For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
AKDVSAVRIVRASDRWHWRNEWLESWQSFPVTGNFDLAGNAHGLLMVNNEDTIDPGEGFDAHTHRNTEII TWVLEGTAVHKDSLGNSGEIRPGVVQRMSAGTGITHTERNGAGRLERQQLHVVQMWIPPDEIDRAPSYQE SDITSDLRRNTLLPIASGMPKYSGDAAISFGNRYATLHVALLDPRRSVNVPDALYGHVFVSRGQAEFEGQ GLLQQGDAVRLTRSGGHRVSATDEGAELLIWEMHGTAINV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1564c | - | - | 100% (251) | putative pirin-like protein |
| M. abscessus ATCC 19977 | MAB_4561 | - | 3e-55 | 45.04% (242) | hypothetical protein MAB_4561 |
| M. abscessus ATCC 19977 | MAB_2446c | - | 2e-10 | 30.87% (149) | putative pirin-like protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0187c | - | 1e-53 | 46.25% (240) | hypothetical protein Mb0187c |
| M. gilvum PYR-GCK | Mflv_0696 | - | 2e-68 | 50.80% (250) | pirin domain-containing protein |
| M. tuberculosis H37Rv | Rv0181c | - | 1e-53 | 46.25% (240) | hypothetical protein Rv0181c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0424 | - | 3e-54 | 46.86% (239) | hypothetical protein MMAR_0424 |
| M. avium 104 | MAV_5002 | - | 2e-53 | 48.31% (236) | YhhW protein |
| M. smegmatis MC2 155 | MSMEG_0215 | - | 5e-60 | 50.00% (240) | YhhW family protein |
| M. thermoresistible (build 8) | TH_0606 | - | 6e-67 | 50.84% (238) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0039 | - | 1e-08 | 36.99% (73) | hypothetical protein MUL_0039 |
| M. vanbaalenii PYR-1 | Mvan_0147 | - | 1e-68 | 52.24% (245) | pirin domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0696|M.gilvum_PYR-GCK MTRSTSVIDVRRADERAKTAIEWLDSKHSFSFGSHYDPDNTHHG-LLLVN
Mvan_0147|M.vanbaalenii_PYR-1 MTTSPSIVNVRRADDRAKTRIAWLDSKHSFSFGSHYEPDNTHHG-LLLVN
TH_0606|M.thermoresistible__bu --MPAETMDIRWAGDRFATTIDWLDSRHSFSFADHYDPANTHHG-VLLVN
MSMEG_0215|M.smegmatis_MC2_155 ---MPPTVDIRRADQRGVSVTDWLQSRHSFSFGDYYDPANTHHG-LLLVN
Mb0187c|M.bovis_AF2122/97 ---MTATVEIRRAADRAVTTTSWLKSRHSFSFGDHYDPDNTHHG-LLLVN
Rv0181c|M.tuberculosis_H37Rv ---MTATVEIRRAADRAVTTTSWLKSRHSFSFGDHYDPDNTHHG-LLLVN
MMAR_0424|M.marinum_M ---MPATVQIRRAADRAVTTTSWLTSRHSFSFGDHYDPDNTHHG-LLLVS
MAV_5002|M.avium_104 ---MSAGFEIRRAATRAVTTTPWLTSRHSFSFGDHYDPDNTHFG-LLLVN
MAB_1564c|M.abscessus_ATCC_199 MAKDVSAVRIVRASDRWHWRNEWLESWQSFPVTGNFDLAGNAHG-LLMVN
MUL_0039|M.ulcerans_Agy99 -------MPVSRCCIR--GKCRWVGRVQSGCNARFRSGRRSLIGAWCFVD
. : . * *: :* . . * :*.
Mflv_0696|M.gilvum_PYR-GCK NDDIVTPGAGFDTHPHRDMEIVTWVLRGSLVHQDSTGHSGVIYPGLAQRM
Mvan_0147|M.vanbaalenii_PYR-1 NDDTVKPGTGFDTHPHRDMEIVTWVLRGSLVHQDSTGNSGVIYPGLAQRM
TH_0606|M.thermoresistible__bu NDDRVAPGTGFDTHPHRDMEIVTWVLQGSLVHQDSEGNAGVIYPGLAQRM
MSMEG_0215|M.smegmatis_MC2_155 NDDIVAAGGGFDTHPHRDMEIVTWVLDGELAHADSMGNSGVIYPGLAQRM
Mb0187c|M.bovis_AF2122/97 NDDQMEPASGFDPHPHRDMEIVTWVLRGALRHQDSAGNSGVIYPGLAQRM
Rv0181c|M.tuberculosis_H37Rv NDDQMEPASGFDPHPHRDMEIVTWVLRGALRHQDSAGNSGVIYPGLAQRM
MMAR_0424|M.marinum_M NDDVVQPRSGFDTHPHRDMEIVTWVLEGELTHRDSTGNHGVIYPGLAQRM
MAV_5002|M.avium_104 NDDIVSPGTGFDTHPHRDMEIVTWVLAGALAHQDSTGNRGVVYPGLAQRM
MAB_1564c|M.abscessus_ATCC_199 NEDTIDPGEGFDAHTHRNTEIITWVLEGTAVHKDSLGNSGEIRPGVVQRM
MUL_0039|M.ulcerans_Agy99 HYGPVSAHMDVAPHPHTGLQTVSWLFSGEVEHRDSAGVHARIRPGELNMM
: . : . .. .*.* . : ::*:: * * ** * . : ** : *
Mflv_0696|M.gilvum_PYR-GCK SAGRGILHSEKNDSWTLTG------------QQSHSEPVHFVQMWVVPD-
Mvan_0147|M.vanbaalenii_PYR-1 SAGRGIMHSEKNDSWTLTG------------RESHSEPVHFVQMWVVPD-
TH_0606|M.thermoresistible__bu SAGSGILHSEKNDSWTLTG------------EQPHREPVRFIQMWVLPD-
MSMEG_0215|M.smegmatis_MC2_155 SAGTGVQHSEKN--------------------ASSDKPVHFVQMWVIPD-
Mb0187c|M.bovis_AF2122/97 SAGTGILHSEMN--------------------DSATEPVHFVQMWVIPD-
Rv0181c|M.tuberculosis_H37Rv SAGTGILHSEMN--------------------DSATEPVHFVQMWVIPD-
MMAR_0424|M.marinum_M SAGSGILHSETN--------------------DSQSQPVHFVQMWVAPD-
MAV_5002|M.avium_104 SAGRGILHSERN--------------------DSPSLPVHFVQMWVIPD-
MAB_1564c|M.abscessus_ATCC_199 SAGTGITHTERNGAG-----------------RLERQQLHVVQMWIPPD-
MUL_0039|M.ulcerans_Agy99 TAGAGICHSEVSVGSGVLHGAQLWVALPDSVRDTGRDFAHYAPAPAVLPG
:** *: *:* . :
Mflv_0696|M.gilvum_PYR-GCK ------------------------------------ESGIQPGYQQ-LEI
Mvan_0147|M.vanbaalenii_PYR-1 ------------------------------------ESGREPGYQQ-LEI
TH_0606|M.thermoresistible__bu ------------------------------------EYGVTPSYEQ-LEI
MSMEG_0215|M.smegmatis_MC2_155 ------------------------------------RAGLTPGYEQ-REI
Mb0187c|M.bovis_AF2122/97 ------------------------------------ATGITASYQQ-QEI
Rv0181c|M.tuberculosis_H37Rv ------------------------------------ATGITASYQQ-QEI
MMAR_0424|M.marinum_M ------------------------------------ETGITPSYQQ-REI
MAV_5002|M.avium_104 ------------------------------------EAGIDPSYQQ-HEI
MAB_1564c|M.abscessus_ATCC_199 ------------------------------------EIDRAPSYQE-SDI
MUL_0039|M.ulcerans_Agy99 ARARVFIGELAGVRSPVHTFTPLLGAQLDLDAHAELDIEVDPTFEHGVLC
. ::.
Mflv_0696|M.gilvum_PYR-GCK DDELLRGNLVTIASGMPEHSDDAAITIRNRYAALHGARLEPGQSVQLPDA
Mvan_0147|M.vanbaalenii_PYR-1 DDELLRGNLVTIASGMPAHSDAAAIAIGNRYAALHGARLQPGQSIQLPEA
TH_0606|M.thermoresistible__bu EDARLRSGLIPIASGMPRYRGETAITIGNRHAALHGARMAPGDSVRLPEA
MSMEG_0215|M.smegmatis_MC2_155 T---LAENLTPIASG----AGDAAVTLHNRNATLYGARLRPGDAVGLPEA
Mb0187c|M.bovis_AF2122/97 DDELLRAGLVTIASGIP--GQDAALTLHNSSASLHGARLRPGATVSLPCA
Rv0181c|M.tuberculosis_H37Rv DDELLRAGLVTIASGIP--GQDAALTLHNSSASLHGARLRPGATVSLPCA
MMAR_0424|M.marinum_M DHRLFDGGLVTVASGIP--GQDAAITLHNRHAALHCARLRPGDTIDLPSA
MAV_5002|M.avium_104 DDTALGGGLVTIASGIR--GHDAAISLHNRNAALHGARLPAAAAVDLPAA
MAB_1564c|M.abscessus_ATCC_199 TSDLRRNTLLPIASGMPKYSGDAAISFGNRYATLHVALLDPRRSVNVPDA
MUL_0039|M.ulcerans_Agy99 DVGDLELAGTALAAGDLGYQGPDNTAVHVRNVGAQPARLLLLGGTPFAEE
.:*:* :. . * : ..
Mflv_0696|M.gilvum_PYR-GCK PYLHL-FVPRGTVTLEGAGALQEGDAVRFTATGGQR--ITAT-TPAEILV
Mvan_0147|M.vanbaalenii_PYR-1 PYLHL-FVPRGEVSLEGAGPLREGDAVRFTASGGQR--VTAT-APAEILV
TH_0606|M.thermoresistible__bu RYLHL-FIARGAVTLEGAGALGEGDAVRFTASGGHR--VTAT-GPAEILV
MSMEG_0215|M.smegmatis_MC2_155 RYVHL-FVARGRVTLEDAGDLAEGDAARLTGSGGQR--VTATDEPAEILV
Mb0187c|M.bovis_AF2122/97 PFLHL-FVAYGRLTLEGGGELADGDAVRFTDADARG--LTAN-EPSEVLI
Rv0181c|M.tuberculosis_H37Rv PFLHL-FVAYGRLTLEGGGELADGDAVRFTDADARG--LTAN-EPSEVLI
MMAR_0424|M.marinum_M SYLHL-FVARGRLGLESFGDVSTGDAVRFTDVEAPR--LSAH-APAEVLI
MAV_5002|M.avium_104 PYLHV-FLARGRADIEDVGELHPGDAVRFTDTDGRR--VTGL-EPSELLI
MAB_1564c|M.abscessus_ATCC_199 LYGHV-FVSRGQAEFEGQGLLQQGDAVRLTRSGGHR--VSATDEGAELLI
MUL_0039|M.ulcerans_Agy99 LVMWWNFVGRNHDEIVSYRQLWQDDDARFGEVVGYQGSVTRLPAPPLPTT
*: . : . : .* .*: . :: .
Mflv_0696|M.gilvum_PYR-GCK WEMHAGIGAA----
Mvan_0147|M.vanbaalenii_PYR-1 WEMHAGLGAA----
TH_0606|M.thermoresistible__bu WEMHTGLGG-----
MSMEG_0215|M.smegmatis_MC2_155 WEMHASLAGD----
Mb0187c|M.bovis_AF2122/97 WEMHAKLGDSAT--
Rv0181c|M.tuberculosis_H37Rv WEMHAKLGDSAT--
MMAR_0424|M.marinum_M WEMRAILGS-----
MAV_5002|M.avium_104 WEMHARLGG-----
MAB_1564c|M.abscessus_ATCC_199 WEMHGTAINV----
MUL_0039|M.ulcerans_Agy99 RLLPRPLPNREDHR
: