus_ATCC_1997 RTVLPPLLVPRAFVPVAALPVTPAGALDSAALARLPVIDDELVEQWSARL TH_4455|M.thermoresistible__bu ---------------------------MTLSSTDLAALTPE--------- Mvan_1000|M.vanbaalenii_PYR-1 RIIELTRTELGNALRVAPAEIDPTAEFMTIGMDSMIAMELRGRLQAALGT Mb0104|M.bovis_AF2122/97 RAAGLSQIWSRQLG----RAIGPDSSLLGEGIGSLDLIRILPETRRYLGW Rv0101|M.tuberculosis_H37Rv RAAGLSQIWSRQLG----RAIGPDSSLLGEGIGSLDLIRILPETRRYLGW MAV_3239|M.avium_104 VEQTLADIYAHVLDVRPPRLVGIDDSFFDLGGDSLSAMRLVAEVNSRLDV MMAR_3176|M.marinum_M REAVLAGLFAEVLG---VAQVGIDDRFFDLGGHSLSVTRLVARIRAELNV MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VEATLCSVFAEVLGLDGPDGLSVDDDFFDLGGHSLLTIRLISRIRSELGA MAB_2258|M.abscessus_ATCC_1997 PEATMVRAVP-----------DIDEAPSVLVGDPNPPAKQAPAAPGAQPG TH_4455|M.thermoresistible__bu ---------------QKRALLARLLKQRAEAS---------------ASV Mvan_1000|M.vanbaalenii_PYR-1 PVPASLFFENPTVSTLAEALHALWLDASSDPSRRESPIPRVPHGCTLPCD Mb0104|M.bovis_AF2122/97 RLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQR-------PAA Rv0101|M.tuberculosis_H37Rv RLSLLDLIGADTAANLADYAPTPDAPTGEDRFRPLVAAQR-------PAA MAV_3239|M.avium_104 HLGVRALFEAPTIRRLAARLGADGSAR-----APLVAAER-------PAV MMAR_3176|M.marinum_M EVPIRAVFNAPTVAELAEWISVHGGARVRAALVARERPAR---------- MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 ELTLGDVFNSRTVAALARHVTADEGDNRRPRLVAGPRPQH---------- MAB_2258|M.abscessus_ATCC_1997 GQEPSVLHGGPAVIPVVASLPGALTRAAREAATTELVFLDES-----GTE TH_4455|M.thermoresistible__bu HPLSYGQRSMWFLYQLAPGSPAYNISFAGRIRGPLDMGALHRAAQALVDR Mvan_1000|M.vanbaalenii_PYR-1 VPLSHAQEQLWFLNQLLPSSSAYNVAIRVDIRGALDHEVLQRSLEAVVDR Mb0104|M.bovis_AF2122/97 IPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGR Rv0101|M.tuberculosis_H37Rv IPLSFAQRRLWFLDQLQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGR MAV_3239|M.avium_104 VPLSFAQSRLWFIGQLHGPSPVHNMAIALQLHGRLDAAAFGAALADVVGR MMAR_3176|M.marinum_M LPLSYAQTRLWFLHKYEGPSATYNIPLAVRLTGEIDAVALCAAIVDVVAR MLBr_00243|M.leprae_Br4923 -MSKFTEKMFRNARESSKGIVTGEPHNPVRHTWGQVHERASRIAGGLAGV MUL_4648|M.ulcerans_Agy99 -MSRFTEKMFRNARETTKGMVTGEPHTPVRHTWGEVHERARQIAGGLAAA Mflv_1935|M.gilvum_PYR-GCK -MSRFTEKMYRSAHTTGRGMVTGEPYEPVRHTWSEVHERAKRIAGGLAAA MSMEG_0019|M.smegmatis_MC2_155 IPASPAQRRMLMLDRLGETGSAYNYPLVFRVRGALDVDALRDALTAVVDR MAB_2258|M.abscessus_ATCC_1997 RTLNYAEVLDSAQRVLGGLRAVGMAPGDLAIVHLSRNDDFVAAIWGCFLG : . TH_4455|M.thermoresistible__bu HAILRTTYAVRDGRPVQLVHPHWPVQIDQHDIGS---DDTEFDRWLRRES Mvan_1000|M.vanbaalenii_PYR-1 HEALRTVFQSRHGAPQAILTPSQPIKLAFEEIG----DEADIAAAAVREA Mb0104|M.bovis_AF2122/97 HESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAA Rv0101|M.tuberculosis_H37Rv HESLRTVFPAVDGVPRQLVIEARRADLGCDIVDATAWPADRLQRAIEEAA MAV_3239|M.avium_104 HESLRTLFPAHEGIPQQLVIEVDEADIGWQVIDASGWSPARLDDVIRDTA MMAR_3176|M.marinum_M HESLRTLFTESDGIPCQQVLAVEDVDVPVVVTEV---AAQGLAAAAIEAV MLBr_00243|M.leprae_Br4923 GVGHGDAVGVLVGVPVEIAPTAQGLWMR------------GASLTMLHQP MUL_4648|M.ulcerans_Agy99 GVGPGDAVGVLAGAPVEIAPTAQGLWIR------------GASLTMLHQP Mflv_1935|M.gilvum_PYR-GCK GVGLGDAVGVLAGFPVEIAPTAQGLWMR------------GASLTMLHQP MSMEG_0019|M.smegmatis_MC2_155 HEALRTVFDDRDGVYHQRILPRGTQPPLHVSDCP----EHELATRADALV MAB_2258|M.abscessus_ATCC_1997 GIVPVPVAPNVVGGTEKVAAAWHTLKQPLIVG--------EIPQPVAHQG * TH_4455|M.thermoresistible__bu NQPFDLETGPVFRLSVVRRASGEQLLVLVVHHIAVDFWSIDVILDELRRL Mvan_1000|M.vanbaalenii_PYR-1 SVPFDIGAGPLLRARLFGVGDQRHVLVVTMHHIVTDGWSFRVLLGDLGRT Mb0104|M.bovis_AF2122/97 RHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAA Rv0101|M.tuberculosis_H37Rv RHSFDLATEIPLRTWLFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAA MAV_3239|M.avium_104 RHTFDLAAEIPLRAVLLRCGDEEHLLVAVVHHIAADGWSLTPLVRDLARA MMAR_3176|M.marinum_M GYRLDLATEIPIRAELLRVSPTEHVLVVMIHHIAADGASLVPLARDVATA MLBr_00243|M.leprae_Br4923 TPRTDLAVWEEDTTTVIDMIEAKAVIISDPFMAVAP-----ILEARGVKV MUL_4648|M.ulcerans_Agy99 TPRTDLALWAEDTTTVVDMIEAKAVVISDPFMAAAP-----VLEERGIRV Mflv_1935|M.gilvum_PYR-GCK TPRTDLVMWAEDTMNVIGMIEAKAVIVSEPFLVAIP-----VLEEKGIKV MSMEG_0019|M.smegmatis_MC2_155 EHRFDLTGEIPLRVDVLRSGPEDHTVVMLLHHIAIDEWSDAVFLADLDAA MAB_2258|M.abscessus_ATCC_1997 ARVLLIGDLLTHEPDTDHHEPDPDEVALLLLTSGSTGQPKGVQLSHRNIL : : TH_4455|M.thermoresistible__bu YAAEHG--AERPEPCPQRYVDHAEHQIQMLESSE-----GERLWEYWRDR Mvan_1000|M.vanbaalenii_PYR-1 YQALERGAPAPLDDLPIQYADYARWQREQLTGPE-----FDAHIEFWKAD Mb0104|M.bovis_AF2122/97 YASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENA Rv0101|M.tuberculosis_H37Rv YASRCAGRAPDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENA MAV_3239|M.avium_104 YASRSAGRVPDWVPLPVQYVDYTLWQRAQFGDLDDPHSLIAGQLRYWESA MMAR_3176|M.marinum_M YTARLVGRAPDWAPLAVQYADYTLWQQEVLGSEDDPDSVLSHQFAYWRAE MLBr_00243|M.leprae_Br4923 VTVEQLLAADPVDPIETDEDDLALMQLT--------------------SG MUL_4648|M.ulcerans_Agy99 LTFEQLLASEPIDPVEVGEDELALMQLT--------------------SG Mflv_1935|M.gilvum_PYR-GCK LTITDLLASEPIEPIEVGEDDLALMQLT--------------------SG MSMEG_0019|M.smegmatis_MC2_155 YAAHRAGTAAPLPEPVVQYADHTLWQRDVLAQLG------DRQREFWRTA MAB_2258|M.abscessus_ATCC_1997 SRSASTAQSNAFGPEDISFNWMPLEHVGGIVMSHLQDVYVHCRQVHAATS . : TH_4455|M.thermoresistible__bu LAGDLPVIELPMDRPRRVAQTYRGAVHRFTIDRRLTADLKQTARRAGATP Mvan_1000|M.vanbaalenii_PYR-1 LAG-APPLELDTDRPRPKSPTFRGARIRFDLGRERADALRDLCRAGNVTL Mb0104|M.bovis_AF2122/97 LAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATS Rv0101|M.tuberculosis_H37Rv LAGMPERLRLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATS MAV_3239|M.avium_104 LAGMPERLELPTDRPYPVVADFRGASVAVEWPAQLQQQISRLAGAHNATS MMAR_3176|M.marinum_M LADAPKHIALPTDRPRPPQQSFRGEQIGLSIDAGLRARIEALARQSGTTT MLBr_00243|M.leprae_Br4923 STGSPKAVQITHRNVYSNVEAMFIG-VRYNVEKDVMISWLPCFHDMGMIG MUL_4648|M.ulcerans_Agy99 STGSPKAVQITHRNLFANLEAMYIS-AEYDAETDVMVSWLPLFHDMGMIG Mflv_1935|M.gilvum_PYR-GCK STGSPKAVQITHRNIYSNAEAMFIG-AQYDVEKDVMVSWLPCFHDMGMVG MSMEG_0019|M.smegmatis_MC2_155 LAGAPDELALPADRPRPARPTGAGGTLDVEITAETASALRRLAADKQVSM MAB_2258|M.abscessus_ATCC_1997 WVLADPLRWLTIADRYG-VTNTWAPNFAFGLIADRLAETPDAAQFDLTRL . : TH_4455|M.thermoresistible__bu YMTLLAAYIALLHRYSGQNDILIGSPFAGREQSGLDGVVGYFANPLVLRF Mvan_1000|M.vanbaalenii_PYR-1 SVPLLAAFATVLQRYSGQHDLVIGTLTANRGRLETENLIGLFVNALPIRI Mb0104|M.bovis_AF2122/97 FMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRV Rv0101|M.tuberculosis_H37Rv FMVVAAGLAVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRV MAV_3239|M.avium_104 FMVVQAALAVLLAKVSASSDVAVGFPIAGRRDPALDDVVGFFVNTLVLRV MMAR_3176|M.marinum_M SMVLQAALMVLLHKLGAGDDLTIGGPIAGRTDDTLNDLIGFFVNTWVLRV MLBr_00243|M.leprae_Br4923 FLTVPMYFGAELVKVTP---------------------IDFLRDTLLW-- MUL_4648|M.ulcerans_Agy99 FLTVPMYFAGELVKVTP---------------------MDFMRDTLLW-- Mflv_1935|M.gilvum_PYR-GCK FLTIPMYFGAELVKVTP---------------------MDFLRDTLLW-- MSMEG_0019|M.smegmatis_MC2_155 LMVLHAAVAVLIHRLGAGDDIVVGTPVAGRDDAALDDVVGLFVNTVVLRA MAB_2258|M.abscessus_ATCC_1997 RFILNGGEAIVPRVARRFLRMMEGFGLPRNAMRPSWGMSETSSGVVFSQN . : . TH_4455|M.thermoresistible__bu DVTGDTTFASLLGQTKQTVLDALAHQEFPFTLLVERLKPVRDVGHAPLFQ Mvan_1000|M.vanbaalenii_PYR-1 RLDGDPDMTELIDRIRGRMSEVLAHQDVPFDLIVTATAPDRDASRNPLFG Mb0104|M.bovis_AF2122/97 NLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQ Rv0101|M.tuberculosis_H37Rv NLAGDPSFAELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQ MAV_3239|M.avium_104 DVSGDPTVAELLARVRQRSLAAYEHQDVPFEVLVERLNPARSLAHHPLVQ MMAR_3176|M.marinum_M NTSGNPCFGELLEQVRDKALAAYENQDAPFERLVELLNPSRSTAHHPLFQ MLBr_00243|M.leprae_Br4923 --------AKLIDKYKGTVICGP---NFAYSLFTKRLRKQAKPGQFDLST MUL_4648|M.ulcerans_Agy99 --------AKLIDKYKGTMTAAP---NFAYSLFAKRLRKQAKPGQFDLSS Mflv_1935|M.gilvum_PYR-GCK --------AKLIDKYKGTMTAAP---NFAYALFAKRLRRQAKPGEFDLST MSMEG_0019|M.smegmatis_MC2_155 DLAGNPTFTELLDRVRTADLAAFAHQDLPFDHLVEELNPPRVAGRNPLFN MAB_2258|M.abscessus_ATCC_1997 FSIETTADTDEFTDLGGPIPGTRLRVADMDGSVVPEGQIGRVQISGPTVT . : .. TH_4455|M.thermoresistible__bu VSFAWEQHRRFRETRDSDTGIASGAELDLQTVHIGQGGAPNELMMLMGER Mvan_1000|M.vanbaalenii_PYR-1 VQLVVQP----------AAGAAELSSLGLDVAEIDTHTAKRDLTLTFFD- Mb0104|M.bovis_AF2122/97 VMLAWQDN---------PVGQLNLGDLQATPMPIDTRTARMDLVFSLAER Rv0101|M.tuberculosis_H37Rv VMLAWQDN---------PVGQLNLGDLQATPMPIDTRTARMDLVFSLAER MAV_3239|M.avium_104 VMLAWQNI---------EPTELSLGQVRVIPLPVDTRTARMDLAWSLAER MMAR_3176|M.marinum_M VSFAFQNN---------PLPAIDFPGLGIEVLSAPTHTAKFDLFINLVDL MLBr_00243|M.leprae_Br4923 LRIAMSGA--------EPVDPADVEDLIDAGRPFGFRPEAILPAYGMAET MUL_4648|M.ulcerans_Agy99 LRFALSGA--------EPVEPSDVEDLCEAGAPFGLRPQAILPAYGMAEI Mflv_1935|M.gilvum_PYR-GCK LRFALSGA--------EPVEPADVEDLLDAGKPFGLDPGAILPAYGMAET MSMEG_0019|M.smegmatis_MC2_155 LFVGYHLR---------SGTDSDMFGLPTEWTEPAVSAAMFDLGFTLVDH MAB_2258|M.abscessus_ATCC_1997 RGYYADPER--TAEAFATDGWFDTGDLGRIRAGVLTLTGRAKDIIIVNGV . : . TH_4455|M.thermoresistible__bu ------DGELVCALQYNTDLFDAATIERMAGHFVTMLSGIVAGPAAKVSE Mvan_1000|M.vanbaalenii_PYR-1 ------DELLAGHVEYATELFDEARIERLIAHFREVVDALVSDRRLRLSE Mb0104|M.bovis_AF2122/97 FSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSS Rv0101|M.tuberculosis_H37Rv FSEGSEPAGIGGAVEYRTDVFEAQAIDVLIERLRKVLVAVAAAPERTVSS MAV_3239|M.avium_104 WTPDGSPAGIGGAVEFRTDVFDTATVEALTQRLRRVLAAMTADPGRRLSS MMAR_3176|M.marinum_M PSPTKDPQPLAGTIEYATDLFDRDTIEKFATSYLHILDIVTTNPQQRIDL MLBr_00243|M.leprae_Br4923 -------TLAVSFSPVGEGLLVDEVDADLLAALRRAVPATKGNIRRLVSL MUL_4648|M.ulcerans_Agy99 -------TLAVAFSECGAGLVVDEVDADLMAALRRAVPAAKGNTRRLASL Mflv_1935|M.gilvum_PYR-GCK -------TLAVSFSPCGAGLTVDEVDADLLAALRRAVPASKGHTKRLAEL MSMEG_0019|M.smegmatis_MC2_155 GG----DESASITAEYAADLFDASTVHTLARRLVALLDHVVADAETRIGA MAB_2258|M.abscessus_ATCC_1997 NYSCHAIESAVEESPLVISSYVAAIAVRLPGSDTDGLAIVFS-AQAAVAE : : TH_4455|M.thermoresistible__bu LPLLTDAECRRLAQWN---RTEVDFGAPECLHDLVTTAARRDPAAVALSS Mvan_1000|M.vanbaalenii_PYR-1 VTMLTESERAHYAVTR---SPLAPTAR--SVPELFEMTADRTPDAVAVRA Mb0104|M.bovis_AF2122/97 IDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCC Rv0101|M.tuberculosis_H37Rv IDALDGTERARLDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCC MAV_3239|M.avium_104 IDLLDPAEHARLDALGNRAVLTRPQHPPTSIPEVFAAHVARTPHAVAVTC MMAR_3176|M.marinum_M IEIIDPAERQHLLVECN---DTATAIPETTIAELFSAQATRTPDAPALHD MLBr_00243|M.leprae_Br4923 GPLLDGLEVRIVDEDGN-------------------VLPSRGVGVIELRG MUL_4648|M.ulcerans_Agy99 GPLLQGIEARIVDADGN-------------------VLPSRGVGVIELRG Mflv_1935|M.gilvum_PYR-GCK GPLLTDLEARVIDDHGN-------------------LMPPRGVGVIELRG MSMEG_0019|M.smegmatis_MC2_155 LDLLAPGEHDTLVVEHN---ATEHPLEPITLGALVSRQATSTPHATALRY MAB_2258|M.abscessus_ATCC_1997 EDVLADVRARVLAVGPN--------------PDLLIPVPPESIPKTDIGK : . : TH_4455|M.thermoresistible__bu ADGELTYGELDRRSETLALRLQRLSVGPDTIVPVLLDRSADLVVAWLG-- Mvan_1000|M.vanbaalenii_PYR-1 PDRSLTYRELDAAANRLARRLRALGVGAGAAVGLRVGRSAAMAVGMLG-- Mb0104|M.bovis_AF2122/97 GDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVA-- Rv0101|M.tuberculosis_H37Rv GDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVA-- MAV_3239|M.avium_104 GRRSWTYRELDSSANRLAHLLIHHGAGPGDCVALLLERSAEAVAAILG-- MMAR_3176|M.marinum_M DHQTLTYRELAARVNRLARFLIAAGVGPEAVVGLAIRRSIELVVGMYA-- MLBr_00243|M.leprae_Br4923 ESLTPGYITMGG----FISAQDEHGWYDTGDLGYQMENGHIVVCGRVKDV MUL_4648|M.ulcerans_Agy99 ESVTPGYLTMGG----FIPAQDQLGWYDTGDLGYQMENGHVVVCGRVKDV Mflv_1935|M.gilvum_PYR-GCK ECVTPGYMTMGG----FIPAQDEHGWYDTGDLGYITEEGNVVVCGRVKDV MSMEG_0019|M.smegmatis_MC2_155 EESELSYRDLDGWSDRLAAHLSARGAAPGTVVGVSLPRSVELVVALVA-- MAB_2258|M.abscessus_ATCC_1997 IQRNLLRQQFAEGKFADIVRRVRTSGAPTDTIPNWFFRPLWHRRDRLRPS : . : . TH_4455|M.thermoresistible__bu VLKAGGAFMPIDPAQPVHRIAAIL-------------------------- Mvan_1000|M.vanbaalenii_PYR-1 ILKAGGVYVPVDPTYPQDRIEHMLGEAGVALLLDERDVDGAEAGLCS--- Mb0104|M.bovis_AF2122/97 VLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPII Rv0101|M.tuberculosis_H37Rv VLKTGAAYLPIDPANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPII MAV_3239|M.avium_104 VLKAGAAYLPIDPSLPSARIEFMLTDAAPAAVLTSTEFHCRLQEYDQTVI MMAR_3176|M.marinum_M VVQAGATFVPIDPNQPSQRNGYVIKTADPVCVLTTSGDRFDAAVGARVIE MLBr_00243|M.leprae_Br4923 IIMAGRNVYPTDIERAAGRVDGVR-------------------------- MUL_4648|M.ulcerans_Agy99 IIMAGRNIYPTDIERAAGRVEGVR-------------------------- Mflv_1935|M.gilvum_PYR-GCK IIMAGRNIYPTDIERAAGRVEGVR-------------------------- MSMEG_0019|M.smegmatis_MC2_155 VAKSGAAFLPLDPEYPRERLEYMVSDARPITVLDDPDAVRRSRGE----- MAB_2258|M.abscessus_ATCC_1997 VPVDGAVLLLGDSGALGSLLADRLRAQG---------------------- : * * TH_4455|M.thermoresistible__bu ----------------------------------SGASDAP--VCVTHRR Mvan_1000|M.vanbaalenii_PYR-1 ---------------AERLENLAAADDLAYIMYTSGSTGRPKGVAVTHGS Mb0104|M.bovis_AF2122/97 DVVD-AL-----AAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRN Rv0101|M.tuberculosis_H37Rv DVVD-AL-----AAYPGTPPPMPAAVNLAYILYTSGTTGEPKGVGITHRN MAV_3239|M.avium_104 DVDDPSI-----REQPVTAPPAPAPDNIAYLIYTSGTTGVPKGVAVTHRN MMAR_3176|M.marinum_M IDQVDVSGFSADPITDADRVRSLRPDNTAYVMFTSGSTGQPKGVAVSHAA MLBr_00243|M.leprae_Br4923 -------------------------------------PGCAVAVRLDAGH MUL_4648|M.ulcerans_Agy99 -------------------------------------PGCAVAVRLDAGH Mflv_1935|M.gilvum_PYR-GCK -------------------------------------PGCAVAVRLDAGH MSMEG_0019|M.smegmatis_MC2_155 ---------------PDGELPRIDPAAWAYVLYTSGSTGRPKGVAVAHAG MAB_2258|M.abscessus_ATCC_1997 ----------------------------AHVVCAAVADVAERSDRPAGVG TH_4455|M.thermoresistible__bu HTDLLREFR-------GEQVFLDVG------------------------S Mvan_1000|M.vanbaalenii_PYR-1 VVEYAETLGRE-LGITGEDVYLETASISFSSSIRQMLVPFAVGAEVVIAT Mb0104|M.bovis_AF2122/97 VTRLFASLPAR---LSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVP Rv0101|M.tuberculosis_H37Rv VTRLFASLPAR---LSAAQVWSQCHSYGFDASAWEIWGALLGGGRLVIVP MAV_3239|M.avium_104 ATQLFASLGAAGLPAAPGKVWGQCHSLAFDFSVWEIFGALLNGGRVLVVP MMAR_3176|M.marinum_M IVNHVLWMRAH-YAVGPKDVYLQKTAATFDVSLWGYFVPLISGAQIMLAA MLBr_00243|M.leprae_Br4923 SRETFAVAVES--------------------------------------- MUL_4648|M.ulcerans_Agy99 SRETFAVAVES--------------------------------------- Mflv_1935|M.gilvum_PYR-GCK SRETFAVAVES--------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 IVNRIACLQHAYP-LGTDDRMLVKTPISFDTSVWEVFWPLSVGATLVVAR MAB_2258|M.abscessus_ATCC_1997 AVQTVVYLAAP--------------------------------------- TH_4455|M.thermoresistible__bu PVPPRLP--------APPAPPATTWRMSSTPRVPPG-------PRRARST Mvan_1000|M.vanbaalenii_PYR-1 TEERRDP--------AALLRRIGESAVTVADLVPTV-------VRRVIDV Mb0104|M.bovis_AF2122/97 ESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQG-------LESVALV Rv0101|M.tuberculosis_H37Rv ESVAASPNDFHGLLVAEHVSVLTQTPAAVAMLPTQG-------LESVALV MAV_3239|M.avium_104 DDVVRSPKDLHALLVAERVDMLTQTPSEVGVLSPDG-------LESTTLA MMAR_3176|M.marinum_M PNEQGNPQYLAKTIHSRGVTLTDFVPSMLSVFCASAPHDALVSLRDVFVI MLBr_00243|M.leprae_Br4923 -NAFEDT--------AEVRRIEHQVAHEVLKEVDVR-------PRNVVVL MUL_4648|M.ulcerans_Agy99 -NAFEDP--------AEVRRIEHQVAHEVVAEVDVR-------PRNVVVL Mflv_1935|M.gilvum_PYR-GCK -NNWQDP--------VEVRRIEHQVAHEVVAEVDVR-------PRNVVVL MSMEG_0019|M.smegmatis_MC2_155 PGGHREPAYLAAMIAEQCVTAVDFVPSMLEVFLDEVAGTCASLTRVTVGG MAB_2258|M.abscessus_ATCC_1997 QEDDAKAKNHPELLAGSLLDVARIVRSVTNGRFNEP-------PPAVYVV . . TH_4455|M.thermoresistible__bu PTAASATGCCGCSR-------PIRSPPPTGCCNRHR-------------- Mvan_1000|M.vanbaalenii_PYR-1 VAAADAGQRTASRRNRLRLLLTASEPLRAGVVRAWREQLGGGASWINMYG Mb0104|M.bovis_AF2122/97 VAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGS------- Rv0101|M.tuberculosis_H37Rv VAGEACPAALVDRWAPGRVMLNAYGPTETTICAAISAPLRPGS------- MAV_3239|M.avium_104 VAGEACPVEVVDRWAPGRVMINVYGPTETTIVAAVSAPLTPGP------- MMAR_3176|M.marinum_M GEALPPTTAQAFTTVCDAALHNAYGPTEAVTTTTWRTSPSDVHS------ MLBr_00243|M.leprae_Br4923 GPGTIPKTPSGKLRRASSVTLVT--------------------------- MUL_4648|M.ulcerans_Agy99 GPGTIPKTPSGKLRRSNSLTLVT--------------------------- Mflv_1935|M.gilvum_PYR-GCK GPGSIPKTSSGKLRRSNSVSLVT--------------------------- MSMEG_0019|M.smegmatis_MC2_155 EALTTELAARFAEAFPGVPLHNLYGPTEAAVDVLGWTAD----------- MAB_2258|M.abscessus_ATCC_1997 GRGIERVANTDMADPELAPIPVLLRSAVAEMPGLRVRFIDLDPR------ TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 QTETTGIVSLHPVGEPDGDAQSIVPIGRPRANVGMYVLDRLMRPVPPGVG Mb0104|M.bovis_AF2122/97 ---------------------GMPPIGVPVSGAALFVLDSWLRPVPAGVA Rv0101|M.tuberculosis_H37Rv ---------------------GMPPIGVPVSGAALFVLDSWLRPVPAGVA MAV_3239|M.avium_104 ---------------------EAPPIGAPVPGTALRVLDAHLRPVPPGVV MMAR_3176|M.marinum_M -----------------------VPIGAPQWNCQVFVLDAGLCPVPVGVA MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 --------------------GGPVALGVPGWNVRAYVLDDYLNPVPAGAP MAB_2258|M.abscessus_ATCC_1997 ------------------------DLAAGADDIVGELGYATNDIEVAYRD TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 GALFIAGPALAREYVGDPTLTAQKYVPAPWN-PAERLYVSGDMVRLGWDG Mb0104|M.bovis_AF2122/97 GELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADG Rv0101|M.tuberculosis_H37Rv GELYIAGAGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADG MAV_3239|M.avium_104 GELYVAGAGVSTGYLGRPGLTASRFVACPFGGAGERMYRTGDLVRWGADG MMAR_3176|M.marinum_M GEAYIAGAQLAQGYRGRGGLTAERFVACPFGPAGSRMYRSGDLVRWNSSG MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 GELYLAGIQLADGYLHRGALTAARFVASPFDQGAR-MYRTGDVVRWRADG MAB_2258|M.abscessus_ATCC_1997 GVRWVKGLQRLPDDATLAAQIPSGAVHLISGGLGGLAYELARMLIERFDG TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 TIEYRGRADRQVKIRGLRVEPAEIDRVLLEHPGVREAVTVVREANADG-- Mb0104|M.bovis_AF2122/97 QLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGD-- Rv0101|M.tuberculosis_H37Rv QLEFLGRTDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGD-- MAV_3239|M.avium_104 QLQYLGRADEQVKIRGYRIELGEIQSALAALDGVDQAAVIAREDRPGD-- MMAR_3176|M.marinum_M VLEFVGRADDQVKIRGFRVEPGEIAAVLAAHPRVAQAAVSTHTTTTDTGG MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 QLEYLGRSDDQIKLRGVRIEPGEIETVLATHPAVSSVRVIARGG------ MAB_2258|M.abscessus_ATCC_1997 RVLLVGHRDPDERQLAAYRRLCDIAGGASVRLEVADVCDT---------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 ----AALVAYFTTG-DTPVPVGELRAHARRQLPDHMVPSAFTALEQLPLT Mb0104|M.bovis_AF2122/97 ----KRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLT Rv0101|M.tuberculosis_H37Rv ----KRLVGYATEIAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLT MAV_3239|M.avium_104 ----KRLVGYVT----GTADLAQLRTALAERLPGYMVPAAVLMLDALPLT MMAR_3176|M.marinum_M GIGEKQLVGYIVPDREVTLAREAPREAGLVQQWGQVWGGVYSGLTSQVPA MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 --RLMAYYVPAGVEASAGELRDELREHAAAALPSHMVPSGFVALTEFPLT MAB_2258|M.abscessus_ATCC_1997 --------GRVWDAVTAAENAWGIQLAGIWHLAGIYREQSLAAMTDAEFA TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 PNGKLDRTALPEVT-ITRDQEIEYVPPRSGVEQSLAEIWSDTLQLEQ-IG Mb0104|M.bovis_AF2122/97 VNGKLDHRALPAP---EYGDTNGYRAPAGPVEKTVAGIFARVLGLER-VG Rv0101|M.tuberculosis_H37Rv VNGKLDHRALPAP---EYGDTNGYRAPAGPVEKTVAGIFARVLGLER-VG MAV_3239|M.avium_104 PSGKLDTGALPAP---DYQGPEGYLAPAGAVEEILAWLYAQVLGLPRRVG MMAR_3176|M.marinum_M VLGEDFRSWVSSYTGAPIPLEQMGEWRAAAVERIVGLSPGRVLEIGVGTG MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 PSGKLDRRALPEFAGATAGVPG--RAPTTERQHRLCELFSDVLGLEVTG- MAB_2258|M.abscessus_ATCC_1997 DIARAKVGGARALHAIALHRPGIRFVSFSSVNGFFGGSTVGGYSVANAYL TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 AGDNFFELGGHSLLAAQVRSRIHQLLGVELPLEALFEDQTLSDLAHRIEG Mb0104|M.bovis_AF2122/97 VDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLLGR Rv0101|M.tuberculosis_H37Rv VDDSFFELGGDSLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLLGR MAV_3239|M.avium_104 VQESFFDLGGDSLSAMRLVAAIYNALDIHLPVRAVFEAPSVRSLSQRLNA MMAR_3176|M.marinum_M LLLAQLAPDCVEYWGTDFSASTIEMLQAAVASRPWGDRVRLRVQPADSAE MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 IDDDFFVLGGHSLLLVRLAAALRREFSVDVPVADLMVSPTVADIDQRLDA MAB_2258|M.abscessus_ATCC_1997 DAFALYQRRTCGIAAHSVAWTMWDRVGMSAQVEHVEGTRARG-------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 DTGVDTSEAPLLRPVARTGPPPLSYAQELMWRNECDDPGSPAHWIDVS-I Mb0104|M.bovis_AF2122/97 DARPTS--DPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNLPG--- Rv0101|M.tuberculosis_H37Rv DARPTS--DPRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNLPG--- MAV_3239|M.avium_104 DPAVAQGLRADFASVHGRDATEVYASDLTLDKFIDAATLSAAPALPG--- MMAR_3176|M.marinum_M GLPAGHFDVVVLNSVIQYFPSAGYLLDVLAVAMRLLAPGGALFIGDVRNL MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 AGSSVDSLAPVLPFRASGTDAPLFCVHPASG------------------- MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 RITGPLDPDLVVRGIQAATHRHELLRTVFRPSGASAAQVILDSYTPEVPI Mb0104|M.bovis_AF2122/97 --PSPELRTVLLTGATGFLGRYLVLELLRRLD-VDGRLICLVRAESDE-- Rv0101|M.tuberculosis_H37Rv --PSPELRTVLLTGATGFLGRYLVLELLRRLD-VDGRLICLVRAESDE-- MAV_3239|M.avium_104 --PGAEVRTVLLTGATGFLGRYLVLQWLERLELADGKLICLVRAASDD-- MMAR_3176|M.marinum_M GLLRAFTTKVLCTGTAGANDAAAVMRERVRREMLAEQELLLAPEFFSALP MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 -------------------------------------------------- MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 FDGAAALQHDVWPDQPDLATCPPLRAELCRIDDGNHILRLRVHRILADGY Mb0104|M.bovis_AF2122/97 -DARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWR Rv0101|M.tuberculosis_H37Rv -DARRRLEKTFDSGDPELLRHFKELAADRLEVVAGDKSEPDLGLDQPMWR MAV_3239|M.avium_104 -DARRRLERTFDSGDPALLRYFHELAADHLEVIAGDKGRANLGLDDRTWQ MMAR_3176|M.marinum_M QYLPDIAAVDIQLKRMQAVNELSCYRYEVVLRKGPVGVRSLAGLSALPWQ MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 -----------------LSWQFAGLKRHLPRQIPIYGLQSPLFTGTPLPE MAB_2258|M.abscessus_ATCC_1997 --------------------------YRVVGRVAALNSLLVALAHDEPHV TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 TMRLLLSEIGGLVASSAGLPDFPLLDGDLHYADYAIWERSWLTGAALQRR Mb0104|M.bovis_AF2122/97 RLAETVDLIVDSAAMVN-AFPYHELFGPNVAGTAELIRIALTTKLKPFTY Rv0101|M.tuberculosis_H37Rv RLAETVDLIVDSAAMVN-AFPYHELFGPNVAGTAELIRIALTTKLKPFTY MAV_3239|M.avium_104 RLADTVDLIVDAAAVVNGVLPYQELFGPNVAGTAELIRLALSTRLKPYSY MMAR_3176|M.marinum_M RFGGPAALGEYLQEHRPAGLRVSGIPHEAVWPDVAMAHALAQAGDRVLVS MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 SIAELTARYADTIVAVAPSGPVRLLGWSFGGSMALLIAQELSRRGREVTF MAB_2258|M.abscessus_ATCC_1997 LVGLDDTKPAIRARLSGVAPAGQVLVADLAEAVPGFADMPLRDKYDAIVP TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 IDHFRREFAVGELPPALPTDHPRTGRSRRAAGQLDFEFPAEVAAAARALA Mb0104|M.bovis_AF2122/97 VSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWAGGYGTSKWAGEVLLR Rv0101|M.tuberculosis_H37Rv VSTADVGAAIEPSAFTEDADIRVISPTRTVDGGWAGGYGTSKWAGEVLLR MAV_3239|M.avium_104 VSTANVGDQIEPSAFTEDADIRVAGPIRTIDGGYGNGYGNSKWAGEVLLR MMAR_3176|M.marinum_M QIGADPSPSDAVLPHHLHQLGREAGYSVAVTFSSTPGLMDVLLVDSLDAQ MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VGMLDARTDTADPNAGFDPEAVLAGLLREMGFGVDP-QARMTVADAVALV MAB_2258|M.abscessus_ATCC_1997 TRVQSAGVARTFVAARDETERRVSGIWRRVLGSDHFGVTDSFFDIGGNSV TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 VREHASLYTVLLAGFAAALGGYAGRRTVVLGSPVTRRNDPVTQLMLGP-- Mb0104|M.bovis_AF2122/97 EANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATGIAPRS Rv0101|M.tuberculosis_H37Rv EANDLCALPVAVFRCGMILADTSYAGQLNMSDWVTRMVLSLMATGIAPRS MAV_3239|M.avium_104 EAHDLCGLPVSVFRCDMILADTSYAGQLNLPDMFTRLLFSVVASGVAPRS MMAR_3176|M.marinum_M PLPALSDLYLPGAPIGSLAGYVNDPSAIELANEVRRWVGERLPEYMVPAA MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 RDTDDAITVLDDEQIALVIENYVAAERLTADADYGRYDG----------- MAB_2258|M.abscessus_ATCC_1997 LLALAQRLVQEEFGCQIALVDLFRYPTVSSLAVY---------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -FMNTVP---------------------------LRIDLPEGGGLAAMVQ Mb0104|M.bovis_AF2122/97 FYEPDSE---------------------------GNRQRAHFDGLPVTFV Rv0101|M.tuberculosis_H37Rv FYEPDSE---------------------------GNRQRAHFDGLPVTFV MAV_3239|M.avium_104 FYRLDAH---------------------------GNRQRAHFDALPVEFV MMAR_3176|M.marinum_M VMVVEGLPLTANGKLDRRALPAPQFTSTAAYRGPRDQREAVLAGLFAEVL MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 -------------------------------------DVFFVDATILEMD MAB_2258|M.abscessus_ATCC_1997 ------------------------------------LSSREFASDPSDPE TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 NMKTTVLGALSHQDAPSQHVIAALAAEHGPSAAAIGETVFLMDDPVPGEF Mb0104|M.bovis_AF2122/97 AEAIAVLGARVAGSSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRR Rv0101|M.tuberculosis_H37Rv AEAIAVLGARVAGSSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGYPIRR MAV_3239|M.avium_104 AEAIATLGAQVGRDAGTGFATYHVMNPHDDGIGLDEYVDWLIDAGYPIER MMAR_3176|M.marinum_M GVAQVGIDDRFFDLGGHSLSVTRLVARIRAELNVEVPIPAVFNAPTVAEL MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 LAGVASRGWHDHVGGRLKVAELDCRHSELMDAEVLERLGPLIAAELRGGD MAB_2258|M.abscessus_ATCC_1997 PVAVADAGVGSGRARIRQEARRRRRAR----------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 AAGGFRLTRVPPERVIARRELTAAMSTRNRQITGTLTYDSTLFDHPSIEC Mb0104|M.bovis_AF2122/97 IDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPLKPTRGCSA Rv0101|M.tuberculosis_H37Rv IDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPLKPTRGCSA MAV_3239|M.avium_104 VDDFDQWLHRMETALHALSERQRHQSVLQLLALRNARHVPPADPARGCLG MMAR_3176|M.marinum_M AEWLSKGCESEFVDPFAMVLPIRLSGTRPPIWCPSAAFGLSWSYRGLLDH MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 VASG---------------------------------------------- MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 IVAGFIGAVSALHVDCA--------------------------------- Mb0104|M.bovis_AF2122/97 PTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL------ Rv0101|M.tuberculosis_H37Rv PTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL------ MAV_3239|M.avium_104 PTERFRAAVQEAKIGADN---DIPHITAPVIVKYVTDLQLLGLL------ MMAR_3176|M.marinum_M VDDRPIYGLQAWNFYHTAEFTASVRTMVNDYLERILDIQKEGPFFLLGWS MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 -------------------------------------------------- MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M FGGVVAHAIAAELQNRGHEVALLALIASAPANENTRVALSESEVASESGF MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 -------------------------------------------------- MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M HSALEAWAKERDENISVDSPEYKLFAETLAVMTKNTIEILNDFVSPIYEG MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 -------------------------------------------------- MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu -------------------------------------------------- Mvan_1000|M.vanbaalenii_PYR-1 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MMAR_3176|M.marinum_M PAVLFIPTIDEKWSREQYLEEWSPHLKGNVSAHYIEGEHAGMDLPGPMAM MLBr_00243|M.leprae_Br4923 -------------------------------------------------- MUL_4648|M.ulcerans_Agy99 -------------------------------------------------- Mflv_1935|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0019|M.smegmatis_MC2_155 -------------------------------------------------- MAB_2258|M.abscessus_ATCC_1997 -------------------------------------------------- TH_4455|M.thermoresistible__bu ----------- Mvan_1000|M.vanbaalenii_PYR-1 ----------- Mb0104|M.bovis_AF2122/97 ----------- Rv0101|M.tuberculosis_H37Rv ----------- MAV_3239|M.avium_104 ----------- MMAR_3176|M.marinum_M IGRILDQMLKA MLBr_00243|M.leprae_Br4923 ----------- MUL_4648|M.ulcerans_Agy99 ----------- Mflv_1935|M.gilvum_PYR-GCK ----------- MSMEG_0019|M.smegmatis_MC2_155 ----------- MAB_2258|M.abscessus_ATCC_1997 -----------