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APMRYGIVLTTGDAADVAQLATLAEEAGWDAIFGWEPVWGVDAWVALTAAAMRTSRIKLGTMLTPLSRRK PWDLASTTATLDRLSGGRVILSVGMGALHDNWLAFERDQGRRTRAELLDEGLDVLFGLWEGQPFSYEGKH YQVTPTAHLVPDPPVQAPRITTWCVGLLGSAKSMSRAARCDGLLPNITTADGRFDFNPPLDRWADAAREI HSLRSELGYGDGYDVVYEATTDWSNLDATREKIATLHDGGYTWYLDSDWHTEHDDPLAALRARVEIGPPR *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2114c | - | - | 100% (281) | luciferase-like |
| M. abscessus ATCC 19977 | MAB_4277 | - | 9e-18 | 35.87% (184) | luciferase-like monooxygenase superfamily protein |
| M. abscessus ATCC 19977 | MAB_0858 | - | 2e-15 | 30.16% (189) | luciferase-like monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0978c | - | 3e-13 | 32.07% (237) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_1696 | - | 2e-18 | 30.56% (216) | luciferase family protein |
| M. tuberculosis H37Rv | Rv0953c | - | 4e-13 | 32.07% (237) | oxidoreductase |
| M. leprae Br4923 | MLBr_00348 | - | 3e-13 | 36.03% (136) | putative coenzyme F420-dependent oxidoreductase |
| M. marinum M | MMAR_4673 | - | 8e-20 | 31.78% (214) | hypothetical protein MMAR_4673 |
| M. avium 104 | MAV_0986 | - | 2e-18 | 31.34% (217) | hypothetical protein MAV_0986 |
| M. smegmatis MC2 155 | MSMEG_5715 | - | 9e-18 | 31.55% (187) | hypothetical protein MSMEG_5715 |
| M. thermoresistible (build 8) | TH_4607 | - | 4e-19 | 32.26% (186) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0292 | - | 4e-19 | 33.16% (190) | hypothetical protein MUL_0292 |
| M. vanbaalenii PYR-1 | Mvan_5062 | - | 5e-18 | 30.95% (210) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0978c|M.bovis_AF2122/97 ---------------MHYGLVLFTSDRGITPAAAARLAESHGFRTFYVPE
Rv0953c|M.tuberculosis_H37Rv ---------------MHYGLVLFTSDRGITPAAAARLAESHGFRTFYVPE
MSMEG_5715|M.smegmatis_MC2_155 ---------------MRFGLFIPQGWR-LDLVDIPTDRHWSVMRDLAAYA
TH_4607|M.thermoresistible__bu ---------------MRFGLFIPQGWR-LDLVDIPPERHWQVMRDLAVYA
Mflv_1696|M.gilvum_PYR-GCK ---------------MRFGLFIPQGWR-LDLVGIDPREQWRVMSDLATYV
Mvan_5062|M.vanbaalenii_PYR-1 ---------------MRFGIFVPQGWR-LDLVGIAPRDQWQVMRDLASYV
MMAR_4673|M.marinum_M ---------------MRFGLFIPQGWR-MDLVGIAPEQHWAVMRDLATYA
MUL_0292|M.ulcerans_Agy99 ----------------------------MDLVGIAPEQHWAVMRDLATYA
MAV_0986|M.avium_104 MKTVAVRPVRLESRGMRFGLFIPQGWR-MDLVGIEPDEHWAVMRDLAQRA
MAB_2114c|M.abscessus_ATCC_199 ------------MAPMRYGIVLTTGDA-ADVAQLATLAEEAGWDAIFG--
MLBr_00348|M.leprae_Br4923 -------------------MVERANAMKLGLQLGYWAAQPPGNAAELVAA
.
Mb0978c|M.bovis_AF2122/97 HTHIPVKRQAAHPTTGDASLPDDRYMRTLDPWVSLGAASAVTSRIRLATA
Rv0953c|M.tuberculosis_H37Rv HTHIPVKRQAAHPTTGDASLPDDRYMRTLDPWVSLGAASAVTSRIRLATA
MSMEG_5715|M.smegmatis_MC2_155 DGSQAWDSLWVYDHFHTVPVPTG--EATHEAWTLMAAYAATTSRIKLGQM
TH_4607|M.thermoresistible__bu DQS-AWDSIWVYDHFHTVPMPTH--EATHEAWSLMAAYAASTRSIKLGQM
Mflv_1696|M.gilvum_PYR-GCK DAGDAWDSLWVYDHFHTVPVPTD--EATHEAWSLMSAYAATTSRVKLGQM
Mvan_5062|M.vanbaalenii_PYR-1 DEGGVWDSLWVYDHFHTVPVPTA--EATHEAWSLMSAYAATTSRIKLGQM
MMAR_4673|M.marinum_M DASA-WDSLWVYDHFHTVPLPSD--EATHEAWSLMAAYAAVTSRIKLGQM
MUL_0292|M.ulcerans_Agy99 DASA-WDSLWVYDHFHTVPLPSD--EATHEAWSLMAAYAAVTSRIKLGQM
MAV_0986|M.avium_104 DRDVGWDSLWVYDHFHTVPVPTG--EATHEAWSLMAAYAAVTSRIKLGQM
MAB_2114c|M.abscessus_ATCC_199 -----WEPVWG-----------------VDAWVALTAAAMRTSRIKLGTM
MLBr_00348|M.leprae_Br4923 AEGAGFDAVFTGEAWG------------SDAYTPLAWWGSSTQRVRLGTS
. :.: : . * ::*.
Mb0978c|M.bovis_AF2122/97 VALPVEHDPITLAKSIATLDHLSHGRVSVGVGFGWNTDELVDHG---VPP
Rv0953c|M.tuberculosis_H37Rv VALPVEHDPITLAKSIATLDHLSHGRVSVGVGFGWNTDELVDHG---VPP
MSMEG_5715|M.smegmatis_MC2_155 CTAMSYRNPVYLAKVAATTDVISGGRVQMGIGGGWYEHEWRAYGYGFPSA
TH_4607|M.thermoresistible__bu CTAMSFRNPVYLAKVAATVDVISGGRVQMGIGAGWYEHEWRAYGYGFPPA
Mflv_1696|M.gilvum_PYR-GCK CTAMSYRNPAYLAKVAATADVISGGRIQMGIGGGWYEHEWRAYGYGFPSA
Mvan_5062|M.vanbaalenii_PYR-1 CTAMSYRNPVYLAKVAATADIISGGRIQMGIGGGWYEHEWRAYGYGFPSA
MMAR_4673|M.marinum_M CTAMSYRNPVYLAKVAATTDIISGGRIQMGIGGGWYEHEWRAYGYGFPSA
MUL_0292|M.ulcerans_Agy99 CTAMSYRNPVYLAKVAATADIISGGRIQMGIGGGWYEHEWRAYGYGFPSA
MAV_0986|M.avium_104 CTAMSYRNPVYLAKVAATADIISGGRIQMGIGAGWYEHEWRAYGYGFPSA
MAB_2114c|M.abscessus_ATCC_199 LTPLSRRKPWDLASTTATLDRLSGGRVILSVGMGALHDNWLAFERD-QGR
MLBr_00348|M.leprae_Br4923 VVQLSARTPTACAMAALTLDHLSGGRHILGLGVSGPQVVEGWYGQPFPKP
. : * * * * :* ** :.:* . .
Mb0978c|M.bovis_AF2122/97 GRRRTMLREYLEAMRALWT-QEEACYDGEFVKFGP----------SWAWP
Rv0953c|M.tuberculosis_H37Rv GRRRTMLREYLEAMRALWT-QEEACYDGEFVKFGP----------SWAWP
MSMEG_5715|M.smegmatis_MC2_155 GERLGRLDEGVQIMRDAWR-DGRVSFDGKHYQADG----------AIVSP
TH_4607|M.thermoresistible__bu KVRLGRLDEGVQIMHDAWL-NGIVSFDGEHYQVDG----------AIVEP
Mflv_1696|M.gilvum_PYR-GCK GTRLARLDEGVQIMRDAWR-DGVVSFDGKHYQVDG----------AIVAP
Mvan_5062|M.vanbaalenii_PYR-1 GVRLARLDEGVQIMRDAWR-DGTVTFDGKHYQADG----------AIVAP
MMAR_4673|M.marinum_M GTRLGRLDEGVQIMRDAWR-DGKVSFDGKHYQVDG----------AIVAP
MUL_0292|M.ulcerans_Agy99 GVRLGRLDEGVQIMRDAWR-DGKVSFDGKHYQVDG----------AIVAP
MAV_0986|M.avium_104 GVRLGRLDEGVQIMRDAWR-DGKVSFNGRHYQVDG----------AIVAP
MAB_2114c|M.abscessus_ATCC_199 RTRAELLDEGLDVLFGLWE-GQPFSYEGKHYQVTPT--------AHLVPD
MLBr_00348|M.leprae_Br4923 LSR---TREYIDIVRQVWAREAPVVSDGQHYPLPLTGAGATGLGKALKPI
* * :: : * :*..
Mb0978c|M.bovis_AF2122/97 KPVQP-HIPVLVGAAGTEKNFKWIARSADGWITTPRDVDIDEPVKLLQDI
Rv0953c|M.tuberculosis_H37Rv KPVQP-HIPVLVGAAGTEKNFKWIARSADGWITTPRDVDIDEPVKLLQDI
MSMEG_5715|M.smegmatis_MC2_155 TPLQEDGIPLWIAGGGEKVTLKIAAKYAQYTNFTSEPEAFRRKSQILAEH
TH_4607|M.thermoresistible__bu RPLQDERIPLWIAGGGEKVTLRIAAKYADYTNYTCDPEGFERKSEILAEH
Mflv_1696|M.gilvum_PYR-GCK RPLQDGGLPLWIAGGGEKVTLRIAAKYAQYTNFTSEPDGFEHKSRVLAEH
Mvan_5062|M.vanbaalenii_PYR-1 RPLQQAGIPLWIAGGGEKVTLRIAAKYAQYTNFTSEPEGFAHKSQVLAEH
MMAR_4673|M.marinum_M KPLQNNGIPLWVAGGGEKVTLRIAAQYAQYTNFTPQPEQFAHKSQVLAEH
MUL_0292|M.ulcerans_Agy99 KPLQNNGIPLWVAGGGEKVTLRIAAQYAQYTNFTPQPEQFAHKSQVLAEH
MAV_0986|M.avium_104 KPLQDNGIPLWIAGGGEKVTLRIAAEYAQYTNFTPESAAFAHKSEVLAAH
MAB_2114c|M.abscessus_ATCC_199 PPVQAPRITTWCVGLLGSAKSMSRAARCDGLLPNITTADGRFDFNPPLDR
MLBr_00348|M.leprae_Br4923 THPLRADIPIMLGAEGPKNVALAAEICDGWLPIFFSPRMADMYNEWLDEG
:. . . .
Mb0978c|M.bovis_AF2122/97 WAAAGRDG-----------------LPQIVALDVKPVP------------
Rv0953c|M.tuberculosis_H37Rv WAAAGRDG-----------------LPQIVALDVKPVP------------
MSMEG_5715|M.smegmatis_MC2_155 CRTVGTDF-----------------DAIVRSANFNAVIGESEKDVKERIE
TH_4607|M.thermoresistible__bu CHDVGTDF-----------------EAIVRSANFNAVLGETESEVADRLQ
Mflv_1696|M.gilvum_PYR-GCK CKDVGTDF-----------------DAIVRSANINVVVGTSEADVEDRLA
Mvan_5062|M.vanbaalenii_PYR-1 CRDVGTDF-----------------DKIVRSANINAVVGSSESDVKDRLA
MMAR_4673|M.marinum_M CRKLGTEF-----------------DAIVRSANFTAVLGTSEADVKDRMG
MUL_0292|M.ulcerans_Agy99 CRKLGTEF-----------------DAIVRSANFTAVLGTAEADVKDRLG
MAV_0986|M.avium_104 CRDVGTDF-----------------DAIVRSVNVNAVVGASRADVDDRLR
MAB_2114c|M.abscessus_ATCC_199 WADAAREI-----------------HSLRSELGYGDGYDVVYEATTDWSN
MLBr_00348|M.leprae_Br4923 FARTGARRSREDFEICASAQIVVTEDRAAAFAGIKPFLALYMGGMGAEGT
. .
Mb0978c|M.bovis_AF2122/97 ------------------------------------DKLARWAELGVTEV
Rv0953c|M.tuberculosis_H37Rv ------------------------------------DKLARWAELGVTEV
MSMEG_5715|M.smegmatis_MC2_155 RLRARQSPVAGEDAVDAMLSTMSAPESASGTPEQVIEKLKRVRDLGCEYA
TH_4607|M.thermoresistible__bu QVRARLVSRVGEDAADGMVDSIKAPSSATGTPDQVIERLQRMRDLGCEYA
Mflv_1696|M.gilvum_PYR-GCK RVRSRISDLTGEAAADAMLNAMNSPQAGSGTPEQLVESLQRLRDLGCEYV
Mvan_5062|M.vanbaalenii_PYR-1 RVRSRISALTGEPAADAMLNSMSSPEAGSGTPEQLIDTLRRLRELGCEYV
MMAR_4673|M.marinum_M RVRDRLVGYVPEAVADSMVGGLP--DSATGTPEQVIERLAQIRDLGCEYA
MUL_0292|M.ulcerans_Agy99 RVRDRLVGYVPEAVADSMVGGLP--DSATGTPEQVIERLAQIRDLGCEYA
MAV_0986|M.avium_104 RIRDRMAGYVGESAADAMIAGTSGVDSATGTTEQVIERLARLRDLGCDYV
MAB_2114c|M.abscessus_ATCC_199 -------------------------------LDATREKIATLHDGGYTWY
MLBr_00348|M.leprae_Br4923 NFHADVYRRMGYAEVVDEVTALFRSNQKDKAAEIIPNELVDSTMIVGDVD
: :
Mb0978c|M.bovis_AF2122/97 LFGMPDRSADDAAAYVERLAAKLACCV-------
Rv0953c|M.tuberculosis_H37Rv LFGMPDRSADDAAAYVERLAAKLACCV-------
MSMEG_5715|M.smegmatis_MC2_155 ILYFPEAAYDRSGIELFEQKVIPALS--------
TH_4607|M.thermoresistible__bu IMYFPEAAYDRSGIEMFEQKVIPALS--------
Mflv_1696|M.gilvum_PYR-GCK ICYFPEAAYDRSSIEMFEREIMPALA--------
Mvan_5062|M.vanbaalenii_PYR-1 ICYFPEAAYDRSGIELFEREVIPALS--------
MMAR_4673|M.marinum_M ICYFPEAAYDRSGIELFEREVIPALS--------
MUL_0292|M.ulcerans_Agy99 ICYFPEAAYDRSGIELFEREVIPALS--------
MAV_0986|M.avium_104 ICYFPEAAYDRSGIELFEREIIPALS--------
MAB_2114c|M.abscessus_ATCC_199 LDSDWHTEHDDPLAALRARVEIGPPR--------
MLBr_00348|M.leprae_Br4923 YVCKQIAAWSAAGVTMMMVSASSVEQVRDLAGLF
. . :