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MTDVQNHIGIDPASAPIEAPAAEAQVRADDRGHVFHSWSAQAMIDPLPIAGGSGATFWDYTGKEYLDFAS QLVNLNLGHQHPRLVESIQRQAGRLATIAPAFANDVRGELARLVAERAPGTLNKVFFTNGGTEAVEHAVR MARHHTGRRKVLAAYRSYHGGTTTSMSLTGEPRRWANDPGDNSVVHFFGPYAYRSVFHSTTPEEETQRAL EHLEQVINLEGPPTIAAIILESVVGTNGVLVPPPGYLAGVREICDRYGLVFIADEVMVGFGRFGEWFAIN AFDVTPDLITFAKGINSGYVPLGGVVISDAIATSFDHRPYPGGLTYSGHPLACAVGVETIKVFEDDQILK RVRDLGERVVRPELERWVQAHPSVGEIRGRGLFWAVELVRNKETREPLVPFNASGEAAAPMNAFAAACKK AGLWPFTHFNRTHVAPPLIISEEDLRRGLSIIDAALNVADGYVD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1703 | - | - | 100% (464) | aminotransferase |
| M. abscessus ATCC 19977 | MAB_4345c | - | e-162 | 61.06% (434) | hypothetical protein MAB_4345c |
| M. abscessus ATCC 19977 | MAB_3326c | - | 6e-58 | 33.78% (444) | hypothetical protein MAB_3326c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3362 | - | 2e-61 | 36.65% (412) | hypothetical protein Mb3362 |
| M. gilvum PYR-GCK | Mflv_0358 | - | 1e-162 | 60.62% (452) | hypothetical protein Mflv_0358 |
| M. tuberculosis H37Rv | Rv3329 | - | 2e-61 | 36.65% (412) | hypothetical protein Rv3329 |
| M. leprae Br4923 | MLBr_01409 | argD | 6e-45 | 30.38% (418) | acetylornithine aminotransferase |
| M. marinum M | MMAR_3558 | - | 1e-59 | 34.49% (432) | aminotransferase (adenosylmethionine-8-amino-7- oxononanoate) |
| M. avium 104 | MAV_4304 | - | 3e-64 | 37.04% (432) | hypothetical protein MAV_4304 |
| M. smegmatis MC2 155 | MSMEG_2450 | - | 1e-162 | 59.13% (460) | hypothetical protein MSMEG_2450 |
| M. thermoresistible (build 8) | TH_1978 | - | 6e-65 | 36.20% (442) | PROBABLE AMINOTRANSFERASE |
| M. ulcerans Agy99 | MUL_2791 | - | 2e-59 | 34.26% (432) | hypothetical protein MUL_2791 |
| M. vanbaalenii PYR-1 | Mvan_1823 | - | 1e-164 | 61.59% (453) | hypothetical protein Mvan_1823 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3362|M.bovis_AF2122/97 -------------------------------------MHFARHGAGIQHP
Rv3329|M.tuberculosis_H37Rv -------------------------------------MHFARHGAGIQHP
MAV_4304|M.avium_104 -------------------------------MTDHLWLHFARHGPGITPP
MMAR_3558|M.marinum_M ------------------------MTELSAKANRHLWGHFARHGAGITPP
MUL_2791|M.ulcerans_Agy99 ------------------------MTELSAKANRHLWGHFARHGAGITPP
TH_1978|M.thermoresistible__bu -----------------------MSTDRAAQADRHLWGHFARHGPGVTPP
MLBr_01409|M.leprae_Br4923 ----------------------MTPTQTNTATMQQRWETVMMNNYGTPPI
Mflv_0358|M.gilvum_PYR-GCK MTITDQPTDTAGLPTGEDLDSAIARGRRAYDLDRRHVFHSWSAQAQITPM
Mvan_1823|M.vanbaalenii_PYR-1 MTITEQPTDSTALPTGEDIDAAIARGQRAYELDRKHVFHSWSAQAQINPM
MSMEG_2450|M.smegmatis_MC2_155 MTAIQEST---LLPNGLTVDTAKAEAARAYELDRAHVFHSWSAQEEISPM
MAB_1703|M.abscessus_ATCC_1997 MTDVQNHIG--IDPASAPIEAPAAEAQVRAD-DRGHVFHSWSAQAMIDPL
Mb3362|M.bovis_AF2122/97 VIVRGDGVTIFDDRGKSYLDALSGLFVVQVGYGRAELAEAAARQAGTLGY
Rv3329|M.tuberculosis_H37Rv VIVRGDGVTIFDDRGKSYLDALSGLFVVQVGYGRAELAEAAARQAGTLGY
MAV_4304|M.avium_104 IITRGHGVTIYDDRGNSYLDGLSGLFTVQVGHGRAELAEAAARQAGTLAF
MMAR_3558|M.marinum_M IITRGEGVTIWDDRGNSYLDGLSGLFVVQAGHGRTELAEAAAKQAETLAF
MUL_2791|M.ulcerans_Agy99 IITRGEGVTIWDDRGNSYLDGLSGLFVVQAGHGRTELAEAAAKQAETLAF
TH_1978|M.thermoresistible__bu IIVRGDGVTIWDDHGRRYLDGLSGLFVVQAGHGRAELAEAAARQAGQLAY
MLBr_01409|M.leprae_Br4923 VLASGNGAVVTDVDSNTYLDLLGGIAVNVLGHRHPAVIEAVTHQITTLGH
Mflv_0358|M.gilvum_PYR-GCK TVLAAQGSYVWDGDGTRLLDFSSQLVNTNIGHQHPKVVAAIAEQAATLCT
Mvan_1823|M.vanbaalenii_PYR-1 TVLAAQGSYVWDGEGNKLLDFSSQLVNTNIGHQHPKVVAAIAEQAATLCT
MSMEG_2450|M.smegmatis_MC2_155 TVTAAQGSYLWDGDGNRLLDFSSQLVNTNIGHQHPKVVAAIAEQAAKLCT
MAB_1703|M.abscessus_ATCC_1997 PIAGGSGATFWDYTGKEYLDFASQLVNLNLGHQHPRLVESIQRQAGRLAT
: . * . * . ** . : *: :. : : .* *
Mb3362|M.bovis_AF2122/97 FPLWGYATPPAIELAERLARYAPGDLNRVFFTSGGTEAVETAWKVAKQYF
Rv3329|M.tuberculosis_H37Rv FPLWGYATPPAIELAERLARYAPGDLNRVFFTSGGTEAVETAWKVAKQYF
MAV_4304|M.avium_104 FPLWGYATPPAIELAERLAGYAPGDLNRVFFTTGGTEAVETAWKLAKQYF
MMAR_3558|M.marinum_M FPLWSYATPTAIELAERVAHYAPGDLNRVFFTTGGGEAVESAWKLAKQYF
MUL_2791|M.ulcerans_Agy99 FPLWSYATPTAIELAERVAHYAPGDLNRVFFTTGGGEAVESAWKLAKQYF
TH_1978|M.thermoresistible__bu FPLWSYATPPAIELAERIAHYAPGDLNRVFFTTGGGEAVESAWKLAKQYF
MLBr_01409|M.leprae_Br4923 TSNLYATEPSITLAEELVALLGADTQTRVFFCNSGTEANELAFKLSR---
Mflv_0358|M.gilvum_PYR-GCK IAPQ-HVNDVRSEAARLIAERTPGDLNRIFFTNGGADAVEHAVRMAR---
Mvan_1823|M.vanbaalenii_PYR-1 IAPQ-HVNDARSEAARLVAERTPGDLNRVFFTNGGADAVEHAVRMAR---
MSMEG_2450|M.smegmatis_MC2_155 VAPQ-HANAARSEAARLIAERTPGELNKIFFTNGGADAVEHAVRMAR---
MAB_1703|M.abscessus_ATCC_1997 IAPA-FANDVRGELARLVAERAPGTLNKVFFTNGGTEAVEHAVRMAR---
. . . :* .. .::** ..* :* * * ::::
Mb3362|M.bovis_AF2122/97 KLTGKPGKHKVISRSIAYHGTTQGALAITGLPLFKAPFEPLTPGGFRVPN
Rv3329|M.tuberculosis_H37Rv KLTGKPGKQKVISRSIAYHGTTQGALAITGLPLFKAPFEPLTPGGFRVPN
MAV_4304|M.avium_104 KLTGKPGKHKVISRAVAYHGTTQGALAITGLPRYKAPFEPVTPGGFRVPN
MMAR_3558|M.marinum_M KETGKPGKYKAISRSTAYHGTPHGALAITGLPAFKAPFEPLTPGGVRIPN
MUL_2791|M.ulcerans_Agy99 KETGKPGKYKAISRSTAYHGTPHGALAITGLPAFKAPFEPLTPGGVRIPN
TH_1978|M.thermoresistible__bu KLTGKPGKHKVVSRAVAYHGTPQGALAITGLPMFKAPFEPLTPGGFRVPN
MLBr_01409|M.leprae_Br4923 ----LTGRTKLVAAQAAFHGRTMGSLALTGQPAKQAAFEPLPGHVTHVPY
Mflv_0358|M.gilvum_PYR-GCK ---LHTGRYKVLSRYRSYHGGTETAINLTGDPRRWP--NDHGNAGIVHFD
Mvan_1823|M.vanbaalenii_PYR-1 ---LHTGRYKVLSRYRSYHGGTETAINLTGDPRRWP--NDHGNAGIVHFN
MSMEG_2450|M.smegmatis_MC2_155 ---LHTGRYKVLSRYRAYHGGTDTAINLTGDPRRWP--NDRGNSGIVHFN
MAB_1703|M.abscessus_ATCC_1997 ---HHTGRRKVLAAYRSYHGGTTTSMSLTGEPRRWA--NDPGDNSVVHFF
.*: * :: ::** . :: :** * . :
Mb3362|M.bovis_AF2122/97 TNFYRAP--LHTDLKEFGRWAADRIAEAIEFEGPDTVAAVFLEPVQNAGG
Rv3329|M.tuberculosis_H37Rv TNFYRAP--LHTDLKEFGRWAADRIAEAIEFEGPDTVAAVFLEPVQNAGG
MAV_4304|M.avium_104 TNFYRAPEAFANDPKGFGLWAADRIAEAIEFEGPDTVAAVFVEPVQNAGG
MMAR_3558|M.marinum_M TNFYRAPAPYADDSKEFGLWAANRIAEAIEFEGPDTVAAVFLEPVQNAGG
MUL_2791|M.ulcerans_Agy99 TNFYRAPAPYADDSKDFGLWAANRIAEAIEFEGPDTVAAVFLEPVQNAGG
TH_1978|M.thermoresistible__bu TNFYRAPAPYRDDEKAFGRYCADRIAETIEFEGPDTVAAVVLEPVQNAGG
MLBr_01409|M.leprae_Br4923 G-------------------QVDALAAAVDN----DTAAVFLEPIMGESG
Mflv_0358|M.gilvum_PYR-GCK GPFLYRSTFHADTEEQETQRALEHLDRLIRMEGPSTIAAIILESVPGTAG
Mvan_1823|M.vanbaalenii_PYR-1 GPFLYRSAFHAETEEQETQRALEHLDRLVQMEGPSTIAAIILESVPGTAG
MSMEG_2450|M.smegmatis_MC2_155 GPFLYRSSFYAETEEQESQRALEYLEKLIQMEGPSTIAAIILESIPGTAG
MAB_1703|M.abscessus_ATCC_1997 GPYAYRSVFHSTTPEEETQRALEHLEQVINLEGPPTIAAIILESVVGTNG
: : : **:.:*.: . *
Mb3362|M.bovis_AF2122/97 CIPAPPGYFERVREICDRYDVLLVSDEVICAFGRIGSMFACEDLGYVPDM
Rv3329|M.tuberculosis_H37Rv CIPAPPGYFERVREICDRYDVLLVSDEVICAFGRIGSMFACEDLGYVPDM
MAV_4304|M.avium_104 SIPPPPGYFERVREICDRYDVLLVSDEVICAFGRIGSMFACADFGYVPDM
MMAR_3558|M.marinum_M CFPPPPGYFERVREICDEYDVLLVSDEVICAFGRIGSMFACNDFGYVPDI
MUL_2791|M.ulcerans_Agy99 CFPPPPGYFERVREICDEYDVLLVSDEVICAFGRIGSMFACNDFGYVPDI
TH_1978|M.thermoresistible__bu CIPPPPGYFERVREICDTYDVLLISDEVICAFGRIGSMFACDDFGYQPDI
MLBr_01409|M.leprae_Br4923 VIVPPEGYLAAARDITTRHGALLVIDEVQTGIGRTGAFFAHQHDSITPDV
Mflv_0358|M.gilvum_PYR-GCK IMVPPPGYMAGVREICDRHGIVFIADEVMAGFGRTGTWFAIDNFGVVPDL
Mvan_1823|M.vanbaalenii_PYR-1 IMVPPPGYMAGVREICDRHGIVFIADEVMAGFGRTGTWFAIENFDVVPDL
MSMEG_2450|M.smegmatis_MC2_155 IMVPPPGYLAGVRELCTRYGIVFIADEVMAGFGRSGKWFSINHFDVVPDL
MAB_1703|M.abscessus_ATCC_1997 VLVPPPGYLAGVREICDRYGLVFIADEVMVGFGRFGEWFAINAFDVTPDL
: .* **: .*:: :. ::: *** .:** * *: . **:
Mb3362|M.bovis_AF2122/97 ITCAKGLTSGYSPLGAMIASDRLFEPFNDGETMFAHGYTFGGHPVSAAVG
Rv3329|M.tuberculosis_H37Rv ITCAKGLTSGYSPLGAMIASDRLFEPFNDGETMFAHGYTFGGHPVSAAVG
MAV_4304|M.avium_104 ITCAKGMTSGYSPIGAMIASERLFEPFADGDTMFPHGYTFGGHPVSAAVG
MMAR_3558|M.marinum_M ITCAKGMTSGYSPIGAMVASDRLFEPFNDGKTTFAHGYTFGGHPVSSAVA
MUL_2791|M.ulcerans_Agy99 ITCAKGMTSGYSPIGAMVASDRLFEPFNDGKTTFAHGYTFGGHPVSSAVA
TH_1978|M.thermoresistible__bu ITCAKGLTSGYAPLGAMIATDRLFEPFADGKTVFPHGYTFGGHPVSAAVA
MLBr_01409|M.leprae_Br4923 VTLAKGLGGG-LPIGAFLATG----PAAELLTLGLHGSTFGGNPVCTAAA
Mflv_0358|M.gilvum_PYR-GCK ITFAKGVTSGYVPLGGVAINDAIYSTFADR--AYPGGLTYSGHPLACACA
Mvan_1823|M.vanbaalenii_PYR-1 ITFAKGITSGYVPLGGVAINDAIYSTFADR--AYPGGLTYSGHPLATACA
MSMEG_2450|M.smegmatis_MC2_155 MTFAKGVNSGYVPLGGVAISPEIYETFAHR--AYPGGLTYSGHPLACAAA
MAB_1703|M.abscessus_ATCC_1997 ITFAKGINSGYVPLGGVVISDAIATSFDHR--PYPGGLTYSGHPLACAVG
:* ***: .* *:*.. . . . * *:.*:*:. * .
Mb3362|M.bovis_AF2122/97 LANLDIFEREGLSDHVKRNSPALR--ATLEKLYDLPIVGDIRGEGYFFGI
Rv3329|M.tuberculosis_H37Rv LANLDIFEREGLSDHVKRNSPALR--ATLEKLYDLPIVGDIRGEGYFFGI
MAV_4304|M.avium_104 LVNLDIFEREGLNDRVRTLAPTFR--ATLEKLYDLPIVGDVRGEGFFYGV
MMAR_3558|M.marinum_M LANLDIFEREGLNDHVKQNAPAFR--TTLEKLLDLPIVGDVRGEGFFYGI
MUL_2791|M.ulcerans_Agy99 LANLDIFEREGLNDHVKQNAPAFR--TTLEKLLDLPIVGDVRGEGFFYGI
TH_1978|M.thermoresistible__bu LANLDIFEREGLNDRVRTLSPLLR--ATLERLYELPIVGDVRGEGYFFAV
MLBr_01409|M.leprae_Br4923 LAVLRVLATQGLVRRAEVLGDSMR--IGIESLS-HPLIDQVRGRGLLLGI
Mflv_0358|M.gilvum_PYR-GCK VATITAMEDEGMVANAARIGREVLGPGLRELAARHRSVGEVRGLGVFWAV
Mvan_1823|M.vanbaalenii_PYR-1 VATINAMEDEGMVANAARIGERVLGPGLRELAARHRSVGEVRGLGVFWAI
MSMEG_2450|M.smegmatis_MC2_155 VATINAMEDEGMVENAAKVGAEVIGPGLAELAAKHRSVGEVRGLGVFWAV
MAB_1703|M.abscessus_ATCC_1997 VETIKVFEDDQILKRVRDLGERVVRPELERWVQAHPSVGEIRGRGLFWAV
: : : : : .. . . . :.::** * : .:
Mb3362|M.bovis_AF2122/97 ELVKDQATKQTFTDDERARLL-GQVSAALFEAGLYCRTDDRGDPVVQVAP
Rv3329|M.tuberculosis_H37Rv ELVKDQATKQTFTDDERARLL-GQVSAALFEAGLYCRTDDRGDPVVQVAP
MAV_4304|M.avium_104 ELVKDRATKQTFTDSERRALL-GRVGAALFEAGLYCRTDDRGDSVIQLAP
MMAR_3558|M.marinum_M ELVKDKDTKATFSDEESERLLRGFLSSALLEAGLYCRADDRGDPVVQLAP
MUL_2791|M.ulcerans_Agy99 ELVKDKDTKATFSDEESERLLRGFLSSALLEAGLYCRADDRGDPVVQLAP
TH_1978|M.thermoresistible__bu ELVQDKAGRQPFSAEESARLV-AHLNRALLDAGLYCRADNRGDTVVQVAP
MLBr_01409|M.leprae_Br4923 VLTAPRAKD---------------IEKAARDAGFLVNATAP--EVIRLAP
Mflv_0358|M.gilvum_PYR-GCK ELVANQQTREPLAPYGGS---SPAMNAVVAACKSGGLLPFANFNRIHAVP
Mvan_1823|M.vanbaalenii_PYR-1 ELVANRETREPLAPYGGS---SPAMAAVLAACKSGGLLPFANFNRIHAVP
MSMEG_2450|M.smegmatis_MC2_155 ELVKDQKTREPLAPYGSS---SPAMNAVIAACKSGGLLPFANFNRIHVVP
MAB_1703|M.abscessus_ATCC_1997 ELVRNKETREPLVPFNASGEAAAPMNAFAAACKKAGLWPFTHFNRTHVAP
*. : : . : .*
Mb3362|M.bovis_AF2122/97 PLISGQPEFDTIETILRSVLTDTGRKYLHL-
Rv3329|M.tuberculosis_H37Rv PLISGQPEFDTIETILRSVLTDTGRKYLHL-
MAV_4304|M.avium_104 PLISGQAEFDTIEAALRGVLSDECRRL----
MMAR_3558|M.marinum_M PLISGQQEFDKMEQILRGVLSEAWSRL----
MUL_2791|M.ulcerans_Agy99 PLISGQQEFDKMEQILRGVLSEAWSRL----
TH_1978|M.thermoresistible__bu PLISGPAEFDAMHDILRTVLKDAPNHV----
MLBr_01409|M.leprae_Br4923 PLIITESQIDSFITALPGILDASIAELGKKA
Mflv_0358|M.gilvum_PYR-GCK PCNVTDDEVAEGLRILDAALSVADDYTV---
Mvan_1823|M.vanbaalenii_PYR-1 PCNVTDDEVAEGLRILDAALSVADEYVV---
MSMEG_2450|M.smegmatis_MC2_155 PCNVSADEAREGLAILDSALDVADEHTV---
MAB_1703|M.abscessus_ATCC_1997 PLIISEEDLRRGLSIIDAALNVADGYVD---
* : : *